LOCUS       NM_008299               1017 bp    mRNA    linear   ROD 07-FEB-2025
DEFINITION  Mus musculus DnaJ heat shock protein family (Hsp40) member B3
            (Dnajb3), mRNA.
ACCESSION   NM_008299
VERSION     NM_008299.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1017)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1017)
  AUTHORS   Roy,T.A., Bubier,J.A., Dickson,P.E., Wilcox,T.D., Ndukum,J.,
            Clark,J.W., Sukoff Rizzo,S.J., Crabbe,J.C., Denegre,J.M.,
            Svenson,K.L., Braun,R.E., Kumar,V., Murray,S.A., White,J.K.,
            Philip,V.M. and Chesler,E.J.
  TITLE     Discovery and validation of genes driving drug-intake and related
            behavioral traits in mice
  JOURNAL   Genes Brain Behav 23 (1), e12875 (2024)
   PUBMED   38164795
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   3  (bases 1 to 1017)
  AUTHORS   Nejat,S., Menikdiwela,K.R., Efotte,A., Scoggin,S., Vandanmagsar,B.,
            Thornalley,P.J., Dehbi,M. and Moustaid-Moussa,N.
  TITLE     Genetic Deletion of DNAJB3 Using CRISPR-Cas9, Produced Discordant
            Phenotypes
  JOURNAL   Genes (Basel) 14 (10), 1857 (2023)
   PUBMED   37895206
  REMARK    GeneRIF: Genetic Deletion of DNAJB3 Using CRISPR-Cas9, Produced
            Discordant Phenotypes.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1017)
  AUTHORS   Sundberg,J.P., Dadras,S.S., Silva,K.A., Kennedy,V.E., Garland,G.,
            Murray,S.A., Sundberg,B.A., Schofield,P.N. and Pratt,C.H.
  TITLE     Systematic screening for skin, hair, and nail abnormalities in a
            large-scale knockout mouse program
  JOURNAL   PLoS One 12 (7), e0180682 (2017)
   PUBMED   28700664
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1017)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24643.. PMID: 29144450]
REFERENCE   6  (bases 1 to 1017)
  AUTHORS   Berruti,G. and Martegani,E.
  TITLE     The deubiquitinating enzyme mUBPy interacts with the sperm-specific
            molecular chaperone MSJ-1: the relation with the proteasome,
            acrosome, and centrosome in mouse male germ cells
  JOURNAL   Biol Reprod 72 (1), 14-21 (2005)
   PUBMED   15342353
REFERENCE   7  (bases 1 to 1017)
  AUTHORS   Yu,S.S. and Takenaka,O.
  TITLE     Molecular cloning, structure, and testis-specific expression of
            MFSJ1, a member of the DNAJ protein family, in the Japanese monkey
            (Macaca fuscata)
  JOURNAL   Biochem Biophys Res Commun 301 (2), 443-449 (2003)
   PUBMED   12565881
REFERENCE   8  (bases 1 to 1017)
  AUTHORS   Berruti,G. and Martegani,E.
  TITLE     mUBPy and MSJ-1, a deubiquitinating enzyme and a molecular
            chaperone specifically expressed in testis, associate with the
            acrosome and centrosome in mouse germ cells
  JOURNAL   Ann N Y Acad Sci 973, 5-7 (2002)
   PUBMED   12485825
  REMARK    GeneRIF: a molecular chaperone, specifically expressed in testis,
            associates with the acrosome and centrosome in mouse germ cells
REFERENCE   9  (bases 1 to 1017)
  AUTHORS   Berruti,G. and Martegani,E.
  TITLE     MSJ-1, a mouse testis-specific DnaJ protein, is highly expressed in
            haploid male germ cells and interacts with the testis-specific heat
            shock protein Hsp70-2
  JOURNAL   Biol Reprod 65 (2), 488-495 (2001)
   PUBMED   11466217
REFERENCE   10 (bases 1 to 1017)
  AUTHORS   Berruti,G., Perego,L., Borgonovo,B. and Martegani,E.
