LOCUS       NM_019759               1713 bp    mRNA    linear   ROD 16-OCT-2024
DEFINITION  Mus musculus dermatopontin (Dpt), mRNA.
ACCESSION   NM_019759
VERSION     NM_019759.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1713)
  AUTHORS   Ortiz-Munoz,G., Brown,M., Carbone,C.B., Pechuan-Jorge,X.,
            Rouilly,V., Lindberg,H., Ritter,A.T., Raghupathi,G., Sun,Q.,
            Nicotra,T., Mantri,S.R., Yang,A., Doerr,J., Nagarkar,D.,
            Darmanis,S., Haley,B., Mariathasan,S., Wang,Y., Gomez-Roca,C., de
            Andrea,C.E., Spigel,D., Wu,T., Delamarre,L., Schoneberg,J.,
            Modrusan,Z., Price,R., Turley,S.J., Mellman,I. and Moussion,C.
  TITLE     In situ tumour arrays reveal early environmental control of cancer
            immunity
  JOURNAL   Nature 618 (7966), 827-833 (2023)
   PUBMED   37258670
REFERENCE   2  (bases 1 to 1713)
  AUTHORS   Kurz,J., Weiss,A.C., Ludtke,T.H., Deuper,L., Trowe,M.O.,
            Thiesler,H., Hildebrandt,H., Heineke,J., Duncan,S.A. and Kispert,A.
  TITLE     GATA6 is a crucial factor for Myocd expression in the visceral
            smooth muscle cell differentiation program of the murine ureter
  JOURNAL   Development 149 (15) (2022)
   PUBMED   35905011
REFERENCE   3  (bases 1 to 1713)
  AUTHORS   Kurz,J., Weiss,A.C., Thiesler,H., Qasrawi,F., Deuper,L., Kaur,J.,
            Rudat,C., Ludtke,T.H., Wojahn,I., Hildebrandt,H., Trowe,M.O. and
            Kispert,A.
  TITLE     Notch signaling is a novel regulator of visceral smooth muscle cell
            differentiation in the murine ureter
  JOURNAL   Development 149 (4) (2022)
   PUBMED   35103284
REFERENCE   4  (bases 1 to 1713)
  AUTHORS   Farmer,D.T., Mlcochova,H., Zhou,Y., Koelling,N., Wang,G.,
            Ashley,N., Bugacov,H., Chen,H.J., Parvez,R., Tseng,K.C.,
            Merrill,A.E., Maxson,R.E. Jr., Wilkie,A.O.M., Crump,J.G. and
            Twigg,S.R.F.
  TITLE     The developing mouse coronal suture at single-cell resolution
  JOURNAL   Nat Commun 12 (1), 4797 (2021)
   PUBMED   34376651
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1713)
  AUTHORS   Buechler,M.B., Pradhan,R.N., Krishnamurty,A.T., Cox,C.,
            Calviello,A.K., Wang,A.W., Yang,Y.A., Tam,L., Caothien,R.,
            Roose-Girma,M., Modrusan,Z., Arron,J.R., Bourgon,R., Muller,S. and
            Turley,S.J.
  TITLE     Cross-tissue organization of the fibroblast lineage
  JOURNAL   Nature 593 (7860), 575-579 (2021)
   PUBMED   33981032
REFERENCE   6  (bases 1 to 1713)
  AUTHORS   Li,J., Willingham,E. and Baskin,L.S.
  TITLE     Gene expression profiles in mouse urethral development
  JOURNAL   BJU Int 98 (4), 880-885 (2006)
   PUBMED   16978288
REFERENCE   7  (bases 1 to 1713)
  AUTHORS   Cooper,L.J., Bentley,A.J., Nieduszynski,I.A., Talabani,S.,
            Thomson,A., Utani,A., Shinkai,H., Fullwood,N.J. and Brown,G.M.
