LOCUS       NM_172803               8072 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus dedicator of cytokinesis 4 (Dock4), mRNA.
ACCESSION   NM_172803 XM_358307
VERSION     NM_172803.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 8072)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 8072)
  AUTHORS   Guo,D., Yang,X., Gao,M., Chen,X., Tang,Y., Shen,L., Li,K. and
            Shi,L.
  TITLE     Deficiency of Autism-Related Gene Dock4 Leads to Impaired Spatial
            Memory and Hippocampal Function in Mice at Late Middle Age
  JOURNAL   Cell Mol Neurobiol 43 (3), 1129-1146 (2023)
   PUBMED   35635601
  REMARK    GeneRIF: Deficiency of Autism-Related Gene Dock4 Leads to Impaired
            Spatial Memory and Hippocampal Function in Mice at Late Middle Age.
REFERENCE   3  (bases 1 to 8072)
  AUTHORS   Yazbeck,P., Cullere,X., Bennett,P., Yajnik,V., Wang,H., Kawada,K.,
            Davis,V.M., Parikh,A., Kuo,A., Mysore,V., Hla,T., Milstone,D.S. and
            Mayadas,T.N.
  TITLE     DOCK4 Regulation of Rho GTPases Mediates Pulmonary Vascular Barrier
            Function
  JOURNAL   Arterioscler Thromb Vasc Biol 42 (7), 886-902 (2022)
   PUBMED   35477279
  REMARK    GeneRIF: DOCK4 Regulation of Rho GTPases Mediates Pulmonary
            Vascular Barrier Function.
REFERENCE   4  (bases 1 to 8072)
  AUTHORS   Huang,Y., Yang,Y., Zhao,Y., Guo,D., Chen,L., Shi,L. and Xu,G.
  TITLE     DOCK4 regulates ghrelin production in gastric X/A-like cells
  JOURNAL   J Endocrinol Invest 45 (7), 1447-1454 (2022)
   PUBMED   35302184
  REMARK    GeneRIF: DOCK4 regulates ghrelin production in gastric X/A-like
            cells.
REFERENCE   5  (bases 1 to 8072)
  AUTHORS   Yang,X., Guo,D., Li,K. and Shi,L.
  TITLE     Altered postnatal developmental patterns of ultrasonic
            vocalizations in Dock4 knockout mice
  JOURNAL   Behav Brain Res 406, 113232 (2021)
   PUBMED   33705839
  REMARK    GeneRIF: Altered postnatal developmental patterns of ultrasonic
            vocalizations in Dock4 knockout mice.
REFERENCE   6  (bases 1 to 8072)
  AUTHORS   Davis,R.C., Schadt,E.E., Cervino,A.C., Peterfy,M. and Lusis,A.J.
  TITLE     Ultrafine mapping of SNPs from mouse strains C57BL/6J, DBA/2J, and
            C57BLKS/J for loci contributing to diabetes and atherosclerosis
            susceptibility
  JOURNAL   Diabetes 54 (4), 1191-1199 (2005)
   PUBMED   15793261
REFERENCE   7  (bases 1 to 8072)
  AUTHORS   Yajnik,V., Paulding,C., Sordella,R., McClatchey,A.I., Saito,M.,
            Wahrer,D.C., Reynolds,P., Bell,D.W., Lake,R., van den Heuvel,S.,
            Settleman,J. and Haber,D.A.
  TITLE     DOCK4, a GTPase activator, is disrupted during tumorigenesis
  JOURNAL   Cell 112 (5), 673-684 (2003)
   PUBMED   12628187
REFERENCE   8  (bases 1 to 8072)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Aizawa,H., Yuasa,S.,
            Nakajima,D., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: II. The complete nucleotide sequences of 400 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (1), 35-48 (2003)
   PUBMED   12693553
REFERENCE   9  (bases 1 to 8072)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   10 (bases 1 to 8072)
  AUTHORS   Thomas,J.W., Summers,T.J., Lee-Lin,S.Q., Maduro,V.V., Idol,J.R.,
            Mastrian,S.D., Ryan,J.F., Jamison,D.C. and Green,E.D.
  TITLE     Comparative genome mapping in the sequence-based era: early
            experience with human chromosome 7
  JOURNAL   Genome Res 10 (5), 624-633 (2000)
   PUBMED   10810084
  REMARK    Review article
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BB641326.1, AK122353.1 and CAAA01013241.1.
