LOCUS       NM_028615               1941 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus developmental pluripotency associated 2 (Dppa2), mRNA.
ACCESSION   NM_028615 XM_129276 XM_358869 XM_489583
VERSION     NM_028615.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1941)
  AUTHORS   Kubinyecz,O., Santos,F., Drage,D., Reik,W. and
            Eckersley-Maslin,M.A.
  TITLE     Maternal Dppa2 and Dppa4 are dispensable for zygotic genome
            activation but important for offspring survival
  JOURNAL   Development 148 (24) (2021)
   PUBMED   34931676
  REMARK    GeneRIF: Maternal Dppa2 and Dppa4 are dispensable for zygotic
            genome activation but important for offspring survival.
REFERENCE   2  (bases 1 to 1941)
  AUTHORS   Chen,Z., Xie,Z. and Zhang,Y.
  TITLE     DPPA2 and DPPA4 are dispensable for mouse zygotic genome activation
            and pre-implantation development
  JOURNAL   Development 148 (24) (2021)
   PUBMED   34878123
  REMARK    GeneRIF: DPPA2 and DPPA4 are dispensable for mouse zygotic genome
            activation and pre-implantation development.
REFERENCE   3  (bases 1 to 1941)
  AUTHORS   Li,H., Long,C., Xiang,J., Liang,P., Li,X. and Zuo,Y.
  TITLE     Dppa2/4 as a trigger of signaling pathways to promote zygote genome
            activation by binding to CG-rich region
  JOURNAL   Brief Bioinform 22 (4) (2021)
   PUBMED   33316032
  REMARK    GeneRIF: Dppa2/4 as a trigger of signaling pathways to promote
            zygote genome activation by binding to CG-rich region.
REFERENCE   4  (bases 1 to 1941)
  AUTHORS   Wu,Y., Dong,J., Feng,S., Zhao,Q., Duan,P., Xiong,M., Wen,Y., Lv,C.,
            Wang,X. and Yuan,S.
  TITLE     Maternal UHRF1 Is Essential for Transcription Landscapes and
            Repression of Repetitive Elements During the Maternal-to-Zygotic
            Transition
  JOURNAL   Front Cell Dev Biol 8, 610773 (2021)
   PUBMED   33634103
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1941)
  AUTHORS   Gretarsson,K.H. and Hackett,J.A.
  TITLE     Dppa2 and Dppa4 counteract de novo methylation to establish a
            permissive epigenome for development
  JOURNAL   Nat Struct Mol Biol 27 (8), 706-716 (2020)
   PUBMED   32572256
  REMARK    GeneRIF: Dppa2 and Dppa4 counteract de novo methylation to
            establish a permissive epigenome for development.
REFERENCE   6  (bases 1 to 1941)
  AUTHORS   Western,P.S., Ralli,R.A., Wakeling,S.I., Lo,C., van den
            Bergen,J.A., Miles,D.C. and Sinclair,A.H.
  TITLE     Mitotic arrest in teratoma susceptible fetal male germ cells
  JOURNAL   PLoS One 6 (6), e20736 (2011)
   PUBMED   21674058
REFERENCE   7  (bases 1 to 1941)
  AUTHORS   Du,J., Chen,T., Zou,X., Xiong,B. and Lu,G.
  TITLE     Dppa2 knockdown-induced differentiation and repressed proliferation
            of mouse embryonic stem cells
  JOURNAL   J Biochem 147 (2), 265-271 (2010)
   PUBMED   19846433
  REMARK    GeneRIF: Results showed that the expression of Dppa2 decreased
            markedly in differentiated cells. Dppa2 might play a role in
            maintenance of the undifferentiated state and proliferation of ES
            cells
            Erratum:[J Biochem. 2010 Jun;147(6):929]
REFERENCE   8  (bases 1 to 1941)
  AUTHORS   Maldonado-Saldivia,J., van den Bergen,J., Krouskos,M.,
            Gilchrist,M., Lee,C., Li,R., Sinclair,A.H., Surani,M.A. and
            Western,P.S.
  TITLE     Dppa2 and Dppa4 are closely linked SAP motif genes restricted to
            pluripotent cells and the germ line
  JOURNAL   Stem Cells 25 (1), 19-28 (2007)
   PUBMED   16990585
  REMARK    GeneRIF: Study of expression and function of pluripotent markers
            such as Dppa2 and Dppa4 is likely to unveil new aspects of the
            regulation of pluripotency and germ line development in mammals.
REFERENCE   9  (bases 1 to 1941)
  AUTHORS   Du,J., Lin,G., Nie,Z.Y. and Lu,G.X.
  TITLE     [Molecular cloning and characterization analysis of HPESCRG1, a
            novel gene expressed specifically in human embryonic stem cell]
  JOURNAL   Zhonghua Yi Xue Yi Chuan Xue Za Zhi 21 (6), 542-547 (2004)
   PUBMED   15583978
REFERENCE   10 (bases 1 to 1941)
  AUTHORS   Bortvin,A., Eggan,K., Skaletsky,H., Akutsu,H., Berry,D.L.,
            Yanagimachi,R., Page,D.C. and Jaenisch,R.
  TITLE     Incomplete reactivation of Oct4-related genes in mouse embryos
            cloned from somatic nuclei
  JOURNAL   Development 130 (8), 1673-1680 (2003)
   PUBMED   12620990
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AY561246.1.