  TITLE     The role of dermatopontin in the stromal organization of the cornea
  JOURNAL   Invest Ophthalmol Vis Sci 47 (8), 3303-3310 (2006)
   PUBMED   16877395
REFERENCE   8  (bases 1 to 1713)
  AUTHORS   Jones,G.C., Seyfried,N.T. and Bastow,E.R.
  TITLE     British Society for Matrix Biology meeting. Manchester, 5-6 april
            2004. Abstracts
  JOURNAL   Int J Exp Pathol 85 (4), A45-A77 (2004)
   PUBMED   15312129
REFERENCE   9  (bases 1 to 1713)
  AUTHORS   Tzen,C.Y. and Huang,Y.W.
  TITLE     Cloning of murine early quiescence-1 gene: the murine counterpart
            of dermatopontin gene can induce and be induced by cell quiescence
  JOURNAL   Exp Cell Res 294 (1), 30-38 (2004)
   PUBMED   14980498
  REMARK    GeneRIF: Cloning of early quiescence-1 gene: Identification of a
            role in cell quiescence.
REFERENCE   10 (bases 1 to 1713)
  AUTHORS   Takeda,U., Utani,A., Wu,J., Adachi,E., Koseki,H., Taniguchi,M.,
            Matsumoto,T., Ohashi,T., Sato,M. and Shinkai,H.
  TITLE     Targeted disruption of dermatopontin causes abnormal collagen
            fibrillogenesis
  JOURNAL   J Invest Dermatol 119 (3), 678-683 (2002)
   PUBMED   12230512
  REMARK    GeneRIF: Targeted disruption of dermatopontin causes abnormal
            collagen fibrillogenesis
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC137884.9.
            
            On Feb 17, 2018 this sequence version replaced NM_019759.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC046420.1, AF143374.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-374               AC137884.9         97970-98343
            375-500             AC137884.9         110213-110338
            501-608             AC137884.9         120202-120309
            609-1713            AC137884.9         124477-125581
FEATURES             Location/Qualifiers
     source          1..1713
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 72.12 cM"
     gene            1..1713
                     /gene="Dpt"
                     /gene_synonym="1810032B19Rik; 5033416F05Rik; EQ-1; Eq1"
                     /note="dermatopontin"
                     /db_xref="GeneID:56429"
                     /db_xref="MGI:MGI:1928392"
     exon            1..374
                     /gene="Dpt"
                     /gene_synonym="1810032B19Rik; 5033416F05Rik; EQ-1; Eq1"
                     /inference="alignment:Splign:2.1.0"
     CDS             70..675
                     /gene="Dpt"
                     /gene_synonym="1810032B19Rik; 5033416F05Rik; EQ-1; Eq1"
                     /note="early quiescence protein-1; TRAMP; tyrosine-rich
                     acidic matrix protein"
                     /codon_start=1
                     /product="dermatopontin precursor"
                     /protein_id="NP_062733.1"
                     /db_xref="CCDS:CCDS15437.1"
                     /db_xref="GeneID:56429"
                     /db_xref="MGI:MGI:1928392"
                     /translation="MDLTLLWVLLPLVTTAWGQYGGYGYPYQQYQDYGDDGWVNLNRQ
                     GFSYQCPHGQVVVAVRSIFSKKEGSDRQWNYACMPTPQSLGEPTECWWEEINRAGMEW
                     YQKCSNNGLVAGFQSRYFESVLDREWQFYCCRYSKRCPYSCWMTTEYPSHYGEDMDMI
                     SYDYDFYMRGATTTFSAVERDRQWKFIMCRMTDYDCEFENV"
     exon            375..500
                     /gene="Dpt"
                     /gene_synonym="1810032B19Rik; 5033416F05Rik; EQ-1; Eq1"
