LOCUS       NM_001033548            2254 bp    mRNA    linear   ROD 16-OCT-2024
DEFINITION  Mus musculus dynein, axonemal assembly factor 3 (Dnaaf3), mRNA.
ACCESSION   NM_001033548 XM_488102 XM_911611
VERSION     NM_001033548.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2254)
  AUTHORS   Chen,D., Fan,G., Xu,Y., Luo,P., Chen,Q., Chen,X., Guo,Z., Zhu,X.
            and Gao,Y.
  TITLE     A novel homozygous mutation in the DNAAF3 gene leads to severe
            asthenozoospermia and teratospermia
  JOURNAL   J Cell Mol Med 28 (18), e70092 (2024)
   PUBMED   39289782
REFERENCE   2  (bases 1 to 2254)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 2254)
  AUTHORS   Cheong,A., Degani,R., Tremblay,K.D. and Mager,J.
  TITLE     A null allele of Dnaaf2 displays embryonic lethality and mimics
            human ciliary dyskinesia
  JOURNAL   Hum Mol Genet 28 (16), 2775-2784 (2019)
   PUBMED   31107948
REFERENCE   4  (bases 1 to 2254)
  AUTHORS   Dong,F., Shinohara,K., Botilde,Y., Nabeshima,R., Asai,Y.,
            Fukumoto,A., Hasegawa,T., Matsuo,M., Takeda,H., Shiratori,H.,
            Nakamura,T. and Hamada,H.
  TITLE     Pih1d3 is required for cytoplasmic preassembly of axonemal dynein
            in mouse sperm
  JOURNAL   J Cell Biol 204 (2), 203-213 (2014)
   PUBMED   24421334
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC161218.10, AK134335.1 and AI429530.1.
            
            On Jun 9, 2018 this sequence version replaced NM_001033548.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK134335.1, BC150983.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164142 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-23                AC161218.10        147799-147821       c
            24-2212             AK134335.1         2-2190
            2213-2254           AI429530.1         1-42                c
FEATURES             Location/Qualifiers
     source          1..2254
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 2.61 cM"
     gene            1..2254
                     /gene="Dnaaf3"
                     /gene_synonym="6030429G01Rik; b2b1739Clo"
                     /note="dynein, axonemal assembly factor 3"
                     /db_xref="GeneID:436022"
                     /db_xref="MGI:MGI:3588207"
     exon            1..88
                     /gene="Dnaaf3"
                     /gene_synonym="6030429G01Rik; b2b1739Clo"
                     /inference="alignment:Splign:2.1.0"
     exon            89..177
                     /gene="Dnaaf3"
                     /gene_synonym="6030429G01Rik; b2b1739Clo"
                     /inference="alignment:Splign:2.1.0"
     exon            178..320
                     /gene="Dnaaf3"
                     /gene_synonym="6030429G01Rik; b2b1739Clo"
                     /inference="alignment:Splign:2.1.0"
     exon            321..414
                     /gene="Dnaaf3"
                     /gene_synonym="6030429G01Rik; b2b1739Clo"
                     /inference="alignment:Splign:2.1.0"
     exon            415..572
                     /gene="Dnaaf3"
                     /gene_synonym="6030429G01Rik; b2b1739Clo"
                     /inference="alignment:Splign:2.1.0"
     exon            573..755
                     /gene="Dnaaf3"
                     /gene_synonym="6030429G01Rik; b2b1739Clo"
                     /inference="alignment:Splign:2.1.0"
     exon            756..881
                     /gene="Dnaaf3"
                     /gene_synonym="6030429G01Rik; b2b1739Clo"
                     /inference="alignment:Splign:2.1.0"
     exon            882..1004
                     /gene="Dnaaf3"
                     /gene_synonym="6030429G01Rik; b2b1739Clo"
                     /inference="alignment:Splign:2.1.0"
     exon            1005..1122
                     /gene="Dnaaf3"
                     /gene_synonym="6030429G01Rik; b2b1739Clo"
