LOCUS       NM_027883               3801 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus DExH-box helicase 34 (Dhx34), mRNA.
ACCESSION   NM_027883 XM_914426
VERSION     NM_027883.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3801)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3801)
  AUTHORS   Hoffman,B.G., Zavaglia,B., Witzsche,J., Ruiz de Algara,T.,
            Beach,M., Hoodless,P.A., Jones,S.J., Marra,M.A. and Helgason,C.D.
  TITLE     Identification of transcripts with enriched expression in the
            developing and adult pancreas
  JOURNAL   Genome Biol 9 (6), R99 (2008)
   PUBMED   18554416
REFERENCE   3  (bases 1 to 3801)
  AUTHORS   Garcia-Frigola,C., Burgaya,F., Calbet,M., Lopez-Domenech,G., de
            Lecea,L. and Soriano,E.
  TITLE     A collection of cDNAs enriched in upper cortical layers of the
            embryonic mouse brain
  JOURNAL   Brain Res Mol Brain Res 122 (2), 133-150 (2004)
   PUBMED   15010206
REFERENCE   4  (bases 1 to 3801)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Koseki,H., Hiraoka,S.,
            Saga,Y., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: III. the complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (4), 167-180 (2003)
   PUBMED   14621295
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK004733.1.
            
            On Jun 3, 2007 this sequence version replaced NM_027883.2.
            
            Transcript Variant: This variant (3) differs in the 5' UTR compared
            to variant 1. All three variants encode the same protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK004733.1, AK129062.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-3801              AK004733.1         2-3802
FEATURES             Location/Qualifiers
     source          1..3801
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 8.76 cM"
     gene            1..3801
                     /gene="Dhx34"
                     /gene_synonym="1200013B07Rik; 1810012L18Rik; Ddx34;
                     mKIAA0134"
                     /note="DExH-box helicase 34"
                     /db_xref="GeneID:71723"
                     /db_xref="MGI:MGI:1918973"
     exon            1..35
                     /gene="Dhx34"
                     /gene_synonym="1200013B07Rik; 1810012L18Rik; Ddx34;
                     mKIAA0134"
                     /inference="alignment:Splign:2.1.0"
     exon            36..998
                     /gene="Dhx34"
                     /gene_synonym="1200013B07Rik; 1810012L18Rik; Ddx34;
                     mKIAA0134"
                     /inference="alignment:Splign:2.1.0"
     CDS             288..3725
                     /gene="Dhx34"
                     /gene_synonym="1200013B07Rik; 1810012L18Rik; Ddx34;
                     mKIAA0134"
                     /EC_number="3.6.4.13"
                     /note="DEAH box protein 34; DEAH (Asp-Glu-Ala-His) box
                     polypeptide 34"
                     /codon_start=1
                     /product="probable ATP-dependent RNA helicase DHX34"
                     /protein_id="NP_082159.3"
                     /db_xref="CCDS:CCDS39783.1"
                     /db_xref="GeneID:71723"
                     /db_xref="MGI:MGI:1918973"
                     /translation="MPPPRTREGRGHRDRDHHRAPREEEAPEKWDWNCPETRCLLEDV
                     FFRDEDYIRRGSEECQKFWAFFERLQRFQHLKTSQKKEKDPGMPKHGIAALADLPLTY
