LOCUS       NM_153082               4713 bp    mRNA    linear   ROD 10-FEB-2025
DEFINITION  Mus musculus DnaJ heat shock protein family (Hsp40) member C27
            (Dnajc27), mRNA.
ACCESSION   NM_153082
VERSION     NM_153082.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4713)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 4713)
  AUTHORS   Chen,T., Yang,M., Yu,Z., Tang,S., Wang,C., Zhu,X., Guo,J., Li,N.,
            Zhang,W., Hou,J., Liu,H., Han,C., Liu,Q., Gu,Y., Qian,C., Wan,T.,
            Cui,L., Zhu,M., Zheng,W. and Cao,X.
  TITLE     Small GTPase RBJ mediates nuclear entrapment of MEK1/MEK2 in tumor
            progression
  JOURNAL   Cancer Cell 25 (5), 682-696 (2014)
   PUBMED   24746703
  REMARK    GeneRIF: these data suggest that RBJ may be an oncogenic
            Ras-related small GTPase mediating nuclear accumulation of active
            MEK1/MEK2 in tumor progression.
            Erratum:[Cancer Cell. 2021 Mar 8;39(3):438-440. doi:
            10.1016/j.ccell.2021.02.010.. PMID: 33689704]
REFERENCE   3  (bases 1 to 4713)
  AUTHORS   Lau,N.C., Seto,A.G., Kim,J., Kuramochi-Miyagawa,S., Nakano,T.,
            Bartel,D.P. and Kingston,R.E.
  TITLE     Characterization of the piRNA complex from rat testes
  JOURNAL   Science 313 (5785), 363-367 (2006)
   PUBMED   16778019
REFERENCE   4  (bases 1 to 4713)
  AUTHORS   Girard,A., Sachidanandam,R., Hannon,G.J. and Carmell,M.A.
  TITLE     A germline-specific class of small RNAs binds mammalian Piwi
            proteins
  JOURNAL   Nature 442 (7099), 199-202 (2006)
   PUBMED   16751776
REFERENCE   5  (bases 1 to 4713)
  AUTHORS   Nepomuceno-Silva,J.L., de Melo,L.D., Mendonca,S.M., Paixao,J.C. and
            Lopes,U.G.
  TITLE     RJLs: a new family of Ras-related GTP-binding proteins
  JOURNAL   Gene 327 (2), 221-232 (2004)
   PUBMED   14980719
REFERENCE   6  (bases 1 to 4713)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CT572999.10 and CB247441.1.
            
            On Jul 3, 2010 this sequence version replaced NM_153082.3.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC051140.1, SRR1660821.78591.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-286               CT572999.10        149454-149739       c
            287-955             CB247441.1         1-669
            956-4713            CT572999.10        121701-125458       c
FEATURES             Location/Qualifiers
     source          1..4713
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="12"
                     /map="12 1.99 cM"
     gene            1..4713
                     /gene="Dnajc27"
                     /gene_synonym="C330021A05Rik; Rabj; Rbj"
                     /note="DnaJ heat shock protein family (Hsp40) member C27"
                     /db_xref="GeneID:217378"
                     /db_xref="MGI:MGI:2443036"
     exon            1..300
                     /gene="Dnajc27"
                     /gene_synonym="C330021A05Rik; Rabj; Rbj"
                     /inference="alignment:Splign:2.1.0"
     CDS             214..1035
                     /gene="Dnajc27"
                     /gene_synonym="C330021A05Rik; Rabj; Rbj"
                     /EC_number="4.6.1.1"
                     /note="rab and DnaJ domain-containing protein; rab and
                     DnaJ domain containing; Rab-related GTP-binding protein;
                     DnaJ (Hsp40) homolog, subfamily C, member 27"
                     /codon_start=1
                     /product="dnaJ homolog subfamily C member 27"
                     /protein_id="NP_694722.2"
                     /db_xref="CCDS:CCDS25786.1"
                     /db_xref="GeneID:217378"
                     /db_xref="MGI:MGI:2443036"
                     /translation="METNVPKRKEPAKSLRIKVISMGNAEVGKSCIIKRYCEKRFVSK
                     YLATIGIDYGVTKVQVRDREIKVNIFDMAGHPFFFEVRNEFYKDTQGVILVYDVGQKD
