LOCUS       NM_026992               1198 bp    mRNA    linear   ROD 30-JUL-2024
DEFINITION  Mus musculus DnaJ heat shock protein family (Hsp40) member C24
            (Dnajc24), transcript variant 1, mRNA.
ACCESSION   NM_026992
VERSION     NM_026992.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1198)
  AUTHORS   Favor,J., Bradley,A., Conte,N., Janik,D., Pretsch,W., Reitmeir,P.,
            Rosemann,M., Schmahl,W., Wienberg,J. and Zaus,I.
  TITLE     Analysis of Pax6 contiguous gene deletions in the mouse, Mus
            musculus, identifies regions distinct from Pax6 responsible for
            extreme small-eye and belly-spotting phenotypes
  JOURNAL   Genetics 182 (4), 1077-1088 (2009)
   PUBMED   19474196
REFERENCE   2  (bases 1 to 1198)
  AUTHORS   Webb,T.R., Cross,S.H., McKie,L., Edgar,R., Vizor,L., Harrison,J.,
            Peters,J. and Jackson,I.J.
  TITLE     Diphthamide modification of eEF2 requires a J-domain protein and is
            essential for normal development
  JOURNAL   J Cell Sci 121 (Pt 19), 3140-3145 (2008)
   PUBMED   18765564
  REMARK    GeneRIF: A mouse that was mutant for the gene, Dph4, was
            identified.
REFERENCE   3  (bases 1 to 1198)
  AUTHORS   Kroczynska,B. and Blond,S.Y.
  TITLE     Cloning and characterization of a new soluble murine J-domain
            protein that stimulates BiP, Hsc70 and DnaK ATPase activity with
            different efficiencies
  JOURNAL   Gene 273 (2), 267-274 (2001)
   PUBMED   11595173
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK006521.1 and AV331303.1.
            
            On Jul 7, 2010 this sequence version replaced NM_026992.2.
            
            Transcript Variant: This variant (1) encodes the functional
            protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK006521.1, BC030072.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164134, SAMN01164135
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1189              AK006521.1         2-1190
            1190-1198           AV331303.1         294-302
FEATURES             Location/Qualifiers
     source          1..1198
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 55.46 cM"
     gene            1..1198
                     /gene="Dnajc24"
                     /gene_synonym="1700030A21Rik; 2610027M02Rik; Dph4; MmDjC7;
                     Zcsl3"
                     /note="DnaJ heat shock protein family (Hsp40) member C24"
                     /db_xref="GeneID:99349"
                     /db_xref="MGI:MGI:1919522"
     exon            1..456
                     /gene="Dnajc24"
                     /gene_synonym="1700030A21Rik; 2610027M02Rik; Dph4; MmDjC7;
                     Zcsl3"
                     /inference="alignment:Splign:2.1.0"
     exon            457..603
                     /gene="Dnajc24"
                     /gene_synonym="1700030A21Rik; 2610027M02Rik; Dph4; MmDjC7;
                     Zcsl3"
                     /inference="alignment:Splign:2.1.0"
     CDS             496..942
                     /gene="Dnajc24"
                     /gene_synonym="1700030A21Rik; 2610027M02Rik; Dph4; MmDjC7;
                     Zcsl3"
                     /note="zinc finger, CSL-type containing 3; j domain
                     protein DjC7; CSL-type zinc finger-containing protein 3;
                     DPH4 homolog (JJJ3, S. cerevisiae); diphthamide
                     biosynthesis protein 4; DnaJ (Hsp40) homolog, subfamily C,
                     member 24"
                     /codon_start=1
