LOCUS       NM_001043228            2073 bp    mRNA    linear   ROD 07-JAN-2025
DEFINITION  Mus musculus deoxynucleotidyltransferase, terminal (Dntt),
            transcript variant 2, mRNA.
ACCESSION   NM_001043228
VERSION     NM_001043228.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2073)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2073)
  AUTHORS   Textor,J., Buytenhuijs,F., Rogers,D., Gauthier,E.M., Sultan,S.,
            Wortel,I.M.N., Kalies,K., Fahnrich,A., Pagel,R., Melichar,H.J.,
            Westermann,J. and Mandl,J.N.
  TITLE     Machine learning analysis of the T cell receptor repertoire
            identifies sequence features of self-reactivity
  JOURNAL   Cell Syst 14 (12), 1059-1073 (2023)
   PUBMED   38061355
REFERENCE   3  (bases 1 to 2073)
  AUTHORS   Klein,F., Roux,J., Cvijetic,G., Rodrigues,P.F., von Muenchow,L.,
            Lubin,R., Pelczar,P., Yona,S., Tsapogas,P. and Tussiwand,R.
  TITLE     Dntt expression reveals developmental hierarchy and lineage
            specification of hematopoietic progenitors
  JOURNAL   Nat Immunol 23 (4), 505-517 (2022)
   PUBMED   35354960
  REMARK    GeneRIF: Dntt expression reveals developmental hierarchy and
            lineage specification of hematopoietic progenitors.
REFERENCE   4  (bases 1 to 2073)
  AUTHORS   Oliver,B.L., Young,C.A. and Munnamalai,V.
  TITLE     Spatial and temporal expression of PORCN is highly dynamic in the
            developing mouse cochlea
  JOURNAL   Gene Expr Patterns 42, 119214 (2021)
   PUBMED   34547456
REFERENCE   5  (bases 1 to 2073)
  AUTHORS   Stutz,R., Meyer,C., Kaiser,E., Goedicke-Fritz,S., Schroeder,H.W.
            Jr., Bals,R., Haertel,C., Rogosch,T., Kerzel,S. and Zemlin,M.
  TITLE     Attenuated asthma phenotype in mice with a fetal-like antigen
            receptor repertoire
  JOURNAL   Sci Rep 11 (1), 14199 (2021)
   PUBMED   34244568
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 2073)
  AUTHORS   Disteche,C.M., Brannan,C.I., Larsen,A., Adler,D.A.,
            Schorderet,D.F., Gearing,D., Copeland,N.G., Jenkins,N.A. and
            Park,L.S.
  TITLE     The human pseudoautosomal GM-CSF receptor alpha subunit gene is
            autosomal in mouse
  JOURNAL   Nat Genet 1 (5), 333-336 (1992)
   PUBMED   1363815
REFERENCE   7  (bases 1 to 2073)
  AUTHORS   Watanabe-Fukunaga,R., Brannan,C.I., Itoh,N., Yonehara,S.,
            Copeland,N.G., Jenkins,N.A. and Nagata,S.
  TITLE     The cDNA structure, expression, and chromosomal assignment of the
            mouse Fas antigen
  JOURNAL   J Immunol 148 (4), 1274-1279 (1992)
   PUBMED   1371136
REFERENCE   8  (bases 1 to 2073)
  AUTHORS   Benovic,J.L., Onorato,J.J., Arriza,J.L., Stone,W.C., Lohse,M.,
            Jenkins,N.A., Gilbert,D.J., Copeland,N.G., Caron,M.G. and
            Lefkowitz,R.J.
  TITLE     Cloning, expression, and chromosomal localization of
            beta-adrenergic receptor kinase 2. A new member of the receptor
            kinase family
  JOURNAL   J Biol Chem 266 (23), 14939-14946 (1991)
   PUBMED   1869533
REFERENCE   9  (bases 1 to 2073)
  AUTHORS   Watanabe,T., Sakai,Y., Miyawaki,S., Shimizu,A., Koiwai,O. and
            Ohno,K.
  TITLE     A molecular genetic linkage map of mouse chromosome 19, including
            the lpr, Ly-44, and Tdt genes
  JOURNAL   Biochem Genet 29 (7-8), 325-335 (1991)
   PUBMED   1684099
REFERENCE   10 (bases 1 to 2073)
  AUTHORS   Glaser,T., Matthews,K.E., Hudson,J.W., Seth,P., Housman,D.E. and
            Crerar,M.M.
  TITLE     Localization of the muscle, liver, and brain glycogen phosphorylase
            genes on linkage maps of mouse chromosomes 19, 12, and 2,
            respectively
  JOURNAL   Genomics 5 (3), 510-521 (1989)
   PUBMED   2575583
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC126608.20, AF316015.1 and BX639078.1.
