LOCUS       NM_177117               5784 bp    mRNA    linear   ROD 09-JUN-2024
DEFINITION  Mus musculus deleted in lung and esophageal cancer 1 (Dlec1),
            transcript variant 1, mRNA.
ACCESSION   NM_177117 XM_486268 XM_916519
VERSION     NM_177117.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5784)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 5784)
  AUTHORS   Okitsu,Y., Nagano,M., Yamagata,T., Ito,C., Toshimori,K., Dohra,H.,
            Fujii,W. and Yogo,K.
  TITLE     Dlec1 is required for spermatogenesis and male fertility in mice
  JOURNAL   Sci Rep 10 (1), 18883 (2020)
   PUBMED   33144677
  REMARK    GeneRIF: Dlec1 is required for spermatogenesis and male fertility
            in mice.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 5784)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24643. PMID: 29144450]
REFERENCE   4  (bases 1 to 5784)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC055818.9.
            
            On Jun 17, 2019 this sequence version replaced NM_177117.4.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: partial sample support SAMN00849374, SAMN00849381
                              [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-417               AC055818.9         127074-127490       c
            418-568             AC055818.9         124047-124197       c
            569-679             AC055818.9         119788-119898       c
            680-867             AC055818.9         117755-117942       c
            868-1085            AC055818.9         117373-117590       c
            1086-1164           AC055818.9         114957-115035       c
            1165-1252           AC055818.9         110264-110351       c
            1253-1426           AC055818.9         109023-109196       c
            1427-1563           AC055818.9         108075-108211       c
            1564-1656           AC055818.9         106762-106854       c
            1657-1747           AC055818.9         105789-105879       c
            1748-1910           AC055818.9         105081-105243       c
            1911-2103           AC055818.9         103653-103845       c
            2104-2162           AC055818.9         102953-103011       c
            2163-2331           AC055818.9         102415-102583       c
            2332-2425           AC055818.9         101888-101981       c
            2426-2556           AC055818.9         101605-101735       c
            2557-2715           AC055818.9         101341-101499       c
            2716-2855           AC055818.9         99861-100000        c
            2856-3009           AC055818.9         95377-95530         c
            3010-3120           AC055818.9         94705-94815         c
            3121-3245           AC055818.9         93234-93358         c
            3246-3425           AC055818.9         92616-92795         c
            3426-3496           AC055818.9         92390-92460         c
            3497-3648           AC055818.9         91810-91961         c
            3649-3767           AC055818.9         91107-91225         c
            3768-3838           AC055818.9         90553-90623         c
            3839-4049           AC055818.9         87211-87421         c
            4050-4158           AC055818.9         87015-87123         c
            4159-4284           AC055818.9         86808-86933         c
            4285-4379           AC055818.9         86598-86692         c
            4380-4464           AC055818.9         86331-86415         c
            4465-4668           AC055818.9         85918-86121         c
            4669-4830           AC055818.9         83822-83983         c
            4831-4984           AC055818.9         82867-83020         c
            4985-5108           AC055818.9         82519-82642         c
            5109-5784           AC055818.9         81753-82428         c
FEATURES             Location/Qualifiers
     source          1..5784
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 71.32 cM"
     gene            1..5784
                     /gene="Dlec1"
