LOCUS       NM_001359825            4329 bp    mRNA    linear   ROD 11-FEB-2025
DEFINITION  Mus musculus DnaJ heat shock protein family (Hsp40) member C14
            (Dnajc14), transcript variant 1, mRNA.
ACCESSION   NM_001359825 XM_006514249
VERSION     NM_001359825.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4329)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 4329)
  AUTHORS   Wass,C., Sauce,B., Pizzo,A. and Matzel,L.D.
  TITLE     Dopamine D1 receptor density in the mPFC responds to cognitive
            demands and receptor turnover contributes to general cognitive
            ability in mice
  JOURNAL   Sci Rep 8 (1), 4533 (2018)
   PUBMED   29540721
  REMARK    GeneRIF: The study indicates that DRiP78 levels are elevated in
            mice that express higher general cognitive ability, raising the
            possibility that a larger pool of sequestered D1 receptors is
            available for insertion into the membrane in response to cognitive
            demands.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 4329)
  AUTHORS   Sundberg,J.P., Dadras,S.S., Silva,K.A., Kennedy,V.E., Garland,G.,
            Murray,S.A., Sundberg,B.A., Schofield,P.N. and Pratt,C.H.
  TITLE     Systematic screening for skin, hair, and nail abnormalities in a
            large-scale knockout mouse program
  JOURNAL   PLoS One 12 (7), e0180682 (2017)
   PUBMED   28700664
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 4329)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24643.. PMID: 29144450]
REFERENCE   5  (bases 1 to 4329)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK045445.1, AK082579.1, AC131081.7 and BE688094.1.
            
            On Jan 18, 2018 this sequence version replaced XM_006514249.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK045445.1, AK168935.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2709              AK045445.1         4-2712
            2710-3265           AK082579.1         2620-3175
            3266-3310           AC131081.7         159226-159270
            3311-4320           AK082579.1         3222-4231
            4321-4329           BE688094.1         1-9                 c
FEATURES             Location/Qualifiers
     source          1..4329
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 77.16 cM"
     gene            1..4329
                     /gene="Dnajc14"
                     /gene_synonym="5730551F12Rik; DNAJ; DRIP78; HDJ3; LIP6"
                     /note="DnaJ heat shock protein family (Hsp40) member C14"
                     /db_xref="GeneID:74330"
                     /db_xref="MGI:MGI:1921580"
     exon            1..130
                     /gene="Dnajc14"
                     /gene_synonym="5730551F12Rik; DNAJ; DRIP78; HDJ3; LIP6"
                     /inference="alignment:Splign:2.1.0"
     exon            131..1583
                     /gene="Dnajc14"
                     /gene_synonym="5730551F12Rik; DNAJ; DRIP78; HDJ3; LIP6"
                     /inference="alignment:Splign:2.1.0"
     CDS             174..2285
                     /gene="Dnajc14"
                     /gene_synonym="5730551F12Rik; DNAJ; DRIP78; HDJ3; LIP6"
                     /note="DnaJ (Hsp40) homolog, subfamily C, member 14"
                     /codon_start=1
                     /product="dnaJ homolog subfamily C member 14"
                     /protein_id="NP_001346754.1"
                     /db_xref="CCDS:CCDS24294.1"
                     /db_xref="GeneID:74330"
                     /db_xref="MGI:MGI:1921580"
                     /translation="MAQKHPGERRLCGAHRSGGTSLSTSGSSVDPEILSFSGLRDSAE
                     TAPNGTRCLKEHSGPKYTQPPNPAHWSDPSHGPPRGPGPPRGGGYPDESETGSEESGV
                     DQELSRENETGYQEDGSPSFLSIPSACNCQGSPGVPEGTYSEEGDGSSSSLCHHCTSP
                     ALGEDEELEEEYDDEEPLKFPSDFSRVSSGKKPLSRRQKHRFLIKEDVRDSGRREPKA
                     PGRHRLARKRSQTDKRRGLGLWGVEELCQLGQAGFWWLIELLVLVGEYVETCGHLIYA
                     CRKLKGSDLDLFRVWVGVWARRLGGWARMMFQFLSQSFFCVVGLLIRILRVVGAFLLL
