LOCUS       NM_019872               1863 bp    mRNA    linear   ROD 05-AUG-2023
DEFINITION  Mus musculus DMRT-like family B with proline-rich C-terminal, 1
            (Dmrtb1), transcript variant 1, mRNA.
ACCESSION   NM_019872 XM_205469 XM_916034
VERSION     NM_019872.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1863)
  AUTHORS   Ono K, Hata K, Nakamura E, Ishihara S, Kobayashi S, Nakanishi M,
            Yoshida M, Takahata Y, Murakami T, Takenoshita S, Komori T,
            Nishimura R and Yoneda T.
  TITLE     Dmrt2 promotes transition of endochondral bone formation by linking
            Sox9 and Runx2
  JOURNAL   Commun Biol 4 (1), 326 (2021)
   PUBMED   33707608
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1863)
  AUTHORS   Metzakopian E, Bouhali K, Alvarez-Saavedra M, Whitsett JA, Picketts
            DJ and Ang SL.
  TITLE     Genome-wide characterisation of Foxa1 binding sites reveals several
            mechanisms for regulating neuronal differentiation in midbrain
            dopamine cells
  JOURNAL   Development 142 (7), 1315-1324 (2015)
   PUBMED   25804738
REFERENCE   3  (bases 1 to 1863)
  AUTHORS   Zhang T, Murphy MW, Gearhart MD, Bardwell VJ and Zarkower D.
  TITLE     The mammalian Doublesex homolog DMRT6 coordinates the transition
            between mitotic and meiotic developmental programs during
            spermatogenesis
  JOURNAL   Development 141 (19), 3662-3671 (2014)
   PUBMED   25249458
  REMARK    GeneRIF: The mammalian Doublesex homolog DMRT6 coordinates the
            transition between mitotic and meiotic developmental programs
            during spermatogenesis.
REFERENCE   4  (bases 1 to 1863)
  AUTHORS   Poulain M, Frydman N, Tourpin S, Muczynski V, Souquet B, Benachi A,
            Habert R, Rouiller-Fabre V and Livera G.
  TITLE     Involvement of doublesex and mab-3-related transcription factors in
            human female germ cell development demonstrated by xenograft and
            interference RNA strategies
  JOURNAL   Mol Hum Reprod 20 (10), 960-971 (2014)
   PUBMED   25082981
  REMARK    Erratum:[Mol Hum Reprod. 2015 Jul;21(7):615. Mucsynski, Vincent
            [Corrected to Muczynski, Vincent]. PMID: 26134375]
REFERENCE   5  (bases 1 to 1863)
  AUTHORS   Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K,
            Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre
            A, Pombero A, Rubenstein JLR, Wakeman WB, Hohmann J, Dee N, Sodt
            AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A,
            Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S,
            Wohnoutka P, Hawrylycz MJ, Puelles L and Jones AR.
  TITLE     A high-resolution spatiotemporal atlas of gene expression of the
            developing mouse brain
  JOURNAL   Neuron 83 (2), 309-323 (2014)
   PUBMED   24952961
REFERENCE   6  (bases 1 to 1863)
  AUTHORS   Hong CS, Park BY and Saint-Jeannet JP.
  TITLE     The function of Dmrt genes in vertebrate development: it is not
            just about sex
  JOURNAL   Dev Biol 310 (1), 1-9 (2007)
   PUBMED   17720152
  REMARK    Review article
REFERENCE   7  (bases 1 to 1863)
  AUTHORS   Murphy MW, Zarkower D and Bardwell VJ.
  TITLE     Vertebrate DM domain proteins bind similar DNA sequences and can
            heterodimerize on DNA
  JOURNAL   BMC Mol Biol 8, 58 (2007)
   PUBMED   17605809
  REMARK    Publication Status: Online-Only
REFERENCE   8  (bases 1 to 1863)
  AUTHORS   Kim S, Kettlewell JR, Anderson RC, Bardwell VJ and Zarkower D.
  TITLE     Sexually dimorphic expression of multiple doublesex-related genes
            in the embryonic mouse gonad
  JOURNAL   Gene Expr Patterns 3 (1), 77-82 (2003)
   PUBMED   12609607
REFERENCE   9  (bases 1 to 1863)
  AUTHORS   Ermekova KS, Zambrano N, Linn H, Minopoli G, Gertler F, Russo T and
            Sudol M.
  TITLE     The WW domain of neural protein FE65 interacts with proline-rich
            motifs in Mena, the mammalian homolog of Drosophila enabled
  JOURNAL   J Biol Chem 272 (52), 32869-32877 (1997)
   PUBMED   9407065
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL627259.8.
            
            [WARNING] On Oct 17, 2023 this sequence was replaced by
            NM_019872.3.
