LOCUS       NM_001033155            1851 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus DnaJ heat shock protein family (Hsp40) member B14
            (Dnajb14), mRNA.
ACCESSION   NM_001033155 XM_001473173 XM_924518
VERSION     NM_001033155.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1851)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1851)
  AUTHORS   Sopha,P., Kadokura,H., Yamamoto,Y.H., Takeuchi,M., Saito,M.,
            Tsuru,A. and Kohno,K.
  TITLE     A novel mammalian ER-located J-protein, DNAJB14, can accelerate
            ERAD of misfolded membrane proteins
  JOURNAL   Cell Struct Funct 37 (2), 177-187 (2012)
   PUBMED   23018488
  REMARK    GeneRIF: Compared with DNAJB12 mRNA that was widely expressed in
            mouse tissues, DNAJB14 mRNA was expressed more weakly, being most
            abundant in testis, implying its specific role in this tissue.
REFERENCE   3  (bases 1 to 1851)
  AUTHORS   McClintock,T.S., Glasser,C.E., Bose,S.C. and Bergman,D.A.
  TITLE     Tissue expression patterns identify mouse cilia genes
  JOURNAL   Physiol Genomics 32 (2), 198-206 (2008)
   PUBMED   17971504
  REMARK    GeneRIF: Dnajb14 is most abundantly expressed in tissues rich in
            highly ciliated cells, such as olfactory sensory neurons, and is
            predicted to be important to cilia.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC125154.3 and AC146607.2.
            
            On or before Apr 5, 2009 this sequence version replaced
            XM_924518.2, XM_001473173.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC117718.1, AK017735.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-382               AC125154.3         183011-183392
            383-554             AC146607.2         130983-131154       c
            555-700             AC146607.2         123474-123619       c
            701-886             AC146607.2         114055-114240       c
            887-981             AC146607.2         112450-112544       c
            982-1091            AC146607.2         111573-111682       c
            1092-1264           AC146607.2         110370-110542       c
            1265-1851           AC146607.2         107496-108082       c
FEATURES             Location/Qualifiers
     source          1..1851
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 63.94 cM"
     gene            1..1851
                     /gene="Dnajb14"
                     /gene_synonym="5730496F10Rik"
                     /note="DnaJ heat shock protein family (Hsp40) member B14"
                     /db_xref="GeneID:70604"
                     /db_xref="MGI:MGI:1917854"
     exon            1..382
                     /gene="Dnajb14"
                     /gene_synonym="5730496F10Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             250..1389
                     /gene="Dnajb14"
                     /gene_synonym="5730496F10Rik"
                     /note="DnaJ (Hsp40) homolog, subfamily B, member 14"
                     /codon_start=1
                     /product="dnaJ homolog subfamily B member 14"
                     /protein_id="NP_001028327.1"
                     /db_xref="CCDS:CCDS51077.1"
                     /db_xref="GeneID:70604"
                     /db_xref="MGI:MGI:1917854"
                     /translation="MEGNRDEAEKCVQIAREALSAGNRDKAQRFLQKAEKLYPLPAAR
                     ALLEIIMKNGSTAGSSTHCRKPPGSSDQSKPSCGKDGTSGAGEGGKVYTKDQVEGVLS
                     INKCKNYYEVLGVTKDAGDEDLKKAYRKLALKFHPDKNHAPGATDAFKKIGNAYAVLS
                     NPEKRKQYDLTGSEEQACNHQNNGRFNFHRGCEADITPEDLFNIFFGGGFPSGSVHSF
                     SNGRAAYSHQHQHRHSGHEREEERADGGFSVFIQLMPIIVLILVSLLSQLMVSNPPYS
                     LYPRSGSGQTIKMQTENLGVVYYVSKDFKSEYKGTLLQKVEKSVEEDYVTNIRNNCWK
                     ERQQKTDMQYAAKVYRDEQLRRKADALSMENCKELERLTSLYKGG"
     exon            383..554
