LOCUS       NM_001252682            4228 bp    mRNA    linear   ROD 10-FEB-2025
DEFINITION  Mus musculus DExH-box helicase 30 (Dhx30), transcript variant 1,
            mRNA.
ACCESSION   NM_001252682
VERSION     NM_001252682.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4228)
  AUTHORS   Liu,Y., Liu,F., Li,Y., Li,Y., Feng,Y., Zhao,J., Zhou,C., Li,C.,
            Shen,J. and Zhang,Y.
  TITLE     LncRNA Anxa10-203 enhances Mc1r mRNA stability to promote
            neuropathic pain by recruiting DHX30 in the trigeminal ganglion
  JOURNAL   J Headache Pain 25 (1), 28 (2024)
   PUBMED   38433184
  REMARK    GeneRIF: LncRNA Anxa10-203 enhances Mc1r mRNA stability to promote
            neuropathic pain by recruiting DHX30 in the trigeminal ganglion.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4228)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 4228)
  AUTHORS   Nakano,Y., Wiechert,S. and Banfi,B.
  TITLE     Overlapping Activities of Two Neuronal Splicing Factors Switch the
            GABA Effect from Excitatory to Inhibitory by Regulating REST
  JOURNAL   Cell Rep 27 (3), 860-871 (2019)
   PUBMED   30995482
REFERENCE   4  (bases 1 to 4228)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24643.. PMID: 29144450]
REFERENCE   5  (bases 1 to 4228)
  AUTHORS   Zheng,H.J., Tsukahara,M., Liu,E., Ye,L., Xiong,H., Noguchi,S.,
            Suzuki,K. and Ji,Z.S.
  TITLE     The novel helicase helG (DHX30) is expressed during gastrulation in
            mice and has a structure similar to a human DExH box helicase
  JOURNAL   Stem Cells Dev 24 (3), 372-383 (2015)
   PUBMED   25219788
  REMARK    GeneRIF: An improved gene trap method 'trapped' a helG gene
            expressed in mouse ES cells. The helG product shared a high level
            of homology with the DExH RNA helicase family. It is required for
            differentiation during embryogenesis.
REFERENCE   6  (bases 1 to 4228)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   7  (bases 1 to 4228)
  AUTHORS   Watanabe,A., Tatematsu,M., Saeki,K., Shibata,S., Shime,H.,
            Yoshimura,A., Obuse,C., Seya,T. and Matsumoto,M.
  TITLE     Raftlin is involved in the nucleocapture complex to induce
            poly(I:C)-mediated TLR3 activation
  JOURNAL   J Biol Chem 286 (12), 10702-10711 (2011)
   PUBMED   21266579
REFERENCE   8  (bases 1 to 4228)
  AUTHORS   McKee,A.E., Minet,E., Stern,C., Riahi,S., Stiles,C.D. and
            Silver,P.A.
  TITLE     A genome-wide in situ hybridization map of RNA-binding proteins
            reveals anatomically restricted expression in the developing mouse
            brain
  JOURNAL   BMC Dev Biol 5, 14 (2005)
   PUBMED   16033648
  REMARK    Publication Status: Online-Only
REFERENCE   9  (bases 1 to 4228)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Aizawa,H., Yuasa,S.,
            Nakajima,D., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: II. The complete nucleotide sequences of 400 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (1), 35-48 (2003)
   PUBMED   12693553
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC159372.1, AK159601.1, CF724787.1 and BY540912.1.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the shortest isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK159601.1, AK153969.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164138, SAMN01164139
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            RefSeq Select criteria             :: based on conservation,
                                                  expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-202               AC159372.1         140557-140758
            203-1671            AK159601.1         1-1469
            1672-1672           CF724787.1         38-38
            1673-4224           AK159601.1         1471-4022
            4225-4228           BY540912.1         381-384
FEATURES             Location/Qualifiers
     source          1..4228
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 59.86 cM"
     gene            1..4228
                     /gene="Dhx30"
                     /gene_synonym="2810477H02Rik; C130058C04Rik; Ddx30; HELG;
                     Ret-CoR"
                     /note="DExH-box helicase 30"
                     /db_xref="GeneID:72831"
                     /db_xref="MGI:MGI:1920081"
