LOCUS       NM_172338               3913 bp    mRNA    linear   ROD 10-FEB-2025
DEFINITION  Mus musculus DnaJ heat shock protein family (Hsp40) member C16
            (Dnajc16), mRNA.
ACCESSION   NM_172338
VERSION     NM_172338.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3913)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3913)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3913)
  AUTHORS   Sundberg,J.P., Dadras,S.S., Silva,K.A., Kennedy,V.E., Garland,G.,
            Murray,S.A., Sundberg,B.A., Schofield,P.N. and Pratt,C.H.
  TITLE     Systematic screening for skin, hair, and nail abnormalities in a
            large-scale knockout mouse program
  JOURNAL   PLoS One 12 (7), e0180682 (2017)
   PUBMED   28700664
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 3913)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24643.. PMID: 29144450]
REFERENCE   5  (bases 1 to 3913)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   6  (bases 1 to 3913)
  AUTHORS   Willnow,T., Antignac,C., Brandli,A., Christensen,E., Cox,R.,
            Davidson,D., Davies,J., Devuyst,O., Eichele,G., Hastie,N.,
            Verroust,P., Schedl,A. and Meij,I.
  TITLE     The European renal genome project: an integrated approach towards
            understanding the genetics of kidney development and disease
  JOURNAL   Organogenesis 2 (2), 42-47 (2005)
   PUBMED   19521566
REFERENCE   7  (bases 1 to 3913)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Aizawa,H., Yuasa,S.,
            Nakajima,D., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: II. The complete nucleotide sequences of 400 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (1), 35-48 (2003)
   PUBMED   12693553
REFERENCE   8  (bases 1 to 3913)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AL928577.21.
            
            On Mar 21, 2007 this sequence version replaced NM_172338.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK051048.1, AK164023.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-55                AL928577.21        53350-53404         c
            56-240              AL928577.21        51649-51833         c
            241-307             AL928577.21        47448-47514         c
            308-641             AL928577.21        45533-45866         c
            642-826             AL928577.21        39655-39839         c
            827-931             AL928577.21        38126-38230         c
            932-1090            AL928577.21        37261-37419         c
            1091-1221           AL928577.21        33667-33797         c
            1222-1405           AL928577.21        32613-32796         c
            1406-1588           AL928577.21        30651-30833         c
            1589-1665           AL928577.21        30468-30544         c
            1666-1746           AL928577.21        29422-29502         c
            1747-1845           AL928577.21        29244-29342         c
            1846-2016           AL928577.21        27328-27498         c
            2017-3913           AL928577.21        24758-26654         c
FEATURES             Location/Qualifiers
     source          1..3913
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 74.75 cM"
     gene            1..3913
                     /gene="Dnajc16"
                     /gene_synonym="2900037O03Rik; 4732437J24Rik; D030060M24;
                     ERdj8; mKIAA0962"
                     /note="DnaJ heat shock protein family (Hsp40) member C16"
                     /db_xref="GeneID:214063"
                     /db_xref="MGI:MGI:2442146"
     exon            1..55
