LOCUS       NM_001252433            4675 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus discs large MAGUK scaffold protein 1 (Dlg1),
            transcript variant 2, mRNA.
ACCESSION   NM_001252433
VERSION     NM_001252433.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4675)
  AUTHORS   Li,X., Peng,Z., Jiang,L., Zhang,P., Yang,P., Yuan,Z. and Cheng,J.
  TITLE     Dlg1 deletion in microglia ameliorates chronic restraint stress
            induced mice depression-like behavior
  JOURNAL   Front Pharmacol 14, 1124845 (2023)
   PUBMED   36909184
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4675)
  AUTHORS   Castillo-Azofeifa,D., Wald,T., Reyes,E.A., Gallagher,A.,
            Schanin,J., Vlachos,S., Lamarche-Vane,N., Bomidi,C., Blutt,S.,
            Estes,M.K., Nystul,T. and Klein,O.D.
  TITLE     A DLG1-ARHGAP31-CDC42 axis is essential for the intestinal stem
            cell response to fluctuating niche Wnt signaling
  JOURNAL   Cell Stem Cell 30 (2), 188-206 (2023)
   PUBMED   36640764
REFERENCE   3  (bases 1 to 4675)
  AUTHORS   Bahouth,S.W., Nooh,M.M. and Mancarella,S.
  TITLE     Involvement of SAP97 anchored multiprotein complexes in regulating
            cardiorenal signaling and trafficking networks
  JOURNAL   Biochem Pharmacol 208, 115406 (2023)
   PUBMED   36596415
  REMARK    GeneRIF: Involvement of SAP97 anchored multiprotein complexes in
            regulating cardiorenal signaling and trafficking networks.
            Review article
REFERENCE   4  (bases 1 to 4675)
  AUTHORS   Romero,D.M., Poirier,K., Belvindrah,R., Moutkine,I., Houllier,A.,
            LeMoing,A.G., Petit,F., Boland,A., Collins,S.C., Soiza-Reilly,M.,
            Yalcin,B., Chelly,J., Deleuze,J.F., Bahi-Buisson,N. and Francis,F.
  TITLE     Novel role of the synaptic scaffold protein Dlgap4 in ventricular
            surface integrity and neuronal migration during cortical
            development
  JOURNAL   Nat Commun 13 (1), 2746 (2022)
   PUBMED   35585091
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 4675)
  AUTHORS   Peng,Z., Li,X., Li,J., Dong,Y., Gao,Y., Liao,Y., Yan,M., Yuan,Z.
            and Cheng,J.
  TITLE     Dlg1 Knockout Inhibits Microglial Activation and Alleviates
            Lipopolysaccharide-Induced Depression-Like Behavior in Mice
  JOURNAL   Neurosci Bull 37 (12), 1671-1682 (2021)
   PUBMED   34490521
REFERENCE   6  (bases 1 to 4675)
  AUTHORS   Rafael,J.A., Hutchinson,T.L., Lumeng,C.N., Marfatia,S.M.,
            Chishti,A.H. and Chamberlain,J.S.
  TITLE     Localization of Dlg at the mammalian neuromuscular junction
  JOURNAL   Neuroreport 9 (9), 2121-2125 (1998)
   PUBMED   9674605
REFERENCE   7  (bases 1 to 4675)
  AUTHORS   Lin,L., Sahr,K.E. and Chishti,A.H.
  TITLE     Identification of the mouse homologue of human discs large and rat
            SAP97 genes
  JOURNAL   Biochim Biophys Acta 1362 (1), 1-5 (1997)
   PUBMED   9434093
REFERENCE   8  (bases 1 to 4675)
  AUTHORS   Kalcheva,I., Elliott,R.W., Dalziel,M. and Lau,J.T.
  TITLE     The gene encoding beta-galactoside alpha2,6-sialyltransferase maps
            to mouse chromosome 16
  JOURNAL   Mamm Genome 8 (8), 619-620 (1997)
   PUBMED   9250875
REFERENCE   9  (bases 1 to 4675)
  AUTHORS   Peters,L.L., Ciciotte,S.L., Lin,L. and Chishti,A.H.
