LOCUS       NM_133763               1257 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus deoxynucleotidyltransferase, terminal, interacting
            protein 1 (Dnttip1), mRNA.
ACCESSION   NM_133763
VERSION     NM_133763.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1257)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1257)
  AUTHORS   Horisawa-Takada,Y., Kodera,C., Takemoto,K., Sakashita,A.,
            Horisawa,K., Maeda,R., Shimada,R., Usuki,S., Fujimura,S., Tani,N.,
            Matsuura,K., Akiyama,T., Suzuki,A., Niwa,H., Tachibana,M., Ohba,T.,
            Katabuchi,H., Namekawa,S.H., Araki,K. and Ishiguro,K.I.
  TITLE     Meiosis-specific ZFP541 repressor complex promotes developmental
            progression of meiotic prophase towards completion during mouse
            spermatogenesis
  JOURNAL   Nat Commun 12 (1), 3184 (2021)
   PUBMED   34075040
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1257)
  AUTHORS   Turnbull,R.E., Fairall,L., Saleh,A., Kelsall,E., Morris,K.L.,
            Ragan,T.J., Savva,C.G., Chandru,A., Millard,C.J., Makarova,O.V.,
            Smith,C.J., Roseman,A.M., Fry,A.M., Cowley,S.M. and Schwabe,J.W.R.
  TITLE     The MiDAC histone deacetylase complex is essential for embryonic
            development and has a unique multivalent structure
  JOURNAL   Nat Commun 11 (1), 3252 (2020)
   PUBMED   32591534
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1257)
  AUTHORS   Horiuchi,K., Perez-Cerezales,S., Papasaikas,P., Ramos-Ibeas,P.,
            Lopez-Cardona,A.P., Laguna-Barraza,R., Fonseca Balvis,N.,
            Pericuesta,E., Fernandez-Gonzalez,R., Planells,B., Viera,A.,
            Suja,J.A., Ross,P.J., Alen,F., Orio,L., Rodriguez de Fonseca,F.,
            Pintado,B., Valcarcel,J. and Gutierrez-Adan,A.
  TITLE     Impaired Spermatogenesis, Muscle, and Erythrocyte Function in U12
            Intron Splicing-Defective Zrsr1 Mutant Mice
  JOURNAL   Cell Rep 23 (1), 143-155 (2018)
   PUBMED   29617656
REFERENCE   5  (bases 1 to 1257)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   6  (bases 1 to 1257)
  AUTHORS   Yokoyama,S., Ito,Y., Ueno-Kudoh,H., Shimizu,H., Uchibe,K.,
            Albini,S., Mitsuoka,K., Miyaki,S., Kiso,M., Nagai,A., Hikata,T.,
            Osada,T., Fukuda,N., Yamashita,S., Harada,D., Mezzano,V., Kasai,M.,
            Puri,P.L., Hayashizaki,Y., Okado,H., Hashimoto,M. and Asahara,H.
  TITLE     A systems approach reveals that the myogenesis genome network is
            regulated by the transcriptional repressor RP58
  JOURNAL   Dev Cell 17 (6), 836-848 (2009)
   PUBMED   20059953
REFERENCE   7  (bases 1 to 1257)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   8  (bases 1 to 1257)
  AUTHORS   Yamashita,N., Shimazaki,N., Ibe,S., Kaneko,R., Tanabe,A.,
            Toyomoto,T., Fujita,K., Hasegawa,T., Toji,S., Tamai,K., Yamamoto,H.
            and Koiwai,O.
