LOCUS       NM_019965               3062 bp    mRNA    linear   ROD 12-FEB-2025
DEFINITION  Mus musculus DnaJ heat shock protein family (Hsp40) member B12
            (Dnajb12), transcript variant 2, mRNA.
ACCESSION   NM_019965
VERSION     NM_019965.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3062)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3062)
  AUTHORS   Sundberg,J.P., Dadras,S.S., Silva,K.A., Kennedy,V.E., Garland,G.,
            Murray,S.A., Sundberg,B.A., Schofield,P.N. and Pratt,C.H.
  TITLE     Systematic screening for skin, hair, and nail abnormalities in a
            large-scale knockout mouse program
  JOURNAL   PLoS One 12 (7), e0180682 (2017)
   PUBMED   28700664
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3062)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24643.. PMID: 29144450]
REFERENCE   4  (bases 1 to 3062)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   5  (bases 1 to 3062)
  AUTHORS   Ohtsuka,K. and Hata,M.
  TITLE     Mammalian HSP40/DNAJ homologs: cloning of novel cDNAs and a
            proposal for their classification and nomenclature
  JOURNAL   Cell Stress Chaperones 5 (2), 98-112 (2000)
   PUBMED   11147971
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC155939.6 and AC154040.7.
            
            On Dec 5, 2019 this sequence version replaced NM_019965.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK089427.1, SRR7652917.812135.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-228               AC155939.6         144341-144568
            229-409             AC155939.6         154786-154966
            410-555             AC155939.6         155598-155743
            556-741             AC155939.6         157430-157615
            742-821             AC155939.6         157696-157775
            822-931             AC154040.7         196773-196882       c
            932-1104            AC154040.7         195353-195525       c
            1105-1256           AC154040.7         194612-194763       c
            1257-3062           AC154040.7         191817-193622       c
FEATURES             Location/Qualifiers
     source          1..3062
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 29.64 cM"
     gene            1..3062
                     /gene="Dnajb12"
                     /gene_synonym="Dj10; mDj10"
                     /note="DnaJ heat shock protein family (Hsp40) member B12"
                     /db_xref="GeneID:56709"
                     /db_xref="MGI:MGI:1931881"
     exon            1..228
                     /gene="Dnajb12"
                     /gene_synonym="Dj10; mDj10"
                     /inference="alignment:Splign:2.1.0"
     CDS             96..1226
                     /gene="Dnajb12"
                     /gene_synonym="Dj10; mDj10"
                     /note="isoform 2 is encoded by transcript variant 2; DnaJ
                     homolog 10; dnaJ homolog subfamily B member 12; DnaJ
                     (Hsp40) homolog, subfamily B, member 12"
                     /codon_start=1
                     /product="dnaJ homolog subfamily B member 12 isoform 2"
                     /protein_id="NP_064349.2"
                     /db_xref="CCDS:CCDS23867.1"
                     /db_xref="GeneID:56709"
                     /db_xref="MGI:MGI:1931881"
                     /translation="MESNKDEAERCISIALKAIQSNQPERALRFLEKAQRLYPTPRVS
                     ALIESLNQKPQSTGDHPQPTDTTHTTTKKAGGTETPSANGEAGGGESAKGYTSEQVAA
                     VKRVKQCKDYYEILGVSRSASDEDLKKAYRKLALKFHPDKNHAPGATEAFKAIGTAYA
                     VLSNPEKRKQYDQFGDDKSQAARHGHSHGDFHRGFEADISPEDLFNMFFGGGFPSSNV
                     HVYSNGRMRYTYQQRQDRRDNQGDGGLGVFVQLMPILILILVSALSQLMVSSPPYSLS
                     PRPSVGHIHKRVTDHLNVAYYVADTFSEEYTGSSLKTVERNVEDDYIANLRNNCWKEK
                     QQKEGLLYRARYFGDTDMYHRAQKMGTPSCNRLSEVQASLHG"
     exon            229..409
                     /gene="Dnajb12"
                     /gene_synonym="Dj10; mDj10"
                     /inference="alignment:Splign:2.1.0"
     exon            410..555
                     /gene="Dnajb12"
                     /gene_synonym="Dj10; mDj10"
                     /inference="alignment:Splign:2.1.0"
     exon            556..741
                     /gene="Dnajb12"
                     /gene_synonym="Dj10; mDj10"
                     /inference="alignment:Splign:2.1.0"
     exon            742..821
                     /gene="Dnajb12"
                     /gene_synonym="Dj10; mDj10"
                     /inference="alignment:Splign:2.1.0"
     exon            822..931
                     /gene="Dnajb12"
                     /gene_synonym="Dj10; mDj10"
                     /inference="alignment:Splign:2.1.0"