                     /gene="Dnajc16"
                     /gene_synonym="2900037O03Rik; 4732437J24Rik; D030060M24;
                     ERdj8; mKIAA0962"
                     /inference="alignment:Splign:2.1.0"
     exon            56..240
                     /gene="Dnajc16"
                     /gene_synonym="2900037O03Rik; 4732437J24Rik; D030060M24;
                     ERdj8; mKIAA0962"
                     /inference="alignment:Splign:2.1.0"
     CDS             74..2392
                     /gene="Dnajc16"
                     /gene_synonym="2900037O03Rik; 4732437J24Rik; D030060M24;
                     ERdj8; mKIAA0962"
                     /note="dnaJ homolog subfamily C member 16; DnaJ (Hsp40)
                     homolog, subfamily C, member 16; ER-resident protein
                     ERdj8; endoplasmic reticulum DNA J domain-containing
                     protein 8"
                     /codon_start=1
                     /product="dnaJ homolog subfamily C member 16 precursor"
                     /protein_id="NP_758841.1"
                     /db_xref="CCDS:CCDS18882.1"
                     /db_xref="GeneID:214063"
                     /db_xref="MGI:MGI:2442146"
                     /translation="MELKRLGVSWRFLMVLVLILQSLSALDFDPYRVLGVSRTASQAD
                     IKKAYKKLAREWHPDKNKDPGAEDRFIQISKAYEILSNEEKRTNYDHYGDAGENQGYQ
                     KQQREHRFRHFHENFYFDESFFHFPFNAERRDSGDEKYLLHFSHYVNEVLPESFKRPY
                     LIKITSDWCFSCIHIEPVWKEVVQELEGLGVGIGVVHAGYERRLAHHLGAHSTPSILG
                     VISGKITFFHNAVVHENLRQFVESLLPGNLVEKVTNKNYVRFLSGWQQENKPHALLFG
                     QTPAVPLMYKLTAFAYKDYVSFGYVYVGLRGVEEMTRQYNVNLYTPTMLIFKEHINKP
                     ADVIQARGLKKQVIEDFIAQNKYLLASRLTSQRLFHELCPVKRSHRQRKYCVVLLTAE
                     TNKVSKPFEAFLSFALANTQDTVRFVHVYSNRQQEFASTLLPDMEAFQGKSGVSILER
                     RNTAGRVVFKTLEDPWTGSESDKFVLLGYLDQLRKDPAFLSSEAVLPDLTDELAPVFF
                     LRWLYSVSDYLSDFWESLLHSNWREMMPLLSLIFSALFILFGTVMVQAFSDSNEERES
                     HPADKEEVPEKAGKTEPSFTKESSSKIPKKGFVEVTELTDVTYTSNLVRLRPGHMNVV
                     LILSNSTKTSLLQKFALEVYTFTGSSSLHFSFLTLDKHREWLEYLLEFAQDAAPIPNQ
                     YDKHFMERDYTGYVLALNGHKKYFCLFKPLKTVDEETVASCDPDSSRGKPSCGLGPKP
                     LKGKLSKLSLWMERLLEGSLQRFYIPSWPELD"
     exon            241..307
                     /gene="Dnajc16"
                     /gene_synonym="2900037O03Rik; 4732437J24Rik; D030060M24;
                     ERdj8; mKIAA0962"
                     /inference="alignment:Splign:2.1.0"
     exon            308..641
                     /gene="Dnajc16"
                     /gene_synonym="2900037O03Rik; 4732437J24Rik; D030060M24;
                     ERdj8; mKIAA0962"
                     /inference="alignment:Splign:2.1.0"
     exon            642..826
                     /gene="Dnajc16"
                     /gene_synonym="2900037O03Rik; 4732437J24Rik; D030060M24;
                     ERdj8; mKIAA0962"
                     /inference="alignment:Splign:2.1.0"
     exon            827..931
                     /gene="Dnajc16"
                     /gene_synonym="2900037O03Rik; 4732437J24Rik; D030060M24;
                     ERdj8; mKIAA0962"
                     /inference="alignment:Splign:2.1.0"
     exon            932..1090
                     /gene="Dnajc16"
                     /gene_synonym="2900037O03Rik; 4732437J24Rik; D030060M24;
                     ERdj8; mKIAA0962"
                     /inference="alignment:Splign:2.1.0"
     exon            1091..1221
                     /gene="Dnajc16"
                     /gene_synonym="2900037O03Rik; 4732437J24Rik; D030060M24;
