LOCUS       NM_173383               1490 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus DND microRNA-mediated repression inhibitor 1 (Dnd1),
            mRNA.
ACCESSION   NM_173383
VERSION     NM_173383.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1490)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1490)
  AUTHORS   Seki,S., Ohura,K., Miyazaki,T., Naser,A.A., Takabayashi,S.,
            Tsutsumi,E. and Tokumoto,T.
  TITLE     The Mc4r gene is responsible for the development of experimentally
            induced testicular teratomas
  JOURNAL   Sci Rep 13 (1), 6756 (2023)
   PUBMED   37127675
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1490)
  AUTHORS   Bustamante-Marin,X.M. and Capel,B.
  TITLE     Oxygen availability influences the incidence of testicular teratoma
            in Dnd1Ter/+ mice
  JOURNAL   Front Genet 14, 1179256 (2023)
   PUBMED   37180974
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1490)
  AUTHORS   Imai,A., Matsuda,K., Niimi,Y. and Suzuki,A.
  TITLE     Loss of Dead end1 induces testicular teratomas from primordial germ
            cells that failed to undergo sexual differentiation in embryonic
            testes
  JOURNAL   Sci Rep 13 (1), 6398 (2023)
   PUBMED   37076592
  REMARK    GeneRIF: Loss of Dead end1 induces testicular teratomas from
            primordial germ cells that failed to undergo sexual differentiation
            in embryonic testes.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1490)
  AUTHORS   Gu,X., Heinrich,A., Li,S.Y. and DeFalco,T.
  TITLE     Testicular macrophages are recruited during a narrow fetal time
            window and promote organ-specific developmental functions
  JOURNAL   Nat Commun 14 (1), 1439 (2023)
   PUBMED   36922518
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 1490)
  AUTHORS   Sakurai,T., Katoh,H., Moriwaki,K., Noguchi,T. and Noguchi,M.
  TITLE     The ter primordial germ cell deficiency mutation maps near Grl-1 on
            mouse chromosome 18
  JOURNAL   Mamm Genome 5 (6), 333-336 (1994)
   PUBMED   8043946
REFERENCE   7  (bases 1 to 1490)
  AUTHORS   Asada,Y., Varnum,D.S., Frankel,W.N. and Nadeau,J.H.
  TITLE     A mutation in the Ter gene causing increased susceptibility to
            testicular teratomas maps to mouse chromosome 18
  JOURNAL   Nat Genet 6 (4), 363-368 (1994)
   PUBMED   8054975
REFERENCE   8  (bases 1 to 1490)
  AUTHORS   Noguchi,T. and Noguchi,M.
  TITLE     A recessive mutation (ter) causing germ cell deficiency and a high
            incidence of congenital testicular teratomas in 129/Sv-ter mice
  JOURNAL   J Natl Cancer Inst 75 (2), 385-392 (1985)
   PUBMED   3860691
REFERENCE   9  (bases 1 to 1490)
  AUTHORS   Staats,J.
  TITLE     Standardized Nomenclature for Inbred Strains of Mice: eighth
            listing
  JOURNAL   Cancer Res 45 (3), 945-977 (1985)
   PUBMED   3971387
REFERENCE   10 (bases 1 to 1490)
  AUTHORS   Stevens,L.C.
  TITLE     A new inbred subline of mice (129-terSv) with a high incidence of
            spontaneous congenital testicular teratomas
  JOURNAL   J Natl Cancer Inst 50 (1), 235-242 (1973)
   PUBMED   4692863
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC034897.1 and AY321066.1.
