LOCUS       NM_025447               2545 bp    mRNA    linear   ROD 05-AUG-2024
DEFINITION  Mus musculus DIM1 rRNA methyltransferase and ribosome maturation
            factor (Dimt1), mRNA.
ACCESSION   NM_025447
VERSION     NM_025447.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2545)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BF608861.1, AK011544.1 and AK078186.1.
            
            On Mar 11, 2009 this sequence version replaced NM_025447.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK011544.1, AK146188.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-627               BF608861.1         12-638
            628-2081            AK011544.1         585-2038
            2082-2545           AK078186.1         2876-3339
FEATURES             Location/Qualifiers
     source          1..2545
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 58.06 cM"
     gene            1..2545
                     /gene="Dimt1"
                     /gene_synonym="1500031M22Rik; Dimt1l"
                     /note="DIM1 rRNA methyltransferase and ribosome maturation
                     factor"
                     /db_xref="GeneID:66254"
                     /db_xref="MGI:MGI:1913504"
     exon            1..155
                     /gene="Dimt1"
                     /gene_synonym="1500031M22Rik; Dimt1l"
                     /inference="alignment:Splign:2.1.0"
     CDS             77..1018
                     /gene="Dimt1"
                     /gene_synonym="1500031M22Rik; Dimt1l"
                     /EC_number="2.1.1.183"
                     /note="probable dimethyladenosine transferase; 18S rRNA
                     dimethylase; S-adenosylmethionine-6-N',N'-adenosyl(rRNA)
                     dimethyltransferase; 18S rRNA
                     (adenine(1779)-N(6)/adenine(1780)-N(6))-
                     dimethyltransferase; probable 18S rRNA dimethylase; DIM1
                     dimethyladenosine transferase 1 homolog; probable
                     S-adenosylmethionine-6-N',N'-adenosyl(rRNA)
                     dimethyltransferase; probable 18S rRNA
                     (adenine(1779)-N(6)/adenine(1780)-N(6))-
                     dimethyltransferase; DIM1 dimethyladenosine transferase
                     1-like"
                     /codon_start=1
                     /product="dimethyladenosine transferase"
                     /protein_id="NP_079723.1"
                     /db_xref="CCDS:CCDS26758.1"
                     /db_xref="GeneID:66254"
                     /db_xref="MGI:MGI:1913504"
                     /translation="MPKAKSAASSRRRDRQEQRRELKRAGGLMFNTGIGQHILKNPLI
                     VNSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKKVVACELDPRLVAELHKRVQGTP
                     LASKLQVLVGDVLKSDLPFFDACVANLPYQISSPFVFKLLLHRPFFRCAILMFQREFA
                     LRLVAKPGDKLYCRLSINTQLLARVDHLMKVGKNNFRPPPKVESSVVRIEPKNPPPPI
                     NFQEWDGLVRITFVRKNKTLSAAFKSSAVQQLLEKNYRIHCSVQNTVIPEDFSIADKI
                     QQILTSTGFSDKRARSMDIDDFIRLLHGFNAEGIHFS"
     exon            156..229
                     /gene="Dimt1"
                     /gene_synonym="1500031M22Rik; Dimt1l"
                     /inference="alignment:Splign:2.1.0"
     exon            230..316
                     /gene="Dimt1"
                     /gene_synonym="1500031M22Rik; Dimt1l"
                     /inference="alignment:Splign:2.1.0"
     exon            317..378
                     /gene="Dimt1"
                     /gene_synonym="1500031M22Rik; Dimt1l"
                     /inference="alignment:Splign:2.1.0"
     exon            379..472
                     /gene="Dimt1"
                     /gene_synonym="1500031M22Rik; Dimt1l"
                     /inference="alignment:Splign:2.1.0"
     exon            473..522
                     /gene="Dimt1"
                     /gene_synonym="1500031M22Rik; Dimt1l"
                     /inference="alignment:Splign:2.1.0"
     exon            523..646
                     /gene="Dimt1"
                     /gene_synonym="1500031M22Rik; Dimt1l"
                     /inference="alignment:Splign:2.1.0"
     exon            647..739
                     /gene="Dimt1"
                     /gene_synonym="1500031M22Rik; Dimt1l"
                     /inference="alignment:Splign:2.1.0"
     exon            740..804
                     /gene="Dimt1"
                     /gene_synonym="1500031M22Rik; Dimt1l"
                     /inference="alignment:Splign:2.1.0"
     exon            805..868
                     /gene="Dimt1"
                     /gene_synonym="1500031M22Rik; Dimt1l"