                     /gene="Dnajb14"
                     /gene_synonym="5730496F10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            555..700
                     /gene="Dnajb14"
                     /gene_synonym="5730496F10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            701..886
                     /gene="Dnajb14"
                     /gene_synonym="5730496F10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            887..981
                     /gene="Dnajb14"
                     /gene_synonym="5730496F10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            982..1091
                     /gene="Dnajb14"
                     /gene_synonym="5730496F10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1092..1264
                     /gene="Dnajb14"
                     /gene_synonym="5730496F10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1265..1851
                     /gene="Dnajb14"
                     /gene_synonym="5730496F10Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1469..1474
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Dnajb14"
                     /gene_synonym="5730496F10Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      1502
                     /gene="Dnajb14"
                     /gene_synonym="5730496F10Rik"
                     /note="major polyA site"
     polyA_site      1558
                     /gene="Dnajb14"
                     /gene_synonym="5730496F10Rik"
ORIGIN      
        1 gggttaccgc gtcggcttta cggtccgcca ggcccgggag ggacgcggct ggcgccgctg
       61 cggccgcggg gggcggggag gcggccgtga ggaggcggag ctgcgaggcc gcccgtcgcc
      121 gggccgccgc cgcggtgccc gctcctcccc gcgccgtgcc gcgccgtgcc ccgcccggcc
      181 gcctcgcctc ctccgcggcg ggcccccctc gcagctgcgc ggccgcggac accgaggcag
      241 gcgcgagcca tggagggcaa ccgcgacgag gcggagaaat gcgtgcagat cgctcgcgag
      301 gccctgagcg ccggcaaccg cgacaaggcc cagcgcttcc tccagaaggc cgagaagctg
      361 tacccgctgc cggccgcgcg cgcgttattg gaaataatta tgaaaaacgg cagcaccgct
      421 ggaagtagca cgcattgccg aaaacctcct gggagcagcg accagagcaa gcccagctgt
      481 ggaaaggacg gcacttctgg tgctggggaa ggcgggaaag tctataccaa agaccaagta
      541 gagggcgtgc tcagcataaa caaatgtaaa aattactacg aagtcctcgg agttacaaaa
      601 gatgctggtg atgaagattt gaaaaaagct tataggaagc ttgctttgaa gtttcatcca
      661 gacaaaaacc acgcccctgg agccacggat gctttcaaaa agattggaaa cgcttacgcc
      721 gtcctaagca atccagagaa acgaaaacag tatgacctca caggcagtga agagcaagcc
      781 tgtaaccacc agaacaacgg caggttcaat ttccaccggg gctgtgaggc cgacataact
      841 cccgaagacc tgttcaatat cttctttggc ggtggatttc cttcaggtag tgtacattca
      901 ttttcaaatg gccgggctgc ttacagccat caacatcagc accgacacag tgggcatgaa
      961 agagaagaag aaagagcgga tggaggcttc tctgtcttca ttcagctcat gcccatcatt
     1021 gtgctgatcc ttgtgtcctt gttaagccag ctgatggtct cgaaccctcc gtactcctta
     1081 taccccagat ctggatcagg acaaactatt aaaatgcaga cagaaaactt gggtgttgtt
     1141 tattacgtca gtaaggactt taaaagcgaa tataaaggaa cactattaca aaaagtagaa
     1201 aagagtgtgg aagaggatta cgtgactaat attcgaaata actgctggaa agaaagacag
     1261 cagaaaacag atatgcagta tgcagccaaa gtgtaccgtg atgagcagct gcggaggaag
     1321 gcggatgccc tgagcatgga gaactgcaag gagctagagc ggctgaccag tctctacaag
     1381 gggggataag ctgggtccca cctgctcctt tctgtgtact ctgtcttctc tgtaaatttc
     1441 atgtcgccat gaagctgaag aagatttgat taaagactaa gctgagtagt tgattcctga
     1501 aatcttggac tgttaatgac ctactggctc atttcaatag taagaactga aaactaaata
     1561 ttttagtatg cttctgcaat tactttaact ttaaaatctt atatgattcc ttacaaagtc
     1621 tggagaggat tatcacaccg gtagcagttg ccagctttgt gattctccat tgttcctttg
     1681 ccatgtaaat atttctagga tgattttgta cacatgcgag cgcttgcctt ttatttaaat
     1741 tattttagtg tttagctcca tgagacacta ggttcgggcc gatggaatgg acacagtcac
     1801 atttcccatt aggtgtttgc gtgtgtggag tttaaacaat gaacattttt c
//
