LOCUS       NM_028029               6103 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus dynamin binding protein (Dnmbp), transcript variant 1,
            mRNA.
ACCESSION   NM_028029
VERSION     NM_028029.5
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6103)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 6103)
  AUTHORS   Yoo,D., Park,J., Lee,C., Song,I., Lee,Y.H., Yun,T., Lee,H.,
            Heguy,A., Han,J.Y., Dasen,J.S., Kim,H. and Baek,M.
  TITLE     Little skate genome provides insights into genetic programs
            essential for limb-based locomotion
  JOURNAL   Elife 11, e78345 (2022)
   PUBMED   36288084
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 6103)
  AUTHORS   Choquet,H., Melles,R.B., Anand,D., Yin,J., Cuellar-Partida,G.,
            Wang,W., Hoffmann,T.J., Nair,K.S., Hysi,P.G., Lachke,S.A. and
            Jorgenson,E.
  CONSRTM   23andMe Research Team
  TITLE     A large multiethnic GWAS meta-analysis of cataract identifies new
            risk loci and sex-specific effects
  JOURNAL   Nat Commun 12 (1), 3595 (2021)
   PUBMED   34127677
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 6103)
  AUTHORS   Sheehan,C.J., McMahon,J.J., Serdar,L.D. and Silver,D.L.
  TITLE     Dosage-dependent requirements of Magoh for cortical interneuron
            generation and survival
  JOURNAL   Development 147 (1) (2020)
   PUBMED   31857347
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 6103)
  AUTHORS   Oda,Y., Otani,T., Ikenouchi,J. and Furuse,M.
  TITLE     Tricellulin regulates junctional tension of epithelial cells at
            tricellular contacts through Cdc42
  JOURNAL   J Cell Sci 127 (Pt 19), 4201-4212 (2014)
   PUBMED   25097232
REFERENCE   6  (bases 1 to 6103)
  AUTHORS   Rajabian,T., Gavicherla,B., Heisig,M., Muller-Altrock,S.,
            Goebel,W., Gray-Owen,S.D. and Ireton,K.
  TITLE     The bacterial virulence factor InlC perturbs apical cell junctions
            and promotes cell-to-cell spread of Listeria
  JOURNAL   Nat Cell Biol 11 (10), 1212-1218 (2009)
   PUBMED   19767742
REFERENCE   7  (bases 1 to 6103)
  AUTHORS   Kovacs,E.M., Makar,R.S. and Gertler,F.B.
  TITLE     Tuba stimulates intracellular N-WASP-dependent actin assembly
  JOURNAL   J Cell Sci 119 (Pt 13), 2715-2726 (2006)
   PUBMED   16757518
  REMARK    GeneRIF: Tuba-stimulated dorsal ruffling might represent a novel
            mechanism for the coordination of N-WASP-dependent cytoskeletal
            rearrangements, and Tuba function is implicated in motility
            processes.
REFERENCE   8  (bases 1 to 6103)
  AUTHORS   Dike,S., Balija,V.S., Nascimento,L.U., Xuan,Z., Ou,J., Zutavern,T.,
            Palmer,L.E., Hannon,G., Zhang,M.Q. and McCombie,W.R.
  TITLE     The mouse genome: experimental examination of gene predictions and
            transcriptional start sites
  JOURNAL   Genome Res 14 (12), 2424-2429 (2004)
   PUBMED   15574821
REFERENCE   9  (bases 1 to 6103)
  AUTHORS   Salazar,M.A., Kwiatkowski,A.V., Pellegrini,L., Cestra,G.,
            Butler,M.H., Rossman,K.L., Serna,D.M., Sondek,J., Gertler,F.B. and
            De Camilli,P.
  TITLE     Tuba, a novel protein containing bin/amphiphysin/Rvs and Dbl
            homology domains, links dynamin to regulation of the actin
            cytoskeleton
  JOURNAL   J Biol Chem 278 (49), 49031-49043 (2003)
   PUBMED   14506234
REFERENCE   10 (bases 1 to 6103)
  AUTHORS   Yoshizawa,M., Sone,M., Matsuo,N., Nagase,T., Ohara,O., Nabeshima,Y.
            and Hoshino,M.