     exon            1..259
                     /gene="Dhx30"
                     /gene_synonym="2810477H02Rik; C130058C04Rik; Ddx30; HELG;
                     Ret-CoR"
                     /inference="alignment:Splign:2.1.0"
     exon            260..351
                     /gene="Dhx30"
                     /gene_synonym="2810477H02Rik; C130058C04Rik; Ddx30; HELG;
                     Ret-CoR"
                     /inference="alignment:Splign:2.1.0"
     exon            352..477
                     /gene="Dhx30"
                     /gene_synonym="2810477H02Rik; C130058C04Rik; Ddx30; HELG;
                     Ret-CoR"
                     /inference="alignment:Splign:2.1.0"
     exon            478..597
                     /gene="Dhx30"
                     /gene_synonym="2810477H02Rik; C130058C04Rik; Ddx30; HELG;
                     Ret-CoR"
                     /inference="alignment:Splign:2.1.0"
     CDS             570..4154
                     /gene="Dhx30"
                     /gene_synonym="2810477H02Rik; C130058C04Rik; Ddx30; HELG;
                     Ret-CoR"
                     /EC_number="3.6.4.13"
                     /note="isoform 1 is encoded by transcript variant 1;
                     putative ATP-dependent RNA helicase DHX30; DEAH
                     (Asp-Glu-Ala-His) box polypeptide 30; DEAH box protein 30"
                     /codon_start=1
                     /product="ATP-dependent RNA helicase DHX30 isoform 1"
                     /protein_id="NP_001239611.1"
                     /db_xref="CCDS:CCDS57706.1"
                     /db_xref="GeneID:72831"
                     /db_xref="MGI:MGI:1920081"
                     /translation="MFSLDSFRKDRTQHRQRQCKLPPPRLPPMCVNPAPGGTITRASR
                     DLLKEFPQPKNLLNSVIGRALGISHAKDKLVYVHTNGPKKKKVTLHIKWPKSVEVEGY
                     GSKKIDAERQAAAAACQLFKGWGLLGPRNELFDAAKYRVLADRFGSPADSWWRPEPTM
                     PPTSWRQLNPENIRPGGPAGLSRSLGREEEEDEEEELEEGTIDVTEFLSMTQQDSHNP
                     LRDSRGGSFEMTDDDSAIRALTQFPLPKNLLAKVIQIATSSSTAKNLMQFHTVGTKTK
                     LATLTLLWPCPMTFVAKGRRKAEAENKAAALACKKLKSLGLVDRNNEPLTHAMYNLAS
                     LRELGETQRRPCTIQVPEPILRKIEAFLSHYPVDSSWISPELRLQSDDILPLGKDSGP
                     LSDPITGKPYMPLSEAEEVRLSQSLLELWRRRGPIWQEAPQLPVDPHRDTILSAIEQH
                     PVVVISGDTGCGKTTRIPQLLLERYVTEGRGARCNVIITQPRRISAVSVAQRVSHELG
                     PSLRRNVGFQVRLESKPPARGGALLFCTVGILLRKLQSNPSLEGVSHVIVDEVHERDV
                     NTDFLLILLKGLQRLNPALRLVLMSATGDNERFSRYFGGCPVIKVPGFMYPVKEHYLE
                     DILAKLGKHQYPHRHRHHESEDECALDLDLVTDLVLHIDARGEPGGILCFLPGWQEIK
                     GVQQRLQEALGMHESKYLILPVHSNIPMMDQKAIFQQPPLGVRKIVLATNIAETSITV
                     NDIVHVVDSGLHKEERYDLKTKVSCLETVWVSRANVIQRRGRAGRCQSGFAYHLFPRS
                     RLEKMVPFQVPEILRTPLENLVLQAKIHMPEKTAVEFLSKAVDSPNIKAVDEAVILLQ
                     EIGVLDQREYLTTLGQRLAHISTDPRLAKAIVLAAIFRCLHPLLVVVSCLTRDPFSSS
                     LQNRAEVDKVKALLSHDSGSDHLAFVRAVAGWEEVLRWQDRTSRENYLEENLLYAPSL
                     RFIHGLIKQFSENIYEAFLVGKPSDCTLPSAQCNEYSEEEELVKGVLMAGLYPNLIQV
                     RQGKVTRQGKFKPNSVTYRTKSGNILLHKSTINREATRLRSRWLTYFMAVKSNGSVFV
                     RDSSQVHPLAVLLLTDGDVHIRDDGRRATISLSDSDLLRLEGDSRTVRLLREFRRALG
                     RMVERSLRSELAALPLSVQQEHGQLLALLAELLRGPCGSFDMRKTADD"
     exon            598..693
                     /gene="Dhx30"
                     /gene_synonym="2810477H02Rik; C130058C04Rik; Ddx30; HELG;
                     Ret-CoR"
                     /inference="alignment:Splign:2.1.0"
     exon            694..824
                     /gene="Dhx30"
                     /gene_synonym="2810477H02Rik; C130058C04Rik; Ddx30; HELG;
                     Ret-CoR"
                     /inference="alignment:Splign:2.1.0"
     exon            825..935
                     /gene="Dhx30"
                     /gene_synonym="2810477H02Rik; C130058C04Rik; Ddx30; HELG;
                     Ret-CoR"
                     /inference="alignment:Splign:2.1.0"
     exon            936..1237
                     /gene="Dhx30"
                     /gene_synonym="2810477H02Rik; C130058C04Rik; Ddx30; HELG;
                     Ret-CoR"
                     /inference="alignment:Splign:2.1.0"
     exon            1238..1358
                     /gene="Dhx30"