            
            On Oct 1, 2008 this sequence version replaced NM_173383.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY321066.1, SRR1660825.222158.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164143 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-48                BC034897.1         1-48
            49-1107             AY321066.1         1-1059
            1108-1490           BC034897.1         1443-1825
FEATURES             Location/Qualifiers
     source          1..1490
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="18"
                     /map="18 19.46 cM"
     gene            1..1490
                     /gene="Dnd1"
                     /gene_synonym="RBMS4; Ter"
                     /note="DND microRNA-mediated repression inhibitor 1"
                     /db_xref="GeneID:213236"
                     /db_xref="MGI:MGI:2447763"
     exon            1..72
                     /gene="Dnd1"
                     /gene_synonym="RBMS4; Ter"
                     /inference="alignment:Splign:2.1.0"
     CDS             49..1107
                     /gene="Dnd1"
                     /gene_synonym="RBMS4; Ter"
                     /note="dead end homolog 1; RNA-binding motif,
                     single-stranded-interacting protein 4; teratoma"
                     /codon_start=1
                     /product="dead end protein homolog 1"
                     /protein_id="NP_775559.2"
                     /db_xref="CCDS:CCDS29163.2"
                     /db_xref="GeneID:213236"
                     /db_xref="MGI:MGI:2447763"
                     /translation="MQSKRECEQWCERVNPENKAALEAWVRETGIRLVQVNGQRKYGG
                     PPPGWVGSPPPSGSEVYIGRLPQDVYEHQLIPLFQRVGRLYEFRLMMTFSGLNRGFAY
                     ARYSSRRGAQAAIATLHNHQLRPSCQLLVCRSTEKCELTVDGLPLSLNRRALLLALQP
                     FGPCLQETLLLPSPGSAPSQIALLKFSTHRAAAMAKKALVEGQSRLCGEQVAVEWLKP
                     DLKQHFRQQLAGPSLRFLRPDVSQLTQTREKLGSQGARAALQLLCQRMKLGSPVFLTK
                     CLGTGPAGWHRFWYQVVIPGHPVPFSGLIWVVLASDWQDGHEVAKDAVSAQLLEALSE
                     PRTSLWSPGAEAGTMVKQ"
     exon            73..190
                     /gene="Dnd1"
                     /gene_synonym="RBMS4; Ter"
                     /inference="alignment:Splign:2.1.0"
     exon            191..652
                     /gene="Dnd1"
                     /gene_synonym="RBMS4; Ter"
                     /inference="alignment:Splign:2.1.0"
     exon            653..1469
                     /gene="Dnd1"
                     /gene_synonym="RBMS4; Ter"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1449..1454
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Dnd1"
                     /gene_synonym="RBMS4; Ter"
                     /note="hexamer: ATTAAA"
     polyA_site      1469
                     /gene="Dnd1"
                     /gene_synonym="RBMS4; Ter"
                     /note="major polyA site"
ORIGIN      
        1 agccgaaaga aggtctaaag agggaactgt aagactttgg aaagagctat gcagtccaaa
       61 cgggagtgcg agcaatggtg tgagagggtg aatccagaga acaaggcagc cctggaggcg
      121 tgggtaaggg agactggcat ccgcctggtg caggtcaacg ggcaaaggaa gtatggaggg
      181 ccacccccag gctgggtggg cagcccgcca ccgtcagggt ccgaggtgta tatcggacga
      241 cttccgcagg acgtgtacga gcaccagcta atcccactct tccagcgcgt ggggcgcctc
      301 tatgagttcc gcctaatgat gaccttcagt ggtttgaacc gcggctttgc ctatgcgcgc
      361 tacagctcgc ggcgcggtgc ccaggccgcc attgctacgc tgcacaacca ccagctgcgg
      421 ccttcttgcc agctcctggt gtgccgaagc accgagaagt gcgagctgac ggtggacggg
      481 ctgcctctta gcttaaaccg ccgagcgtta ctgctcgccc tgcaaccgtt cggtccctgc
      541 ctccaggaga cactgctgct acccagccct gggtctgcgc cctctcagat tgcgctgctc
      601 aagttcagta cgcaccgagc tgctgctatg gccaaaaagg ccctggtaga aggtcagtca
      661 cgcctctgtg gagagcaggt ggctgtggag tggctcaagc cagacctaaa gcagcacttc
      721 cgccagcagc ttgcaggtcc ctcactgcgg ttcctcaggc cagatgtcag ccaactaacc
      781 cagaccaggg agaagctggg gtcccaaggg gctcgggctg ccctgcaact gctgtgtcaa
      841 cggatgaagc taggcagccc agtgttcctg accaagtgtt taggaacagg gcctgctggc
      901 tggcatcgct tttggtacca ggtggtgatc cctgggcatc cagtgccttt cagtggcctc
      961 atttgggttg tgttggcctc tgattggcag gatgggcatg aggtggccaa ggatgctgtg
     1021 tccgcacagc tgctggaggc actgagtgaa cctaggacca gcttgtggtc tcctggggct
     1081 gaagcaggta ctatggttaa gcagtgaccc cttcttttta caggtaccct aaatgggtta
     1141 agcagagcct gtgccaaccc cccagcccag caggcctggg cagcccaggg cctggtgaca
     1201 gctttccctg ctgggacagg gccctgttgc acctaagtgc tactttagtt gtgaggaacc
     1261 ttgccctccc ccactgagcc cagggtctga cctgctatcc ttagtcaatt cccagcttgg
     1321 caccagagct tactatgaat ctttgttttt atttggagaa ctggctgaac caaagagccc
     1381 ttcctcccac cacttgtccc tggtttgggc ttacatggtt tttgtttttc tatactggtt
     1441 ttatttatat taaaacccca gttggtataa aaaaaaaaaa aaaaaaaaaa
//