                     ALALFLGCLQLGWRFSVGLGNRLGWRDKTAWLFSWLGSPALHHCLTLLKDSRPWQQLV
                     RLIQWGWQELPWVKQRTKKQGNAPVASGRYCQPEEEVTRLLTMAGVPEDELNPFHVLG
                     VEATASDTELKKAYRQLAVMVHPDKNHHPRAEEAFKILRAAWDIVSNPERRKEYEMKR
                     MAENELSRSVNEFLSKLQDDLKEAMNTMMCSRCQGKHRRFEMDREPKSARYCAECNRL
                     HPAEEGDFWAESSMLGLKITYFALMDGKVYDITEWAGCQRVGISPDTHRVPYHISFGS
                     RVPGTSGRQRATPESPPADLQDFLSRIFQVPPGPMSNGNFFAAPHPGPGTTSTSRPNS
                     SVPKGEAKPKRRKKVRRPFQR"
     exon            1584..1690
                     /gene="Dnajc14"
                     /gene_synonym="5730551F12Rik; DNAJ; DRIP78; HDJ3; LIP6"
                     /inference="alignment:Splign:2.1.0"
     exon            1691..1810
                     /gene="Dnajc14"
                     /gene_synonym="5730551F12Rik; DNAJ; DRIP78; HDJ3; LIP6"
                     /inference="alignment:Splign:2.1.0"
     exon            1811..1971
                     /gene="Dnajc14"
                     /gene_synonym="5730551F12Rik; DNAJ; DRIP78; HDJ3; LIP6"
                     /inference="alignment:Splign:2.1.0"
     exon            1972..2074
                     /gene="Dnajc14"
                     /gene_synonym="5730551F12Rik; DNAJ; DRIP78; HDJ3; LIP6"
                     /inference="alignment:Splign:2.1.0"
     exon            2075..4322
                     /gene="Dnajc14"
                     /gene_synonym="5730551F12Rik; DNAJ; DRIP78; HDJ3; LIP6"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      2388
                     /gene="Dnajc14"
                     /gene_synonym="5730551F12Rik; DNAJ; DRIP78; HDJ3; LIP6"
     regulatory      3008..3013
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Dnajc14"
                     /gene_synonym="5730551F12Rik; DNAJ; DRIP78; HDJ3; LIP6"
                     /note="hexamer: AATATA"
     polyA_site      3027
                     /gene="Dnajc14"
                     /gene_synonym="5730551F12Rik; DNAJ; DRIP78; HDJ3; LIP6"
                     /note="major polyA site"
     regulatory      4099..4104
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Dnajc14"
                     /gene_synonym="5730551F12Rik; DNAJ; DRIP78; HDJ3; LIP6"
                     /note="hexamer: GATAAA"
     polyA_site      4136
                     /gene="Dnajc14"
                     /gene_synonym="5730551F12Rik; DNAJ; DRIP78; HDJ3; LIP6"
     polyA_site      4322
                     /gene="Dnajc14"
                     /gene_synonym="5730551F12Rik; DNAJ; DRIP78; HDJ3; LIP6"
ORIGIN      
        1 ggacggaagg cggaagcgga gcgtgagcgg gaggcggagc cgggggagct gctcctgtag
       61 ctccccctgg cagctccccc tggcctcagg cgcagctgct tgaggaggga ggagttaccg
      121 ctgctgctcg gcaatgatgg cagtgaccta aaatcctcag gaagcccggg gtcatggccc
      181 agaagcaccc gggagaaaga aggttgtgtg gagcccaccg cagtggtggt acctccctca
      241 gtacatcagg atcctctgtg gaccccgaaa tactttcatt ctcaggactc agggactcag
      301 cagagactgc tcctaatggt acacgatgcc tcaaagagca ctccggccct aagtacacac
      361 agcctccaaa tccagcccac tggtcagatc caagccatgg tcctccaagg ggtccaggac
      421 cacctagagg aggaggctac cctgatgaga gcgagacagg ttcagaagag tcaggagtgg
      481 accaggaact ctcaagagag aatgagactg ggtaccagga ggatgggagt ccttcttttc
      541 tttccattcc atctgcttgt aactgccagg gaagccctgg agtccccgaa ggaacttact
      601 ccgaggaagg agatggctct tctagcagcc tttgccacca ttgcacctct ccagccttgg
      661 gggaagatga agagttggaa gaagaatatg atgatgagga acctcttaaa tttcccagtg
      721 atttttcacg tgtgtccagt ggaaagaaac ccttgtcccg gaggcagaag caccgttttc
      781 tgatcaagga ggatgttcgg gatagtggac gcagagaacc caaggcccca ggtcgtcatc
      841 ggctggcccg aaaaagaagt cagacagata agcgcagagg cctgggactg tggggagtag
      901 aggaactatg tcagcttgga caagcaggct tctggtggct gattgaactt ctggtattgg
      961 tgggagagta tgtggaaacc tgtggccatc tcatttacgc atgcaggaag ctgaaaggca
     1021 gtgacctgga cctttttcga gtctgggtgg gggtctgggc caggagactg gggggctggg
     1081 cccgcatgat gttccagttt ctaagccaga gcttcttctg tgtggtgggg ctgctcatcc