  TITLE     The mouse homolog of the Drosophila discs large tumor suppressor
            gene maps to chromosome 16
  JOURNAL   Mamm Genome 7 (8), 619-620 (1996)
   PUBMED   8829552
REFERENCE   10 (bases 1 to 4675)
  AUTHORS   Burgess,D.L., Rafael,J.A., Meisler,M.H. and Chamberlain,J.S.
  TITLE     Dlgh1, a mouse homolog of the drosophila discs-large gene, is
            located on chromosome 16
  JOURNAL   Mamm Genome 7 (8), 623-624 (1996)
   PUBMED   8678991
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BU058018.1, AY159380.1 and AC129214.5.
            
            Transcript Variant: This variant (2) lacks an exon and uses an
            alternate splice site in the coding region, but maintains the
            reading frame, compared to variant 1. The encoded isoform (2) is
            shorter than isoform 1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY159380.1, SRR17253011.7336125.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849380
                                           [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-348               BU058018.1         1-348
            349-1727            AY159380.1         9-1387
            1728-1728           AC129214.5         100453-100453
            1729-4669           AY159380.1         1389-4329
            4670-4675           AC129214.5         161113-161118
FEATURES             Location/Qualifiers
     source          1..4675
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="16"
                     /map="16 22.4 cM"
     gene            1..4675
                     /gene="Dlg1"
                     /gene_synonym="B130052P05Rik; Dlgh1; E-dlg/SAP97;
                     mKIAA4187; SAP-97; SAP97"
                     /note="discs large MAGUK scaffold protein 1"
                     /db_xref="GeneID:13383"
                     /db_xref="MGI:MGI:107231"
     exon            1..387
                     /gene="Dlg1"
                     /gene_synonym="B130052P05Rik; Dlgh1; E-dlg/SAP97;
                     mKIAA4187; SAP-97; SAP97"
                     /inference="alignment:Splign:2.1.0"
     exon            388..437
                     /gene="Dlg1"
                     /gene_synonym="B130052P05Rik; Dlgh1; E-dlg/SAP97;
                     mKIAA4187; SAP-97; SAP97"
                     /inference="alignment:Splign:2.1.0"
     CDS             419..3100
                     /gene="Dlg1"
                     /gene_synonym="B130052P05Rik; Dlgh1; E-dlg/SAP97;
                     mKIAA4187; SAP-97; SAP97"
                     /note="isoform 2 is encoded by transcript variant 2; disks
                     large homolog 1; embryo-dlg/synapse-associated protein 97;
                     discs, large homolog 1"
                     /codon_start=1
                     /product="disks large homolog 1 isoform 2"
                     /protein_id="NP_001239362.1"
                     /db_xref="GeneID:13383"
                     /db_xref="MGI:MGI:107231"
                     /translation="MPVRKQDTQRALHLLEEYRSKLSQTEDRQLRSSIERVINIFQSN
                     LFQALIDIQEFYEVTLLDNPKCVDHSKQCEPVQPVTTWEIASLPSTAVTSETLPGSLS
                     PPVEKYRYQDEEVLPPEHISPQVTNEVLGPELVHVSEKNLSEIENVHGFVSHSHISPI