            
            On or before May 17, 2005 this sequence version replaced
            XM_358307.3, NM_172803.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK122353.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164132
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-653               BB641326.1         2-654
            654-6412            AK122353.1         636-6394
            6413-8072           CAAA01013241.1     30855-32514         c
FEATURES             Location/Qualifiers
     source          1..8072
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="12"
                     /map="12 18.06 cM"
     gene            1..8072
                     /gene="Dock4"
                     /gene_synonym="5330406C03; 6330411N01Rik; C030023J22;
                     mKIAA0716"
                     /note="dedicator of cytokinesis 4"
                     /db_xref="GeneID:238130"
                     /db_xref="MGI:MGI:1918006"
     exon            1..342
                     /gene="Dock4"
                     /gene_synonym="5330406C03; 6330411N01Rik; C030023J22;
                     mKIAA0716"
                     /inference="alignment:Splign:2.1.0"
     CDS             306..6242
                     /gene="Dock4"
                     /gene_synonym="5330406C03; 6330411N01Rik; C030023J22;
                     mKIAA0716"
                     /codon_start=1
                     /product="dedicator of cytokinesis protein 4"
                     /protein_id="NP_766391.2"
                     /db_xref="CCDS:CCDS25895.1"
                     /db_xref="GeneID:238130"
                     /db_xref="MGI:MGI:1918006"
                     /translation="MWIPTEHEKYGVVIASFRGTVPYGLSLEIGDTVQILEKCDGWYR
                     GFALKNPNIKGIFPSSYVHLKNACVKNKGQFEMVIPTEDSVITEMTSTLRDWGTMWKQ
                     LYVRNEGDLFHRLWHIMNEILDLRRQVLVGHLTHDRMKDVKRHITARLDWGNEQLGLD
                     LVPRKEYAMVDPEDISITELYRLMEHRHRKKDTPVQASSHHLFVQMKSLMCSNLGEEL
                     EVIFSLFDSKENRPISERFFLRLNRNGLPKAPDKPERHCSLFVDLGSSELRKDIYITV
                     HIIRIGRMGAGEKKNACSVQYRRPFGCAVLSIADLLTGETKDDLVLKVYMCNTESEWY
                     QIHENIIKKLNARYNLTGSNAGLAVSLQLLHGDIEQIRREYSSVFSHGVSITRKLGFS
                     DIIMPGEMRNDLYITVERGEFEKGGKSVARNVEVTMFIVDSNGQPLKDFISFGSGEPP
                     ASEYHSFVLYHNNSPRWSELLKLPIPVDKFRGSHIRFEFRHCSTKEKGEKKLFGFSFV
                     PLMQEDGRTLPDGTHELIVHKCEENTNLQDTTRYLKLPFSKVIFLGNNNQTMKATKES
                     FWITSFLCSTKLTQNGDMLDLLKWRTHPDKITGCLSKLKEIDGSEIVKFLQDTLDTLF
                     GILDENSQKYGSKVFDSLVHIINLLQDSKFHHFKPVMDTYIESHFAGALAYRDLIKVL
                     KWYVDRITEAERQEHIQEVLKAQEYIFKYIVQSRRLFSLATGGQNEEEFRCCIQELLM
                     SVRFFLSQESKGTGALSQSQAVFLSSFPAVYSELLKLFDVREVANLVQDTLGSLPTIM
                     HVDDSLQAIKLQCIGKTVESQLYTNPDSRYILLPVVLHHLHIHLQEQKDLIMCARILS
                     NVFCLIKKNSSEKSVLEEIDVIVASLLDILLRTILEITSRPQASSSAMRLQFQDVTGE
                     FVACLLSLLRQMTDRHYQQLLNSFSTKEELRDFLLQIFTVFRILIRPEMFPKDWTVMR
                     LVANNVIITTVLYLSDALRKNFLNENFDYKIWDSYFYLAVIFINQLCLQLEMFTPSKK
                     KKVLEKYGDMRVTMGCEIFSMWQNLGEHKLHFIPALIGPFLEVTLIPQPDLRNVMIPI
                     FHDMMDWEQRRSGNFKQVEAKLIDKLDSLMSEGKGDETYRELFNSIIPLFGPYPSLLK
                     KIERETWRESGVSLIATVTRLMERLLDYRDCMKIGEVDGKKIGCTVSLLNFYKTELNK
                     EEMYIRYIHKLYDLHLKAQNFTEAAYTLLLYDELLEWSDRPLREFLTYPMQTEWQRKE
                     HLHLTIIQNFDRGKCWENGIILCRKIAEQYESYYDYRNLSKMRMMEASLYDKIMDQQR
                     LEPEFFRVGFYGKKFPFFLRNKEFVCRGHDYERLEAFQQRMLNEFPHAIAMQHANQPD
                     ETIFQAEAQYLQIYAVTPIPESQEVLQREGVPDNIKSFYKVNHIWKFRYDRPFHKGAK
                     DKENEFKSLWVERTSLYLVQSLPGISRWFEVEKREVVEMSPLENAIEVLENKNQQLKT
                     LISQCQTRQMQNINPLTMCLNGVIDAAVNGGVSRYQEAFFVKDYILSHPEDGEKIARL
                     RELMLEQAQILEFGLAVHEKFVPQDMRPLHKKLVDQFFVMKSSFGIQEFPACIQASPV