                     /inference="alignment:Splign:2.1.0"
     exon            1123..1234
                     /gene="Dnaaf3"
                     /gene_synonym="6030429G01Rik; b2b1739Clo"
                     /inference="alignment:Splign:2.1.0"
     exon            1235..1309
                     /gene="Dnaaf3"
                     /gene_synonym="6030429G01Rik; b2b1739Clo"
                     /inference="alignment:Splign:2.1.0"
     exon            1310..2236
                     /gene="Dnaaf3"
                     /gene_synonym="6030429G01Rik; b2b1739Clo"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2197..2202
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Dnaaf3"
                     /gene_synonym="6030429G01Rik; b2b1739Clo"
                     /note="hexamer: AATAAA"
     polyA_site      2215
                     /gene="Dnaaf3"
                     /gene_synonym="6030429G01Rik; b2b1739Clo"
                     /note="major polyA site"
ORIGIN      
        1 agagtgggcg aagcctctgg gaaactgttg tggtggcttc caggagctca gcacaggacc
       61 ctacctacgg atattttgaa gaataaagag cgatgaccac gcctgcgggc tcgggcaccg
      121 gttatggtag tgtgtcctgg tggggtctgt ccccggcgct ggacctacag gcagaaagtc
      181 ctcctgtaga cccagattca cagtcgaaaa cagagcgcaa ggtcccagaa ctggatgccc
      241 tgctgttagg ttctgtggat ggtagacaca tgctgcggac cctggccagg gcagcgctct
      301 ggcctctcag gagcttcaat ttttatgtgc tggagaataa tctggaagcg gtagcccgac
      361 acatgctgat cttcagtcta gccctagagg aacctgagaa gatggggctc caagagcgga
      421 gtgagacctt cctggagctg tgggggaacg cgctgctgcg accctcggta gctgccttcc
      481 tgcgcgctca ggctagccac ctggctaatc tggtcctgga gcctgatcgc ctggaggagc
      541 aactaccctg gcttagtctt cggctgctca agttccgcga gcgggatgcc ctggaggccg
      601 tgttccgttt ctggtctggt ggggagaagg gacctgaagt ctttcccatg agtcgccttt
      661 gggactcgag gttgcgccac tacctgggtt cccgctacga tgcccggcgt ggtgttgccg
      721 actgggacct acgcatgaag ctgcatgatc gaggggccca agttatccat atccaggaat
      781 tccgacgctg gcgggataca ggtgttgcct ttgaactcag agacttgagt gcttaccatg
      841 tgcccaacag gactctggca tcaggtcgcc tcctgagcca ccgtggggaa cgcgtggctg
      901 cgcgcggata ctggggggac atcgccacgg ggccctttat ggcttttggc atcgaggcgg
      961 acgaccaaag cctcttacgg acgagaaacg gacaaccagt caagactgcg agcgagatca
     1021 cgcagcacaa cgtcacagag ctgttccgag aagtagccgc ctggaggggc ccgagagcca
     1081 tccaggggaa tgtggaggag acagagtcgc ccgagccaga tgtgcctgct caagaaccct
     1141 tcactatcca ctttctgcct ctcgattctt cgcagactct ccaccacaag acttgctacc
     1201 agggccggtt ccagctcctc tacgtgtcct gtgggatggt ccatcttctc agccctgagc
     1261 tcggggcttg cgtggccccc ggagggaacc tggttgtgga attagctcgg tacttggtgg
     1321 acctgcggcc caaggagttg aaggcgttct ctgaccgcgt tgtagagata gcgcgggtgg
     1381 ctgggttcgc ccctcacact gcaaccaaac cctcggagac ttttgcgagg ttctacaagt
     1441 taggggactc cactccgggt ggcggagact cagctgtgga atctggaccc gcgccctcca
     1501 aagtggaatc tacccgcgcc cctctcccag aatcgataag tccgccccag gctaaccagg
     1561 ccccctctct agaggcgatg agcccacccc tggctgacct ggccccacct ctagagacaa
     1621 tgtgtccacc ccaggccaac caggcccctc ctctagaagc gttgagccca tccaaagctg
     1681 accagatccc acctctagag gcgatgagcc caccccaggc taagctagtc ctgcctgtag
     1741 aagcaatcag ccttccccaa gccgacctgg cctctcctcc ggaagtgata agcccactcc
     1801 aggaagctat ggcaacgtcc tgggtgaatg cacctccaaa acatgtaaca tgaaccccag
     1861 ggaccacgta gcccaccttt aactgctgaa gcaggcccag ggattgacat caccagctca
     1921 gcccacctgc atgcggtttt actctgcgtt ccttctcaac cccagggata tgactagaac
     1981 ttcaaattcc tttcctggaa ctctcggttg tactatttgg ggggtagggg tgagggtggg
     2041 ggatgggtcc tagactgtta tctgagactt atcctgacaa ggatcgaagg ctgaagggac
     2101 aaccctgggc tccagatcct ctcttttgtc ttgggccttt cttgacatgc tgcttttggg
     2161 aaggacaagg gcatagcctt ccttgaatgt gattcaaata aaaagcgcag ggtcacctct
     2221 gtgtgtcctg tcctcaaaaa aaaaaaaaaa aaaa
//