                     /gene_synonym="D630005C06Rik"
                     /note="deleted in lung and esophageal cancer 1"
                     /db_xref="GeneID:320256"
                     /db_xref="MGI:MGI:2443671"
     exon            1..417
                     /gene="Dlec1"
                     /gene_synonym="D630005C06Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             7..5232
                     /gene="Dlec1"
                     /gene_synonym="D630005C06Rik"
                     /note="isoform 1 is encoded by transcript variant 1;
                     deleted in lung and esophageal cancer protein 1 homolog"
                     /codon_start=1
                     /product="deleted in lung and esophageal cancer protein 1
                     homolog isoform 1"
                     /protein_id="NP_796091.2"
                     /db_xref="CCDS:CCDS52963.1"
                     /db_xref="GeneID:320256"
                     /db_xref="MGI:MGI:2443671"
                     /translation="MDSESKEEQQCTASSAVMSSLETQFLSVPHQLESASLSWSIRKS
                     LHSSTVLMDDCHFGFPTRSLRAGFHALPPLPEPQTLRLRPASLRTQEISHLLARVFRN
                     LYTAQVIGDDLSDSLIKARGSEDARHEEFLDQLQQARAIYKQRLDEAAMLERHIMQAR
                     ARDIAETEHTTKQSRLQVVETPVKLPPVKTAFRWCLDSKLMRKHHLISTEDYYTDPVP
                     FCPAPKDKSTLGCSKLTFSCEQRFLRKSELDREAEEHCRQLTECDDFEYTVDSLGSIS
                     KAKERTTDSVKKTSRPKNKKWMEHLQVPQRALDRRLLASMENRNHFLKNPRFFPPNTP
                     HGGKSLIVPLSKPERRASLNAEPEWSCTDAPVFLAKPSVGFFTDYEIGPVYEMVIALQ
                     NTTSTSRFLRVLPPSSPYFALGLGMFPGKGGIVAPGMTCQYIVQFIPDCLGDFDDFIL
                     VETQSPHTLVIPLQARRPPPVLTLSPVLDCGHCLIGGVKITKFICKNVGFSVGKFCIM
                     PQKSWPPPSFRAVATTGFVEQPPFGVMPSVFELAPGYAILLEVLFLPTGLGQAEETFI
                     IVCDNCQIKEVVVVGTGQLVALDLIHISGGKNEPDPGELKDLTAQYFIRFEPENVQST
                     AKKQLIIRNATHVELAFHWQIMKPNLQPLMPGETHSSDSIKCHPDRETAFSIIPEKGI
                     LESHSDQEFILSFSPYKLKCFHSVLQMVLEAVPEPLSSGLENLGDYSYSVDDMIVLEI
                     EVKGLAEPFQVLLEPYALIIPGENYIGITVKKDFKMWNNSKSPIRYMWGKISHCHIIE
                     VEPCTGVIEPNEVGDFELNLTGGVPGPTSQDLECEIKDSPCPVVLHIEASFKGPALTI
                     DVPALQFGLLRLGKKASISIQIRNVSQLSAVWHLKESPVCLAERDEDVSPFDIEPFCG
                     QLLPLGECRVTITLEASQCQRLQTVLELEVENGSGSYLPVYAEVQQPHVYLKNSHLEF
                     SNLYLGVSTKSRTTLVNGTLLPTRFHWGKLLGPQADLCTMTVSPTQGLLGPSEELQLT
                     LELTTHTEEKLTNLVLLCHVSGMEKPLVLGISGKPLGLQVTISIVESDGSSTTSTTQE
                     ELRLDFGSKVPLRTPVIRHIILTNCSPIQTPFTLTLEYFGSSQDSLYKKTSVPDVPPA
                     LLKTARIQQHVAKKERLDFVESMLSHRKGAAFLPHISQGMLGAYQELCIDITGCANMW
                     GEYWDELLCVVGDLPVTVIPVYMAVVGCPISSLRNTCYSVAPFQKEPITRFGTQISGG
                     DTVTRSLRLYNSSHCDIRLDWETYIPEEKADRLLELLVFYGPPFPLRDQDGSEIVCPE
                     TSEASLPGSPCPSNVSVSSHTVPSTVSSGGGGGTRAEEQIMSVILQRHEAVPAGHIYR
                     ISPKQLVIPAGDHRTIYISFTPTVLDPGVMHKVGYTGYALGFMSLDKETDRQIPGRMR
                     RLQDFAVSPLRLDLNGHVRHAQLHVELDSSGYLEFWCQASDLIPQNPCSGVLSDRITT
                     RHLKLTNTTEILYDFQARVSRPFFISQGGASWDSRAPHQCEEGTASTGQWLMIRPQDN
                     MLVDVSFSLSLELLSYQKLSADQMLPGVDIQESENGERKMVFTQNLLLGFTNQTVQEV
                     PLRAFVTLPAPQLSTSWVDFGTCLVNQQHTRQIYLMNLSCCLSYWTVLLGQEEPARED
                     HAFGVSPGSGLLEARATNAPPTSSPLQVFFNPRSSILYESTLVVEGVLSEKPCVLRLR
                     GLGSYDERYVKFHEF"
     exon            418..568
                     /gene="Dlec1"
                     /gene_synonym="D630005C06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            569..679
                     /gene="Dlec1"
                     /gene_synonym="D630005C06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            680..867
                     /gene="Dlec1"
                     /gene_synonym="D630005C06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            868..1085
                     /gene="Dlec1"
                     /gene_synonym="D630005C06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1086..1164
                     /gene="Dlec1"