                     HFPNGSPRVCRNSAPASMSPDGTRVIPRRSPLSYPAVNRYSSSSLSSQASAEVSNITG
                     QSESSDEVFNMQPSPSTSSLSSTHSASPNVTSSAPSSARASPLLSDKHKHSRENSCLS
                     PRDRPCSAIYPTPVEPSQRMLFNHIGDGALPRSDPNLSAPEKAVNPTPSSWSLDSGKE
                     AKNMSDSGKLISPPVPPRPTQTASPARHTTSVSPSPAGRSPLKGSVQSFTPSPVEYNS
                     PGLSSNSPVLSGSYSSGISSLSRCSTSETSGFENQANEQSVPVPVPVPVPVPVPSFSG
                     SEEPVRKESKTPPPYSVYERTLRRPVPLPHSLSIPVTSEPPALPPKPLAARSSHLENG
                     TRRTEPGPRPRPLPRKVSQL"
     exon            343..426
                     /gene="Dock4"
                     /gene_synonym="5330406C03; 6330411N01Rik; C030023J22;
                     mKIAA0716"
                     /inference="alignment:Splign:2.1.0"
     exon            427..467
                     /gene="Dock4"
                     /gene_synonym="5330406C03; 6330411N01Rik; C030023J22;
                     mKIAA0716"
                     /inference="alignment:Splign:2.1.0"
     exon            468..523
                     /gene="Dock4"
                     /gene_synonym="5330406C03; 6330411N01Rik; C030023J22;
                     mKIAA0716"
                     /inference="alignment:Splign:2.1.0"
     exon            524..620
                     /gene="Dock4"
                     /gene_synonym="5330406C03; 6330411N01Rik; C030023J22;
                     mKIAA0716"
                     /inference="alignment:Splign:2.1.0"
     exon            621..769
                     /gene="Dock4"
                     /gene_synonym="5330406C03; 6330411N01Rik; C030023J22;
                     mKIAA0716"
                     /inference="alignment:Splign:2.1.0"
     exon            770..854
                     /gene="Dock4"
                     /gene_synonym="5330406C03; 6330411N01Rik; C030023J22;
                     mKIAA0716"
                     /inference="alignment:Splign:2.1.0"
     exon            855..1006
                     /gene="Dock4"
                     /gene_synonym="5330406C03; 6330411N01Rik; C030023J22;
                     mKIAA0716"
                     /inference="alignment:Splign:2.1.0"
     exon            1007..1088
                     /gene="Dock4"
                     /gene_synonym="5330406C03; 6330411N01Rik; C030023J22;
                     mKIAA0716"
                     /inference="alignment:Splign:2.1.0"
     exon            1089..1149
                     /gene="Dock4"
                     /gene_synonym="5330406C03; 6330411N01Rik; C030023J22;
                     mKIAA0716"
                     /inference="alignment:Splign:2.1.0"
     exon            1150..1282
                     /gene="Dock4"
                     /gene_synonym="5330406C03; 6330411N01Rik; C030023J22;
                     mKIAA0716"
                     /inference="alignment:Splign:2.1.0"
     exon            1283..1371
                     /gene="Dock4"
                     /gene_synonym="5330406C03; 6330411N01Rik; C030023J22;
                     mKIAA0716"
                     /inference="alignment:Splign:2.1.0"
     exon            1372..1497
                     /gene="Dock4"
                     /gene_synonym="5330406C03; 6330411N01Rik; C030023J22;
                     mKIAA0716"
                     /inference="alignment:Splign:2.1.0"
     exon            1498..1622
                     /gene="Dock4"
                     /gene_synonym="5330406C03; 6330411N01Rik; C030023J22;
                     mKIAA0716"
                     /inference="alignment:Splign:2.1.0"
     exon            1623..1785
                     /gene="Dock4"
                     /gene_synonym="5330406C03; 6330411N01Rik; C030023J22;
                     mKIAA0716"
                     /inference="alignment:Splign:2.1.0"
     exon            1786..1892
                     /gene="Dock4"
                     /gene_synonym="5330406C03; 6330411N01Rik; C030023J22;