                     KANPPPVLVNTDSLETPTYVNGTDADYEYEEITLERGNSGLGFSIAGGTDNPHIGDDS
                     SIFITKIITGGAAAQDGRLRVNDCILRVNEADVRDVTHSKAVEALKEAGSIVRLYVKR
                     RKPASEKIMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGKLQI
                     GDKLLAVNSVCLEEVTHEEAVTALKNTSDFVYLKVAKPTSMYINDGYAPPDITNSSSQ
                     SVDNHVSPSSCLGQTPTSPARYSPISKAVLGDDEITREPRKVVLHRGSTGLGFNIVGG
                     EDGEGIFISFILAGGPADLSGELRKGDRIISVNSVDLRAASHEQAAAALKNAGQAVTI
                     VAQYRPEEYSRFEAKIHDLREQMMNSSVSSGSGSLRTSQKRSLYVRALFDYDKTKDSG
                     LPSQGLNFRFGDILHVINASDDEWWQARQVTPDGESDEVGVIPSKRRVEKKERARLKT
                     VKFNSKTRGDKGSFNDKRKKNLFSRKFPFYKNKDQSEQETSDADQHVTSNASDSESSY
                     RGQEEYVLSYEPVNQQEVNYTRPVIILGPMKDRVNDDLISEFPDKFGSCVPHTTRPKR
                     DYEVDGRDYHFVTSREQMEKDIQEHKFIEAGQYNNHLYGTSVQSVRAVAEKGKHCILD
                     VSGNAIKRLQIAQLYPISIFIKPKSMENIMEMNKRLTEEQARKTFERAMKLEQEFTEH
                     FTAIVQGDTLEDIYNQVKQIIEEQSGPYIWVPAKEKL"
     exon            438..569
                     /gene="Dlg1"
                     /gene_synonym="B130052P05Rik; Dlgh1; E-dlg/SAP97;
                     mKIAA4187; SAP-97; SAP97"
                     /inference="alignment:Splign:2.1.0"
     exon            570..736
                     /gene="Dlg1"
                     /gene_synonym="B130052P05Rik; Dlgh1; E-dlg/SAP97;
                     mKIAA4187; SAP-97; SAP97"
                     /inference="alignment:Splign:2.1.0"
     exon            737..901
                     /gene="Dlg1"
                     /gene_synonym="B130052P05Rik; Dlgh1; E-dlg/SAP97;
                     mKIAA4187; SAP-97; SAP97"
                     /inference="alignment:Splign:2.1.0"
     exon            902..955
                     /gene="Dlg1"
                     /gene_synonym="B130052P05Rik; Dlgh1; E-dlg/SAP97;
                     mKIAA4187; SAP-97; SAP97"
                     /inference="alignment:Splign:2.1.0"
     exon            956..1006
                     /gene="Dlg1"
                     /gene_synonym="B130052P05Rik; Dlgh1; E-dlg/SAP97;
                     mKIAA4187; SAP-97; SAP97"
                     /inference="alignment:Splign:2.1.0"
     exon            1007..1131
                     /gene="Dlg1"
                     /gene_synonym="B130052P05Rik; Dlgh1; E-dlg/SAP97;
                     mKIAA4187; SAP-97; SAP97"
                     /inference="alignment:Splign:2.1.0"
     exon            1132..1301
                     /gene="Dlg1"
                     /gene_synonym="B130052P05Rik; Dlgh1; E-dlg/SAP97;
                     mKIAA4187; SAP-97; SAP97"
                     /inference="alignment:Splign:2.1.0"
     exon            1302..1438
                     /gene="Dlg1"
                     /gene_synonym="B130052P05Rik; Dlgh1; E-dlg/SAP97;
                     mKIAA4187; SAP-97; SAP97"
                     /inference="alignment:Splign:2.1.0"
     exon            1439..1583
                     /gene="Dlg1"
                     /gene_synonym="B130052P05Rik; Dlgh1; E-dlg/SAP97;
                     mKIAA4187; SAP-97; SAP97"
                     /inference="alignment:Splign:2.1.0"
     exon            1584..1704
                     /gene="Dlg1"