            
            On Jun 20, 2019 this sequence version replaced NM_019872.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN00849384
                              [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on computational evidence
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-651               AL627259.8         156212-156862       c
            652-860             AL627259.8         153278-153486       c
            861-1083            AL627259.8         151885-152107       c
            1084-1863           AL627259.8         148922-149701       c
FEATURES             Location/Qualifiers
     source          1..1863
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 50.18 cM"
     gene            1..1863
                     /gene="Dmrtb1"
                     /gene_synonym="Dmrt6; Prp13"
                     /note="DMRT-like family B with proline-rich C-terminal, 1"
                     /db_xref="GeneID:56296"
                     /db_xref="MGI:MGI:1927125"
     exon            1..651
                     /gene="Dmrtb1"
                     /gene_synonym="Dmrt6; Prp13"
                     /inference="alignment:Splign:2.1.0"
     CDS             69..1148
                     /gene="Dmrtb1"
                     /gene_synonym="Dmrt6; Prp13"
                     /note="doublesex and mab-3 related transcription factor 6;
                     proline-rich protein 13"
                     /codon_start=1
                     /product="doublesex- and mab-3-related transcription
                     factor B1"
                     /protein_id="NP_063925.1"
                     /db_xref="CCDS:CCDS51254.1"
                     /db_xref="GeneID:56296"
                     /db_xref="MGI:MGI:1927125"
                     /translation="MLRAPKCSRCRNHGYLVPVKGHTGKCRWKQCICDKCYLITERQK
                     IMAAQKVLRTQAAEEQVATVGTQGPQLPPRAPAAAATALSSSICPLPRAVPGGVGPGP
                     TATCFLERPPQAPSPGPSTFQLGPSGRPGPSTFQPGPGAPGGLRDRSSAWLPQLMPQA
                     PRPELCYPDQHLPVRPVPVPGPVRPVPRLPFADYGHPLRFKSDHVVGAGNPEREPFKQ
                     CPACVPVSPYQSFPLSEGQDSSSALGVPQQRGFRHVSCSPYHRSGLVSEPARDLQPTY
                     CSPPPPPPPPPPPPLPAPPPQPQQPHFLPPGYLSALHFLPPPPPPPSPPSFSLTYDTD
                     KENTNDQDAEAPTEPSQDSPQEQSN"
     exon            652..860
                     /gene="Dmrtb1"
                     /gene_synonym="Dmrt6; Prp13"
                     /inference="alignment:Splign:2.1.0"
     exon            861..1083
                     /gene="Dmrtb1"
                     /gene_synonym="Dmrt6; Prp13"
                     /inference="alignment:Splign:2.1.0"
     exon            1084..1863
                     /gene="Dmrtb1"
                     /gene_synonym="Dmrt6; Prp13"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 acttgctctg cagcttcggg aagtggtggc tgcgtttgga agcagagctt gcccagctag
       61 acgacaagat gcttcgcgcc cccaagtgct ctaggtgccg gaaccatggc tatctggtac
      121 cagtcaaggg ccatacgggc aaatgccgct ggaagcagtg catctgtgac aagtgctacc
      181 tgatcaccga gcgccagaag atcatggctg cccagaaggt tctcagaacc caagctgccg
      241 aggagcaggt ggcgaccgtg ggcacgcagg gtccccagct gcctcctagg gctccagcag
      301 cggcggccac cgccttgagc tccagcattt gcccactgcc tagggcggtt ccgggaggcg
      361 ttgggccagg ccccacggcc acttgcttcc tcgagaggcc cccgcaggcc ccgagcccag
      421 gcccgagcac cttccagctg ggcccaagtg gccgcccggg ccccagcacc ttccagcctg
      481 gaccaggggc ccccggggga ctgcgcgacc gttcctccgc gtggctgccc cagctcatgc
      541 cacaggcgcc caggccggag ctttgctacc cggatcagca cctgccagtg cggcccgtgc
      601 cagtgccagg gccagtgcgg cccgtgcccc gactgccgtt cgccgactac gggcatcctc
      661 tgagattcaa gtctgatcat gtggtaggag ctgggaatcc tgagagagag ccgttcaagc
      721 agtgccctgc ctgcgtccct gtttcaccct accagtcctt tccactttcg gaaggccagg
      781 attcatcctc tgctctgggg gtccctcaac aaagaggctt ccggcatgtc tcctgcagcc
      841 cctaccatag aagcggcttg gtgtcagagc cagccagaga cctgcagcca acctactgct
      901 caccgccgcc gccaccaccg ccgccacctc cgccaccact accagcaccc ccaccccagc
      961 cacagcagcc ccacttcctc ccaccaggct acctctctgc tctccacttc ctgccaccgc
     1021 cgccaccgcc accatctcca ccatctttct cgctgaccta cgatacagac aaggagaata
     1081 ccaatgacca ggatgcagaa gcacccaccg agcccagcca ggactctccc caggagcagt
     1141 ccaactaagc tgcaggccac ctggaaggcc accgggtggg gacgggcata gatggcgggg
     1201 gttatttttt caccatgttc atgttatata ggagaaagga tactgatagg tgtaagaagg
     1261 cagcgaattc ctactccagg ttagaagggc acaggtggtt tccaaggttc tctgggtcct
     1321 gggtgggtgt tgaagtggtg tacaaaggga gagaaagtct gggatgggca gggcttttga
     1381 agagtggggg ctggtgaaac acaagtttag aaatgaattt aaccatctga gccatgtatg
     1441 aaattcactt ctagaggtgg cccctgattt ccccaagcct cactcaggac agaaggcacc
     1501 attcagttca gccttctgcc ccctttgcct gacccccaag cctgggtacc gcaaacacca
     1561 aggcctccag acagtgcagg gcaggtgcca gggcctgaga tgctgacagc aggttctgca
     1621 gcatccacct ttgcccaaca ctgcctctcg tcctcttcca gagagtgagc gtcctgacaa
     1681 ctgagccact tcacttccct gggaaactca agcataggtg tcctttctca tttaaaaatg
     1741 tagattttag catttgatgt tcttatggtg gggaactcat gggcactgca gcagttctcg
     1801 gagcaaaaaa aatggccatt tgttctctgg ggacagtatt aaataaagtg agcattagaa
     1861 atc
//