     1141 gtattcttag ggtagtgggt gctttcctac tcctggctct cgccctcttt ttgggatgtc
     1201 tacaattggg ctggaggttt tcggtgggac tgggcaaccg gttaggctgg agggataaga
     1261 ccgcttggct gttctcttgg ctgggttctc cagccttgca tcattgcttg actctgctga
     1321 aagatagcag gccatggcag cagctggtaa ggttaataca gtggggctgg caggagctgc
     1381 cctgggtcaa acagaggact aagaaacagg gcaatgcacc tgtagctagc gggcgatact
     1441 gccagcctga agaggaagtg acccgactct tgaccatggc tggggttcct gaagatgaac
     1501 taaacccttt tcatgtgctg ggggttgaag ctacagcatc cgacactgaa ctaaagaagg
     1561 cctataggca gctagcagta atggtccatc ctgataaaaa tcaccatccc cgggctgagg
     1621 aggccttcaa aattttgcgg gcagcttggg acattgtcag caacccagag aggcggaagg
     1681 aatatgagat gaaacggatg gcagagaatg agctcagccg gtcagtgaat gagtttctgt
     1741 cgaaactaca agatgacctc aaggaggcaa tgaacacgat gatgtgcagc agatgccaag
     1801 gaaagcatag gaggtttgaa atggaccggg aacccaagag tgccagatac tgtgctgagt
     1861 gtaacaggct gcatcctgct gaggaaggag acttttgggc agagtcgagc atgctgggcc
     1921 tcaagatcac ttactttgcg ctgatggatg gaaaggtgta tgacatcaca gagtgggctg
     1981 gatgccagcg tgtgggtatc tccccagata ctcacagagt tccttaccac atctcatttg
     2041 gttctcgggt acccggcacc agtggccggc agagggccac tccagagtcc cctcctgctg
     2101 acctgcagga tttcttgagc cggatctttc aagtacctcc ggggccgatg tccaatggga
     2161 acttctttgc cgcacctcac cctggccctg ggaccacttc gacctctagg cccaacagtt
     2221 cagtacccaa gggagaagcc aaacctaaac ggcggaagaa agtgaggcgg ccctttcaac
     2281 gatgacaccc cttctcttcc ttcctcaaat caatgtcagg gagtcaaaag ggctgtgtac
     2341 agcacaggat ggaatttgat ttattttaaa atactttaaa aagggaaaca ttttaaattg
     2401 ttcactcagt acttagagga agcccatgac ctcttctccc tcttccccaa cacccaggaa
     2461 ctgaatcttg ttttctgaca ataccaaaga aataggaggt ggtcagagca aagaacttag
     2521 gggctggacc tagtccagac agtatgcttc tgaggtgtgg gaactgggga tttctctggg
     2581 gtctgtatgc ctttatctta tcatctgctc ttaagagcag atgaaacaca ccccctttta
     2641 aatgagtgta tcttatttct taaacccata tcaggggttc ccctcccccc tttaccctga
     2701 tatactagct aaaagaaaaa gcatgtagcc ctaattttgg agacacagaa ctcaagagtg
     2761 gaaactgatt tttttcctct gactttcact ttattggtaa gacacctaac ttcaggcttg
     2821 ttgttgcaag gatggccaaa attaattaat ttttaaaaag cagatttatg ccctgtgccc
     2881 ttgggtgagg gggaaggata gaggggttcc cagaggcccc cttgttagcc aagggtttgt
     2941 atttttttaa gtttgttcat atttgtatgt acatatctat ttaaagccag gagattatct
     3001 ttctataaat atataactgg caacttacat cttccttctc ttctttaccc atgtagctgg
     3061 gagtcctttt ctattttctt ttggagataa gagtcttact gtgtagacca ggctggactc
     3121 cagattgcag tgattctcct gcctctgcct ccacttcctg agggctagct agtattatag
     3181 gcatgtgcct ccactactca cttgtgagct cttttttctt atttgagaat tctttccttg
     3241 ctgttagctg tgagtgaaag gtattggacc aaaggagtag agacaaaatt ttgcttaaaa
     3301 gtttttttta tagtaagtca gcattttgca ttttctcccc agcattatga gaaaatctct
     3361 ctgtccttgc ttatcaaatt tcagccataa ctgaaagact ttattttaag aaaaatatac
     3421 agcaaaacag aacttgaagt tggtaggttt agaagatatg gaaaaacata atcaccagaa
     3481 aagctgccca aacaatgatg gcttcttgct agatagagga gagtgagtgg tagtgccctt
     3541 aacctcatcc acctttcctg attcagagaa tcttgaccct atgaagactg gacccaggaa
     3601 ccccattttc cagtttcttc cttcttggag tttagatagg tttatcttat ctctcaggct
     3661 tccaagatac agaagatagt gtggagaagg gaaaacatta tatattagtt ccagtgcctt
     3721 ccctcaatgc ctgcagaact agcaaaccat cttttagtat ttgttgattc caaagagacg
     3781 aaccccatgg aactggggta gcttaggcag cagcacgctg agcagcgagg cagtgttgat
     3841 gaggaagtga gcagcatcgt acttggtgta gaagctggcc aggaggtaac taggagaaaa
     3901 gaattaggat gatggaggtt ggcctcccaa atcacattca tgccttacca gtgacttttc
     3961 tattttgaac tactagtttt attgcatgta gtccaacaac tatttcagct aatcaatggt
     4021 atttaatgag gttcaggata taatcagaag gcatctttaa ctagagatga taaatcagtt
     4081 tgtttgttaa tggttaatga taaactgcaa atgacagcca aagctgtttc agcatatatg
     4141 acttttggag ccctttttgc ttcctttctc caagtcagtt ttacttttta accattaata
     4201 tacattctgc ctttaccttc ttgctttctt ttgggactgt aaaatcactt ggctttagtt
     4261 aggagtttgg tttattttca gtcccttctc cctttcctta ataccatgga accagcaagg
     4321 aaaaaaaaa
//