                     /gene_synonym="B130052P05Rik; Dlgh1; E-dlg/SAP97;
                     mKIAA4187; SAP-97; SAP97"
                     /inference="alignment:Splign:2.1.0"
     exon            1705..1861
                     /gene="Dlg1"
                     /gene_synonym="B130052P05Rik; Dlgh1; E-dlg/SAP97;
                     mKIAA4187; SAP-97; SAP97"
                     /inference="alignment:Splign:2.1.0"
     exon            1862..1964
                     /gene="Dlg1"
                     /gene_synonym="B130052P05Rik; Dlgh1; E-dlg/SAP97;
                     mKIAA4187; SAP-97; SAP97"
                     /inference="alignment:Splign:2.1.0"
     exon            1965..2079
                     /gene="Dlg1"
                     /gene_synonym="B130052P05Rik; Dlgh1; E-dlg/SAP97;
                     mKIAA4187; SAP-97; SAP97"
                     /inference="alignment:Splign:2.1.0"
     exon            2080..2256
                     /gene="Dlg1"
                     /gene_synonym="B130052P05Rik; Dlgh1; E-dlg/SAP97;
                     mKIAA4187; SAP-97; SAP97"
                     /inference="alignment:Splign:2.1.0"
     exon            2257..2326
                     /gene="Dlg1"
                     /gene_synonym="B130052P05Rik; Dlgh1; E-dlg/SAP97;
                     mKIAA4187; SAP-97; SAP97"
                     /inference="alignment:Splign:2.1.0"
     exon            2327..2423
                     /gene="Dlg1"
                     /gene_synonym="B130052P05Rik; Dlgh1; E-dlg/SAP97;
                     mKIAA4187; SAP-97; SAP97"
                     /inference="alignment:Splign:2.1.0"
     exon            2424..2465
                     /gene="Dlg1"
                     /gene_synonym="B130052P05Rik; Dlgh1; E-dlg/SAP97;
                     mKIAA4187; SAP-97; SAP97"
                     /inference="alignment:Splign:2.1.0"
     exon            2466..2516
                     /gene="Dlg1"
                     /gene_synonym="B130052P05Rik; Dlgh1; E-dlg/SAP97;
                     mKIAA4187; SAP-97; SAP97"
                     /inference="alignment:Splign:2.1.0"
     exon            2517..2618
                     /gene="Dlg1"
                     /gene_synonym="B130052P05Rik; Dlgh1; E-dlg/SAP97;
                     mKIAA4187; SAP-97; SAP97"
                     /inference="alignment:Splign:2.1.0"
     exon            2619..2791
                     /gene="Dlg1"
                     /gene_synonym="B130052P05Rik; Dlgh1; E-dlg/SAP97;
                     mKIAA4187; SAP-97; SAP97"
                     /inference="alignment:Splign:2.1.0"
     exon            2792..2901
                     /gene="Dlg1"
                     /gene_synonym="B130052P05Rik; Dlgh1; E-dlg/SAP97;
                     mKIAA4187; SAP-97; SAP97"
                     /inference="alignment:Splign:2.1.0"
     exon            2902..2993
                     /gene="Dlg1"
                     /gene_synonym="B130052P05Rik; Dlgh1; E-dlg/SAP97;
                     mKIAA4187; SAP-97; SAP97"
                     /inference="alignment:Splign:2.1.0"
     exon            2994..4675
                     /gene="Dlg1"
                     /gene_synonym="B130052P05Rik; Dlgh1; E-dlg/SAP97;