                     DPRYRINLSILSPDTRGRHGPGRGLPPERVSEFRRALLHYLDFQQKQAFGRLVKLQRE
                     RAALPIAQYGNRILQTLKEHQVVVVAGDTGCGKSTQVPQYLLAAGFSHVACTQPRRIA
                     CISLAKRVGFESLSQYGSQVGYQIRFESTRSAATKIVFLTVGLLLRQIQREPSLPQYQ
                     VLIVDEVHERHLHNDFLLGVLQRLLPQRPDLKVILMSATINISLFSSYFSHAPVVQVP
                     GRLFPITVVYQPQEADQTASKSEKLDPRPFLRVLEAIDNKYPPEERGDLLVFLSGMAE
                     ITTVLDAAQAYASLTQRWVVLPLHSALSVSDQDKVFDVAPAGVRKCILSTNIAETSVT
                     IDGIRFVVDSGKVKEMSYDPQAKLQRLQEFWISQASAEQRKGRAGRTGPGVCYRLYAE
                     SDYDAFAPYPVPEIRRVALDALVLQMKSMSVGDPRTFPFIEPPPPASVETAILYLQEQ
                     GALDSSEALTPIGSLLAQLPVDVVIGKMLILGSMFSLAEPVLTIAAALSVQSPFTRSA
                     QSNLDCATARRPLESDQGDPFTLFNVFNAWVQVKSERSGNSRKWCRRRGVEEHRLYEM
                     ANLRRQFKELLEDHGLLSGAQVVAPGDSYSRLQQRRERRALHQLKRQHEEGGGRRRKV
                     LRLQEDGCSSDEEDREGSTSQRADSVDIQDVKFKLRHNLEQLQAAASSAQDLTRDQLA
                     LLKLVLGRGLYPQLAVPDAFNSGRKDSDQIFHTQAKQGTVLHPTCVFANSPEVLHTQG
                     QEASGQEGSQDGRDQMSCKHQLLAFVSLLETNKPYLVNCVRIPALQSLLLFSRSIDTN
                     GDCSRLVADGWLELQLADSESAVRLLATSLRLRVHWESALDRQLARQAQRRKLEQEED
                     MGSPAVSPQEVAALSRELLQFMVAKVPYRLRRLTGLEAQNLYVGPQTITTAPSLPGLF
                     GNSTLSPHPTKGGYAVSDYLTYNCLTSDTDLYSDCLRSFWTCPHCGLHMPFTPLERIA
                     HENTCPEAPGDDPGSEEAAPAPPQKTSALQRPYHCQVCGQDFLFTPTEVLRHRRQHV"
     exon            999..1310
                     /gene="Dhx34"
                     /gene_synonym="1200013B07Rik; 1810012L18Rik; Ddx34;
                     mKIAA0134"
                     /inference="alignment:Splign:2.1.0"
     exon            1311..1565
                     /gene="Dhx34"
                     /gene_synonym="1200013B07Rik; 1810012L18Rik; Ddx34;
                     mKIAA0134"
                     /inference="alignment:Splign:2.1.0"
     exon            1566..1668
                     /gene="Dhx34"
                     /gene_synonym="1200013B07Rik; 1810012L18Rik; Ddx34;
                     mKIAA0134"
                     /inference="alignment:Splign:2.1.0"
     exon            1669..1886
                     /gene="Dhx34"
                     /gene_synonym="1200013B07Rik; 1810012L18Rik; Ddx34;
                     mKIAA0134"
                     /inference="alignment:Splign:2.1.0"
     exon            1887..2061
                     /gene="Dhx34"
                     /gene_synonym="1200013B07Rik; 1810012L18Rik; Ddx34;
                     mKIAA0134"
                     /inference="alignment:Splign:2.1.0"
     exon            2062..2255
                     /gene="Dhx34"
                     /gene_synonym="1200013B07Rik; 1810012L18Rik; Ddx34;
                     mKIAA0134"
                     /inference="alignment:Splign:2.1.0"
     exon            2256..2357
                     /gene="Dhx34"
                     /gene_synonym="1200013B07Rik; 1810012L18Rik; Ddx34;
                     mKIAA0134"
                     /inference="alignment:Splign:2.1.0"
     exon            2358..2594
                     /gene="Dhx34"
                     /gene_synonym="1200013B07Rik; 1810012L18Rik; Ddx34;
                     mKIAA0134"
                     /inference="alignment:Splign:2.1.0"
     exon            2595..2768
                     /gene="Dhx34"