                     /gene_synonym="D630005C06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1165..1252
                     /gene="Dlec1"
                     /gene_synonym="D630005C06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1253..1426
                     /gene="Dlec1"
                     /gene_synonym="D630005C06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1427..1563
                     /gene="Dlec1"
                     /gene_synonym="D630005C06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1564..1656
                     /gene="Dlec1"
                     /gene_synonym="D630005C06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1657..1747
                     /gene="Dlec1"
                     /gene_synonym="D630005C06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1748..1910
                     /gene="Dlec1"
                     /gene_synonym="D630005C06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1911..2103
                     /gene="Dlec1"
                     /gene_synonym="D630005C06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2104..2162
                     /gene="Dlec1"
                     /gene_synonym="D630005C06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2163..2331
                     /gene="Dlec1"
                     /gene_synonym="D630005C06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2332..2425
                     /gene="Dlec1"
                     /gene_synonym="D630005C06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2426..2556
                     /gene="Dlec1"
                     /gene_synonym="D630005C06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2557..2715
                     /gene="Dlec1"
                     /gene_synonym="D630005C06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2716..2855
                     /gene="Dlec1"
                     /gene_synonym="D630005C06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2856..3009
                     /gene="Dlec1"
                     /gene_synonym="D630005C06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3010..3120
                     /gene="Dlec1"
                     /gene_synonym="D630005C06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3121..3245
                     /gene="Dlec1"
                     /gene_synonym="D630005C06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3246..3425
                     /gene="Dlec1"
                     /gene_synonym="D630005C06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3426..3496
                     /gene="Dlec1"
                     /gene_synonym="D630005C06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3497..3648
                     /gene="Dlec1"
                     /gene_synonym="D630005C06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3649..3767
                     /gene="Dlec1"
                     /gene_synonym="D630005C06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3768..3838
                     /gene="Dlec1"
                     /gene_synonym="D630005C06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3839..4049
                     /gene="Dlec1"
                     /gene_synonym="D630005C06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            4050..4158
                     /gene="Dlec1"
                     /gene_synonym="D630005C06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            4159..4284
                     /gene="Dlec1"
                     /gene_synonym="D630005C06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            4285..4379
                     /gene="Dlec1"
                     /gene_synonym="D630005C06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            4380..4464
                     /gene="Dlec1"
                     /gene_synonym="D630005C06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            4465..4668
                     /gene="Dlec1"
                     /gene_synonym="D630005C06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            4669..4830
                     /gene="Dlec1"
