LOCUS       NM_139139               1026 bp    mRNA    linear   ROD 10-FEB-2025
DEFINITION  Mus musculus DnaJ heat shock protein family (Hsp40) member C17
            (Dnajc17), mRNA.
ACCESSION   NM_139139
VERSION     NM_139139.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1026)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1026)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24643.. PMID: 29144450]
REFERENCE   3  (bases 1 to 1026)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   4  (bases 1 to 1026)
  AUTHORS   Slater,L.H., Hett,E.C., Clatworthy,A.E., Mark,K.G. and Hung,D.T.
  TITLE     CCT chaperonin complex is required for efficient delivery of
            anthrax toxin into the cytosol of host cells
  JOURNAL   Proc Natl Acad Sci U S A 110 (24), 9932-9937 (2013)
   PUBMED   23716698
REFERENCE   5  (bases 1 to 1026)
  AUTHORS   Amendola,E., Sanges,R., Galvan,A., Dathan,N., Manenti,G.,
            Ferrandino,G., Alvino,F.M., Di Palma,T., Scarfo,M., Zannini,M.,
            Dragani,T.A., De Felice,M. and Di Lauro,R.
  TITLE     A locus on mouse chromosome 2 is involved in susceptibility to
            congenital hypothyroidism and contains an essential gene expressed
            in thyroid
  JOURNAL   Endocrinology 151 (4), 1948-1958 (2010)
   PUBMED   20160132
  REMARK    GeneRIF: Dnajc17 is highly expressed in the thyroid bud and had an
            essential function in development, suggesting an important role of
            this protein in organogenesis and/or function of the thyroid gland.
REFERENCE   6  (bases 1 to 1026)
  AUTHORS   Nishimura,M., Yokoi,N., Miki,T., Horikawa,Y., Yoshioka,H.,
            Takeda,J., Ohara,O. and Seino,S.
  TITLE     Construction of a multi-functional cDNA library specific for mouse
            pancreatic islets and its application to microarray
  JOURNAL   DNA Res 11 (5), 315-323 (2004)
   PUBMED   15747579
REFERENCE   7  (bases 1 to 1026)
  AUTHORS   Carninci,P., Waki,K., Shiraki,T., Konno,H., Shibata,K., Itoh,M.,
            Aizawa,K., Arakawa,T., Ishii,Y., Sasaki,D., Bono,H., Kondo,S.,
            Sugahara,Y., Saito,R., Osato,N., Fukuda,S., Sato,K., Watahiki,A.,
            Hirozane-Kishikawa,T., Nakamura,M., Shibata,Y., Yasunishi,A.,
            Kikuchi,N., Yoshiki,A., Kusakabe,M., Gustincich,S., Beisel,K.,
            Pavan,W., Aidinis,V., Nakagawara,A., Held,W.A., Iwata,H., Kono,T.,
            Nakauchi,H., Lyons,P., Wells,C., Hume,D.A., Fagiolini,M.,
            Hensch,T.K., Brinkmeier,M., Camper,S., Hirota,J., Mombaerts,P.,
            Muramatsu,M., Okazaki,Y., Kawai,J. and Hayashizaki,Y.
  TITLE     Targeting a complex transcriptome: the construction of the mouse
            full-length cDNA encyclopedia
  JOURNAL   Genome Res 13 (6B), 1273-1289 (2003)
   PUBMED   12819125
REFERENCE   8  (bases 1 to 1026)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   9  (bases 1 to 1026)
  AUTHORS   Brady,K.P., Rowe,L.B., Her,H., Stevens,T.J., Eppig,J.,
            Sussman,D.J., Sikela,J. and Beier,D.R.
  TITLE     Genetic mapping of 262 loci derived from expressed sequences in a
            murine interspecific cross using single-strand conformational
            polymorphism analysis
  JOURNAL   Genome Res 7 (11), 1085-1093 (1997)
   PUBMED   9371744
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY794890.1, AK077385.1 and BP770408.1.