                     /gene_synonym="1200013B07Rik; 1810012L18Rik; Ddx34;
                     mKIAA0134"
                     /inference="alignment:Splign:2.1.0"
     exon            2769..2886
                     /gene="Dhx34"
                     /gene_synonym="1200013B07Rik; 1810012L18Rik; Ddx34;
                     mKIAA0134"
                     /inference="alignment:Splign:2.1.0"
     exon            2887..2993
                     /gene="Dhx34"
                     /gene_synonym="1200013B07Rik; 1810012L18Rik; Ddx34;
                     mKIAA0134"
                     /inference="alignment:Splign:2.1.0"
     exon            2994..3278
                     /gene="Dhx34"
                     /gene_synonym="1200013B07Rik; 1810012L18Rik; Ddx34;
                     mKIAA0134"
                     /inference="alignment:Splign:2.1.0"
     exon            3279..3455
                     /gene="Dhx34"
                     /gene_synonym="1200013B07Rik; 1810012L18Rik; Ddx34;
                     mKIAA0134"
                     /inference="alignment:Splign:2.1.0"
     exon            3456..3591
                     /gene="Dhx34"
                     /gene_synonym="1200013B07Rik; 1810012L18Rik; Ddx34;
                     mKIAA0134"
                     /inference="alignment:Splign:2.1.0"
     exon            3592..3801
                     /gene="Dhx34"
                     /gene_synonym="1200013B07Rik; 1810012L18Rik; Ddx34;
                     mKIAA0134"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3778..3783
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Dhx34"
                     /gene_synonym="1200013B07Rik; 1810012L18Rik; Ddx34;
                     mKIAA0134"
                     /note="putative"
     polyA_site      3801
                     /gene="Dhx34"
                     /gene_synonym="1200013B07Rik; 1810012L18Rik; Ddx34;
                     mKIAA0134"
                     /note="putative"
ORIGIN      
        1 ggaccggaag ttgaggcgtc cgtgctattt cggagaacct ggaagtccag aatggaccct
       61 tgtcccttcc agagaccact gcaggagtca tgaagcgctt tgtgcagctc cacctaccca
      121 ccaggcccct ggctacccac cctgccgtcc acagagcctc tgtacatgga aaggggaggt
      181 gactctttga agagaaagca gttcctgggg tcgggagtta ggtgagaata cttagtctaa
      241 gcgatcagaa cggagactgt ttctgtgaca gcagtttgat aggaaccatg cctcctccca
      301 ggacaaggga ggggaggggt caccgagacc gagaccacca tcgagctccc agggaggaag
      361 aggccccgga gaaatgggac tggaattgtc cagagactcg ttgtctcttg gaagatgtat
      421 tcttccgcga tgaggattat atccgtcgtg gttcagagga gtgtcagaag ttctgggctt
      481 tctttgaacg cctgcagaga ttccagcacc tcaagacctc ccagaagaag gagaaggacc
      541 ctggcatgcc caaacatggc atcgctgctt tagctgacct acctctcact tacgacccac
      601 gctaccgcat caacctctcc attctcagcc cagacactcg gggtcgtcat gggcccggca
      661 gggggctgcc gcccgagaga gtgtccgagt tccgccgtgc attgcttcac tacctagact
      721 tccagcagaa gcaggctttt gggaggctcg tcaaactgca gcgtgagcga gcggcacttc
      781 ccatcgccca gtatgggaac cgcatcctgc agactctcaa ggaacaccag gtggtggtgg
      841 tggccgggga cacaggctgt ggcaagtcta ctcaggtgcc ccagtacttg ctggccgccg
      901 gcttcagtca cgtggcatgc actcagcccc ggagaatcgc ctgcatctca ctggccaagc
      961 gcgttggctt cgagagcctc agtcagtatg gctcccaggt tggctaccag atccgctttg
     1021 aaagcactcg gtcggcagcc accaagatcg tgttcctgac ggtggggctg ctcctacgcc
     1081 agatccagcg tgagcccagc ctgccccagt accaggtcct gatcgtggac gaggtccacg