     exon            932..1104
                     /gene="Dnajb12"
                     /gene_synonym="Dj10; mDj10"
                     /inference="alignment:Splign:2.1.0"
     exon            1105..1256
                     /gene="Dnajb12"
                     /gene_synonym="Dj10; mDj10"
                     /inference="alignment:Splign:2.1.0"
     exon            1257..3062
                     /gene="Dnajb12"
                     /gene_synonym="Dj10; mDj10"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3043..3048
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Dnajb12"
                     /gene_synonym="Dj10; mDj10"
                     /note="hexamer: AATATA"
     polyA_site      3062
                     /gene="Dnajb12"
                     /gene_synonym="Dj10; mDj10"
                     /note="major polyA site"
ORIGIN      
        1 cttccgcgcc ggcctgcccc gcgacgcgcc ggcggctggc gcagcccttc gctcgcccgg
       61 cctccccctc cctggttccg tgctcgggtt ccgccatgga atccaacaag gatgaagccg
      121 agcgctgtat cagcatcgcc ctcaaggcca tccaaagcaa ccagcccgag cgggcgctgc
      181 gcttcctgga gaaggcgcag cggctctacc cgacgccacg agtcagcgca ctgatcgagt
      241 ccctcaacca aaaaccacag tccaccggtg atcaccctca acccacagac actacccata
      301 ccaccaccaa gaaggcaggc gggaccgaaa ccccctcagc caacggcgag gcaggaggag
      361 gggagagcgc caagggctat acctcagagc aggtggcagc tgtgaaaagg gtcaagcagt
      421 gtaaagatta ctatgagatc cttggggtaa gcagaagtgc ctcagatgag gacctaaaga
      481 aggcctaccg caagctggcc ctcaagttcc atccagacaa gaaccatgcg cctggggcca
      541 ctgaagcttt caaagccatt ggcacagcgt atgccgtact cagcaaccca gagaaaagga
      601 aacagtacga ccagtttggt gatgacaaga gccaggctgc ccggcacggc cacagccacg
      661 gggacttcca ccgaggcttt gaggctgaca tctccccaga agacctcttt aacatgttct
      721 ttggtggcgg ctttccttcc agtaacgttc atgtctacag caatggccga atgcggtaca
      781 cctaccagca gaggcaagac cgcagagaca accagggtga tggcgggcta ggagtgttcg
      841 tgcagctgat gcccatcctc atcctcatcc tcgtgtctgc gctcagccag ctcatggtgt
      901 ccagtcctcc ctacagcctg agcccgagac cgtcagtggg ccacatccac aagcgagtca
      961 ctgaccacct gaacgtcgcc tactacgtgg cagacacctt ctccgaagag tacacgggct
     1021 ccagcctcaa aacagtggaa cggaatgtag aggatgacta catcgccaac ctgcgcaaca
     1081 actgctggaa ggagaagcag cagaaggaag gcttgctgta ccgagcccgc tactttggtg
     1141 acacagacat gtaccacaga gcacagaaga tgggcacccc gagttgcaat cggctgtcag
     1201 aggtgcaggc ctccctgcat ggatagttct gggccagcca caccacccag gtccaaacta
     1261 tgaaatccct ggagaatttt tggtgacaca cactgagcca gccacagtga tggactgtat
     1321 atttaaggaa agacatacac agaaaaaatt taaatggaac tggaagccaa acaccgcaca
     1381 gccatcctct ctcagacagt gaatgcagaa agctcttagg acagacagac agacagccta
     1441 cctcgggctg cttcctcctc tcccagggca ggcaagaagc tccgcatcac tggctcctag
     1501 gataccgaaa ccatggcaac gaaagtagaa tgtaaaactt gcagcaaatg tctgtgggga
     1561 aggactgggg gaggggacac cccactgtgt ctcctccctc ctccctgagc tgccaccagt
     1621 cactcaagga gaaatcaggc tgaggcatgg gccaaggaac agagaggaga gaattccaga
     1681 gaacgtaact tagaaatgcg tatgtatgta tatatatatc tatttatatg taaatagaca
     1741 tatataaaga tatatatata tatataaagt cttttaaaac tattcaggga ttcaattaag
     1801 atgttcagct gacttgctcc ataatttaga aaacggggcc tgtttgggaa ggcagcctgg
     1861 ttttcacaag ctagacagta gccgtagccg acagcatacg gaaagtcaaa tcagatatta
     1921 gtgtcgccct tagccccagc ctgactgatg gcagcagtaa tcatggtggt ataaatccat
     1981 agaaaacttg caaaggtctc caggcttatg gttaaggtag gggaagagcc tggggcaggg
     2041 aatggtgccc ctggagatag ctgctcagta ttgggctaca gcagagatcc cagacaaagc
     2101 cctctgggat ggggccagct cctcaagctg cctcctctct ggccagcctc aggtgggctc
     2161 gccgccctca tgcccgggag ccctgcagcc actcccctgc ccatacctct tccccaccca
     2221 agtccccagg tgggtttgcc ttacaggtgc cacagggcac agctccacca ttgccaacag
     2281 gttttctaag ttgcgcacca aggactccag aaggctgctc ctcccagagc tgagccaggc
     2341 cctgagtgca gcccagcttg tggagagcca gtgctgtgag cgcctgtctt cactccacag
     2401 tgggcccacc gggctccact cattggatga agaatccact acgaccagaa tggcttcccc
     2461 ttcagatgag gctctttatc aaaacagcca ttgctgccag gggaaggagg aggttcaact
     2521 cctcctgcgt ttattacggg cctttgggaa ttgccgtttc ccccagtttt cctctggcca
     2581 cgggtgtgcc gatcacctac agacttccaa agccttactt ccccaagctg ccagcccaga
     2641 ggtggtaact gacaccacca ccaccactcc ccacccccac ccccccaccc ccaccaaggg
     2701 tgtctctctc atacaacccc ctaacgaatg ggatgcttgc tgggaaagga agcttggtta
     2761 ggaattgtca aattggtctt ttttttcttt tttttttttt ttaaacaagg tcccaccctg
     2821 caatgaagtg gccaccctgg cctagagaga taataataac tgggtgtggg ccagagtacc
     2881 ccacccgtag tggcctggtg ctctgcccct gccaccccac ctgtccagtc ttggtagctg
     2941 tccctggagg ggctgagcca tgtgcaataa gaacacagat cctaaaggat cccctgagaa
     3001 gctgtatttc ttgaattaga attctgatac tgtacatgta taaatatatg tttattatgt
     3061 ga
//