                     mKIAA4187; SAP-97; SAP97"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4647..4652
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Dlg1"
                     /gene_synonym="B130052P05Rik; Dlgh1; E-dlg/SAP97;
                     mKIAA4187; SAP-97; SAP97"
                     /note="hexamer: AATAAA"
     polyA_site      4669
                     /gene="Dlg1"
                     /gene_synonym="B130052P05Rik; Dlgh1; E-dlg/SAP97;
                     mKIAA4187; SAP-97; SAP97"
                     /note="major polyA site"
ORIGIN      
        1 gcgaggttcc gggggtgggg cggcccggag gcgagcggac gagcaggggc cgcgggccgc
       61 ggcgagcggg cgagcggcgg cggccgaggc ggagagagcg gcgcgggggt gcggccgccg
      121 aagggggagc tcctcccccg tcccctcacc ccctcagctg agctcggggc ggggcggggt
      181 acgtggagcg gggccgggcg gggaagctgc tccgagtccg gccggagcgc acccggggcg
      241 cccgcgtacg ccgctcgcgg gaactttgcg gcggagccgc aggtgtggag gccgcggagg
      301 ggggtgcatg agcggcgcgg agagcggcgg ctgtccggtc cggcccctgc tggagtcgcc
      361 gccgggagga gacgaacgag gaaccaggtg tgtgccgcct tcctgattct ggagaaaaat
      421 gccggtccgg aagcaagata cccagagagc attgcatctg ttggaagaat atcgatcgaa
      481 actaagccaa actgaagaca gacaactcag aagttccata gagcgggtta ttaacatatt
      541 tcagagcaac ctctttcagg ctttaataga tattcaagaa ttttatgaag tgaccttact
      601 tgataatcca aaatgtgtgg atcattcaaa gcagtgtgaa ccagttcagc ctgtgactac
      661 ttgggagatt gccagccttc caagcactgc cgtgacgtca gaaaccctgc ccggcagcct
      721 tagccctcca gtagagaaat accggtatca ggatgaagag gtacttcctc ctgagcatat
      781 ttctccacaa gtcacaaatg aggtgctagg tccagaactg gtccatgtct cagagaagaa
      841 cctgtcagag attgagaatg tccatggatt tgtttctcat tctcatatct caccaataaa
      901 ggcaaatcct cctccagtgc tggtcaacac agacagctta gagacaccaa cttatgttaa
      961 tggcactgat gcagattatg aatatgagga aatcacactt gaaaggggaa attcgggtct
     1021 tggtttcagc attgcaggag gtacagacaa cccacacatt ggagatgact caagtatttt
     1081 catcaccaaa attatcacag gcggagcggc tgcccaggat ggaagattgc gggtaaatga
     1141 ctgtatactg agagtaaatg aagcagacgt tcgtgatgta acccacagca aagcagtgga
     1201 ggcattaaaa gaagctggat ctattgtgcg attgtatgtg aaaaggcgga agccagcatc
     1261 agaaaaaatc atggaaataa agctcattaa aggtcctaaa ggtcttgggt tcagcattgc
     1321 tggaggtgtt ggaaatcagc acattcctgg tgataacagc atctatgtaa ccaaaataat
     1381 tgaaggaggt gcagcacaca aggatggcaa gcttcagatt ggagataagc ttctagcagt
     1441 gaacagtgtg tgtttagaag aagttactca tgaagaagca gtgactgcct taaagaatac
     1501 atctgatttt gtttatttga aagtggcaaa accaacaagt atgtatataa atgatggcta
     1561 tgcaccacct gacatcacta attcttcttc tcaatctgtt gacaaccatg tcagcccgtc
     1621 ctcctgcttg ggccagacgc caacgtcacc agccaggtac tcacccattt ctaaagctgt
     1681 gctcggagat gacgagatca ctagggaacc tagaaaagtt gttcttcatc gtggctcaac
     1741 aggacttggt tttaacattg tgggaggtga agatggagaa gggattttta tctccttcat
     1801 ccttgctggc ggacctgctg atctaagtgg agagctcaga aaaggagatc gcatcatatc
     1861 ggtgaacagt gttgacctca gagctgcaag tcacgaacaa gcagcagctg cactaaagaa
     1921 cgcaggccaa gccgtcacca tcgttgcgca atatcgaccc gaagagtaca gtcgttttga
     1981 agctaaaatc catgacttac gggagcagat gatgaatagc agtgtcagtt cagggtcagg
     2041 gtctcttcga accagccaga agcgctccct ctatgtcaga gccctctttg attatgacaa
