LOCUS       NM_021791               1481 bp    mRNA    linear   ROD 06-OCT-2024
DEFINITION  Mus musculus double C2, gamma (Doc2g), mRNA.
ACCESSION   NM_021791
VERSION     NM_021791.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1481)
  AUTHORS   Bourgeois-Jaarsma,Q., Miaja Hernandez,P. and Groffen,A.J.
  TITLE     Ca2+ sensor proteins in spontaneous release and synaptic
            plasticity: Limited contribution of Doc2c, rabphilin-3a and
            synaptotagmin 7 in hippocampal glutamatergic neurons
  JOURNAL   Mol Cell Neurosci 112, 103613 (2021)
   PUBMED   33753311
REFERENCE   2  (bases 1 to 1481)
  AUTHORS   Pang,Z.P., Bacaj,T., Yang,X., Zhou,P., Xu,W. and Sudhof,T.C.
  TITLE     Doc2 supports spontaneous synaptic transmission by a
            Ca(2+)-independent mechanism
  JOURNAL   Neuron 70 (2), 244-251 (2011)
   PUBMED   21521611
REFERENCE   3  (bases 1 to 1481)
  AUTHORS   Fukuda,M. and Mikoshiba,K.
  TITLE     Doc2gamma, a third isoform of double C2 protein, lacking
            calcium-dependent phospholipid binding activity
  JOURNAL   Biochem Biophys Res Commun 276 (2), 626-632 (2000)
   PUBMED   11027523
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC061104.1.
            
            On Apr 4, 2007 this sequence version replaced NM_021791.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC061104.1, AB046665.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1481              BC061104.1         1-1481
FEATURES             Location/Qualifiers
     source          1..1481
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="19"
                     /map="19 3.72 cM"
     gene            1..1481
                     /gene="Doc2g"
                     /gene_synonym="D830013O18Rik"
                     /note="double C2, gamma"
                     /db_xref="GeneID:60425"
                     /db_xref="MGI:MGI:1926250"
     exon            1..17
                     /gene="Doc2g"
                     /gene_synonym="D830013O18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            18..321
                     /gene="Doc2g"
                     /gene_synonym="D830013O18Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             78..1241
                     /gene="Doc2g"
                     /gene_synonym="D830013O18Rik"
                     /note="doc2-gamma"
                     /codon_start=1
                     /product="double C2-like domain-containing protein gamma"
                     /protein_id="NP_068563.2"
                     /db_xref="CCDS:CCDS29409.1"
                     /db_xref="GeneID:60425"
                     /db_xref="MGI:MGI:1926250"
                     /translation="MACAGPASGRQRVSMQEHMAIDVSPGPIRPIRLISNYFPHFYPF
                     LEPVLRAPDRQAMLAPAIPSAPQLQPNPEPEGDSDDSTALGTLEFTLLFDEDNSALHC
                     TAHRAKGLKPPAAGSVDTYVKANLLPGASKASQLRTRTVRGTREPVWEETLTYHGFTC
                     QDAGRKTLRLCVCEDSRLRRRRRGPPLGELRVPLRKLVPNRARSFDICLEKRKLTKRP
                     KSLDTARGMSLYEEEEMEAEVFGEERGRILLSLCYSSERGGLLVGVLRCVHLAPMDAN
                     GYSDPFVRLFLHPSSGKKSKYKTSVRRKTLNPEFNEEFFYAGHREELAQKALLVSVWD
                     YDLGTADDFIGGVQLSGRASGERLRHWRECLGHCDHRLELWHLLDSVPPQLGD"
     exon            322..401
                     /gene="Doc2g"
                     /gene_synonym="D830013O18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            402..473
                     /gene="Doc2g"
                     /gene_synonym="D830013O18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            474..583
                     /gene="Doc2g"
                     /gene_synonym="D830013O18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            584..719
                     /gene="Doc2g"
                     /gene_synonym="D830013O18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            720..773
                     /gene="Doc2g"
                     /gene_synonym="D830013O18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            774..931
                     /gene="Doc2g"
                     /gene_synonym="D830013O18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            932..1013
                     /gene="Doc2g"
                     /gene_synonym="D830013O18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1014..1110
                     /gene="Doc2g"
                     /gene_synonym="D830013O18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1111..1397
                     /gene="Doc2g"
                     /gene_synonym="D830013O18Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1377..1382
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Doc2g"
                     /gene_synonym="D830013O18Rik"
                     /note="hexamer: AATAAA"
     polyA_site      1397
                     /gene="Doc2g"
                     /gene_synonym="D830013O18Rik"
                     /note="major polyA site"
ORIGIN      
        1 gacacagctc tcaagaggtg tgtgctcggt gcccccagta ggtgggagct tctctgagtc
       61 cctatgtctg gaccaccatg gcatgtgcag ggccagccag tgggcgacag cgggtgagca
      121 tgcaggaaca catggccatc gatgtgagcc ctggccccat tcggcccatc cgcctcattt
      181 ccaactactt cccacatttc taccccttct tggagccggt gctgcgtgcc ccagatcggc
      241 aggcaatgct ggccccagcc atcccctctg caccccagct gcagcccaac cctgagcccg
      301 aaggagactc ggatgacagc actgccctag gcaccctaga attcacactt ctctttgatg
      361 aggacaacag cgccctgcac tgcacagccc atcgtgcaaa gggtctcaag ccaccagccg
      421 ccggctctgt ggacacctat gtcaaagcca acttactacc aggggccagc aaggccagcc
      481 agcttcggac acgcactgtt cgaggcacca gggaacctgt ctgggaggag actctcacct
      541 atcatggctt tacatgccag gatgctggac ggaagaccct gagactatgt gtgtgtgagg
      601 actcacggct gcggcgccgg cggcgaggac cccccctggg ggagctacga gtgcccctga
      661 ggaagctggt gccaaaccga gccaggagct ttgacatctg tctagagaag cggaagctga
      721 ccaagaggcc caagagcctg gacacagctc gtggcatgtc tctatatgag gaggaggaga
      781 tggaggcaga ggtgtttggg gaggagcgtg gccgcatcct actgtccctg tgctacagtt
      841 ccgagcgcgg tggcctgctg gtgggtgtgc tacgctgtgt tcaccttgct cccatggatg
      901 ccaatggcta ctcagacccc tttgtccgcc tgttcctgca tccaagttct gggaagaaat
      961 ccaaatataa gaccagtgtt cggaggaaga ccctgaaccc tgagttcaat gaggaattct
     1021 tttatgcagg tcatcgggag gagctagccc agaaggcact gctggtgtct gtgtgggact
     1081 atgacctggg cacagctgat gatttcattg gtggggtgca gctgagtggc agagccagtg
     1141 gggaacgcct gcgccactgg cgggagtgct taggccactg tgaccaccgg ctggaactgt
     1201 ggcacctgct ggacagcgtg cccccccaac ttggtgacta gtcagcacag cacagggccc
     1261 tgctgtgcaa ccagctcagg agccaagatg tctgctgcat ctggaaagag gtctgggcta
     1321 tcacatctgc tatgcattgt ctccttccag tcatgtaacc cccaaacaca aagcaaaata
     1381 aacacctgct tctgccaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
     1441 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa a
//