                     mKIAA0716"
                     /inference="alignment:Splign:2.1.0"
     exon            1893..2049
                     /gene="Dock4"
                     /gene_synonym="5330406C03; 6330411N01Rik; C030023J22;
                     mKIAA0716"
                     /inference="alignment:Splign:2.1.0"
     exon            2050..2147
                     /gene="Dock4"
                     /gene_synonym="5330406C03; 6330411N01Rik; C030023J22;
                     mKIAA0716"
                     /inference="alignment:Splign:2.1.0"
     exon            2148..2231
                     /gene="Dock4"
                     /gene_synonym="5330406C03; 6330411N01Rik; C030023J22;
                     mKIAA0716"
                     /inference="alignment:Splign:2.1.0"
     exon            2232..2332
                     /gene="Dock4"
                     /gene_synonym="5330406C03; 6330411N01Rik; C030023J22;
                     mKIAA0716"
                     /inference="alignment:Splign:2.1.0"
     exon            2333..2414
                     /gene="Dock4"
                     /gene_synonym="5330406C03; 6330411N01Rik; C030023J22;
                     mKIAA0716"
                     /inference="alignment:Splign:2.1.0"
     exon            2415..2585
                     /gene="Dock4"
                     /gene_synonym="5330406C03; 6330411N01Rik; C030023J22;
                     mKIAA0716"
                     /inference="alignment:Splign:2.1.0"
     exon            2586..2778
                     /gene="Dock4"
                     /gene_synonym="5330406C03; 6330411N01Rik; C030023J22;
                     mKIAA0716"
                     /inference="alignment:Splign:2.1.0"
     exon            2779..2906
                     /gene="Dock4"
                     /gene_synonym="5330406C03; 6330411N01Rik; C030023J22;
                     mKIAA0716"
                     /inference="alignment:Splign:2.1.0"
     exon            2907..3041
                     /gene="Dock4"
                     /gene_synonym="5330406C03; 6330411N01Rik; C030023J22;
                     mKIAA0716"
                     /inference="alignment:Splign:2.1.0"
     exon            3042..3140
                     /gene="Dock4"
                     /gene_synonym="5330406C03; 6330411N01Rik; C030023J22;
                     mKIAA0716"
                     /inference="alignment:Splign:2.1.0"
     exon            3141..3235
                     /gene="Dock4"
                     /gene_synonym="5330406C03; 6330411N01Rik; C030023J22;
                     mKIAA0716"
                     /inference="alignment:Splign:2.1.0"
     exon            3236..3311
                     /gene="Dock4"
                     /gene_synonym="5330406C03; 6330411N01Rik; C030023J22;
                     mKIAA0716"
                     /inference="alignment:Splign:2.1.0"
     exon            3312..3412
                     /gene="Dock4"
                     /gene_synonym="5330406C03; 6330411N01Rik; C030023J22;
                     mKIAA0716"
                     /inference="alignment:Splign:2.1.0"
     exon            3413..3471
                     /gene="Dock4"
                     /gene_synonym="5330406C03; 6330411N01Rik; C030023J22;
                     mKIAA0716"
                     /inference="alignment:Splign:2.1.0"
     exon            3472..3620
                     /gene="Dock4"
                     /gene_synonym="5330406C03; 6330411N01Rik; C030023J22;
                     mKIAA0716"
                     /inference="alignment:Splign:2.1.0"
     exon            3621..3706
                     /gene="Dock4"
                     /gene_synonym="5330406C03; 6330411N01Rik; C030023J22;
                     mKIAA0716"
                     /inference="alignment:Splign:2.1.0"
     exon            3707..3733
                     /gene="Dock4"