  TITLE     Terminal deoxynucleotidyltransferase directly interacts with a
            novel nuclear protein that is homologous to p65
  JOURNAL   Genes Cells 6 (7), 641-652 (2001)
   PUBMED   11473582
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC003486.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC003486.1, AK145239.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1257
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 85.27 cM"
     gene            1..1257
                     /gene="Dnttip1"
                     /gene_synonym="6430706C13Rik"
                     /note="deoxynucleotidyltransferase, terminal, interacting
                     protein 1"
                     /db_xref="GeneID:76233"
                     /db_xref="MGI:MGI:1923483"
     exon            1..144
                     /gene="Dnttip1"
                     /gene_synonym="6430706C13Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             40..1026
                     /gene="Dnttip1"
                     /gene_synonym="6430706C13Rik"
                     /note="tdIF1; tdT-interacting factor 1; terminal
                     deoxynucleotidyltransferase-interacting factor 1"
                     /codon_start=1
                     /product="deoxynucleotidyltransferase terminal-interacting
                     protein 1"
                     /protein_id="NP_598524.1"
                     /db_xref="CCDS:CCDS17054.1"
                     /db_xref="GeneID:76233"
                     /db_xref="MGI:MGI:1923483"
                     /translation="MGATGDTEQPRGPGGAERGGLELGDAGAAGQPVLTNPWNIMIKH
                     RQVQRRGRRSQMTTSFTDPAISMDLLRAVLQPSINEEIQGVFNKYMKFFQKAALNVRD
                     NVGEEVDAEQLIQEACRSCLEQAKLLFSDGEKVIPRLAHELPGIKRGRQAEEESHRGS
                     PIPKKRKGRPPGHVLSNDRAAAGMVWKQKSCEPIRREGPKWDPARLNESTTFVLGSRA
                     NKALGMGGTRGRIYIKHPHLFKYAADPQDKHWLAEQHHMRATGGKMAYLLIEEDIRDL
                     AASDDYRGCLDLKLEELKSFVLPSWMVEKMRKYMETLRTENEHRAAEAPPQT"
     exon            145..215
                     /gene="Dnttip1"
                     /gene_synonym="6430706C13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            216..312
                     /gene="Dnttip1"
                     /gene_synonym="6430706C13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            313..411
                     /gene="Dnttip1"
                     /gene_synonym="6430706C13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            412..480
                     /gene="Dnttip1"
                     /gene_synonym="6430706C13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            481..534
                     /gene="Dnttip1"
                     /gene_synonym="6430706C13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            535..593
                     /gene="Dnttip1"
                     /gene_synonym="6430706C13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            594..639
                     /gene="Dnttip1"
                     /gene_synonym="6430706C13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            640..698
                     /gene="Dnttip1"
                     /gene_synonym="6430706C13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            699..759
                     /gene="Dnttip1"
                     /gene_synonym="6430706C13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            760..831
                     /gene="Dnttip1"
                     /gene_synonym="6430706C13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            832..887
                     /gene="Dnttip1"
                     /gene_synonym="6430706C13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            888..1245
                     /gene="Dnttip1"
                     /gene_synonym="6430706C13Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1240..1245
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Dnttip1"
                     /gene_synonym="6430706C13Rik"
                     /note="hexamer: AATAAA"
     polyA_site      1245
                     /gene="Dnttip1"
                     /gene_synonym="6430706C13Rik"
                     /note="major polyA site"
ORIGIN      
        1 gctgagtcga gctgaggttg ttgtgggccg gggggcgcca tgggggcgac tggcgacacc
       61 gagcagccgc ggggccccgg cggggcggag cgaggtggcc tggagctggg cgacgcgggc
      121 gcggcgggcc agccggttct cacgaaccct tggaacataa tgataaaaca tcggcaggtg
      181 cagcgaaggg gccgccgatc tcagatgacc acaagtttca cagacccagc catctctatg
      241 gatctcctcc gtgctgtcct gcagcctagc atcaatgagg agatccaggg tgtcttcaac
      301 aagtacatga agttcttcca gaaggcagcg ctgaatgtgc gagacaatgt tggggaagaa
      361 gtggacgcag agcagttgat tcaggaggcc tgccgcagct gcctggagca ggcaaagctg
      421 ctcttttctg atggagagaa agtgataccc agattggccc atgagcttcc agggatcaag
      481 cggggccggc aagcagaaga ggagtcccac cgaggaagcc ccattcccaa aaagaggaaa
      541 ggtcggcctc ctggacacgt cctgtcaaat gaccgcgcag ctgctggcat ggtatggaaa
      601 caaaaatcct gtgaaccaat tcgccgagaa ggccccaagt gggacccagc tcggctgaat
      661 gaatctacca cctttgtttt ggggtctcga gccaacaagg ccttggggat gggaggcacc
      721 agagggagaa tctacatcaa gcacccacac ctctttaagt atgcagcaga tcctcaggac
      781 aagcactggc tggctgagca gcatcacatg cgggcaacag gcggaaagat ggcgtacctt
      841 ctcattgaag aagacatccg ggacttggct gccagcgatg actacagagg atgcttggac
      901 ctgaagttgg aggagctgaa atcctttgtt ctgccatcct ggatggttga gaagatgcgg
      961 aaatacatgg agacactgcg gacagaaaat gagcaccgcg ctgcggaagc gcctccccag
     1021 acctgagccg ggtgtcctgg ctactacact tggcggcctg cctccaagac cctctttccc
     1081 cacccggctg aggccatcat ggggatttgg tctagttgac tcttaacagc attaagctgt
     1141 acatgagcta gtttgtagtg actcactgca gagcacccca gactggcatg tggttctgtt
     1201 tctaaagtta ttggaataag aagcaattaa acagtttgta ataaaaaaaa aaaaaaa
//