  TITLE     Dynamic and coordinated expression profile of dbl-family guanine
            nucleotide exchange factors in the developing mouse brain
  JOURNAL   Gene Expr Patterns 3 (3), 375-381 (2003)
   PUBMED   12799088
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC132251.3.
            
            On Mar 29, 2022 this sequence version replaced NM_028029.4.
            
            Summary: This gene encodes a member of the DBL family of guanine
            nucleotide exchange factors. The encoded protein has been proposed
            to regulate the actin cytoskeleton by specifically activating the
            Rho-family GTPase Cdc42. An interaction between the encoded protein
            and a Listeria protein has been shown to mediate Listeria
            infection. Alternative splicing results in multiple transcript
            variants. [provided by RefSeq, Apr 2015].
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: partial sample support SAMN00849374, SAMN00849375
                              [ECO:0000350]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-77                AC132251.3         20531-20607
            78-232              AC132251.3         48335-48489
            233-355             AC132251.3         49877-49999
            356-2344            AC132251.3         57666-59654
            2345-2538           AC132251.3         85704-85897
            2539-2668           AC132251.3         86467-86596
            2669-2816           AC132251.3         90415-90562
            2817-3016           AC132251.3         91720-91919
            3017-3147           AC132251.3         93067-93197
            3148-3252           AC132251.3         94031-94135
            3253-3381           AC132251.3         104094-104222
            3382-3714           AC132251.3         105595-105927
            3715-3894           AC132251.3         106412-106591
            3895-4093           AC132251.3         108302-108500
            4094-4644           AC132251.3         110398-110948
            4645-6103           AC132251.3         112446-113904
FEATURES             Location/Qualifiers
     source          1..6103
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="19"
                     /map="19 36.67 cM"
     gene            1..6103
                     /gene="Dnmbp"
                     /gene_synonym="2410003L07Rik; 2410003M15Rik; TUBA"
                     /note="dynamin binding protein"
                     /db_xref="GeneID:71972"
                     /db_xref="MGI:MGI:1917352"
     exon            1..77
                     /gene="Dnmbp"
                     /gene_synonym="2410003L07Rik; 2410003M15Rik; TUBA"
                     /inference="alignment:Splign:2.1.0"
     exon            78..232
                     /gene="Dnmbp"
                     /gene_synonym="2410003L07Rik; 2410003M15Rik; TUBA"
                     /inference="alignment:Splign:2.1.0"
     exon            233..355
                     /gene="Dnmbp"
                     /gene_synonym="2410003L07Rik; 2410003M15Rik; TUBA"
                     /inference="alignment:Splign:2.1.0"
     exon            356..2344
                     /gene="Dnmbp"
                     /gene_synonym="2410003L07Rik; 2410003M15Rik; TUBA"
                     /inference="alignment:Splign:2.1.0"
     exon            2345..2538
                     /gene="Dnmbp"
                     /gene_synonym="2410003L07Rik; 2410003M15Rik; TUBA"