                     /gene_synonym="5330406C03; 6330411N01Rik; C030023J22;
                     mKIAA0716"
                     /inference="alignment:Splign:2.1.0"
     exon            3734..3829
                     /gene="Dock4"
                     /gene_synonym="5330406C03; 6330411N01Rik; C030023J22;
                     mKIAA0716"
                     /inference="alignment:Splign:2.1.0"
     exon            3830..3890
                     /gene="Dock4"
                     /gene_synonym="5330406C03; 6330411N01Rik; C030023J22;
                     mKIAA0716"
                     /inference="alignment:Splign:2.1.0"
     exon            3891..3984
                     /gene="Dock4"
                     /gene_synonym="5330406C03; 6330411N01Rik; C030023J22;
                     mKIAA0716"
                     /inference="alignment:Splign:2.1.0"
     exon            3985..4133
                     /gene="Dock4"
                     /gene_synonym="5330406C03; 6330411N01Rik; C030023J22;
                     mKIAA0716"
                     /inference="alignment:Splign:2.1.0"
     exon            4134..4220
                     /gene="Dock4"
                     /gene_synonym="5330406C03; 6330411N01Rik; C030023J22;
                     mKIAA0716"
                     /inference="alignment:Splign:2.1.0"
     exon            4221..4325
                     /gene="Dock4"
                     /gene_synonym="5330406C03; 6330411N01Rik; C030023J22;
                     mKIAA0716"
                     /inference="alignment:Splign:2.1.0"
     exon            4326..4467
                     /gene="Dock4"
                     /gene_synonym="5330406C03; 6330411N01Rik; C030023J22;
                     mKIAA0716"
                     /inference="alignment:Splign:2.1.0"
     exon            4468..4634
                     /gene="Dock4"
                     /gene_synonym="5330406C03; 6330411N01Rik; C030023J22;
                     mKIAA0716"
                     /inference="alignment:Splign:2.1.0"
     exon            4635..4721
                     /gene="Dock4"
                     /gene_synonym="5330406C03; 6330411N01Rik; C030023J22;
                     mKIAA0716"
                     /inference="alignment:Splign:2.1.0"
     exon            4722..4898
                     /gene="Dock4"
                     /gene_synonym="5330406C03; 6330411N01Rik; C030023J22;
                     mKIAA0716"
                     /inference="alignment:Splign:2.1.0"
     exon            4899..4982
                     /gene="Dock4"
                     /gene_synonym="5330406C03; 6330411N01Rik; C030023J22;
                     mKIAA0716"
                     /inference="alignment:Splign:2.1.0"
     exon            4983..5102
                     /gene="Dock4"
                     /gene_synonym="5330406C03; 6330411N01Rik; C030023J22;
                     mKIAA0716"
                     /inference="alignment:Splign:2.1.0"
     exon            5103..5224
                     /gene="Dock4"
                     /gene_synonym="5330406C03; 6330411N01Rik; C030023J22;
                     mKIAA0716"
                     /inference="alignment:Splign:2.1.0"
     exon            5225..5345
                     /gene="Dock4"
                     /gene_synonym="5330406C03; 6330411N01Rik; C030023J22;
                     mKIAA0716"
                     /inference="alignment:Splign:2.1.0"
     exon            5346..5427
                     /gene="Dock4"
                     /gene_synonym="5330406C03; 6330411N01Rik; C030023J22;
                     mKIAA0716"
                     /inference="alignment:Splign:2.1.0"
     exon            5428..5537
                     /gene="Dock4"
                     /gene_synonym="5330406C03; 6330411N01Rik; C030023J22;
                     mKIAA0716"
                     /inference="alignment:Splign:2.1.0"