     2101 gactaaggac agcgggcttc ccagtcaagg actgaacttc cgctttggag acatcctcca
     2161 tgtcatcaat gcttctgacg acgagtggtg gcaagccagg caggtcaccc cagacgggga
     2221 gagtgacgaa gtcggagtga ttcctagtaa acgaagagtt gagaagaagg aacgagcccg
     2281 attaaaaacg gtcaaattca attctaaaac aagaggagat aaagggtcat tcaatgacaa
     2341 gcgtaaaaag aacctctttt cccgaaaatt tcccttctac aagaacaagg accagagtga
     2401 acaggaaacg agtgatgctg accagcacgt aacttctaat gccagcgata gtgaaagtag
     2461 ttaccgtggt caagaagaat atgttttatc ttatgagcca gtgaatcaac aagaagttaa
     2521 ttatacccga ccagtcatca tattaggacc tatgaaagac agagtaaatg atgacttaat
     2581 ctcagaattt cctgacaaat ttggatcctg tgtccctcat acaactagac cgaagcgtga
     2641 ctatgaggtg gatggacgag attatcattt tgtgacttca agggaacaga tggaaaagga
     2701 tattcaggag cataagttca ttgaagccgg ccagtataac aaccatctgt atgggacgag
     2761 cgtgcagtcc gtgcgagcag tggcagagaa gggcaaacat tgtatccttg atgtgtctgg
     2821 aaatgccata aagaggttgc agattgcaca gctttatcca atatctattt ttattaaacc
     2881 caaatccatg gaaaatatca tggaaatgaa caagcgccta acagaagagc aggccagaaa
     2941 aacatttgag agagccatga agctggagca ggagttcact gagcatttca cagctattgt
     3001 ccagggagac acgctggagg acatttacaa ccaagtgaaa cagatcatcg aagaacagtc
     3061 tgggccttac atctgggtcc cagcgaaaga aaagctatga agacggatgt tgttctttct
     3121 tttttccatg gtctcatctc ttgccctgtt gtggagtctg tcttcggtgt cctccacact
     3181 gacacagatc ccctcctcat ggtcggcagt tgtgcccgtt ttttgacatc tgtgtccctt
     3241 catgttgcat catctgtact attctgtgtt actcttggtt tctggccact tttcagaatg
     3301 aagatgaatg gcctgaccag ctatctaggg tttggggaga tgcaaaattg taaaattcct
     3361 taatgtttaa gggaaagtta actttaagag attttcagaa aagctttata tacattcttt
     3421 tccaatttca gtacaaatga aagaaaagtg gttttaatca gtgatttagt ggaccttgag
     3481 caactgtgca cgcttcactc taatagcatg gtttggccag tgtattagct ctcaagttct
     3541 ttcctcaatt gacttctgct attaaagtaa tgatttcatt aaaaacaaat aagaaaaata
     3601 gggatttatt tcaaaattaa tgtctgagtt aactcataat ttcaggagtt gtttgttatt
     3661 cgtggcaggt ctttattgtg tgccctccca tgggacacgt gccaggacta accatggagg
     3721 tgtgcagctc tgtgggaagt gagtggctct cgagccttgt ccgtacactg tggttacggc
     3781 tctgtcgcgg tcaaagaact cactttacac acagaactgc agacaagaaa gggtttcggt
     3841 ggacttgtag caatcatggc agtgggaagg agtccaattc atagcctaaa attttaatgt
     3901 atgcttaggg aggggtcaga ttttaatgac tattttaccc acaataactg cctattttgt
     3961 tataataaaa tatatataaa tatatataaa actttcttta actaaactct gtaactatgg
     4021 gaattatttt ctttacatag ttgcacacac aaacatatat atatatattt aaaatatatt
     4081 tttcttttgc cacctacttc taactttttg tttggttttt aaattaaata ttaattgatg
     4141 agacttaccg tccttaatca tgtgaactga agacaagtgt ccggtggcgg tgaggagaaa
     4201 cctctaggag attaggttgt gagtaggcgc caagcctgtt ctcctctttc ctacagaagt
     4261 tccagaaggt tcctaggttt cctgtcagtg ttgtgttctt gtcatggagt ttgatttcgg
     4321 tcctctgcct ttcctcctag ttctcctcat tttattaata gacagacaaa ctccattttt
     4381 gcgactcccc gagacacttc atcttgcgta gctgcgctga actagaattg cacaggtgtt
     4441 aagtaaacga cttgagaaag gttagtgaga ggcagatgcc ttcagaagtc actttctcta
     4501 gtccattatt aatatcattt ggcttccctt tgctctttgg aactgtttat tcgatacgtg
     4561 attttggcaa ctctttaaaa tttcctaaat gagtactggg ttgtaaagaa ttatccattc
     4621 catttatgag aaagaggaga acagctaata aactttattg taaaatccat atgtt
//
