LOCUS       NM_010055               2609 bp    mRNA    linear   ROD 28-AUG-2024
DEFINITION  Mus musculus distal-less homeobox 3 (Dlx3), mRNA.
ACCESSION   NM_010055
VERSION     NM_010055.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2609)
  AUTHORS   Lee,D.J., Kim,P., Kim,H.Y., Park,J., Lee,S.J., An,H., Heo,J.S.,
            Lee,M.J., Ohshima,H., Mizuno,S., Takahashi,S., Jung,H.S. and
            Kim,S.J.
  TITLE     MAST4 regulates stem cell maintenance with DLX3 for epithelial
            development and amelogenesis
  JOURNAL   Exp Mol Med 56 (7), 1606-1619 (2024)
   PUBMED   38945953
  REMARK    GeneRIF: MAST4 regulates stem cell maintenance with DLX3 for
            epithelial development and amelogenesis.
REFERENCE   2  (bases 1 to 2609)
  AUTHORS   Gu,T., Guo,R., Fang,Y., Xiao,Y., Chen,L., Li,N., Ge,X.K., Shi,Y.,
            Wu,J., Yan,M., Yu,J. and Li,Z.
  TITLE     METTL3-mediated pre-miR-665/DLX3 m6A methylation facilitates the
            committed differentiation of stem cells from apical papilla
  JOURNAL   Exp Mol Med 56 (6), 1426-1438 (2024)
   PUBMED   38825638
  REMARK    GeneRIF: METTL3-mediated pre-miR-665/DLX3 m[6]A methylation
            facilitates the committed differentiation of stem cells from apical
            papilla.
REFERENCE   3  (bases 1 to 2609)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   4  (bases 1 to 2609)
  AUTHORS   Quilez,S., Dumontier,E., Baim,C., Kam,J. and Cloutier,J.F.
  TITLE     Loss of Neogenin alters branchial arch development and leads to
            craniofacial skeletal defects
  JOURNAL   Front Cell Dev Biol 12, 1256465 (2024)
   PUBMED   38404688
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 2609)
  AUTHORS   Qu,F., Li,W., Xu,J., Zhang,R., Ke,J., Ren,X., Meng,X., Qin,L.,
            Zhang,J., Lu,F., Zhou,X., Luo,X., Zhang,Z., Wang,M., Wu,G., Pei,D.,
            Chen,J., Cui,G., Suo,S. and Peng,G.
  TITLE     Three-dimensional molecular architecture of mouse organogenesis
  JOURNAL   Nat Commun 14 (1), 4599 (2023)
   PUBMED   37524711
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 2609)
  AUTHORS   Scherer,S.W., Heng,H.H., Robinson,G.W., Mahon,K.A., Evans,J.P. and
            Tsui,L.C.
  TITLE     Assignment of the human homolog of mouse Dlx3 to chromosome
            17q21.3-q22 by analysis of somatic cell hybrids and fluorescence in
            situ hybridization
  JOURNAL   Mamm Genome 6 (4), 310-311 (1995)
   PUBMED   7613049
REFERENCE   7  (bases 1 to 2609)
  AUTHORS   Weiss,K.M., Ruddle,F.H. and Bollekens,J.
  TITLE     Dlx and other homeobox genes in the morphological development of
            the dentition
  JOURNAL   Connect Tissue Res 32 (1-4), 35-40 (1995)
   PUBMED   7554933
REFERENCE   8  (bases 1 to 2609)
  AUTHORS   Robinson,G.W., Wray,S. and Mahon,K.A.
  TITLE     Spatially restricted expression of a member of a new family of
            murine Distal-less homeobox genes in the developing forebrain
  JOURNAL   New Biol 3 (12), 1183-1194 (1991)
   PUBMED   1687503
REFERENCE   9  (bases 1 to 2609)
  AUTHORS   Sakano,H., Maki,R., Kurosawa,Y., Roeder,W. and Tonegawa,S.
  TITLE     Two types of somatic recombination are necessary for the generation
            of complete immunoglobulin heavy-chain genes
  JOURNAL   Nature 286 (5774), 676-683 (1980)
   PUBMED   6774258
REFERENCE   10 (bases 1 to 2609)
  AUTHORS   Eicher,E.M., Stern,R.H., Womack,J.E., Davisson,M.T., Roderick,T.H.
            and Reynolds,S.C.
  TITLE     Evolution of mammalian carbonic anhydrase loci by tanden
            duplication: close linkage of Car-1 and Car-2 to the centromere
            region of chromosome 3 of the mouse
  JOURNAL   Biochem Genet 14 (7-8), 651-660 (1976)
   PUBMED   825106
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL606480.11.