            
            On or before Jan 24, 2005 this sequence version replaced
            XM_358869.2, XM_129276.4, XM_489583.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY561246.1, AK145645.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164134 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1941
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="16"
                     /map="16 30.75 cM"
     gene            1..1941
                     /gene="Dppa2"
                     /gene_synonym="2410088E07Rik; D19Mgi18; ECAT15-2"
                     /note="developmental pluripotency associated 2"
                     /db_xref="GeneID:73703"
                     /db_xref="MGI:MGI:2157523"
     exon            1..266
                     /gene="Dppa2"
                     /gene_synonym="2410088E07Rik; D19Mgi18; ECAT15-2"
                     /inference="alignment:Splign:2.1.0"
     exon            267..402
                     /gene="Dppa2"
                     /gene_synonym="2410088E07Rik; D19Mgi18; ECAT15-2"
                     /inference="alignment:Splign:2.1.0"
     exon            403..554
                     /gene="Dppa2"
                     /gene_synonym="2410088E07Rik; D19Mgi18; ECAT15-2"
                     /inference="alignment:Splign:2.1.0"
     exon            555..608
                     /gene="Dppa2"
                     /gene_synonym="2410088E07Rik; D19Mgi18; ECAT15-2"
                     /inference="alignment:Splign:2.1.0"
     exon            609..864
                     /gene="Dppa2"
                     /gene_synonym="2410088E07Rik; D19Mgi18; ECAT15-2"
                     /inference="alignment:Splign:2.1.0"
     exon            865..1060
                     /gene="Dppa2"
                     /gene_synonym="2410088E07Rik; D19Mgi18; ECAT15-2"
                     /inference="alignment:Splign:2.1.0"
     exon            1061..1941
                     /gene="Dppa2"
                     /gene_synonym="2410088E07Rik; D19Mgi18; ECAT15-2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aaggagaagg tgtggctggc ttttgattta cttaagaact cagctttttg ctatcaatta
       61 tctactgaga cccagagaac tgataaaatc acgtcaaaga gaagagggtg gagagaggag
      121 gagggggaag agcttaattg ggccacagga agacaggaag cagtcattta cttataaaag
      181 aagtcggcat tcattcagcg gctgcctttg tcttcttcca agcctgcctg aaaatgtcat
      241 acttcggcct ggagactttc aacgagaacc aatctgagga aaacttggat gaagaaagtg
      301 tgattttaac gctggtcccc tttaaggagg aggaggagcc aaacacagac tacgctacgc
      361 aatcaaatgt ttcttcttca accttagacc acacaccacc agcccgttct ctggtgaggc
      421 atgctggaat caaacaccca accagaacca taccaagcac ctgtcctccg cccagcctgc
      481 ctcctattag ggacgtgtcc cggaacactc ttcgggagtg gtgtcggtat cataacttga
      541 gtacggatgg caagaaagtt gaggtctatt tgagacttcg gagacactcc tattctaaac
      601 aagaatgtta tattcccaat acatctcggg aggccagaat gaagcagggt cccaagaaat
      661 ccaagatagt cttcagagga atcgggcctc caagcgggtg ccaaaggaaa aaggaggaga
      721 gtggtgtcct ggaaattcta acttcaccta aggagtccac atttgcagcc tgggcaagga
      781 ttgccatgag agcagctcag tcaatgtcta agaatcgatg tcctcttccg tctaatgtgg
      841 aggcctttct gccacaagcc actggatcca gatggtgtgt tgtccatggc aggcagctcc
      901 ctgcagataa gaaaggttgg gttcgcctgc aatttcttgc tggacagacc tgggttccag
      961 acactcccca aaggatgaat tttctcttcc tgttaccggc ctgtattatc ccagaaccag
     1021 gagtggaaga taatttgcta tgtcctgaat gtgttcacag caacaagaag atcctaagaa
     1081 actttaaaat tagaagccgt gcaaagaaaa atgccctacc cccaaatatg ccgccgtaga
     1141 caagatttta ctctgatcta aagggaatgg aagaatattc tgtgatccct ataatggcta
     1201 aaaacaaaca aaacaaaaca aacaaacaaa aacctggctg tcagtcatca gaagcccctc
     1261 ctcctgtctc ccagcagagt ggagactctg ttgacaaatc agcatccatc tctctaacaa
     1321 cagcccgttg cattttaaca tctctgactg acagctcctc atggcctcgt gctggatttg
     1381 catcactcta acaacacctc gctgtatctt aacatctctg acagctcctc atggcctcgt
     1441 gctggattgg ctaaatgctt agctacctga gaaatgattc ggttttactg ggtttgtttt
     1501 gctgtacttt ttttatataa attttttttt ggagggggga gatggggagc agtttcaaat
     1561 tagcaaagca gaaagtactt tttttaaaaa tatatataat tttttttgag tatggcttta
     1621 tcatgtagca actccagtgg acctggaaat tctaggtaga ccagacacgt gttgggtttt
     1681 acatgcctgt acaataccac ttagccagta ctgatgtatg tttgactagt atagagttca
     1741 ttgcttgtgc taaacaacct gggtgttgac aagtgtttat agagtgccat acatttgaaa
     1801 tcatatagta tgctaccgtt cagattggct tttacctagc aatatgcctg tgagaaatat
     1861 ccatgtcctc gattgatttt tcttaatgtt gagattccat tgtccaagat gtgccttatg
     1921 aattgatgct attacatatg g
//
