LOCUS       NM_001410326            5099 bp    mRNA    linear   ROD 13-JUN-2024
DEFINITION  Mus musculus DExH-box helicase 57 (Dhx57), transcript variant 3,
            mRNA.
ACCESSION   NM_001410326 XM_006523447
VERSION     NM_001410326.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5099)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC132910.8.
            
            On Aug 4, 2022 this sequence version replaced XM_006523447.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR9219380.33369.1,
                                           SRR14995047.614330.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164139 [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-450               AC132910.8         48610-49059
            451-683             AC132910.8         57358-57590
            684-842             AC132910.8         60405-60563
            843-1028            AC132910.8         62751-62936
            1029-1867           AC132910.8         63184-64022
            1868-2046           AC132910.8         65676-65854
            2047-2168           AC132910.8         68298-68419
            2169-2364           AC132910.8         69839-70034
            2365-2489           AC132910.8         71147-71271
            2490-2623           AC132910.8         73577-73710
            2624-2678           AC132910.8         74784-74838
            2679-2887           AC132910.8         78356-78564
            2888-3004           AC132910.8         80596-80712
            3005-3101           AC132910.8         83138-83234
            3102-3275           AC132910.8         84348-84521
            3276-3476           AC132910.8         85499-85699
            3477-3753           AC132910.8         87278-87554
            3754-3849           AC132910.8         88671-88766
            3850-3933           AC132910.8         88850-88933
            3934-4068           AC132910.8         90381-90515
            4069-4143           AC132910.8         91603-91677
            4144-4278           AC132910.8         92977-93111
            4279-4479           AC132910.8         96634-96834
            4480-5099           AC132910.8         99856-100475
FEATURES             Location/Qualifiers
     source          1..5099
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 50.63 cM"
     gene            1..5099
                     /gene="Dhx57"
                     /note="DExH-box helicase 57"
                     /db_xref="GeneID:106794"
                     /db_xref="MGI:MGI:2147067"
     exon            1..450
                     /gene="Dhx57"
                     /inference="alignment:Splign:2.1.0"
     exon            451..683
                     /gene="Dhx57"
                     /inference="alignment:Splign:2.1.0"
     CDS             457..4623
                     /gene="Dhx57"
                     /EC_number="3.6.4.13"
                     /note="isoform 1 is encoded by transcript variant 3; DEAH
                     (Asp-Glu-Ala-Asp/His) box polypeptide 57 homolog; putative
                     ATP-dependent RNA helicase DHX57; DEAH box protein 57"
                     /codon_start=1
                     /product="putative ATP-dependent RNA helicase DHX57
                     isoform 1"
                     /protein_id="NP_001397255.1"
                     /db_xref="GeneID:106794"
                     /db_xref="MGI:MGI:2147067"
                     /translation="MSSSVRRKGKPGKGDGKGSSRGGRGGKGHMNKSHGGGGGGGGSC
                     GGGGGGSRKASNRIWDDGDDFCVFTEPKRPSRPCDSNKSKGETRPKWKPKAKVPLQTL
                     HMTSENQEKVKALLRDLQEQGADAGSERGTSGEEEDSEPQCGEEQGWPAGQEPIFLPD
                     CSPWEYIGPEEVEPPVPECAVSPLAVQKLSRYGFHTEHCQLALRICDGDLGAALEHLL