                     /gene_synonym="D630005C06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            4831..4984
                     /gene="Dlec1"
                     /gene_synonym="D630005C06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            4985..5108
                     /gene="Dlec1"
                     /gene_synonym="D630005C06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            5109..5784
                     /gene="Dlec1"
                     /gene_synonym="D630005C06Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5758..5763
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Dlec1"
                     /gene_synonym="D630005C06Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      5784
                     /gene="Dlec1"
                     /gene_synonym="D630005C06Rik"
                     /note="major polyA site"
ORIGIN      
        1 gttgccatgg attccgagag caaggaagag cagcaatgca cagcttcctc ggccgttatg
       61 tcgtccttgg agacccagtt tttgtctgtc ccacaccagc tcgagtccgc cagtctcagc
      121 tggtccatca ggaagtcctt gcattcctcg accgtcttaa tggatgattg ccatttcggc
      181 ttccctacgc ggtccctccg cgccgggttc cacgcgctcc ctccactccc ggagccgcag
      241 acgctgcgtc tacgccccgc ctcgttgcgc acgcaggaaa tctcacatct gcttgcccga
      301 gtcttccgaa acttgtacac cgcccaggtg atcggagatg acttgagcga cagtttgatc
      361 aaggcccgcg gcagtgagga tgcgcgccac gaagagttcc ttgaccagct gcagcaggcg
      421 cgagccatct ataaacagcg tctggatgaa gccgccatgt tggagagaca tatcatgcag
      481 gcccgtgcac gggatattgc agaaacagaa cacaccacca aacagagcag actacaggtt
      541 gtggagaccc ctgtcaaact gcccccagtg aagacagcct tcaggtggtg tctagacagc
      601 aagttaatgc gaaaacatca cttaatctct acagaggatt actacactga tcccgtgccg
      661 ttttgcccag cacccaaaga caaatccacc cttggatgtt caaagctgac gtttagctgt
      721 gagcagcgtt tcctgcgcaa gtcagagctg gacagggagg ctgaggagca ctgcaggcag
      781 ctcacagagt gtgacgactt tgagtacacc gtggacagct tgggctccat ctcgaaggcc
      841 aaagagagga ccacagattc tgtcaagaag acaagcaggc caaagaataa gaagtggatg
      901 gaacacctgc aggtgccgca gagagccctg gacaggcggc tgctcgccag catggagaac
      961 aggaatcact tcctgaaaaa ccctcggttt ttcccgccta acacaccaca tggaggcaag
     1021 tctctcatcg tccctttgag caagccagag agaagagcat ccctgaatgc agagcctgag
     1081 tggagctgta cagatgcccc cgtgttcctg gcgaagccat cagttggatt tttcacagat
     1141 tacgaaattg gacccgttta cgagatggtg atcgctctac agaacaccac ctccaccagc
     1201 cgattcttgc gtgtcctccc accgtcctct ccgtacttcg ctctgggact tgggatgttc
     1261 ccaggaaaag gcggaatagt ggctcccggg atgacctgcc agtacatcgt ccagttcatc
     1321 ccggactgtc ttggcgattt tgatgatttc attttggtgg agacacagtc tccccacacg
     1381 ctggtaatcc ccctgcaggc ccggagaccg ccgccagtgc tgaccttgtc accagtgttg
     1441 gactgcggcc actgcctcat tggaggggtg aagataacca aattcatctg caaaaatgtg
     1501 ggcttcagcg tcggcaaatt ctgtatcatg ccccaaaaga gctggccgcc accgagtttc
     1561 cgggctgttg caactactgg ctttgtagag cagcctcctt ttggagtaat gccttccgtg
     1621 tttgagctgg ccccagggta cgccatactg ttggaggtct tgttcctccc tactggccta
     1681 ggacaggcag aagagacctt catcatcgtg tgtgacaact gtcagataaa ggaggtggtc
     1741 gtcgtaggga cagggcagct ggtggctttg gatctgattc atatttctgg tggaaaaaat
     1801 gagccagacc caggagagct gaaagattta acagcccagt actttatccg gtttgagcct
     1861 gaaaacgtcc agtccaccgc aaagaagcag ctcatcatca gaaatgctac acacgtggag
     1921 ctggccttcc actggcagat catgaaaccc aacctgcagc ctctgatgcc tggagagaca
     1981 cacagctcag acagcatcaa atgccaccct gacagggaga cagccttctc catcatcccc
     2041 gagaagggca tcctcgagtc ccactcggac caagagttca tcctgagttt ttcaccttac
     2101 aagctcaagt gtttccacag tgtactgcaa atggttctag aagctgtgcc cgagcccttg
     2161 agctcagggt tggagaacct gggggactac tcctactcag tggatgacat gatcgtcctg
     2221 gaaatcgagg tgaaaggctt ggcggaaccc ttccaggtcc ttttagagcc gtacgccctc
     2281 atcatccctg gggagaacta cattggcatc accgtgaaga aagattttaa gatgtggaac
     2341 aacagcaagt cacccatcag atacatgtgg gggaagatca gccactgcca tatcatcgaa
     2401 gtggagccct gcactggggt gatagagccc aatgaggtcg gagattttga gttaaaccta
     2461 acgggtgggg tgcctggccc aaccagccag gacctggagt gtgaaatcaa agactcacca