                     /inference="alignment:Splign:2.1.0"
     exon            501..608
                     /gene="Dpt"
                     /gene_synonym="1810032B19Rik; 5033416F05Rik; EQ-1; Eq1"
                     /inference="alignment:Splign:2.1.0"
     exon            609..1713
                     /gene="Dpt"
                     /gene_synonym="1810032B19Rik; 5033416F05Rik; EQ-1; Eq1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      851..856
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Dpt"
                     /gene_synonym="1810032B19Rik; 5033416F05Rik; EQ-1; Eq1"
                     /note="hexamer: AATAAA"
     polyA_site      871
                     /gene="Dpt"
                     /gene_synonym="1810032B19Rik; 5033416F05Rik; EQ-1; Eq1"
                     /note="major polyA site"
     regulatory      1682..1687
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Dpt"
                     /gene_synonym="1810032B19Rik; 5033416F05Rik; EQ-1; Eq1"
                     /note="hexamer: AATAAA"
     polyA_site      1713
                     /gene="Dpt"
                     /gene_synonym="1810032B19Rik; 5033416F05Rik; EQ-1; Eq1"
ORIGIN      
        1 cagcggcagc tgtataaagt cagcccagca aactgagggt gacatttttt ttgccagaag
       61 ccgggcagta tggacctcac tcttctgtgg gttcttctgc cactggtgac cacagcctgg
      121 ggccagtatg gtggctacgg gtacccatac cagcagtacc aggactacgg tgatgatgga
      181 tgggtgaatc ttaaccgcca aggcttcagc taccagtgtc cccacgggca agtggtggta
      241 gctgtgagga gcatctttag caagaaggaa ggctctgaca gacaatggaa ctatgcctgc
      301 atgcctacac cccaaagcct gggggagccc actgagtgct ggtgggagga gatcaacagg
      361 gccggcatgg aatggtacca gaagtgctcc aacaatggat tggtggcggg gttccagagc
      421 cgctacttcg aatcagtgct ggatcgtgag tggcaatttt actgctgccg ctatagcaag
      481 aggtgtccat attcctgctg gatgacaaca gagtacccaa gccactatgg ggaagacatg
      541 gacatgattt cctatgacta cgatttttat atgcgaggag caacaaccac tttctctgca
      601 gtggaaaggg atcgccagtg gaagttcatc atgtgccgga tgactgacta cgactgcgaa
      661 ttcgaaaacg tttaggctcg ccgcgtacag aagtccgggt gaagggtcag ggcccaggtg
      721 tcctgagggt gtcatatcac atatgttaat attgattaga acatctacac ttctttcttt
      781 tgctctcttc cctgggatgg gagctatggt gtcggctgcc taggcctttc tcaccacgat
      841 cacacatata aataaactca caattaagcc atgtttctcc ctttcaacac attccaagac
      901 aatcatgtct agttgctgat ggcagcttcc ttgcacagca catgtacaga gcctgcatgc
      961 ttacagcctg ccacccggag cacctgtcgc agccttgctg tgattcgcac tataacttga
     1021 gcttcagatt cagcttcgtg aacttggaga gaaagaagga gcttgagaga ggtgggataa
     1081 aggttctctg tagccaagtc tgtttgagtg acagcaccta gagacctcac ctggggtggt
     1141 ggggggtcac tctctgtctt gagggaacac gtctactctc tccttccaca aaagccacat
     1201 agacttagaa gttcaagtaa agatctatgt gcttcagaag agaggggact tggaggtgaa
     1261 agggggaggt gggagggttt gaggactgag ctgaaagact ttagacagaa agaacgtcct
     1321 ctattcaaag atatacacca gcagacccaa cagtgagaat gaatatgagg gccaggaaaa
     1381 cctgtgcgaa tcagtctcaa gacagaaaca atgaaagaaa gataagtgaa tgagattcac
     1441 attgggaacc tggggagaca agagtggtca gaggagaaga gatcttgggt tatcagcagc
     1501 ttgagacaca cccagtattc atatgaagac tgtaatatcc ctagaagcca tagggacgcc
     1561 atctctggat tggtcctgaa ggataattct ccctttccca tggcacttga aagtgtattc
     1621 tgcagagatg acactgtaat atctctgtct ctagccattt gtaccttctt ctttaaaaaa
     1681 aaataaaagt atcaatattc actgtgccat aaa
//
