LOCUS       NP_001254554             378 aa            linear   ROD 27-APR-2025
DEFINITION  zinc finger protein DPF3 isoform 1 [Mus musculus].
ACCESSION   NP_001254554
VERSION     NP_001254554.1
DBSOURCE    REFSEQ: accession NM_001267625.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (residues 1 to 378)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (residues 1 to 378)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   3  (residues 1 to 378)
  AUTHORS   He,Y., Chen,Q., Dai,J., Cui,Y., Zhang,C., Wen,X., Li,J., Xiao,Y.,
            Peng,X., Liu,M., Shen,B., Sha,J., Hu,Z., Li,J. and Shu,W.
  TITLE     Single-cell RNA-Seq reveals a highly coordinated transcriptional
            program in mouse germ cells during primordial follicle formation
  JOURNAL   Aging Cell 20 (7), e13424 (2021)
   PUBMED   34174788
REFERENCE   4  (residues 1 to 378)
  AUTHORS   Basta,J.M., Singh,A.P., Robbins,L., Stout,L., Pherson,M. and
            Rauchman,M.
  TITLE     The core SWI/SNF catalytic subunit Brg1 regulates nephron
            progenitor cell proliferation and differentiation
  JOURNAL   Dev Biol 464 (2), 176-187 (2020)
   PUBMED   32504627
REFERENCE   5  (residues 1 to 378)
  AUTHORS   Zhu,X., Lan,B., Yi,X., He,C., Dang,L., Zhou,X., Lu,Y., Sun,Y.,
            Liu,Z., Bai,X., Zhang,K., Li,B., Li,M.J., Chen,Y. and Zhang,L.
  TITLE     HRP2-DPF3a-BAF complex coordinates histone modification and
            chromatin remodeling to regulate myogenic gene transcription
  JOURNAL   Nucleic Acids Res 48 (12), 6563-6582 (2020)
   PUBMED   32459350
  REMARK    GeneRIF: HRP2-DPF3a-BAF complex coordinates histone modification
            and chromatin remodeling to regulate myogenic gene transcription.
REFERENCE   6  (residues 1 to 378)
  AUTHORS   de la Serna,I.L., Carlson,K.A. and Imbalzano,A.N.
  TITLE     Mammalian SWI/SNF complexes promote MyoD-mediated muscle
            differentiation
  JOURNAL   Nat Genet 27 (2), 187-190 (2001)
   PUBMED   11175787
REFERENCE   7  (residues 1 to 378)
  AUTHORS   Zhang,H.S., Gavin,M., Dahiya,A., Postigo,A.A., Ma,D., Luo,R.X.,
            Harbour,J.W. and Dean,D.C.
  TITLE     Exit from G1 and S phase of the cell cycle is regulated by
            repressor complexes containing HDAC-Rb-hSWI/SNF and Rb-hSWI/SNF
  JOURNAL   Cell 101 (1), 79-89 (2000)
   PUBMED   10778858
REFERENCE   8  (residues 1 to 378)
  AUTHORS   Phelan,M.L., Sif,S., Narlikar,G.J. and Kingston,R.E.
  TITLE     Reconstitution of a core chromatin remodeling complex from SWI/SNF
            subunits
  JOURNAL   Mol Cell 3 (2), 247-253 (1999)
   PUBMED   10078207
REFERENCE   9  (residues 1 to 378)
  AUTHORS   Wang,W., Xue,Y., Zhou,S., Kuo,A., Cairns,B.R. and Crabtree,G.R.
  TITLE     Diversity and specialization of mammalian SWI/SNF complexes
  JOURNAL   Genes Dev 10 (17), 2117-2130 (1996)
   PUBMED   8804307
REFERENCE   10 (residues 1 to 378)
  AUTHORS   Chestkov,A.V., Baka,I.D., Kost,M.V., Georgiev,G.P. and Buchman,V.L.
  TITLE     The d4 gene family in the human genome
  JOURNAL   Genomics 36 (1), 174-177 (1996)
   PUBMED   8812431
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK012970.1 and AK039011.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK039011.1, SRR7345562.1296020.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..378
                     /organism="Mus musculus"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="12"
                     /map="12 38.64 cM"
     Protein         1..378
                     /product="zinc finger protein DPF3 isoform 1"
                     /note="cerebellum D4; zinc finger protein DPF3; D4 zinc
                     and double PHD finger family 3; BRG1-associated factor
                     45C; zinc finger protein cer-d4"
                     /calculated_mol_wt=42939
     Region          13..79
                     /region_name="DPF1-3_N"
                     /note="DPF1-3, N-terminal; pfam14051"
                     /db_xref="CDD:464074"
     Region          146..193
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (P58269.2)"
     Region          <195..222
                     /region_name="SFP1"
                     /note="Putative transcriptional repressor regulating G2/M
                     transition [Transcription / Cell division and chromosome
                     partitioning]; COG5189"
                     /db_xref="CDD:227516"
     Region          225..254
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (P58269.2)"
     Region          261..317
                     /region_name="PHD1_DPF3"
                     /note="PHD finger 1 found in D4, zinc and double PHD
                     fingers family 3 (DPF3); cd15692"
                     /db_xref="CDD:277162"
     Site            order(261,263..264,266,284,289..291,296..298,302,311,
                     313..315)
                     /site_type="other"
                     /note="histone H3 binding site [polypeptide binding]"
                     /db_xref="CDD:277162"
     Site            order(298..299,301..302,305..306,309,311..312,314,316)
                     /site_type="other"
                     /note="PHD2 interface [polypeptide binding]"
                     /db_xref="CDD:277162"
     Region          317..332
                     /region_name="Interaction with HDGFL2.
                     /evidence=ECO:0000250|UniProtKB:Q92784"
                     /note="propagated from UniProtKB/Swiss-Prot (P58269.2)"
     Region          318..363
                     /region_name="PHD2_d4"
                     /note="PHD finger 2 found in d4 gene family proteins;
                     cd15530"
                     /db_xref="CDD:277005"
     Site            order(318,333..339)
                     /site_type="other"
                     /note="PHD1 interface [polypeptide binding]"
                     /db_xref="CDD:277005"
     Site            323
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q92784; propagated from
                     UniProtKB/Swiss-Prot (P58269.2)"
     Site            order(325,328..335,343,353..358)
                     /site_type="other"
                     /note="histone H3 binding site [polypeptide binding]"
                     /db_xref="CDD:277005"
     CDS             1..378
                     /gene="Dpf3"
                     /gene_synonym="2810403B03Rik; 6530402L11Rik; BAF45C;
                     cer-d4; CERD4; Gm18872"
                     /coded_by="NM_001267625.1:29..1165"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /db_xref="CCDS:CCDS59574.1"
                     /db_xref="GeneID:70127"
                     /db_xref="MGI:MGI:1917377"
ORIGIN      
        1 matvihnplk algdqfykea iehcrsynsr lcaersvrlp fldsqtgvaq nncyiwmekr
       61 hrgpglapgq lytyparcwr kkrrlhpped pklrlleikp evelplkkdg ftsesttlea
      121 llrgegvekk vdareeesiq eiqrvlende nveegneeed leedvpkrkn rtrgrargsa
      181 ggrrrhdaas qedhdkpyvc dicgkryknr pglsyhyaht hlaseegdea qdqetrsppn
      241 hrnenhrpqk gpdgtvipnn ycdfclggsn mnkksgrpee lvscadcgrs ghptclqftl
      301 nmteavktyk wqciecksci lcgtsenddq llfcddcdrg yhmyclnppv aeppegswsc
      361 hlcwellkek asafgcqa
//