                     SFDALDSWLAEMKQELGPHGNMDNIVFVVCANKIDCSKHRCIDESEGRLWAESKGFLY
                     FETSAQTGEGINEMFQTFYLSIVDLCENGGKRPTASSSASFTKEQADTIRRIRNSKDS
                     WEMLGVRPGASREEVNKAYRKLAVLLHPDKCVAPGSEDAFKAVVNARTALLKNIK"
     exon            301..383
                     /gene="Dnajc27"
                     /gene_synonym="C330021A05Rik; Rabj; Rbj"
                     /inference="alignment:Splign:2.1.0"
     exon            384..453
                     /gene="Dnajc27"
                     /gene_synonym="C330021A05Rik; Rabj; Rbj"
                     /inference="alignment:Splign:2.1.0"
     exon            454..618
                     /gene="Dnajc27"
                     /gene_synonym="C330021A05Rik; Rabj; Rbj"
                     /inference="alignment:Splign:2.1.0"
     exon            619..741
                     /gene="Dnajc27"
                     /gene_synonym="C330021A05Rik; Rabj; Rbj"
                     /inference="alignment:Splign:2.1.0"
     exon            742..902
                     /gene="Dnajc27"
                     /gene_synonym="C330021A05Rik; Rabj; Rbj"
                     /inference="alignment:Splign:2.1.0"
     exon            903..4713
                     /gene="Dnajc27"
                     /gene_synonym="C330021A05Rik; Rabj; Rbj"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4689..4694
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Dnajc27"
                     /gene_synonym="C330021A05Rik; Rabj; Rbj"
                     /note="hexamer: AGTAAA"
     polyA_site      4707
                     /gene="Dnajc27"
                     /gene_synonym="C330021A05Rik; Rabj; Rbj"
                     /note="major polyA site"
ORIGIN      
        1 agtcatcgcg agactccgct cgccctccgc ggctcgccgc ttcccaaccg ccctcgtccg
       61 tccgcggcca ggcagcggtg gggatggcga gccgcggagc cagggtggtg acgagcacag
      121 cggctccgtc attgggcgag gaggcctgag ggactccagg ctggctgggt gcgtaaggac
      181 accacaaccc gcggccccgg cagagcgagg gcgatggaga ccaacgtgcc gaagaggaag
      241 gagcccgcca agtccctccg catcaaagtc atctccatgg gcaacgccga agtggggaaa
      301 agctgtatta taaagcgcta ctgtgagaag agatttgtgt ctaaatacct ggcaaccatc
      361 gggattgact atggagtcac aaaggtccaa gtcagagaca gagagatcaa agttaacatc
      421 tttgacatgg ctggacatcc cttcttcttt gaggtccgaa atgagtttta caaggacaca
      481 caaggtgtga tactagtcta tgatgttgga cagaaagact catttgatgc ccttgattcg
      541 tggctggcag agatgaagca ggagcttggg cctcacggga acatggacaa cattgtcttt
      601 gttgtttgtg ccaacaagat cgactgctcc aaacaccgct gcatcgatga aagtgagggg
      661 cgtctctggg ctgaaagcaa agggttcctg tactttgaaa catcagcaca aactggagag
      721 ggaatcaacg agatgttcca gaccttttac ttgtccatag ttgacttgtg tgaaaatggc
      781 gggaagcgtc ctactgcaag tagcagtgct agtttcacca aagaacaagc agacactatt
      841 cgcagaatcc gaaatagtaa ggacagctgg gagatgctag gagtcagacc tggagcctca
      901 agggaggaag ttaataaggc ctaccggaag ctggctgtgc tgcttcaccc ggacaagtgt
      961 gtagcaccag gcagtgaaga tgccttcaaa gcagttgtga atgcccggac agccctcctg
     1021 aaaaacatca agtagaggca gaggaaacta caagcgagct caagtgcaaa cagactcccc
     1081 ttgaggtgaa ataaccaaca tggagttttc cttcacgaat gctcactgtt gtgttccctc
     1141 atgtgtaagt taatagtatg ggtgcctgtt accatgttgt ggccatttct cagtgagatg
     1201 accgcttttg tgtgagagat aaccccacat ctcttatgca cttcatttct tattgccaga
     1261 taactaggtg tttgtcattg tgtcatcgct tatgcattca cctgtgaaag tccatgactg
     1321 tgacccacct gctcttcctc ccagcaaccc tccatccatc catctgccca ccatcagaga
     1381 aaggaataac aacaggagag agaaagagcc tggcccccgg gagcctgcac cccactaagc
     1441 ggcttcctgg ttagtatttt aaccatcagc ctgtacagtt agtagccaga gatggtggag
     1501 gatgaggcag gagtattgca agagagaggc cagtctggat tgaattactt ggcaagactt
     1561 tcaaagaaaa acaggcaacc ttgtagaaga gtgatgtgag ctagcactgt tatctgccct
     1621 tttaggacac tgactctgtt ctttctccag ccaccagggg gagacaagcc agtgctaaga