                     RQCFSETFGERMALSEAAVYVSLNECVEQRQEETLALKSICGEKFIERIQNRVWTIGL
                     ELDYLTNKFCKSKQKESSKNVRDTSPETCKFYLKGNCKFGSKCKFKHEVPPHQMIGRA
                     ERNVNDPHLDADDDTTFMYELQIRFSKDHKYPYQAPLVAFYSTNENLPLACRLHISEF
                     LYGKALEFAKTSEPVVYSLITLLEEESEIVKLLTHTQHKYSVPPVNVPPVPSETRISK
                     PAYRKPVVPSNTFLSNQMLEGERLSELEEDADEDEGPASIIVENESYVNLKKRSYKRY
                     DRPAKSLFAENSKICRQFQMKQASRQFHAILQERQLLPAWEERETILKLLSKHQVVVI
                     SGMTGCGKTTQIPQFILDNSLNGPPERVANIICTQPRRISAISVAERVAKERAERVGL
                     TVGYQIRLESVKSSATRLLYCTTGVLLRRLEGDATLQGVTHIIVDEVHERTEESDFLL
                     LVLKDIVMQRATLQVILMSATLDAGLFSKYFSYCPVITIPGRAFPVDQFFLEDALAVT
                     RYVLQDGSPYMRSMKQIAKEKLKARHNRTAQEEVEEDLRLSLHLQDEEESVKDTIPDQ
                     QLDFKQLLIRYKGVSKSVIKTMSVMDFEKVNLELIEALLEWIVDGKHAYPPGAVLVFL
                     PGLAEIKMLYEQLQSNSLFNNRRSHRCVIHPLHSSLSSEEQQAVFVKPPMGVTKIIIS
                     TNIAETSITIDDVVYVIDSGKMKEKRYDAGKGMESLEDTFVSQANALQRKGRAGRVAS
                     GVCFHLFTSHHYNHQLLKQQLPEIQRVPLEQLCLRIKILEMFSTHNLQSVFSRLIEPP
                     HIDSLRASKVRLRDLGALTPDEKLTPLGYHLASLPVDVRIGKLMLLGSIFRCLDPALT
                     IAASLAFKSPFVSPWDKKEEANQKKLEFAFANSDYLALLCAYKGWQLSTKESARASYN
                     YCRQNFLSGRTLQEMASLKRQFTELLSDIGFVKEGLRAKEIEKRAQGGDGVLDATGEE
                     ANTNAENPKLISAVLCAALYPNVVQVKTPEGKFQKTSSGVVRLQPKSAELKFVTKNDG
                     YVHIHPSSVNYQVRHFDSPYLLYHEKIKTSRVFIRDCSMVSVYPLVLFGGGQVNVQLQ
                     RGAFVVSLDDGWIRFVAASHQVAELVKELRCELDQLLQDKIKNPSMDLCSCPRGSRII
                     SMIVKLITTQ"
     exon            684..842
                     /gene="Dhx57"
                     /inference="alignment:Splign:2.1.0"
     exon            843..1028
                     /gene="Dhx57"
                     /inference="alignment:Splign:2.1.0"
     exon            1029..1867
                     /gene="Dhx57"
                     /inference="alignment:Splign:2.1.0"
     exon            1868..2046
                     /gene="Dhx57"
                     /inference="alignment:Splign:2.1.0"
     exon            2047..2168
                     /gene="Dhx57"
                     /inference="alignment:Splign:2.1.0"
     exon            2169..2364
                     /gene="Dhx57"
                     /inference="alignment:Splign:2.1.0"
     exon            2365..2489
                     /gene="Dhx57"
                     /inference="alignment:Splign:2.1.0"
     exon            2490..2623
                     /gene="Dhx57"
                     /inference="alignment:Splign:2.1.0"
     exon            2624..2678
                     /gene="Dhx57"
                     /inference="alignment:Splign:2.1.0"
     exon            2679..2887
                     /gene="Dhx57"
                     /inference="alignment:Splign:2.1.0"
     exon            2888..3004
                     /gene="Dhx57"
                     /inference="alignment:Splign:2.1.0"
     exon            3005..3101
                     /gene="Dhx57"
                     /inference="alignment:Splign:2.1.0"
     exon            3102..3275
                     /gene="Dhx57"
                     /inference="alignment:Splign:2.1.0"
     exon            3276..3476
                     /gene="Dhx57"
                     /inference="alignment:Splign:2.1.0"
     exon            3477..3753
                     /gene="Dhx57"
                     /inference="alignment:Splign:2.1.0"
     exon            3754..3849
                     /gene="Dhx57"
                     /inference="alignment:Splign:2.1.0"
     exon            3850..3933