                     /inference="alignment:Splign:2.1.0"
     exon            2539..2668
                     /gene="Dnmbp"
                     /gene_synonym="2410003L07Rik; 2410003M15Rik; TUBA"
                     /inference="alignment:Splign:2.1.0"
     exon            2669..2816
                     /gene="Dnmbp"
                     /gene_synonym="2410003L07Rik; 2410003M15Rik; TUBA"
                     /inference="alignment:Splign:2.1.0"
     exon            2817..3016
                     /gene="Dnmbp"
                     /gene_synonym="2410003L07Rik; 2410003M15Rik; TUBA"
                     /inference="alignment:Splign:2.1.0"
     exon            3017..3147
                     /gene="Dnmbp"
                     /gene_synonym="2410003L07Rik; 2410003M15Rik; TUBA"
                     /inference="alignment:Splign:2.1.0"
     exon            3148..3252
                     /gene="Dnmbp"
                     /gene_synonym="2410003L07Rik; 2410003M15Rik; TUBA"
                     /inference="alignment:Splign:2.1.0"
     exon            3253..3381
                     /gene="Dnmbp"
                     /gene_synonym="2410003L07Rik; 2410003M15Rik; TUBA"
                     /inference="alignment:Splign:2.1.0"
     exon            3382..3714
                     /gene="Dnmbp"
                     /gene_synonym="2410003L07Rik; 2410003M15Rik; TUBA"
                     /inference="alignment:Splign:2.1.0"
     exon            3715..3894
                     /gene="Dnmbp"
                     /gene_synonym="2410003L07Rik; 2410003M15Rik; TUBA"
                     /inference="alignment:Splign:2.1.0"
     exon            3895..4093
                     /gene="Dnmbp"
                     /gene_synonym="2410003L07Rik; 2410003M15Rik; TUBA"
                     /inference="alignment:Splign:2.1.0"
     exon            4094..4644
                     /gene="Dnmbp"
                     /gene_synonym="2410003L07Rik; 2410003M15Rik; TUBA"
                     /inference="alignment:Splign:2.1.0"
     exon            4645..6103
                     /gene="Dnmbp"
                     /gene_synonym="2410003L07Rik; 2410003M15Rik; TUBA"
                     /inference="alignment:Splign:2.1.0"
     regulatory      6083..6088
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Dnmbp"
                     /gene_synonym="2410003L07Rik; 2410003M15Rik; TUBA"
                     /note="hexamer: AATAAA"
     polyA_site      6103
                     /gene="Dnmbp"
                     /gene_synonym="2410003L07Rik; 2410003M15Rik; TUBA"
                     /note="major polyA site"
ORIGIN      
        1 gctgagggga ggtgaccgcg gcccggccgg gccaccagtg gctgtgcgcg gagggaacgc
       61 cgagcggcag agagcagttt gggaagcatg gagcctggat ccatggtccg agccatcttt
      121 gacttctgcc ctagcgtctc agaggaactg ccactcttcg tgggggacgt tattgaggtg
      181 ctggccgtgg tggatgaatt ttggctccta gggaagaagg aagatgttac aggacagttc
      241 cccagcagtt ttgtggagat cgtgacaatt cccagtctga aagagggcga gaggctgttt
      301 gtctgcatct gcgaattcgt atctcgagag ctgaacagtc tttccctcca tcggggagac
      361 ctggtgattc tcgacgacag cgctcccact gcaggatggc tgcagggccg aagctgctgg
      421 ggcgcttggg gcttcttccc atcctcctgt gtccaggagc tctgcctctc ctctcggagc
      481 cgacgctggc acgcacagag tgcgttgctt caggccccag agtactccct gggacaagca
      541 cgggccctca tgggcctttc tgcccagttg gacgaggagt tggatttcag ggaaggagac
      601 ctgatcacca ttatcggggt tcctgagccg ggctggtttg agggagagtt agagggtcgg