  TITLE     MSJ-1, a new member of the DNAJ family of proteins, is a male germ
            cell-specific gene product
  JOURNAL   Exp Cell Res 239 (2), 430-441 (1998)
   PUBMED   9521861
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            U95607.1 and AK005690.1.
            
            On Apr 11, 2009 this sequence version replaced NM_008299.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript is intronless :: U95607.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-767               U95607.1           3-769
            768-1017            AK005690.1         717-966
FEATURES             Location/Qualifiers
     source          1..1017
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 44.55 cM"
     gene            1..1017
                     /gene="Dnajb3"
                     /gene_synonym="Hsj3; MSJ-1; Msj1"
                     /note="DnaJ heat shock protein family (Hsp40) member B3"
                     /db_xref="GeneID:15504"
                     /db_xref="MGI:MGI:1306822"
     exon            1..1017
                     /gene="Dnajb3"
                     /gene_synonym="Hsj3; MSJ-1; Msj1"
                     /inference="alignment:Splign:2.1.0"
     CDS             71..799
                     /gene="Dnajb3"
                     /gene_synonym="Hsj3; MSJ-1; Msj1"
                     /note="HSJ-3; heat shock protein J3; dnaJ protein homolog
                     3; heat shock protein, DNAJ-like 3; DnaJ (Hsp40) homolog,
                     subfamily B, member 3"
                     /codon_start=1
                     /product="dnaJ homolog subfamily B member 3"
                     /protein_id="NP_032325.2"
                     /db_xref="CCDS:CCDS15142.1"
                     /db_xref="GeneID:15504"
                     /db_xref="MGI:MGI:1306822"
                     /translation="MVDYYEVLGVPRQASAEAIRKAYRKLALKWHPDKNPEHKEEAER
                     RFKQVAQAYEVLSDVRKREVYDRCGEVGEVGGGGAAGSPFHDAFQYVFSFRDPAEVFR
                     EFFGGHDPFSFDFFGGDPLENFFGDRRSTRGSRSRGAVPFSTSFTEFPGFGGGFASLD
                     TGFTSFGSPGNSGLSSFSMSCGGGAAGNYKSVSTSTEIINGKKITTKRIVENGQERVE
                     VEEDGELKSLIINGKEQLLRINTQ"
ORIGIN      
        1 ggccggtagg cgggcgttca gcagctgcca ccgccgctcc agcgccgagg ccgcgggccg
       61 gccagccgcc atggtggact actacgaggt gctgggcgtg ccgcggcagg cctcagccga
      121 ggccatccgc aaggcgtacc gcaagcttgc gctcaagtgg cacccggaca agaaccccga
      181 gcacaaggag gaggccgaga ggcggttcaa gcaggtggcg caggcctacg aggtcttatc
      241 ggacgtccgc aagcgcgagg tgtacgaccg ctgcggcgaa gtgggcgagg tgggcggagg
      301 cggcgcggcg ggcagcccgt tccacgatgc cttccagtac gtcttctcct tccgagaccc
      361 cgcggaggtc ttcagggagt tcttcggggg ccacgaccct ttctccttcg acttcttcgg
      421 gggagacccc cttgagaact tttttgggga tcggaggagc acccgtggaa gcagaagccg
      481 aggggctgta cccttctcta cctcctttac cgaattccca ggatttgggg gtggcttcgc
      541 ttcgttagat actggattca catccttcgg ttctccagga aactcgggcc tttcttcttt
      601 ctccatgtct tgcggcggtg gggcggcagg caactacaag tcggtgtcaa cctccaccga
      661 aataattaat ggcaaaaaaa tcaccaccaa gagaatcgtt gagaatggtc aagaaagggt
      721 ggaagtggaa gaagatggag agttaaagtc cctgataatt aatggcaaag agcagctgct
      781 tcgcatcaat actcagtaaa gactaaagtg tcttttaagg actatcagga cttttttgtt
      841 taaacgcgtt ttcaagggaa ctctactttc agaacaactg tattccagac attatatgca
      901 gctcatgtcg gtgcctcttg ttattgttgg gatcgcaggg ataggatctc tcttggtctt
      961 tatgcctgtt gtaaatatct gtatgccttt ggcacttatt aaacttaatc ctgaggc
//