                     /product="dnaJ homolog subfamily C member 24"
                     /protein_id="NP_081268.1"
                     /db_xref="CCDS:CCDS16501.1"
                     /db_xref="GeneID:99349"
                     /db_xref="MGI:MGI:1919522"
                     /translation="MALEQTLKKDWYSILGADPSANMSDLKQKYQKLILLYHPDKQSA
                     DVPAGTMEECMQKFIEIDQAWKILGNEETKKKYDLQRHEDELRNVGPVDAQVRLEEMS
                     WNQGDESFFLSCRCGGKYTVSKDEAQEATLISCDACSLIVELLHQS"
     exon            604..742
                     /gene="Dnajc24"
                     /gene_synonym="1700030A21Rik; 2610027M02Rik; Dph4; MmDjC7;
                     Zcsl3"
                     /inference="alignment:Splign:2.1.0"
     exon            743..811
                     /gene="Dnajc24"
                     /gene_synonym="1700030A21Rik; 2610027M02Rik; Dph4; MmDjC7;
                     Zcsl3"
                     /inference="alignment:Splign:2.1.0"
     exon            812..1198
                     /gene="Dnajc24"
                     /gene_synonym="1700030A21Rik; 2610027M02Rik; Dph4; MmDjC7;
                     Zcsl3"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1100..1105
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Dnajc24"
                     /gene_synonym="1700030A21Rik; 2610027M02Rik; Dph4; MmDjC7;
                     Zcsl3"
                     /note="hexamer: AATAAT"
     polyA_site      1125
                     /gene="Dnajc24"
                     /gene_synonym="1700030A21Rik; 2610027M02Rik; Dph4; MmDjC7;
                     Zcsl3"
     regulatory      1174..1179
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Dnajc24"
                     /gene_synonym="1700030A21Rik; 2610027M02Rik; Dph4; MmDjC7;
                     Zcsl3"
                     /note="hexamer: TATAAA"
     polyA_site      1197
                     /gene="Dnajc24"
                     /gene_synonym="1700030A21Rik; 2610027M02Rik; Dph4; MmDjC7;
                     Zcsl3"
                     /note="major polyA site"
ORIGIN      
        1 ttgctcaagg taaagtaaga ggaacctagg atgaaggtgc accttaggag atgtagaggg
       61 atgcaacaat cgtggtgtcg gggcaaagga agaattagag caaattgagg aaaggcattt
      121 ctctgcgtac ctctcactgt tgacaaaacc tcagaaatcc cgacgcgtta ccatagcggc
      181 cgcgtctgga ctggaggcgg ggcctttcag taatgtgcac caacaactag ggcgcgactg
      241 gaaacgtact cccgctgtac tccaacttcc ggcggaaaag aaagtgggtt ccgctttccg
      301 tccggctgcc gcagcaagtg gactcctgct ccaaagtgaa gcgccataag tctgacgctg
      361 tgtggagcca ggggaaggca tcagcaggga cagcctcggt ggggcggacg cctgcctgtg
      421 gacgccgcgt gtccgccaag ctgcggctgc ttcagggtca tcagagaagg ctcccttcta
      481 ggtcaaagga cgctgatggc tttggagcag acactcaaaa aggattggta cagcattctg
      541 ggtgcagacc catctgcaaa tatgtcagac ctaaaacaaa aatatcagaa actcatatta
      601 ctgtatcatc cagataaaca aagtgcagat gtgccagctg gaaccatgga ggagtgtatg
      661 cagaagttta ttgaaattga tcaggcatgg aaaattctag ggaatgaaga aaccaagaaa
      721 aagtatgacc tgcagcggca tgaagatgag ctaagaaatg tggggccagt agatgcacag
      781 gtgcgccttg aagagatgtc ctggaaccaa ggtgatgaat ctttctttct gagctgtcga
      841 tgtggtggga aatacactgt ctccaaggat gaagcacaag aagccaccct catctcctgt
      901 gacgcgtgct cgctgattgt ggagctcctc catcagagct gagctgcgtc ttctgccctc
      961 ggtcctttac aacaaggaca cagatgcttt cttgttattc aagatggtct tcaagcaaaa
     1021 ccacttaaga ttaacaaatt aattcagttt tttatatgta tctaaaatgt aaattatagg
     1081 atattacaag aaggacttga ataatatttt tgcactttta gctaacaact tttgttttct
     1141 ctttggtaca aactaatgat ttcctttttg aagtataaat atctttttca aaaatcag
//