      661 aggggcattt tcccagaagg ttttgtagag ctgctggggc ccctaaggac tgtggatgag
      721 tccgtaaact ccagaagtgg agatgactcc gctgtcaacg gtgaggtgga tgtccctcca
      781 gaagaagcag agagtggagg cgacgaggac gaccagcagt cggggaccta tggaatcgcc
      841 ctctacagat tccaagccct ggagacgaat gagttggact ttgaggtagg ggacagaatt
      901 caaatactgg ggaccttgga ggatggctgg ctggaaggat gtctgaaggg caagacaggg
      961 gtctttcccc atcgctttgt gaagttatgt cctagcaaca ggacagagga aaccacggct
     1021 cagccccagg aaagcagttt ccccaaggac tctgaaagct ctgtgggcaa gtcaggggac
     1081 tccgtggtgg aggaagcaag acaggaacca tgggagtgtg aagaagaaag acctgactat
     1141 gatctcccag gacaagcctc cgtgccccaa gatcacgtag cacccgagtg gactggagat
     1201 acgatctcag gtcaggataa agatgcttca gggagctctc ctgatgtgga tcttgaaagg
     1261 cctcttgcta aagacctttc cacacctgac ccctcagagg aagtcaacgg tgtttcttcc
     1321 cagcctcagg tacctattca tcccaaagtg cagaagagcc aacactatct aacagcagga
     1381 gggagccacc aaacctctga cccattctct gagcttgtcc cactagaagc caggaccaga
     1441 gactactcca gcctgcctcc tagaagaaca tacgcccaag gttggtcatt ccagaagcca
     1501 gcgtcccacc tccagagggc ctcttccctt acagcctcaa ggctagacag acccagccac
     1561 ttttgccatc cagccatggc cagctatgct cagaagcacc aaacatctac agaaaatact
     1621 gccagcctcc acgatccacc agagagacca gagagaaggc ctggcttaca agacaggggg
     1681 cctgccacag atataaccac agcgtcacag ggggacagcc tggacctaga ttccaagttg
     1741 acccaacagc tgatagagtt tgagaagagt ctgtcagggc ccagcacaga gccagagacg
     1801 attgtacgcc gcttttcaat catggacttt tactctgaga aggatatcgt gagaggctcc
     1861 tcaaattcac taccctcaca ggctttcccc gagaggagaa agaccctgag gccaccacct
     1921 cctagacccc gtaccccaac acccatttcc tcccacttgc tagttgacca gagcccgaaa
     1981 cctgtaccca ccttggttgt gcggccctcc cgaccagctc ctctgcctcc tcctgcccag
     2041 cagaggatga atacggcctc ccccaagccc acctcctgtg cccatcctgg ctgggaggcc
     2101 ccagagaagg aggactctga gcacatggag aagagcccag cccagacttt tccgtgcccc
     2161 tccatgctgg caaggatccg ggacgtggaa caggacctgg acacgtgtac cagggctcag
     2221 gaagagctga acttgctgtt ggaggaaaag caagatgacc cgtcgagggc agagactctt
     2281 gagactctca gatcctacga gagcaccatt cagagcctga ccctggagct tcagcagctg
     2341 agagacatga cgctcctctc ttcccagtct tcatccctgg cggccccctt tgggtctgtg
     2401 tccactgaaa acccagagca gaggatgctg gagaagagag ccaaggtggt ggcggagctt
     2461 ttgcagacgg agagagacta catccgggat ctggagatgt gcattgagag ggtcatggtg
     2521 cccctgcagc aggcacaggt accaaacgtt gattttgaag gactttttgg aaatatgcaa
     2581 acagtgatta aagtctcaaa gcaattgttg gcggccttgg aaatcagcga tgctgtaggt
     2641 atgagctcat gcgattgttt ggtcccagga cccgtgtttc ttgaccaccg agacgagctt
     2701 gagggaacgt acagggttta ctgccagaac cacgatgaag ccatctccct gctggaaatg
     2761 tatgagaagg acgagaagac ccagaagcac cttcaggact acctggcaga tctcaaggga
     2821 tgcaccaatt acatcaacct gggctccttc ctcatcaagc ccgtacagag aataatgcgt
     2881 tacccgctgc tgctgatgga gttgctgaat tccaccccag aatcccaccc ggataaagtg
     2941 cctttaacca acgcggtcct cgccgtcaag gagatcaatg ttaacattaa tgagtacaag
     3001 cgtcggaagg atctggtgct taagtaccgc aaaggggatg aagatagcct gatggaaaag
     3061 atctccaagc tgaacataca ctccatcatc aagaagtcca gccgcgttag cagccacctc
     3121 aaacacctca ctggcttcgc tccgcagcta aaagatgaag tatttgaaga gacagaaaag
     3181 aacttccgga tgcaggagag attgattaaa tcttttatcc gagacctgtc cctctacctc
     3241 cagcatatac gggaatctgc atgtgtgaag gtggtggcag ccatgagcat atgggatctg
     3301 tgcatggaga ggggacatca tgacctggag cagttcgaga aggtgcatcg ctacatcagt
