LOCUS       NM_026767                506 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus dolichyl-phosphate mannosyltransferase polypeptide 3
            (Dpm3), mRNA.
ACCESSION   NM_026767 XM_130951
VERSION     NM_026767.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 506)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 506)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   3  (bases 1 to 506)
  AUTHORS   Roma,G., Cobellis,G., Claudiani,P., Maione,F., Cruz,P., Tripoli,G.,
            Sardiello,M., Peluso,I. and Stupka,E.
  TITLE     A novel view of the transcriptome revealed from gene trapping in
            mouse embryonic stem cells
  JOURNAL   Genome Res 17 (7), 1051-1060 (2007)
   PUBMED   17540781
REFERENCE   4  (bases 1 to 506)
  AUTHORS   Blackshaw,S., Harpavat,S., Trimarchi,J., Cai,L., Huang,H.,
            Kuo,W.P., Weber,G., Lee,K., Fraioli,R.E., Cho,S.H., Yung,R.,
            Asch,E., Ohno-Machado,L., Wong,W.H. and Cepko,C.L.
  TITLE     Genomic analysis of mouse retinal development
  JOURNAL   PLoS Biol 2 (9), E247 (2004)
   PUBMED   15226823
REFERENCE   5  (bases 1 to 506)
  AUTHORS   Maeda,Y., Tanaka,S., Hino,J., Kangawa,K. and Kinoshita,T.
  TITLE     Human dolichol-phosphate-mannose synthase consists of three
            subunits, DPM1, DPM2 and DPM3
  JOURNAL   EMBO J 19 (11), 2475-2482 (2000)
   PUBMED   10835346
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CJ237809.1, AK003223.1 and AI527477.1.
            
            On Aug 15, 2013 this sequence version replaced NM_026767.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CJ237809.1, BE446919.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-91                CJ237809.1         1-91
            92-495              AK003223.1         2-405
            496-506             AI527477.1         440-450
FEATURES             Location/Qualifiers
     source          1..506
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 39.03 cM"
     gene            1..506
                     /gene="Dpm3"
                     /gene_synonym="1110001H19Rik"
                     /note="dolichyl-phosphate mannosyltransferase polypeptide
                     3"
                     /db_xref="GeneID:68563"
                     /db_xref="MGI:MGI:1915813"
     exon            1..146
                     /gene="Dpm3"
                     /gene_synonym="1110001H19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            147..497
                     /gene="Dpm3"
                     /gene_synonym="1110001H19Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             152..430
                     /gene="Dpm3"
                     /gene_synonym="1110001H19Rik"
                     /EC_number="2.4.1.83"
                     /note="MPD synthase subunit 3; DPM synthase complex
                     subunit 3; mannose-P-dolichol synthase subunit 3;
                     dolichol-phosphate mannose synthase subunit 3;
                     dolichyl-phosphate beta-D-mannosyltransferase subunit 3;
                     DPM synthase subunit 3"
                     /codon_start=1
                     /product="dolichol-phosphate mannosyltransferase subunit
                     3"
                     /protein_id="NP_081043.1"
                     /db_xref="CCDS:CCDS38487.1"
                     /db_xref="GeneID:68563"
                     /db_xref="MGI:MGI:1915813"
                     /translation="MTKLTQWLWGLALLGSAWAALTMGALGLELPFPCREVLWPLPAY
                     LLVSAGCYALGTVGYRVATFHDCEDAARELQSQIVEARADLARRGLRF"
     regulatory      473..478
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Dpm3"
                     /gene_synonym="1110001H19Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      497
                     /gene="Dpm3"
                     /gene_synonym="1110001H19Rik"
                     /note="major polyA site"
ORIGIN      
        1 aagagcagtg tataaccaac ctggatctga gcgcggccga aattgtccta agaactacag
       61 ttcccagaag gcagcccgga aaaagggcgg tagtagaaag ggacttccgg atgctgatgc
      121 gggccttgtc agcgcggcac acggagccaa catgacgaag ttaacacagt ggctttgggg
      181 actggctctc ctgggctctg cctgggctgc cctgaccatg ggagcactgg gcttggagtt
      241 gcctttcccc tgccgagagg tcctgtggcc actgcctgcc tacctgttgg tctccgctgg
      301 ctgctatgcc ctgggcacgg tgggctatcg cgtagctaca tttcacgact gcgaggacgc
      361 tgcccgagag ctgcagagcc agatcgtgga ggcccgagct gatttagcac gcagggggct
      421 gcgcttctga cacctaaacc cattccagtc tggacatctt tcctcattcc gcattaaaat
      481 gcagttttat tttctaaaaa aaaaaa
//