     exon            5538..5610
                     /gene="Dock4"
                     /gene_synonym="5330406C03; 6330411N01Rik; C030023J22;
                     mKIAA0716"
                     /inference="alignment:Splign:2.1.0"
     exon            5611..5724
                     /gene="Dock4"
                     /gene_synonym="5330406C03; 6330411N01Rik; C030023J22;
                     mKIAA0716"
                     /inference="alignment:Splign:2.1.0"
     exon            5725..5786
                     /gene="Dock4"
                     /gene_synonym="5330406C03; 6330411N01Rik; C030023J22;
                     mKIAA0716"
                     /inference="alignment:Splign:2.1.0"
     exon            5787..8072
                     /gene="Dock4"
                     /gene_synonym="5330406C03; 6330411N01Rik; C030023J22;
                     mKIAA0716"
                     /inference="alignment:Splign:2.1.0"
     regulatory      6452..6457
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Dock4"
                     /gene_synonym="5330406C03; 6330411N01Rik; C030023J22;
                     mKIAA0716"
                     /note="hexamer: ATTAAA"
     polyA_site      6477
                     /gene="Dock4"
                     /gene_synonym="5330406C03; 6330411N01Rik; C030023J22;
                     mKIAA0716"
                     /note="major polyA site"
ORIGIN      
        1 gagtgccccg gcgtgttcgc ttagttcagt gaatcagaac aatgactgcg ccgccgggtc
       61 cccgggagcg cgtcgcaggg ctgtgagcag ccgcggccgg cagagcggcg ggcggctccg
      121 cctcggcggt gtagtgtcag tgccggctcc ggagccccgg gagcagaccc tgcccagcgc
      181 cgcagcccgc gcgatccgct gtgctccagc gacacagctg ctcttcggga gcggtgcatt
      241 gttgtgagcc actggagggg cgcggggatt gcacagcccg gagcccctca acgcccttca
      301 tagccatgtg gatacctacg gagcacgaga aatacggcgt ggttattgcc agctttcgag
      361 gcaccgtccc gtacggcctg tcattggaga tcggagacac tgttcagatc ctggagaagt
      421 gcgacggctg gtacagagga tttgccttaa aaaatcccaa catcaagggt atatttcctt
      481 ccagctatgt tcacttgaaa aatgcctgtg taaagaacaa aggacaattt gaaatggtta
      541 ttcccactga agattctgtt atcaccgaga tgacatcaac tttaagggac tggggaacca
      601 tgtggaaaca gctctatgtc agaaatgaag gggatctctt ccatcgcctg tggcacatca
      661 tgaatgaaat cctcgatctg cgacggcagg tgctagttgg ccatctcacc catgacagga
      721 tgaaggatgt gaagcgccac attactgccc gactggattg gggaaatgaa caactgggac
      781 tagacctggt gcctaggaag gagtacgcaa tggtagaccc agaggacatc agcatcactg
      841 agctgtaccg actgatggaa catcgacatc ggaagaaaga cacccctgtg caggccagca
      901 gtcaccacct ctttgtccag atgaagagcc tcatgtgttc caacctggga gaggagctag
      961 aggtcatctt ctcactcttt gacagcaaag agaatcgccc aatcagtgag agatttttct
     1021 tgagactgaa tagaaatggg cttcccaaag ccccggataa gcctgaaaga cactgttctc
     1081 tctttgtgga cttgggtagc agtgaactca ggaaggacat ctacattacc gtgcacatta
     1141 tccgaattgg tcgaatggga gcaggagaga aaaagaatgc ctgcagtgtt cagtaccggc
     1201 gaccttttgg ctgtgcagtc cttagcattg cagatctcct caccggagag acaaaggatg
     1261 acctggtcct gaaagtgtac atgtgtaata cagagagcga gtggtaccag atccacgaga
     1321 acatcatcaa gaagctgaat gcgcgctata atttgactgg ctccaatgca ggattagcag
     1381 tttccctcca actgttacac ggagacattg aacagatcag aagagaatac tcctcagtgt
     1441 tctctcacgg agtgtccata acgcggaagc tgggtttttc tgacattatc atgcctggtg
     1501 aaatgaggaa tgatttatat atcaccgtag aaagggggga atttgagaaa ggaggcaaga
     1561 gtgtggccag aaatgtggaa gttacaatgt tcattgtaga cagtaatggt cagcccttaa
     1621 aggattttat ctcctttggc tctggagagc caccggctag tgagtaccac tcctttgtgc
     1681 tctatcataa caacagtccc aggtggtcag agctgctgaa acttcctatt cctgtggaca
     1741 aattccgggg ctcccacatc cgctttgagt tccggcattg ttccacaaag gagaaaggag
     1801 aaaagaagtt gttcggtttc tctttcgtgc ccctgatgca agaagacgga aggactctcc
     1861 cagatggcac acacgagctc atcgtgcata agtgtgaaga aaacacaaac cttcaggata
     1921 ctacccgcta cctcaagctc ccattttcca aggtcatctt ccttgggaac aataatcaaa