            
            Transcript Variant: This variant (2) lacks an in-frame exon in the
            3' coding region, compared to variant 1. The encoded isoform (2) is
            shorter, compared to isoform 1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK134009.1, X68670.2 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849383, SAMN04095719
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-147               AC126608.20        120625-120771
            148-1801            AF316015.1         1-1654
            1802-2073           BX639078.1         1-272               c
FEATURES             Location/Qualifiers
     source          1..2073
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="19"
                     /map="19 34.32 cM"
     gene            1..2073
                     /gene="Dntt"
                     /gene_synonym="Tdt"
                     /note="deoxynucleotidyltransferase, terminal"
                     /db_xref="GeneID:21673"
                     /db_xref="MGI:MGI:98659"
     exon            1..367
                     /gene="Dntt"
                     /gene_synonym="Tdt"
                     /inference="alignment:Splign:2.1.0"
     exon            368..542
                     /gene="Dntt"
                     /gene_synonym="Tdt"
                     /inference="alignment:Splign:2.1.0"
     exon            543..671
                     /gene="Dntt"
                     /gene_synonym="Tdt"
                     /inference="alignment:Splign:2.1.0"
     exon            672..842
                     /gene="Dntt"
                     /gene_synonym="Tdt"
                     /inference="alignment:Splign:2.1.0"
     exon            843..914
                     /gene="Dntt"
                     /gene_synonym="Tdt"
                     /inference="alignment:Splign:2.1.0"
     exon            915..1038
                     /gene="Dntt"
                     /gene_synonym="Tdt"
                     /inference="alignment:Splign:2.1.0"
     exon            1039..1171
                     /gene="Dntt"
                     /gene_synonym="Tdt"
                     /inference="alignment:Splign:2.1.0"
     exon            1172..1280
                     /gene="Dntt"
                     /gene_synonym="Tdt"
                     /inference="alignment:Splign:2.1.0"
     exon            1281..1526
                     /gene="Dntt"
                     /gene_synonym="Tdt"
                     /inference="alignment:Splign:2.1.0"
     exon            1527..1610
                     /gene="Dntt"
                     /gene_synonym="Tdt"
                     /inference="alignment:Splign:2.1.0"
     exon            1611..2070
                     /gene="Dntt"
                     /gene_synonym="Tdt"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1954..1959
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Dntt"
                     /gene_synonym="Tdt"
                     /note="hexamer: AATAAA"
     polyA_site      1975
                     /gene="Dntt"
                     /gene_synonym="Tdt"
                     /note="major polyA site"
     regulatory      2044..2049
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Dntt"
                     /gene_synonym="Tdt"
                     /note="hexamer: AATAAA"
     polyA_site      2067
                     /gene="Dntt"
                     /gene_synonym="Tdt"
                     /note="major polyA site"
ORIGIN      
        1 aagagctcca ttttgggaga aaggacctga tcagagtgag acattccttc agcaggaagt
       61 tgtcaccagg gtggtaccta tgggtttgct ggtgagagga catcagagcc ctcattctgg
      121 agacaccacc tgatggtaca gacagagcta gactgtctgc ttccatggat ccactgcaag
      181 cagtccacct gggtcctcgg aagaaaagac ccaggcagct gggcacccca gtggcttcca
      241 cgccttatga catccgattt cgagacttgg tcctcttcat tttggaaaag aagatgggaa
      301 caactcgaag agccttcctc atggagctgg cccgaaggaa agggttcagg gtggaaaatg
      361 agctcagtga ttcggtcacc cacattgtgg cagagaacaa ctcagggtca gacgtcctgg
      421 agtggctcca gctgcagaac atcaaagcca gctccgagct cgaactcttg gacatctcct
      481 ggctcatcga atgcatggga gctgggaagc cagtggagat gatggggaga catcagcttg
      541 ttgtgaatag aaactcctcc ccgagtcctg tcccaggctc ccagaatgtt ccagcacctg
      601 ctgtgaagaa gatctcccaa tatgcttgcc agcgaagaac cacattaaac aattacaacc
      661 aactattcac ggatgccctt gatatcctgg ctgaaaatga tgagcttaga gagaatgaag
      721 gttcttgcct ggcattcatg cgagcgtcct ctgtactgaa atctctgcca ttccccatca
      781 ccagcatgaa agacacagag gggattcctt gcctagggga caaggtgaag agtatcatag
      841 agggaattat tgaagatgga gaaagttctg aagctaaagc tgtgttaaat gatgagcgat
      901 ataaatcctt caaactcttt acctctgtgt ttggtgtggg actgaagaca gctgagaaat
      961 ggttcaggat gggtttcaga actctcagca aaatacaatc agacaaaagc ctgaggttta
     1021 cacaaatgca gaaagcagga ttcctctact acgaagacct cgttagctgt gtgaacaggc
     1081 cagaagccga ggctgtcagc atgctagtta aggaggcggt tgtgacattt cttccagatg
     1141 ccttggtcac catgactggg gggttccgca ggggtaagat gactggacat gatgtagact
     1201 ttctaattac cagcccagaa gccacagagg atgaagagca gcagctcttg cataaagtga
     1261 cagacttttg gaagcagcag gggttgcttt tgtactgcga catcttagag tcaacctttg
     1321 aaaagttcaa gcagcccagc aggaaggtgg atgctctcga ccatttccag aaatgcttcc
     1381 tgattctgaa gctggaccac gggagagtgc acagcgagaa gagcggccag caggaaggaa
     1441 agggctggaa ggccatccgt gtagatctgg tcatgtgccc ctatgatcgc cgggccttcg
     1501 ccctgcttgg atggaccggc tccagacagt ttgagagaga cttgcggcgc tatgccacac
     1561 acgagaggaa gatgatgctg gacaaccacg ccctgtatga caggactaag agggtgtttc
     1621 ttgaagcaga aagtgaagaa gagatctttg cccatctggg actggactac attgaaccat
     1681 gggaaagaaa tgcctaagac ggagttgttg acatttttct tttcggttta gacaagctgt
     1741 gctctgtgtt agtaaaagat ggcttgggaa agtctgggat tctttgacct cagaggatgc
     1801 tggcagcaag tggatcataa gtatactatg cagagagaat attctaaggc aactttgaag
     1861 tcttgataaa ccaggatgca gccatggttc acattcttgg gccatctgtc ctactgttgc
     1921 atagaattca tagtcttttg tctgctttgt ttgaataaaa atggtcttgt cattgcagca
     1981 tcatctagag aagcgcatca atgcccacct gactcctgtg tgtctgaatc tctgtgtatt
     2041 gccaataaaa ataggaaaca gaagcatgaa aaa
//