     1681 gagaggcagt gccagccaca ggagctggag aacctgaagc tcatcccgga tcccaggcct
     1741 ttgctctgcc ctagaaatag ttgctagcat caagcagcaa ggatgctgtg tccctgggaa
     1801 tgaggggccc gacaccagaa cagaagctct tagagggcgc attgtgggtc acttgggagt
     1861 gtgcgctcag tcacaccatt cagacggaaa ggccagcttg ggcctttcct gagctcaggc
     1921 atgttgggca ctaggaggga ccctgcatga gactcgtccc tgtcctcagt cctcaccaca
     1981 ggtggtggga gaggcaggcg ggccctcttc cacagacccg tctctttctt ctgctctcct
     2041 ctcgccccac tctttgttac atcccacatc tgccatggcc tttcctcttg ccctgggctc
     2101 agctgacttg aaataagtag gatccatttg gggcacactg ggacgtcttg ggcctgtgtg
     2161 gggcagaatc cctacagttt ctgcttggac tccaaatttc tgaatagtat tttaaaatta
     2221 caagtatgaa aactcatgtt gcatagagag aagcctttct cgtgctgttg cccctgcctg
     2281 gtccacagga ctggatggag ctgatggagc tgggctcatg ttgctcgact cctgtcatcc
     2341 ctctgaactc tggtattctt attttgagct gcagccacct gtgctacctg gaactcaaag
     2401 gatgactttt aaatacctat cccataacgg ttgccagata acatgtctct tgcctaagaa
     2461 gacaagctct tggcttcctg tctaaaccct tgtagtcctc tgggtttttc ctttctccat
     2521 agtggcctca ctttgcatgg ctgtgctctg cgcagctgct ctgagcttta aaatgttgtt
     2581 cttagtgaac tcagatgtgt ataaaaggat aaagaggtct ggcatacggc tgtattagca
     2641 tacggctgcg tggcttgaat tagcttctga ggtgattgag ctccacctca tggttctcat
     2701 gggcctcagt tctgcttgag gctccctcac gcctagcaca tctgattatc cagctgctcc
     2761 tggaacagaa agtgggagtc atgaggatga gaggtgtgtg tggtgctgtc agcctgagtg
     2821 cggggcccag gctgcgcctc gttcaaccac atgggcagga gagcagttac agcagggggc
     2881 tttagtgttc ccatttgggt ccctcaggtc acttgctgat tctcagatct tgagacgctg
     2941 ttcctgacat cttacttata tctagggtgg ctgcgtagca tcttatttat ttatttattt
     3001 atgtaagagt aataaaatga agaggtgaag cctcagggtc ccagaatgtg tctggtttct
     3061 ttagtctctc agcagagcat taggaaacaa cagagcatag ctcagaacga aaagtattct
     3121 gaaccctggc ttcgtgatcc ggtacagacc tctgcattca ttgaaattct tagtgcagct
     3181 gtgtgctttg tccttcgaca ttttgaaaac tgcttgcaca tttaagatct taggacgtca
     3241 gcaggagtct caactcagtc atttcagagg ctgaaacgtt tttataaaga accttgcccc
     3301 cccccaaaaa aaagaaggga taaaatattt gaacaactgt tatcttaaaa agctgtgtcc
     3361 ttctccatct gagtcaccaa ctggtgtcac ctcttcactt gttggaagtc cctggaggca
     3421 tttctgagtt cgtcttccag ccttcgtcag cactttagag cgtcctcccc tcccctggtg
     3481 tgtgctctcc tctgtgtctc cctggagctg ctgggctcca ctctcagtgt ctctctaacc
     3541 ccggagctac tgggctctgc tctcagtgtc tctatcccgg gagctgctgg gctctgctct
     3601 cagtgtctct ctatcctggg agctactggg ctctgctctc agtgtctcta tcctgggagc
     3661 tgctggactc cgctctcagt gtctctctac gcactgccgc tttacttctc catgtcaatg
     3721 tcgtctgtgg ctttgccagc atcttaactc acgagtccag atgctgagag taaggctgct
     3781 gtccttctgc acactgtaca ccattcttta aggcttgtat ttacctcagg aaacatattc
     3841 tagtatcttc tcactgattg aaatctcaag tgataaatac ttctttatac ctgcaaaatg
     3901 gtacctattt ctgtcttagt tcggtgagca gctagatggt caggtatcta gatggtcagg
     3961 tacctatttc tgtcttagtt cggtcaggca gctagatggt caggtatcta aatggctgaa
     4021 agctcgtcag agtaggacaa ggggctcctg ccagcactga atcggggaca agtggtagaa
     4081 agacagaggg attgccattt gaagctagga agcaaggagc cagcatatcg cctctagcaa
     4141 tgacagtgat cccttccagg tcagctcagt aggttctctc atgctgcctc ccatggagct
     4201 aagtccccag cgtttttgta aaccttttga agatgaattt agttgcaaaa tcaagctaag
     4261 caatttccac ttcaggcttt gcaagcaaag agctattgct ccttctcatc ctggtgctga
     4321 gcacagtttt agacctggtt agtgcccttg gacattgatt gctccattaa ctgtccctga
     4381 ggagggtgga tgtgtttact tgtggtatgg gcaggcagtg ggtctgtgtc ttaacacaca
     4441 gtgcggtgct gggcagtctg gagaaggccc ttggtgaaag gctgttactg aagagttgga
     4501 cagtttgggt tagctccctg cactggtgct gaccgctccc tgcacattct ttccctccac
     4561 tgtgaatgct cgtacaaggt aatttacata tttgctttct gttgaaataa ctgaaagtgt
     4621 taaatctacc agttgtttat gtcttgtata cagagtgtca tatgtattta agttgtgtat
     4681 ttttatagag taaagtcaaa tagcaaacac tgg
//