     1981 ccatgaaggc cacaaaggaa tccttttgga taacatcatt tctctgttcc acaaaactca
     2041 ctcaaaatgg tgatatgctt gatcttttga aatggagaac ccacccagac aagatcacag
     2101 gctgtctctc taagttaaaa gaaatcgatg gctcagagat agtaaagttt ctccaagaca
     2161 cactggatac cttgtttgga atattagatg aaaattccca aaaatatggg tctaaagtgt
     2221 ttgattcttt ggtccacata ataaatttgc tacaagatag caagttccat cattttaagc
     2281 ctgtcatgga cacttacatt gagagtcact ttgctggggc acttgcatac agagatctca
     2341 tcaaagtgct caagtggtac gtggacagga taacggaagc agagcgccag gagcatatcc
     2401 aggaagtgtt gaaggcacaa gagtacattt ttaagtatat agttcaatcc cgaaggctgt
     2461 tttcccttgc caccggaggg cagaatgaag aggaattccg ctgctgcatc caggagctcc
     2521 ttatgtccgt ccgcttcttc ctctcacaag agagcaaagg gactggagct ttatctcagt
     2581 cgcaggctgt gttcttgagc tcctttccag ctgtgtactc agaactgttg aagctctttg
     2641 atgtccggga agtggccaac ttggtccagg acaccctggg cagcctacct accatcatgc
     2701 atgtggacga ttctctgcag gcaattaagc ttcagtgcat tggcaaaact gtcgagagcc
     2761 agctctatac caacccagac tcgcggtaca ttctcctgcc tgtcgtactg catcacctcc
     2821 acatccactt gcaagaacag aaggacttga tcatgtgtgc acgtatcctt agcaacgtgt
     2881 tctgtctcat caagaaaaat agctcagaaa agtctgtgct ggaggaaata gacgtgatag
     2941 tggccagctt gctggatatc ctgctcagga ccatattgga gatcactagt cggcctcaag
     3001 catccagctc cgccatgagg ctgcagttcc aggatgtcac tggggaattt gttgcctgtc
     3061 tcctttccct attacgacaa atgacagata gacattatca gcaacttctg aatagtttca
     3121 gtactaaaga ggagctgagg gatttcttgc tgcagatttt taccgttttc cgaatattga
     3181 tacgcccaga gatgtttccc aaggactgga ctgtcatgcg cctggttgct aacaatgtta
     3241 tcatcacaac agttctgtac ctctccgatg cactccgtaa gaacttctta aatgaaaact
     3301 ttgattataa gatctgggat tcctactttt acctcgctgt catttttata aaccagttgt
     3361 gtctgcagct ggagatgttc acaccttcta aaaagaaaaa ggtgctagaa aagtatggtg
     3421 atatgcgcgt caccatgggt tgtgaaattt ttagcatgtg gcaaaaccta ggagaacaca
     3481 aacttcattt catccctgcc ctgattgggc cctttctgga agtaaccttg ataccccagc
     3541 cagatctccg gaatgtcatg attcctattt ttcacgatat gatggactgg gagcaaagaa
     3601 ggagtggcaa ctttaaacag gtggaggcca agctaattga caaattggac agcctgatgt
     3661 cggagggcaa aggtgatgaa acgtaccgtg agctcttcaa cagtataatt ccactatttg
     3721 gtccctaccc tagtctacta aagaaaattg agcgggaaac atggagggaa agtggcgttt
     3781 cattaattgc cactgtcact cggctgatgg agaggttgtt agactacagg gactgcatga
     3841 agataggaga ggtggatggc aagaagattg gctgcacagt tagccttttg aacttctata
     3901 agacggagct gaacaaggag gagatgtata tccgctacat ccacaaactc tacgatctgc
     3961 atctcaaggc gcagaacttc acagaggctg cctacactct cctgttgtat gacgagctgc
     4021 tggagtggtc tgatcggccc ctcagggagt tcctgaccta ccccatgcag accgaatggc
     4081 agcgcaagga gcacctgcac ctcaccatca tccagaactt cgaccgaggc aaatgttggg
     4141 agaatggcat tatcttgtgc cggaagattg cagagcaata tgagagttac tatgactaca
     4201 ggaacctgag caagatgagg atgatggaag cctccttgta tgacaaaatc atggaccagc
     4261 agcgcctgga acctgaattc ttcagagttg gattttatgg gaaaaagttt ccatttttct
     4321 taagaaataa ggagtttgta tgtcgagggc atgactatga aagactggag gccttccaac
     4381 agcgaatgct gaacgagttc ccccatgcca tcgccatgca gcatgccaac cagcccgacg
     4441 agaccatctt ccaggcagag gctcagtatt tacagatata tgctgtgact cccattccag
     4501 agagccagga ggtactgcag agagaggggg tcccagacaa catcaaaagc ttctataaag
     4561 tgaaccacat ttggaagttc cgctacgaca ggccattcca caaaggcgca aaagacaagg
     4621 agaacgaatt caagagtctc tgggtggaaa ggacatcgct gtacttggtc cagagcttac
     4681 ccggcatctc ccgctggttc gaagtggaaa agcgagaagt ggtagagatg agtcctctgg
     4741 aaaacgccat cgaagtgtta gaaaacaaga accagcagct gaagaccctg atcagccagt
     4801 gtcagacgag gcagatgcag aatatcaacc ccttgaccat gtgcctcaat ggagtcatag
     4861 atgctgcagt gaacggtggg gtctccaggt atcaagaggc attctttgtc aaagactata
     4921 ttttaagtca tcctgaagat ggggagaaga ttgcacggtt aagagaactg atgcttgagc
     4981 aggcacagat tctggaattt gggctggccg tgcacgagaa gtttgtacct caagatatga