                     ERdj8; mKIAA0962"
                     /inference="alignment:Splign:2.1.0"
     exon            1222..1405
                     /gene="Dnajc16"
                     /gene_synonym="2900037O03Rik; 4732437J24Rik; D030060M24;
                     ERdj8; mKIAA0962"
                     /inference="alignment:Splign:2.1.0"
     exon            1406..1588
                     /gene="Dnajc16"
                     /gene_synonym="2900037O03Rik; 4732437J24Rik; D030060M24;
                     ERdj8; mKIAA0962"
                     /inference="alignment:Splign:2.1.0"
     exon            1589..1665
                     /gene="Dnajc16"
                     /gene_synonym="2900037O03Rik; 4732437J24Rik; D030060M24;
                     ERdj8; mKIAA0962"
                     /inference="alignment:Splign:2.1.0"
     exon            1666..1746
                     /gene="Dnajc16"
                     /gene_synonym="2900037O03Rik; 4732437J24Rik; D030060M24;
                     ERdj8; mKIAA0962"
                     /inference="alignment:Splign:2.1.0"
     exon            1747..1845
                     /gene="Dnajc16"
                     /gene_synonym="2900037O03Rik; 4732437J24Rik; D030060M24;
                     ERdj8; mKIAA0962"
                     /inference="alignment:Splign:2.1.0"
     exon            1846..2016
                     /gene="Dnajc16"
                     /gene_synonym="2900037O03Rik; 4732437J24Rik; D030060M24;
                     ERdj8; mKIAA0962"
                     /inference="alignment:Splign:2.1.0"
     exon            2017..3913
                     /gene="Dnajc16"
                     /gene_synonym="2900037O03Rik; 4732437J24Rik; D030060M24;
                     ERdj8; mKIAA0962"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2504..2509
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Dnajc16"
                     /gene_synonym="2900037O03Rik; 4732437J24Rik; D030060M24;
                     ERdj8; mKIAA0962"
                     /note="hexamer: AGTAAA"
     polyA_site      2529
                     /gene="Dnajc16"
                     /gene_synonym="2900037O03Rik; 4732437J24Rik; D030060M24;
                     ERdj8; mKIAA0962"
ORIGIN      
        1 ggcggattca ctggagcacg gacgctgcgg ccggttgggc cggtgccctt tcccgctctg
       61 ggaaggaaga gagatggaat tgaaaaggtt gggcgtgtcc tggcgattct tgatggttct
      121 ggttctgatc ctgcaaagcc tgtctgcatt ggattttgac ccatacagag tcctaggggt
      181 cagccgcacg gccagtcagg ctgacattaa aaaggcatat aagaagctcg ctcgggaatg
      241 gcatcctgac aaaaacaaag accctggagc cgaggacagg ttcattcaga tcagcaaggc
      301 atacgagatc ctgtccaatg aggaaaagag gacaaactac gaccactatg gtgatgccgg
      361 tgagaaccaa ggctaccaga agcagcagcg cgaacaccgc ttccgccatt tccacgagaa
      421 cttctatttt gatgagtcct ttttccactt ccccttcaat gcggagcggc gggactcggg
      481 tgacgagaag tacttgctgc acttctcaca ctacgtgaat gaagtgcttc ccgagagctt
      541 caaaagaccc tacctcatca agatcacgtc agactggtgc ttcagctgca tccatatcga
      601 gcctgtctgg aaggaggtgg tccaggaact ggaaggactg ggtgtgggga ttggtgtcgt
      661 ccacgctggg tacgaaaggc gcctggccca tcacctggga gcacacagca ccccctccat
      721 ccttggggtc atcagtggga agatcacctt cttccacaac gcagtggtcc atgaaaacct
      781 acggcagttc gtggagagtc ttctcccagg aaacttggta gagaaggtca caaataaaaa
      841 ttatgtgcgg ttcctctctg gctggcagca ggagaataag ccacacgccc tcctgttcgg
      901 ccagacacca gcagtgccac tgatgtacaa gttgacggcc ttcgcataca aggattatgt
      961 gtcgtttgga tacgtgtatg tcggcttgag aggtgtggaa gagatgacca ggcagtacaa
     1021 cgtcaacctc tataccccca ccatgctcat cttcaaagag cacataaaca agcccgctga