                     /inference="alignment:Splign:2.1.0"
     exon            869..975
                     /gene="Dimt1"
                     /gene_synonym="1500031M22Rik; Dimt1l"
                     /inference="alignment:Splign:2.1.0"
     exon            976..2545
                     /gene="Dimt1"
                     /gene_synonym="1500031M22Rik; Dimt1l"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1214..1219
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Dimt1"
                     /gene_synonym="1500031M22Rik; Dimt1l"
                     /note="hexamer: TATAAA"
     polyA_site      1241
                     /gene="Dimt1"
                     /gene_synonym="1500031M22Rik; Dimt1l"
                     /note="major polyA site"
     regulatory      1960..1965
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Dimt1"
                     /gene_synonym="1500031M22Rik; Dimt1l"
                     /note="hexamer: AATAAA"
     polyA_site      1991
                     /gene="Dimt1"
                     /gene_synonym="1500031M22Rik; Dimt1l"
     regulatory      2520..2525
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Dimt1"
                     /gene_synonym="1500031M22Rik; Dimt1l"
                     /note="hexamer: ATTAAA"
     polyA_site      2542
                     /gene="Dimt1"
                     /gene_synonym="1500031M22Rik; Dimt1l"
ORIGIN      
        1 gtcgtgacgg cgactgaggg cgacttccac gcggttcccg gctgctttcg cttggcacag
       61 ggactcctcc gagaagatgc cgaaggccaa gtccgcagcg agtagccgcc ggcgggatcg
      121 tcaggagcag cgccgggagc tgaagcgagc tggaggactc atgttcaaca cagggatcgg
      181 acaacacatt ttgaaaaatc ctctaattgt taacagcatc atcgataagg ctgctttaag
      241 acctaccgat gtggtgctgg aagttgggcc tgggactggc aatatgactg tcaagctgtt
      301 agaaaaggcc aaaaaggtag ttgcctgtga acttgatcca aggctagtag ctgaacttca
      361 caaaagagtt cagggcacgc ctctggccag caaactccag gtcctggtgg gagatgtact
      421 gaaatcagat ttgccattct ttgatgcttg tgtggcaaac ttgccttatc agatctcctc
      481 tccctttgtc ttcaagttgc tgctccaccg gccatttttc agatgtgcta tacttatgtt
      541 tcagagagag tttgctcttc gattggttgc caagcctgga gataaattat actgtagact
      601 ctccatcaac acacagcttt tagcacgcgt ggaccatcta atgaaggtgg ggaagaataa
      661 cttcagaccg ccccccaagg tggagtccag cgtggtcagg atagaaccta agaatccgcc
      721 accaccaatc aattttcagg aatgggacgg cttagtaagg atcacttttg ttcggaaaaa
      781 caagacactg tccgctgcat tcaaatcaag tgcagtacaa caactgttgg aaaaaaatta
      841 cagaattcac tgttcagtac agaatactgt aataccagaa gatttcagta tagcagataa
      901 aatacagcaa atcctaacca gcacaggttt cagtgacaaa cgggcccgtt ccatggacat
      961 agatgacttc atcaggttgc tacatggatt caatgcagaa ggcatccact tctcctagcc
     1021 atttgaaaac tattttttca agaccaagaa aaaatgaaat tatacaatcc tactatttga
     1081 gaatacaacc aattttgttc tacaggacat catttaaatt atttaataat acttttttac
     1141 catttattat cctgtatgtg aaaggtggtt gggtatatat atatatgtat gtatgtatgt
     1201 gtattatatt atatataaat aataccctgc cctttgtagt agacctagtg ttttatatat
     1261 aaatataaaa ataatggtct ttaagtttga aagccacaga cacacacaac atacacttaa
     1321 gctttctaac aatttattgt atgaagacgt tacttttatt cactatttta gactgtgagg
     1381 ttcacgtagg cctacagctc actcaactag tcagaaagcc cccaatgtga cttttcttca
     1441 cacaccttca ccctacgtgt tattatttgc ctcttgcaac acaaacaaca tcataattct
     1501 gggagctgag tctgctgcaa tgacagtaca ggcaagttct gcataagact acctgtaaaa
     1561 tgcagaagct tagaaagtaa aaactcatgt taaatcacat atttccttaa gggagacaag
     1621 atctacaatt ttcagattta gaaaaactct ggagggtttt gtcaatcaaa taggtggtct
     1681 cattaattta tgattcattt cctttcttga atgagagggt cttttggagg ttgactttaa
     1741 tctcagactc ttgcctcagc ctcctaaata aattctgggg ttatacttgt gcaaagtaag
     1801 ttttccagtt ttagttttca gctttttaaa agaacagact aaaactacag gttcctggtt
     1861 attcctgact tctagataat taaaattcta ctacctggtg tttcttttta agctatttaa
     1921 aaattgtcag ataaaagata aatgctgttt atatatttta ataaattagc tgttttattt
     1981 atataaggaa actaaactag cttctctatt tatacttaaa acttaaaagg aatatctcca
     2041 attacttgag aaaaagaatg ctaagtaaac ttaatataaa ttgctcgcct acagtttttc
     2101 cttcaaaatc cagtttctaa gtcatatagt aaacacttat tatagtagct atgaatagtt
     2161 agcagccttt aagtttgaga catttctaaa gaatatttaa tctagaacaa aaacatttgc
     2221 ttagctgcaa aagcagcttt tgtcatattg atcagaactg ttcttaaagt ttgtttattg
     2281 tcagaacaac tttgcacagt tcacttgtac cattctctac cttagggaaa caattctgct
     2341 agactaggct ttctcagctt attttcttcc aactaaagct ttccctccgt aaagctgaat
     2401 catattttac ctaccaagat atttattgat gtactctgac tacagatcag gacgaagcca
     2461 ataaggaaac atgtatctat aaagaccttc aaagataata cctgtccaat gccagtaaca
     2521 ttaaagctca actgttaggt aagtt
//