            
            On Jul 21, 2009 this sequence version replaced NM_139139.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: ERR3835353.259375.1, AK077385.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-42                BY794890.1         2-43
            43-1001             AK077385.1         3-961
            1002-1026           BP770408.1         1-25                c
FEATURES             Location/Qualifiers
     source          1..1026
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 59.97 cM"
     gene            1..1026
                     /gene="Dnajc17"
                     /gene_synonym="1700025B16Rik; D9Bwg1371e"
                     /note="DnaJ heat shock protein family (Hsp40) member C17"
                     /db_xref="GeneID:69408"
                     /db_xref="MGI:MGI:1916658"
     exon            1..108
                     /gene="Dnajc17"
                     /gene_synonym="1700025B16Rik; D9Bwg1371e"
                     /inference="alignment:Splign:2.1.0"
     CDS             31..942
                     /gene="Dnajc17"
                     /gene_synonym="1700025B16Rik; D9Bwg1371e"
                     /note="DnaJ (Hsp40) homolog, subfamily C, member 17"
                     /codon_start=1
                     /product="dnaJ homolog subfamily C member 17"
                     /protein_id="NP_631878.2"
                     /db_xref="CCDS:CCDS16593.1"
                     /db_xref="GeneID:69408"
                     /db_xref="MGI:MGI:1916658"
                     /translation="MAVTKELLQMDLYALLGIEEKAADKEVKKAYRQKALSCHPDKNP
                     DNPRAAELFHQLSQALEVLTDAAARAAYDKVRKAKKQAAERTQRLDENRKKVKLDLEA
                     RERQAQAHGSEEEEESRSATTLEQEIARLREEGSRQLEEQQRLIQEQIRQDREQRLRG
                     RTENTEGKGTPKLKLKWKCKKEDESQGGYSRDVLLRLLQKYGEVLNLVLSRKKAGNAI
                     VEFATVRAAELAVRNEVGLADNPLKVSWLEGQPQSTVDPGPPGLSKGSVLSERDFESL
                     VMMRMRQAAERQQLIAQMQQEDEGRPT"
     exon            109..178
                     /gene="Dnajc17"
                     /gene_synonym="1700025B16Rik; D9Bwg1371e"
                     /inference="alignment:Splign:2.1.0"
     exon            179..237
                     /gene="Dnajc17"
                     /gene_synonym="1700025B16Rik; D9Bwg1371e"
                     /inference="alignment:Splign:2.1.0"
     exon            238..325
                     /gene="Dnajc17"
                     /gene_synonym="1700025B16Rik; D9Bwg1371e"
                     /inference="alignment:Splign:2.1.0"
     exon            326..411
                     /gene="Dnajc17"
                     /gene_synonym="1700025B16Rik; D9Bwg1371e"
                     /inference="alignment:Splign:2.1.0"
     exon            412..508
                     /gene="Dnajc17"
                     /gene_synonym="1700025B16Rik; D9Bwg1371e"
                     /inference="alignment:Splign:2.1.0"
     exon            509..552
                     /gene="Dnajc17"
                     /gene_synonym="1700025B16Rik; D9Bwg1371e"
                     /inference="alignment:Splign:2.1.0"
     exon            553..630
                     /gene="Dnajc17"
                     /gene_synonym="1700025B16Rik; D9Bwg1371e"
                     /inference="alignment:Splign:2.1.0"
     exon            631..711
                     /gene="Dnajc17"
                     /gene_synonym="1700025B16Rik; D9Bwg1371e"
                     /inference="alignment:Splign:2.1.0"
     exon            712..822
                     /gene="Dnajc17"
                     /gene_synonym="1700025B16Rik; D9Bwg1371e"
                     /inference="alignment:Splign:2.1.0"
     exon            823..1008
                     /gene="Dnajc17"
                     /gene_synonym="1700025B16Rik; D9Bwg1371e"
                     /inference="alignment:Splign:2.1.0"
     regulatory      989..994
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Dnajc17"
                     /gene_synonym="1700025B16Rik; D9Bwg1371e"
                     /note="hexamer: AATAAA"
     polyA_site      1008
                     /gene="Dnajc17"
                     /gene_synonym="1700025B16Rik; D9Bwg1371e"
                     /note="major polyA site"
ORIGIN      
        1 gtagtatcaa ttcaagtttg gactagaacc atggcggtga ccaaagagct cttacaaatg
       61 gatctgtacg cgctgctcgg cattgaggag aaggcggcag acaaagaggt gaagaaggcg
      121 tacaggcaaa aagcactatc ctgccaccca gacaaaaatc cagataaccc cagagcagct
      181 gaactcttcc accagctgtc ccaggccttg gaagtgctga cggatgctgc agccagggct
      241 gcatatgaca aggttaggaa agccaagaag caggcagcag agaggaccca gagacttgac
      301 gagaacagga agaaagtgaa acttgatctg gaggccaggg agcggcaggc ccaggcccat
      361 gggagtgagg aagaggagga gagcaggagc gccaccacac tagagcagga gattgctcga
      421 cttcgagaag agggttcccg tcagttggaa gagcagcaga ggctgatcca ggagcagatc
      481 cgccaggacc gagaacagag gctgagagga agaacagaaa atactgaagg caaaggaacc
      541 cccaaactaa agctaaagtg gaagtgcaag aaggaggatg agtcccaagg tggctactcc
      601 agagatgtcc tcctgaggct tttacagaag tatggggagg ttctcaacct ggtactttcc
      661 agaaagaagg caggcaatgc catagtggag tttgcaactg tcagagctgc ggagctggct
      721 gtcagaaatg aagtgggcct ggctgacaac cctctgaagg tttcctggtt ggagggacag
      781 ccccagagca cagtggaccc cggcccccca ggactgtcaa agggctcagt gctgtcagaa
      841 agggactttg agagtctcgt catgatgcgc atgcgccagg cagctgagcg ccagcagctg
      901 attgcccaga tgcagcagga agatgagggg cggcccacgt agccccggct ccagccttcc
      961 caccccacac cctttctgaa tcatcaccaa taaacttttt taaaaacaaa aaaaaaaaaa
     1021 aaaaaa
//