     1081 tgtgatccag gctcggggac tgaagaagca ggtcatcgag gacttcatcg cccaaaacaa
     1141 gtacctgctg gcctcccggc tcaccagcca gaggttgttc catgaactct gccctgtgaa
     1201 gcggtctcac cgacagagaa aatactgcgt ggttttactg acagctgaga ctaacaaagt
     1261 gagcaaaccc tttgaagcct tcctgtcatt tgccctggca aacactcaag acacggtacg
     1321 gttcgtgcat gtctacagca accgacagca ggagtttgcc agcacattgc taccggacat
     1381 ggaagctttc caggggaagt caggggtgtc catcttggaa aggaggaaca cagcggggag
     1441 ggtggtgttc aaaaccctgg aggatccctg gaccggcagt gagagcgata agttcgtcct
     1501 tttgggttat cttgaccagc tgcggaagga tccagcattt ctgtcttcag aagctgtgct
     1561 ccctgacctg actgacgagc tggctcctgt atttttcctc cggtggctct actctgtttc
     1621 tgactacctc tcggacttct gggagagcct gcttcacagt aactggcggg agatgatgcc
     1681 cctgctgtcc ctcatcttct cggccctctt catcctcttc ggcacggtca tggtccaggc
     1741 tttcagtgac tcaaatgagg agcgagagtc gcaccctgca gacaaagagg aagtccccga
     1801 gaaggctggg aagactgagc cgagcttcac caaagagagc agcagcaaga ttcctaagaa
     1861 aggctttgtg gaggtgactg aactcacaga tgtgacgtac accagcaatt tggtacgcct
     1921 gaggcctggt cacatgaatg tggtcctgat cctgtccaat tccactaaga caagcctcct
     1981 gcagaagttt gctttggaag tctacacatt caccgggagc agcagcctcc acttctcctt
     2041 cctgacactg gacaaacacc gggagtggct ggagtatttg ctagagtttg ctcaggatgc
     2101 ggccccgatc ccaaaccagt atgacaagca ctttatggaa cgagactaca ctggctacgt
     2161 gctggccctg aacggtcaca agaagtattt ctgccttttc aagccactaa agacagtgga
     2221 tgaggagact gtggcctcct gtgaccctga ctcctcccga gggaagcctt cctgtggcct
     2281 tggccccaag cccctcaaag gcaagctgag caagttgtcc ttgtggatgg agcgcctgct
     2341 ggaaggctcc ttgcagaggt tctacatccc gtcgtggcct gagctggact gagcgaggcc
     2401 tccagaggat agcgggcccc aggaacaggg attttaagag agtctccatt gtagatttct
     2461 cttctagagc catggctaga agacctttcc tctgtcacct aggagtaaag cacgcaggtt
     2521 tgaccactag atgaacatct tccttcccct tcgggttttc tcccctggat gaatgccgca
     2581 ctacttcagt agactgccca gcccctcttc tctgctgtcc ctataacgtg ctcacacccc
     2641 tgtccttaca ctgcagaaac ccagggcttg accctgagcc gtgcctggac caacctcagg
     2701 atcttcatga gcctgtctca tggggtgggt cactcacctc tcccccagcc cctgcagcag
     2761 gctcctgctg gcccctgctt ggcctctgcc aaggtgtgtg ctctcaacac gggaagccac
     2821 cacggcttct aggtcctccg tcttcaaaag aggcctagtg tgcaagcagt tttctatgtg
     2881 gttgtgcttc tgggagcaag cagtgagaag tatattttgg gggtatcccc cacaacagtc
     2941 ggccaagcat ggttttgaga agaaaggggt gagcaggggg tgaaggtgca gcattcacat
     3001 ttagtctccc gaccgagagg gagggtgagc actggctgga ggcgcagagc cctgtgaccc
     3061 tgcgtgcact tccctgcccg tccccttccc tcaccgcact ctgtcagcac cagcacagcc
     3121 agggtgtctg ccttgccagc actggagtgg ctgagctgct gacctgtccc cagaggcctt
     3181 tttgcttctg ggttttagag tttgatacta ggagccatat cctgtgatct tgttctctga
     3241 acatagataa gctgctatag agccagtaga tttaagatgg cagcacttag tcctacccac
     3301 caagagctag gtgcaggagc ccttcctgcc tcgctctcca gtaaaacgcc aggtgtgtct
     3361 tcataccaag gaacctgacc tctctgacaa ttgcattttg aacattgttg tccccaaaga
     3421 gctgaatctt caggtcgtct cttgtgactg tgagcggaga cttgtccgga ctcctgtcag
     3481 taggcagcta gctagcatcc tccttctggc gtccctgctt cactgtttcc tccttccctt
     3541 attgctgctt cccgctgcca gatcacaccc atcagctcca gttcgcctgg ctccacgcac
     3601 cttgagctca gggccggatc atgctcgccc gctcaagggc atacccttgt ttttagagcc
     3661 aacccatgag gggagtttgg acaactgtca cacatgatgt gttctactgt caagcaagtg
     3721 cccttttgta aagggaaggg cacaaatcag ggaccggaca ttcactcagt gagtattctc
     3781 cagttgtaat tgctttgaac caagcacctc ggatcctgac tactttaaac actgagctcc
     3841 agtggtaagt gagaaattat ttgaacccag gaactctgta gttttcaaag agtctttagc
     3901 tttattaaaa agt
//