                     /gene="Dhx57"
                     /inference="alignment:Splign:2.1.0"
     exon            3934..4068
                     /gene="Dhx57"
                     /inference="alignment:Splign:2.1.0"
     exon            4069..4143
                     /gene="Dhx57"
                     /inference="alignment:Splign:2.1.0"
     exon            4144..4278
                     /gene="Dhx57"
                     /inference="alignment:Splign:2.1.0"
     exon            4279..4479
                     /gene="Dhx57"
                     /inference="alignment:Splign:2.1.0"
     exon            4480..5099
                     /gene="Dhx57"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5082..5087
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Dhx57"
                     /note="hexamer: AATAAA"
     polyA_site      5099
                     /gene="Dhx57"
                     /note="major polyA site"
ORIGIN      
        1 agaagacacc tgggcggggc ggctgctgcg ggtgaggtcc aagagggaag ctgaacccag
       61 cccggacccc gaccctgggt gccgcctcct gagctccgca gccagcaacg ctacgagcca
      121 ggtacggcct gacgtggcat gtgcggggcc gcgcgggttc ggggttgcca ggcccgcctg
      181 ccgcctcccc tctctagtga tcacatccga ggaccatgca gcccctatgg tcctgcctgt
      241 cagcccaggg gcagtgaacc tggacctgca gaatcctggg gaaccccggg atctgcagtc
      301 gaggtcgtcc acacccacgg ctccgagcaa ggttgaaaag gaggggcgcc agccccattt
      361 cctgtctgtg gctcggtggc gacccgaggg gctgtttggg gaaagggttg gagaagatgg
      421 atgttgaaga aaggaacctt gcatgactag gtgaaaatga gttcttcagt aagaagaaaa
      481 ggcaagccag gcaaagggga tggaaaggga tcgtctagag gcggaagagg aggcaaaggt
      541 cacatgaata aatctcatgg gggtggaggt ggcggcggcg gtagctgcgg cggcggaggc
      601 ggcggcagta gaaaggcctc aaatagaatt tgggatgatg gcgatgactt ttgtgtcttc
      661 actgagccca agcgcccgtc caggccctgc gacagtaaca aaagcaaagg agagacacgg
      721 cctaagtgga agcccaaagc caaagtgccc cttcagacgc tgcacatgac atcagagaat
      781 caggagaagg tgaaagccct tctgagggat ctgcaggaac agggtgcgga cgcgggatcc
      841 gaaagaggca cctctgggga ggaggaagac agcgagcccc agtgtggcga ggagcagggc
      901 tggccagctg gacaagagcc tatctttctt cctgactgca gtccttggga atatataggc
      961 ccagaagaag tggagcctcc tgtgccagaa tgtgcagtct cacccttggc agtgcagaaa
     1021 ctttccaggt acggcttcca cactgagcac tgtcagctgg ccctgaggat ctgtgatgga
     1081 gacttagggg cggcactaga gcatcttctc cgccagtgtt tctcagagac gtttggagag
     1141 aggatggcgc tctctgaggc agctgtttat gtgagcttga atgagtgtgt ggagcagaga
     1201 caggaagaga cgcttgctct caagtccatc tgcggagaaa aattcataga aagaattcag
     1261 aacagagtct ggaccattgg attggaactg gattatttga caaacaaatt ctgcaagtct
     1321 aagcaaaagg aaagtagcaa aaatgtacgg gacacttcgc ctgaaacctg taaattttac
     1381 ctcaaaggaa attgtaaatt tggatcaaaa tgcaaattca aacatgaagt gcccccacat
     1441 caaatgattg ggagagcaga aagaaacgta aatgaccctc accttgacgc tgatgacgac
     1501 acaaccttta tgtatgagct tcagattcgc ttttctaaag accacaaata cccctaccaa
     1561 gctcccctgg tggcatttta ttccaccaat gagaacctac ctctggcttg tcgtttacat
     1621 atttctgagt tcctttatgg caaggccttg gaatttgcaa aaacttcaga acctgttgtc
     1681 tattctctga tcaccctttt agaggaagag tcagagattg tcaagttact aacacacact
     1741 caacataagt atagcgttcc tcctgtgaac gtccctccag taccttccga gaccagaata
     1801 agtaaacctg cctaccgcaa accagtggtc ccaagtaaca ctttcctttc taatcaaatg
     1861 ctagaagggg aaagattgtc agaactcgag gaggatgccg atgaggatga aggacctgca
     1921 tcaattatcg tggagaatga aagctatgtg aacctgaaga agaggagtta caaaagatac
     1981 gacaggccgg caaagtcctt atttgctgag aacagtaaga tctgcaggca gtttcagatg
     2041 aaacaggctt ccagacagtt ccacgcaatt ctgcaagaaa gacagttact gcctgcttgg
     2101 gaagagagag agaccattct gaaactgctg agcaagcacc aagtggttgt cataagtggt
