LOCUS       NM_175228               1922 bp    mRNA    linear   ROD 03-JUN-2024
DEFINITION  Mus musculus divergent protein kinase domain 2B (Dipk2b),
            transcript variant 1, mRNA.
ACCESSION   NM_175228
VERSION     NM_175228.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1922)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK163928.1 and AK085770.1.
            
            On Sep 1, 2015 this sequence version replaced NM_175228.3.
            
            Transcript Variant: This variant (1) represents the protein-coding
            transcript.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK085770.1, BC118515.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849382 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-123               AK163928.1         2-124
            124-1922            AK085770.1         2-1800
FEATURES             Location/Qualifiers
     source          1..1922
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="X"
                     /map="X 13.73 cM"
     gene            1..1922
                     /gene="Dipk2b"
                     /gene_synonym="4930578C19Rik"
                     /note="divergent protein kinase domain 2B"
                     /db_xref="GeneID:75905"
                     /db_xref="MGI:MGI:1923155"
     exon            1..374
                     /gene="Dipk2b"
                     /gene_synonym="4930578C19Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             136..1443
                     /gene="Dipk2b"
                     /gene_synonym="4930578C19Rik"
                     /note="UPF0672 protein CXorf36 homolog; deleted in
                     autism-related protein 1 homolog"
                     /codon_start=1
                     /product="divergent protein kinase domain 2B precursor"
                     /protein_id="NP_780437.1"
                     /db_xref="CCDS:CCDS30038.1"
                     /db_xref="GeneID:75905"
                     /db_xref="MGI:MGI:1923155"
                     /translation="MESQWRGAAATAFHQHWLARLLLWVSTLSCSFSLPASLPPSLVP
                     RVRSSYTMGKTFLGLDKCNACIGTSICKKFFKEEIRFDNSLASHLGLPPQDLHSYAAN
                     YSDDSKTWRPVEISQLVSRYQIEISDRRICASVSAPKTCSIERILQKTGRFQKWLQAK
                     RLTPDLVQGLPSPFLRCPSQRLLDRVVRRYAEVVDAGSIFMDHFTAGDKLRLLYTLAV
                     NAHPIILQIFPGAEGWPMPRYLGSCGRFLVSTSTRPLQEFYDASPEQAADLAYQLLRV
                     LESLRSNDLNYFFYFTHVDAGMFGIFDNGHLFIRDASALGIIDKQEGSQAAARTGENE
                     DIFSCLVSDCQIQLSSCDTVPEKQSLVLVCQQLLPQLLQGKFPSPVQKEIDSALSLCS
                     KDNSTDLEVLGATSWLKDILRSLRTCDPRFAYRYPDCKYNDRF"
     exon            375..639
                     /gene="Dipk2b"
                     /gene_synonym="4930578C19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            640..813
                     /gene="Dipk2b"
                     /gene_synonym="4930578C19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            814..1102
                     /gene="Dipk2b"
                     /gene_synonym="4930578C19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1103..1922
                     /gene="Dipk2b"
                     /gene_synonym="4930578C19Rik"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agaaacctca gaggcttgga cagggtcagc atcctgaaac cagctgcttt gggcagcttc
       61 ctttctggtc aggcctaacc tctgtgcagc tctgagtgta ccgctgacca ccacggctgc
      121 aacacagagc gcaggatgga gtcccaatgg cgtggtgctg cagctaccgc cttccaccaa
      181 cactggctag cccggctgct gctgtgggtc tcaaccctga gctgttcttt ctccttgcca
      241 gcttctctcc ctccttctct ggtacccaga gtcagaagca gctacactat gggaaagaca
      301 ttcctcggtc ttgataaatg caatgcctgc atcgggacat ccatttgtaa gaagttcttt
      361 aaagaagaaa taaggtttga caactcactg gcttcccacc tgggactgcc tcctcaggac
      421 ttgcattctt atgctgcaaa ttactcagat gactctaaaa cctggcgccc tgtggagatt
      481 tctcaactgg tcagcaggta ccaaattgag atctctgaca ggaggatctg tgcctctgta
      541 tcagcaccaa agacctgcag cattgagcgc atccttcaga aaacagggag gttccagaaa
      601 tggctgcagg ccaagcgcct cacacctgac ctggtgcagg gcctgcccag tcccttcctg
      661 cgctgccctt cacaaagact cttggaccgt gtggttcgac gctatgctga agtagtcgat
      721 gctggcagca tcttcatgga ccacttcact gccggtgaca agctgcgtct cctctacacg
      781 ctggctgtca acgcacaccc catcatcctg cagatcttcc ctggagcaga gggctggcca
      841 atgcccaggt acctgggctc ctgtggtaga ttcctggtca gtaccagtac cagaccattg
      901 caagaatttt atgatgcctc tccagagcaa gctgctgacc ttgcctacca actcctcagg
      961 gtcctggaat ccctgaggag caatgacttg aactatttct tctatttcac ccatgttgat
     1021 gcaggcatgt ttggcatctt tgacaatggg catctgttca tccgagatgc cagtgcgcta
     1081 ggcatcatcg acaagcagga aggcagccaa gcagctgcca ggactggaga aaatgaagac
     1141 atttttagct gcctggtttc tgactgccag atccagctgt cctcctgtga cactgtccct
     1201 gagaagcaaa gccttgtgct ggtgtgtcag cagctgctgc ctcaacttct ccagggaaag
     1261 tttccctccc ctgtgcaaaa ggaaatagac tctgctctca gcctgtgcag caaggataac
     1321 agcacagacc tagaagttct tggggctacc agttggctga aggacatctt aagatctttg
     1381 agaacctgtg atcctagatt tgcctaccgt tacccagact gcaagtataa tgatagattc
     1441 tgagtggctg aagggacaat ctgcaagctc ttccatgtcc ttggttgaat tactgccaaa
     1501 ttataagaag caattccatt ttgaatattt aagtacatta atttcctaag aaacacacaa
     1561 aacttgtggg agaaactttg acactgcatg tttgacctca ctggctagaa caccatggca
     1621 tagtcaggag gtagacacag gaagaccagg tgtgaacact caatatcttt gaacctccat
     1681 tttctgtata ttttaccaga cttttgcaag tttaaagaaa acagaggtgt aaggagccca
     1741 gaaatacaat tgtgaccaac aaaacatgtt ccagaaacac acgcagatag ggcaagtaag
     1801 aaagtcccat atgttgggag gctagtgtag gtagagggca aggtgaaggc agggctttga
     1861 gccattggaa ctcaaggccc ccattcctac tctcctgcat ctccgagaag agactataag
     1921 cc
//