     3361 gaccagctct tcacacggtt taaagagagg accgagcggc tcgtcatcaa tcccttaaac
     3421 cagttgttga acatgttcac ggggccctac aagctggtgc agaagcggtt cgacaagctc
     3481 ctggacttct acaactgcac tgagcgagcg gagaagctga aggacaagaa gactctggag
     3541 gagctgcagt cagcccgaaa caactacgag gccctgaact cgcagctgct ggacgagctg
     3601 cccaagttcc agcagtacgc ccagagcctc ttcaccaact gcatccacgg ctatgccgaa
     3661 gcccactgtg acttcgtgca gcaagccctg gagcagctgc agccgctgct gtcgttactg
     3721 aaagccaccg accgagaagg caacttgatc gccatcttcc ttgaggagca cagccgggtg
     3781 ctacagcagc tccaggtctt cacattcttc cccgagtccc tcccagcgcc caggaagccc
     3841 tttgagagga aaaccacaga ccgccagtca tcccggaaga cccttctggg catgccaagc
     3901 tacatgctgc agtcggaaga gctgcggagc tccctgctgg cgaggtaccc gccggaaaag
     3961 ctcttccacg tccagcggaa cttcaacgct gcgcaggact tggatgtctc ccttttggaa
     4021 ggcgacctgg tgggcgtgat caaaaagaaa gaccccatgg gcagccagaa ccgctggctc
     4081 gtggacaacg gagtcaccaa aggctttgtc tacagctcct tcctgaagcc ttacaatcct
     4141 cgctgcagcc attcggatgc ctccgtggcc agccactcct ccacggagtc agagcacagt
     4201 ggctcctccc ccgggtgcca tcgacagaac agccacagtg ccttgacctt caactccaac
     4261 aacatgactg tgtccttcac ctcaggactt gccctaacgc agcctcagga tgcatctcca
     4321 ctgaaggact gtgcccacga aactctcgct gtgtcctgga acacagggca tccagagact
     4381 ggaccttcca cgtgctcttc cgacccaggc ttttcctgcc agcgcaggct ggggaaccct
     4441 gcagatggtg ccagagacat cagccaacct gcttcaacct tgaggggctg ccagcgaggc
     4501 tccccgcatt cagaagtggt cggttactct gtgccagggc aaaatgacca aggcagtgac
     4561 tctataaaag gctctgcaag agtctgtcag gctccagaag acagagacag aggggtcggg
     4621 agcagcgaga cagagggcaa ccaggtctat tttgccattt atactttcaa ggcacgaaac
     4681 ccaaatgaac tgagtgtgtt agccaatcag agactcagga tccatgagtt taaagacgtc
     4741 acaggcaata cagagtggtg gttggctgaa gttaacggaa ggaagggcta cgtcccatcc
     4801 aactatatcc ggaaaaccga gtacacctga gccaagttgc ctcccgccct gccttgctgc
     4861 cgctttcagt ccgacggaag gtcctggagg gcttcgggct cctgctcccg agcagggacc
     4921 caccacactg cctatccata actcggagcg caagataagc tttgttctga ttgggttgta
     4981 cactttgatg ctcgctagaa tttgaagtgg gtggacccca aatgtttgcc agtgattccg
     5041 tgtccacaag aagcaggcca agtgccggtg tcagctttgg gaaatgagac gttcccaatc
     5101 agagaagcag tattgtacgc gggaagctgt gccagcatca gcggatgctg gcattggttg
     5161 ccgcactcca tggtcgactg agcagtcacg gggtgaggag gagtgggctc cgagagctcc
     5221 tcctttatgc ccccatccac ggtcttgtca caatcacacc aaacctggtg tgtcagagtg
     5281 ttcgagacac cccggtgccc ggcagccttc tctctgacac ttgcccctcc tagttcttaa
     5341 catgctaacc tttcactgct tccccgttga atgtttacag tctaactttt attctgaccg
     5401 tgtgtctgaa aggttccctt accttgtcga acacggtcag ctgcctcttc cctgacactc
     5461 atttcaactt tatttgatct ctatgatgtc tcctaacctt tctcccagta cgcgataact
     5521 aacggacttc cctagactag gggggctcgg ggctcggcac tccgcccagc cactgaacgt
     5581 agtcattcat tctgccggtg gaaacgggac gcctgcccct cccctttcca cccttgcact
     5641 tggctgcctc tagtcacctc cacgcgtgct caagacaacc acgtggctta ttcaaagtag
     5701 gtaggatcag tggccccaga agcttgtctt agagtcggag ataagtattt tccttctcac
     5761 cacctactgc catacttcag agacaatatt caaagtcaga cagatgctaa agtgcctaat
     5821 gagacctcaa acccaaggct ggaaggtggc cgctaaaccc tcatgtgagg aaatggcccg
     5881 agagacttgt ctcagcgtgg gtcttagact ccaggtcttc cccatccttc cagccgctgc
     5941 tcttctagct gcacatttgg ccttaaagtc ctgatgagtc aggacttgcc tgtggacacc
     6001 catccacggc tgcaccactg gtcagagcct cgtatgaagt gtttatattt agaaatgttt
     6061 atatttaagt agctatttta taaataaaag catttctatt gac
//