     2161 atgactggat gtgggaaaac cacacagatt ccacagttta tcctggataa ttctctgaat
     2221 gggccacccg agagggtggc caacatcatc tgtacccaac cccgacggat ctctgcaatc
     2281 tctgttgctg aacgggttgc taaagaaaga gcagaacggg tgggtctgac tgtgggatac
     2341 cagattcggc tggaaagtgt caagtcctca gccaccagac tgttatactg caccacagga
     2401 gtgctgctga gaaggctaga gggagatgcg actttgcagg gagtcaccca catcattgtt
     2461 gatgaagttc atgagaggac agaagaaagt gacttcttac tgctagtttt gaaggacatt
     2521 gtgatgcaga gagcgaccct ccaggtcatt ctcatgagtg caactctgga cgctgggctg
     2581 ttctccaagt atttcagcta ctgcccagtc atcaccatcc caggccgtgc atttcctgtt
     2641 gatcagtttt tcctggagga tgcgctggct gtgacgaggt atgtgttaca ggacgggagc
     2701 ccatatatgc gttccatgaa acagattgcg aaggaaaagc ttaaagccag gcacaacaga
     2761 actgcacagg aggaggtaga ggaagacctg aggctgtccc tccatctcca ggacgaggag
     2821 gagtctgtca aagatacaat acctgatcaa cagttggatt tcaagcagct cttgatccgt
     2881 tataaagggg tgagcaagtc agtcatcaag acaatgtctg tgatggattt tgaaaaggtc
     2941 aaccttgaac taatagaggc cttgttagag tggattgtag acggcaagca cgcctaccct
     3001 ccaggcgctg tccttgtgtt cttaccaggg ctggcagaaa tcaagatgct ttatgagcag
     3061 ctacagtcta actctctttt caacaacaga cgcagtcacc gatgtgtaat tcacccgctg
     3121 cactcatcat tatccagcga agagcagcag gcggtgtttg tgaaacctcc aatgggtgta
     3181 actaagatta tcatttccac caacattgct gagacgtcta taaccattga tgatgttgtg
     3241 tatgtcatcg attctgggaa gatgaaagaa aagagatacg acgcaggcaa aggaatggaa
     3301 agtctagagg acacgttcgt gtctcaggcc aacgctctgc agaggaaagg ccgagctggc
     3361 cgagtcgcat caggggtctg cttccacttg ttcacgagcc accactacaa ccaccagctt
     3421 ctgaagcagc agctcccaga aatccagcga gtgcccctgg agcagctgtg cctcagaatt
     3481 aaaattttag aaatgtttag tactcataat ctccagtccg tgttctctcg gctcattgaa
     3541 cctccacata ttgattctct tcgtgcctca aaagtacggt tgcgagactt gggagccttg
     3601 actccagatg aaaaactgac cccgctgggt tatcacttgg cctctctgcc cgtggacgtg
     3661 aggataggca agctgatgct cttaggttct atcttccgct gtttggaccc tgctctcacc
     3721 attgctgcca gcttggcttt caagtcccct tttgtgtctc cctgggataa gaaagaagaa
     3781 gctaatcaga aaaagctgga gtttgcattt gcaaacagcg attacctggc ccttctatgt
     3841 gcatataagg gttggcagct gagtacaaaa gaaagcgcac gagcaagcta taattactgc
     3901 agacagaatt tcctgtctgg gagaaccctg caggaaatgg ccagcctcaa acgacaattc
     3961 actgaactgc tgtccgacat agggtttgtg aaagaaggac tccgagcaaa agaaattgaa
     4021 aaacgagccc agggaggaga tggtgtcctg gatgccacag gagaggaggc taacacaaat
     4081 gctgagaacc ccaagctgat atcagcagtg ctgtgtgccg ctctgtatcc aaacgtagta
     4141 caggtcaaga ccccagaggg aaagttccag aagaccagtt ctggagtggt cagactgcag
     4201 ccaaagtcag ctgagctgaa gttcgttacc aagaatgacg gatatgtcca cattcaccct
     4261 tcctcagtga actatcaggt cagacacttc gacagcccct acctgttgta ccatgagaaa
     4321 atcaaaacta gccgggtgtt catccgagac tgcagcatgg tgtctgtgta tcccctggtc
     4381 ttgtttggag ggggccaagt gaacgtgcag cttcaaagag gggcgttcgt cgtctccttg
     4441 gatgacggct ggatccggtt tgtggccgcc tcccaccagg tggccgagct ggtgaaggaa
     4501 ctccgctgcg aacttgacca gctcctccag gataagatta aaaaccccag catggacctg
     4561 tgcagctgtc cgaggggctc tcggattatc agcatgatcg tgaagctcat caccacacag
     4621 tgacgactgg gcctggccgc ctgctctgca cctctgctcc ccggcaaggc acaggagcgc
     4681 gcctacctcc cacggaagac tggcttgggg ctgcccctgg ggtgcagagc cagggcccca
     4741 caacccaaga gacagtctcc acactggtgt ttctgaaaac gtggggacac tcccagcaca
     4801 atttggagcg tccgtggtag gacagcctaa aacccagctt gtctttctgt gactgtacca
     4861 aactgaatgc aattcacctc ataacttaaa actgaatgtt taatacaatt ctgtcttaat
     4921 ccatgtatcc tttccctcct attttttatt atgcattgtc tatacttaat tggtgattct
     4981 tttctcttgt tttttactgg gcatgaggag aaatgtttgg tttggctttc cccatcataa
     5041 taaaggaaat gaaaggaaga aagaaatcat gtgagtaaga aaataaaact ttcatttta
//