     5041 gaccccttca caaaaaactg gtggaccagt tctttgtgat gaaatcgagc tttgggatac
     5101 aggagttccc tgcttgtatc caggccagcc ctgtccattt tcccaatgga agccctcgtg
     5161 tgtgtagaaa ctcagcccct gcttccatga gtccagatgg taccagggta atccctagac
     5221 gcagcccatt aagttaccca gctgtcaacc ggtattcctc gtcctcgctg tcctcacagg
     5281 cctctgctga agtaagcaat attacagggc aatcagaaag ctctgatgaa gtctttaaca
     5341 tgcagcccag tccgtctacc tcaagcctga gttccactca ctctgcttca cctaatgtga
     5401 ccagttctgc tccgtcgagt gccagagctt cgcctttgtt gtctgacaaa cacaaacatt
     5461 ccagagaaaa ctcttgcctg tccccaagag atagaccgtg cagtgccatt tacccaacac
     5521 ccgtggagcc ttctcagagg atgctgttta atcatattgg agatggggcc ttgcctcgaa
     5581 gtgaccccaa cctttctgca cctgagaaag ctgtgaatcc cacccctagc agctggagcc
     5641 tggacagtgg gaaagaagcc aagaacatgt cggacagtgg gaaacttatc tctccccctg
     5701 tccctccaag gcccacacag actgcttcgc cagcaagaca caccacatca gtgtccccct
     5761 cgcctgctgg acgttctcca ttgaagggct ccgtacagtc cttcacccca tctccagtgg
     5821 agtacaactc cccaggactg agttcaaatt ccccagtctt gtccggcagc tacagcagtg
     5881 ggatttcctc gcttagccgg tgtagcacgt cggaaacctc gggctttgaa aaccaagcca
     5941 atgaacagtc agtgcctgtg ccggtgccgg tgccggtgcc ggtgcccgtg cccagcttca
     6001 gcgggtcgga ggaacctgta cgcaaggaga gcaaaacccc acccccctac agtgtctacg
     6061 agcggactct gcggcgccct gtcccgctac ctcacagcct ctccatccct gtcacctctg
     6121 agccacctgc tctgcccccc aagcccttgg ctgcgcggtc cagccacctg gagaatggga
     6181 cccgtaggac tgagcctggc cctaggccca ggcccctgcc ccgtaaggtg tctcagctat
     6241 aagtcacttt tctatgtacc tgcgatgaat tctttgccgt ttacaagata agtctgatga
     6301 gaagacattt agtgtaggca ctttaaatct cttactcaga cctttcttta aatgaatgga
     6361 gttaaatttg cttattaata taatgttgca caatattaaa agttactgat ctaaaacgcc
     6421 agatgttaca tgaaatatgg ggctgagtct cattaaaacg tttctcattt gaaagtggta
     6481 aattgtgaaa aagactcctt ttgtaccttt ttatgttcac cttttttatg tagtttaatc
     6541 ttaaaaccaa tacgatattg tcaagcaata gaatgcgtga taatgttgta taccttttat
     6601 tctgaatact tgatactctg agaaagctga tcatgtctgg gcacatacta acacaacggc
     6661 catttcttga gacttcagga aagaaggtga agacctcagc tctccccttg agcagaatgt
     6721 tgagctccta tcttcagatt taaaggctaa agcaggctgg ttggttggag tagatactta
     6781 agggtttcaa ggattgggaa cggaagttgt tttgttcttt aaacaaaata cttctttgac
     6841 atctgacagc tgtctccatc cttaactctg ctttgtgaac ggttgctgaa tctttaagca
     6901 tcctgacacc atgctatcta ctgcattact tttcaaggtg caatttgctt tcggagttcc
     6961 aatcagctag attaagcaag agaccccagg agaagtgttt acttgaattt tgtgcttcct
     7021 tacttgataa cttcctacac aaaacgtgtc actgataaag agcaggtgtt caaggtttaa
     7081 ataggcacaa attactgtgt cccattaact aggattcggg aatcaataca ggacagtatt
     7141 aaatcaatag tgtgaaggaa gacaaaacct tagtgaaaat atattaacat gattgaatgg
     7201 tgaaaggact ttgaaaaggt gagggcatta actttgaatc ctgcataaaa taaagaattc
     7261 ttcaaactct cccttcttcc caggagagct gagtgtctct gctcgcttgt cctgtggtcc
     7321 tttttctggg gaagaggatt gtggaccatt ctagcatgga tacagcagca tagcattagg
     7381 tggaggtaga gtagacatga tggcacagtt gtaggagggt gaaaaagcac cttgtatgta
     7441 gtaatgtatt tttttaatct ttgtcttttc cttttactga ctgtttataa cactcaattg
     7501 acaatagata tgaactgtat tttaaaccat gctgttaaat attttccctc ttttgttggg
     7561 aagctcatct tagtttagtt gtgtttgttt ttgttgctag cttacctgga aggcagtgac
     7621 cactttttta tattctctta atgaaaccat tcagcaggta tatgctgttg aggctggtta
     7681 tagaggtttt ctataataaa tgttcaagta tttttgtaca taactggtta attttaataa
     7741 gagataccat tatgtgtaaa aaaaaaagta aaaagcaaac agttgtggat gcagtatgat
     7801 tgttataatt atgccaaata ctttatgtat ggaaaatatt tgtacatatg tgcttttaac
     7861 aataattctg ccatattgac tttacaattt tgaatgtcag aaaattaata tatgtaaaaa
     7921 tatttatgtt tagtgaaagt attcataatt gaggaaagga acctatgaat tttagctttg
     7981 tatcttgcag gttttgcagt tagaaatttc ttgaactagc gcttgcattt gataataaca
     8041 ctttgtgttt gtaatcacac cctaaaaaaa aa
//