     2521 tgcccggtgg tactccacat tgaggcctca tttaagggac ctgccttgac cattgatgtc
     2581 ccagcccttc agtttggtct gcttcgcctg ggaaagaagg cttccatctc catccagatc
     2641 cggaatgtca gccagctgtc cgccgtgtgg catttgaagg agagcccagt ctgcctggca
     2701 gagagagatg aggatgtgtc ccccttcgac atcgagcctt tctgcggcca gcttctccct
     2761 ctgggggagt gcagagtgac catcaccctt gaggcctccc agtgtcagcg gctgcagaca
     2821 gtcctggagc tggaagtgga gaacgggtcc gggagctacc ttcccgtgta cgctgaggtg
     2881 cagcagcctc acgtgtacct gaagaacagc cacttggagt tcagcaacct ctacctgggc
     2941 gtgtccacaa agtcaaggac cacgctggtc aatggcacac tcctgcccac ccggttccac
     3001 tggggaaagc ttctgggacc tcaagcagat ttgtgcacaa tgacagtctc tcccacacag
     3061 ggcctgctgg gccccagtga agagctccaa ctcaccttgg agttgacgac ccacacagag
     3121 gaaaagctga ccaatttggt tctcctttgt cacgtgtctg gcatggagaa gccgctggtc
     3181 ctgggcatct ctgggaagcc cctgggactt caggtgacca tctccatagt ggaatctgac
     3241 ggaagcagca ccaccagcac tacacaggag gagctgcgct tggacttcgg ctcgaaggtg
     3301 ccactgagga cgcccgtgat tcgccatatc atcctgacaa actgctcccc gatacagacc
     3361 ccattcaccc tcacactgga gtacttcggg agctcccagg acagcctgta caagaagacc
     3421 agcgtccctg acgtgcctcc tgccctgctg aagacagcac gcatccagca gcacgtggcc
     3481 aagaaggaaa ggctggactt tgtggagagc atgttatctc acaggaaagg agctgccttc
     3541 cttccccaca tctcccaggg catgctggga gcctaccagg agctatgtat tgacatcaca
     3601 ggctgtgcca acatgtgggg cgagtactgg gatgagctcc tctgcgtggt gggagacctg
     3661 ccggtcactg tcatcccggt atacatggcc gtggtgggct gccctatcag ctccctgagg
     3721 aatacgtgct acagtgtggc cccattccag aaggagccta tcaccaggtt tgggacccag
     3781 atctctggag gagatacagt caccagatct ctccgtctgt ataactccag tcactgtgac
     3841 atccgcctag actgggagac ctacatccca gaagaaaagg cggaccggct gctggagctg
     3901 cttgtgtttt atgggccacc cttcccactg cgagatcaag acggcagtga gattgtgtgc
     3961 cctgagacct cggaggccag cttaccaggg tctccatgcc cctccaatgt ctcagtgtct
     4021 agccacactg tcccctcaac ggtgagcagt ggcggcggcg gcggcaccag ggccgaagag
     4081 cagatcatgt ctgtcatcct gcagaggcac gaggcagtgc ccgccggcca catataccgt
     4141 atcagcccca agcagttggt catcccagct ggagaccaca ggaccatcta catctccttc
     4201 acgcccacgg tgctcgaccc aggggtcatg cacaaggtgg ggtatactgg ctatgccctg
     4261 ggcttcatga gcttggataa ggagacagac agacagattc caggccgaat gcgacgcctt
     4321 caggactttg ccgtgagccc cctgagactg gatctgaatg gccacgtgag acacgcgcag
     4381 ctgcacgtcg agctggacag cagtggctac ttggaattct ggtgccaggc cagcgacctt
     4441 atcccccaaa atccctgcag tggggtgcta agtgaccgga ttaccacccg ccatctgaaa
     4501 ctgaccaaca ccactgaaat cctgtatgac ttccaggccc gggtctccag gcccttcttc
     4561 atttctcaag gtggggccag ctgggacagc agagcccctc atcagtgtga agaagggacg
     4621 gcctccacag gccagtggct gatgatccgt cctcaggaca acatgctggt ggatgtgtcc
     4681 ttctcactgt ccctggaact gctgtcctat cagaaactct cggccgacca gatgttgccc
     4741 ggagtggata ttcaggagag cgagaacgga gagagaaaga tggtgttcac acagaaccta
     4801 ctcctgggct tcaccaacca gactgttcag gaggtgcccc tgcgggcctt tgtgaccctg
     4861 ccagcgccac agctctccac cagctgggtg gacttcggga cctgtctcgt gaaccagcag
     4921 cacacccggc agatctacct gatgaacctc agctgctgcc tgagctactg gacggtgctg
     4981 ttgggacaag aggaaccagc cagggaggat catgcgtttg gggtctcccc aggcagtgga
     5041 ctgctggagg cccgagccac caatgcaccc cctacctcca gcccacttca ggtgttcttc
     5101 aaccctagga gcagcatcct ctatgaatct acactggtgg tggaaggcgt gctgagcgag
     5161 aagccctgtg tcctgaggct tcggggccta ggctcttacg atgaaagata cgtgaaattc
     5221 catgagttct gaggctctgt agtgcccagc cccagcccca gccccagccc cagccccagc
     5281 cccagtccta cccccagccc cagccccagc cccagcccca gccctacccc cagccccagc
     5341 tgaggccatc aatctggctc agggttgagg agcagggctg ccgaacaggt acacgggcta
     5401 tggggctgga ggccctcctt aggatgaagg atctccttct gaggtgtggt gtgagccagg
     5461 ccctgtgtga cagttttcag ggccaccacc agcagagtgg ctatgacagt cactacaaag
     5521 accgtccaca attccaacaa agcaagagct ggaccctgga tgaaatgact gcaaccaaga
     5581 tcagttcacc cacgtttact gtgcccatca catccaccat tcatgaaggc accgtcccac
     5641 agaaatgaat gttgtcctgt ggtcaagcat agcatgcact gtctttggtt cgaccgagag
     5701 aaccggattg gatgccccag tgcccacgtg tacccatgct gcaattacat tttctaaatt
     5761 aaagtgctgt gacacacccc tcca
//