     1141 agcgacacct gcacaatgac ttcctgctgg gtgtcctgca gcgcctgctg ccccagcggc
     1201 ctgacctcaa ggtcatcctc atgtcggcca ccatcaacat ctctctcttc tccagctact
     1261 tcagccatgc tccggtggtg caggtgcctg ggaggctctt ccccatcacg gtagtctacc
     1321 agccgcagga ggcagaccag acagcatcca agtcagagaa gctggaccca cggcccttcc
     1381 tgagggtgct ggaggccatc gacaataagt atccccccga ggagcggggg gaccttcttg
     1441 tcttcctcag tggcatggcg gagatcacca cggtgctgga cgcagcccag gcttatgcca
     1501 gcctcaccca gcgctgggtg gtgctgccgc tgcacagcgc cctctctgtg tctgaccagg
     1561 acaaggtgtt cgatgtggct ccagctggag tccggaagtg catcctgtcc accaacattg
     1621 ccgagacctc agtcacgatc gatggcatcc gcttcgtggt ggattctggg aaggtgaagg
     1681 agatgagcta cgacccacag gccaaactgc agcggctgca ggaattctgg atcagccagg
     1741 ccagtgctga gcagcgcaag ggccgagcgg gccgcacggg ccccggcgtc tgctaccgtc
     1801 tctatgccga gtctgactat gatgcctttg cgccgtaccc agtcccggaa atccgcaggg
     1861 tggccctgga tgcactggtg cttcagatga agagtatgag tgtgggggac ccacgcacct
     1921 tccccttcat cgagccccct ccacctgcca gcgtggaaac cgctatcctc tatctccaag
     1981 agcagggggc cctggacagc tcggaggccc tcacccccat cgggtccctg ctggcccagc
     2041 tgcctgtaga tgttgtaatt gggaagatgc tgatcctcgg ctccatgttc agcctggcag
     2101 agcctgtgct caccattgct gctgccctca gcgtccagtc accattcacc cgcagtgccc
     2161 agagcaacct ggactgtgcc actgcccgga gaccgctgga aagtgaccag ggtgacccct
     2221 tcacactctt caatgtcttc aatgcctggg tgcaggtgaa gtctgagcgg agcggaaact
     2281 ctcgaaagtg gtgccgccgc cggggtgtgg aggagcaccg gctgtatgag atggccaacc
     2341 tgcggcgcca gttcaaggag ctgttggagg atcatggatt gctgagtggg gcccaggtag
     2401 tggccccagg ggacagctac agtcggctgc agcagcgccg agagcgcagg gccctgcacc
     2461 agctgaagcg acagcatgag gagggtgggg gacgcaggcg caaggtgctg aggctgcagg
     2521 aggatggctg ctccagcgat gaagaggacc gagagggctc tacctcccag agggctgaca
     2581 gcgttgacat ccaggatgtg aaattcaagc ttcggcacaa cctggagcag ctgcaggcag
     2641 ctgccagctc agcccaggac ctgacccgag accaactggc cctgctcaag ctggtgctcg
     2701 ggcgggggct gtacccacag ctggctgtgc ccgatgcgtt caacagtggc cgcaaggact
     2761 cagaccagat tttccacacg caggccaagc agggcaccgt gctgcacccc acctgtgtct
     2821 ttgccaacag ccctgaggta ttacacacac aggggcagga ggcctcaggc caagaaggga
     2881 gccaagatgg cagggaccaa atgagctgca agcatcagct gctggccttc gtctccctac
     2941 tggagaccaa caagccatac ctggtgaact gcgtcagaat cccggccctc cagtccctcc
     3001 tgctgttcag ccgctccatt gacaccaacg gtgactgctc ccgcctggtg gctgacggtt
     3061 ggctagagct gcagctcgca gatagcgaga gtgccgtccg gctcctggca acatccctgc
     3121 ggctccgtgt ccactgggaa agtgccctgg accggcagct ggcccgccag gcccagcgac
     3181 ggaagctaga gcaggaggaa gacatggggt ctccagcagt cagcccccag gaggtggctg
     3241 ctctgagcag ggagctgctg cagttcatgg tggccaaggt tccctaccgc ctccgaaggc
     3301 tcactggtct agaagcccag aacctctacg tgggacccca gaccatcacg accgccccta
     3361 gtctgcccgg cctctttgga aattctaccc tgtctccaca ccccaccaag gggggctacg
     3421 ctgtctctga ttatctcacc tacaactgcc tcacgagtga cactgacctg tacagtgact
     3481 gtctgcgttc cttctggacc tgcccacact gtggcctgca catgcccttc acacccttgg
     3541 agcgcattgc tcatgagaac acctgccctg aggcgccagg cgatgatcca gggtctgagg
     3601 aggctgctcc tgcaccacca cagaagacat cagccctgca gaggccctac cactgccagg
     3661 tgtgcgggca ggacttcctc tttaccccaa ctgaggtact aagacatcga aggcagcatg
     3721 tctgagccag cactgctcct ggagcgccca agtgggggac agcagtgtgt ccatgcaaat
     3781 aaagtcaggc tttgcttcag g
//