            
            On Jun 4, 2019 this sequence version replaced NM_010055.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC058852.2, U79738.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849383
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-530               AL606480.11        174037-174566
            531-721             AL606480.11        175628-175818
            722-2609            AL606480.11        177329-179216
FEATURES             Location/Qualifiers
     source          1..2609
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 59.01 cM"
     gene            1..2609
                     /gene="Dlx3"
                     /gene_synonym="Dlx-3"
                     /note="distal-less homeobox 3"
                     /db_xref="GeneID:13393"
                     /db_xref="MGI:MGI:94903"
     exon            1..530
                     /gene="Dlx3"
                     /gene_synonym="Dlx-3"
                     /inference="alignment:Splign:2.1.0"
     exon            531..721
                     /gene="Dlx3"
                     /gene_synonym="Dlx-3"
                     /inference="alignment:Splign:2.1.0"
     exon            722..2609
                     /gene="Dlx3"
                     /gene_synonym="Dlx-3"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2581..2586
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Dlx3"
                     /gene_synonym="Dlx-3"
                     /note="hexamer: ATTAAA"
     polyA_site      2609
                     /gene="Dlx3"
                     /gene_synonym="Dlx-3"
                     /note="major polyA site"
ORIGIN      
        1 agcatttgac tgtggcttgg gacgcggaga gaggcacgca gcgactgacc gacagccggc
       61 gatggtctaa gcgcccctcg gccaccccct cccccagacg cgaccgcgtc ctgccctcgc
      121 cctctggaca cacaccccca cctgggctcc tccgcccgtt cggcgctcct cggaggaggc
      181 ccggggtgtt gcggcgctcg ccagcatgag cggctccttc gatcgcaagc tcagcagcat
      241 cctcaccgac atctccagct cgctcagctg ccatgcgggc tccaaggact cgcccaccct
      301 gcccgaatct acagtcactg acctgggcta ttacagcgct cctcagcatg actactactc
      361 gggccagccc tacggccaga cggtgaaccc ctacacctac caccaccagt tcaatctcaa
      421 tgggctcgca ggcaccggcg cttactcgcc caagtcggaa tatacctacg ggggatccta
      481 taggcagtac ggagcgtacc gggagcagcc tttgcctgcc caggacccag tgtcggtgaa
      541 agaggagccg gaagccgagg ttcgcatggt gaacggcaag cccaaaaagg tccgaaagcc
      601 gcgaacgatc tactccagct atcagctggc tgccctgcag cgccgtttcc agaaagccca
      661 gtatctggcc ttgcctgagc gcgccgagct agctgcacag ctgggcctca cacaaacaca
      721 ggtgaaaatc tggttccaga accgccgctc caagttcaaa aagctctata agaatgggga
      781 ggtgccgctg gaacacagcc ccaacaacag tgactccatg gcctgcaact caccgccgtc
      841 accagcactc tgggacacat cttcccattc cacgccagcc cctgcccgca atccgctgcc
      901 cccaccgctc ccatacagtg cctcccccaa ctacctggac gaccccacca actcctggta
      961 ccacacacag aacctcagtg gaccccactt acagcagcag cctcctcagc cggctaccct
     1021 gcaccatgcc tcccctgggc ccccgcctaa ccctggggct gtgtactgag tacccacctg
     1081 gcctgcgccc ctccacgaag gaccccctcc aggaccaggc agaaggtgcc ctgtcctagc
     1141 gacactcagg aatcattgag gggcacaggg ggaaagactc ccttccctct cccttgtccc
     1201 ttcttccagg gacccaacaa cctccagatg acaaatgcat ggaccgagga tgccccccaa
     1261 tctccctccc cttgcttaga ctggggtgcc ctccagacgg cgaggagttc taccccagtg
     1321 gggacagcac atgctctctg ctccaggaac ccggattgcc tctagatggc tcatcgcttt
     1381 ccagcttttc aaacacagta gagacctcca aaatgggagc cagagtgttt gcaggtccac
     1441 ctgtgctggg gcaccaggcg ccacggattc cagcacagcc agacctaaag caccaagggg
     1501 caactataca ttcttgagcc actctttaaa agacattgga cattacatca tggctgatcc
     1561 tcaagatggg ggggggctga cctagtcccc actgttctcc agccctcatt aggatttgag
     1621 ggtccaaacc aaagaaaact cccccaaatg agggaacctt tgatatccag ggcttccaag
     1681 ggaagactta aaggagccat ccctccgccc cttccctggg gaaaaggatt gcccatgtcc
     1741 ttttccaagg acctgtttct ccttccatgt acaggacttt gcacaagtct ggttttaaaa
     1801 gctgttgaaa cctaggacga caatgggcat tgttaacagt taggaccaaa tccactcctc
     1861 tctgggcggg cagctctgct ctgccctgac cctgctcacc ccttcgtttt gttttgtttt
     1921 gtttttctcc cagtaagttt gcagtcttgg gggacgggct caaaccccaa ctctctacag
     1981 agatagacca ggcaagacac cccccactca gacaccccct tcgtggcagc tttggaaaca
     2041 ggttgtccgt tctgctgcag gattcaagtg aggatccagg agacaagagg aggcctagaa
     2101 ctcagtgcct taggggtaag gctgtcagct tggacggctg gtaccagtgc ctctccctgg
     2161 cccaggcatc ccccaaagct aactttcttc tgccccctga tgtggtaaaa catcgaagaa
     2221 aggagaggtg acagactgta gttatatata tatagtatgg tttttttttg ttgttgttgt
     2281 ttcttttttt tttttttttt taagagcaac caagagaagc aggtcccctc ccttgtggtt
     2341 tcctatttat gtgaccctgt tcctcctgga ccaatctccc tgtgttgcaa gtcgaaagag
     2401 ggatgtgggc tcctgctgga tttgggtttc gtgggaagtg aaggagtaag aagagacaga
     2461 cgtggtgggt ctccgagtcc caccccaaag ggacaggact gaagccagct cccacccctc
     2521 cccagccttc tcatttctgc tttcttactg gaccagtctt tatatataat gttaataaaa
     2581 attaaaaaaa aagaagaaga agaaaataa
//