                     /gene_synonym="2810477H02Rik; C130058C04Rik; Ddx30; HELG;
                     Ret-CoR"
                     /inference="alignment:Splign:2.1.0"
     exon            1359..1508
                     /gene="Dhx30"
                     /gene_synonym="2810477H02Rik; C130058C04Rik; Ddx30; HELG;
                     Ret-CoR"
                     /inference="alignment:Splign:2.1.0"
     exon            1509..1661
                     /gene="Dhx30"
                     /gene_synonym="2810477H02Rik; C130058C04Rik; Ddx30; HELG;
                     Ret-CoR"
                     /inference="alignment:Splign:2.1.0"
     exon            1662..2498
                     /gene="Dhx30"
                     /gene_synonym="2810477H02Rik; C130058C04Rik; Ddx30; HELG;
                     Ret-CoR"
                     /inference="alignment:Splign:2.1.0"
     exon            2499..2574
                     /gene="Dhx30"
                     /gene_synonym="2810477H02Rik; C130058C04Rik; Ddx30; HELG;
                     Ret-CoR"
                     /inference="alignment:Splign:2.1.0"
     exon            2575..2679
                     /gene="Dhx30"
                     /gene_synonym="2810477H02Rik; C130058C04Rik; Ddx30; HELG;
                     Ret-CoR"
                     /inference="alignment:Splign:2.1.0"
     exon            2680..2855
                     /gene="Dhx30"
                     /gene_synonym="2810477H02Rik; C130058C04Rik; Ddx30; HELG;
                     Ret-CoR"
                     /inference="alignment:Splign:2.1.0"
     exon            2856..3062
                     /gene="Dhx30"
                     /gene_synonym="2810477H02Rik; C130058C04Rik; Ddx30; HELG;
                     Ret-CoR"
                     /inference="alignment:Splign:2.1.0"
     exon            3063..3144
                     /gene="Dhx30"
                     /gene_synonym="2810477H02Rik; C130058C04Rik; Ddx30; HELG;
                     Ret-CoR"
                     /inference="alignment:Splign:2.1.0"
     exon            3145..3338
                     /gene="Dhx30"
                     /gene_synonym="2810477H02Rik; C130058C04Rik; Ddx30; HELG;
                     Ret-CoR"
                     /inference="alignment:Splign:2.1.0"
     exon            3339..3498
                     /gene="Dhx30"
                     /gene_synonym="2810477H02Rik; C130058C04Rik; Ddx30; HELG;
                     Ret-CoR"
                     /inference="alignment:Splign:2.1.0"
     exon            3499..3656
                     /gene="Dhx30"
                     /gene_synonym="2810477H02Rik; C130058C04Rik; Ddx30; HELG;
                     Ret-CoR"
                     /inference="alignment:Splign:2.1.0"
     exon            3657..3760
                     /gene="Dhx30"
                     /gene_synonym="2810477H02Rik; C130058C04Rik; Ddx30; HELG;
                     Ret-CoR"
                     /inference="alignment:Splign:2.1.0"
     exon            3761..3900
                     /gene="Dhx30"
                     /gene_synonym="2810477H02Rik; C130058C04Rik; Ddx30; HELG;
                     Ret-CoR"
                     /inference="alignment:Splign:2.1.0"
     exon            3901..4228
                     /gene="Dhx30"
                     /gene_synonym="2810477H02Rik; C130058C04Rik; Ddx30; HELG;
                     Ret-CoR"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4202..4207
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Dhx30"
                     /gene_synonym="2810477H02Rik; C130058C04Rik; Ddx30; HELG;
                     Ret-CoR"
                     /note="hexamer: AATAAA"
     polyA_site      4227
                     /gene="Dhx30"
                     /gene_synonym="2810477H02Rik; C130058C04Rik; Ddx30; HELG;
                     Ret-CoR"
                     /note="major polyA site"
ORIGIN      
        1 cgcagactga ctgtctcgcg ctgtgggctg aggaacacta gagacaacct aggcagccga
       61 acccatcgcg agccccaagg cagcggcagc ccgcacagag agccaggccg aacagagccg
      121 gggccgcagg tgggacttcc gcctcgggac ccggaagaga ccgcgccgtc gctggtggga
      181 gttgtagtcc ggccgtagtt gggggggccc gcggctcatg cgccgtgcac cgaggcttgt
      241 ttcacatctg taacaacagg aggcccagcc tcgtgatgag gaatagcaag gagagaattc
      301 agctccagtt taaaagcctg caaaatcaga gcccctccct gcttttataa gatgaagaca
      361 ggaaaagact gtggtatatg aaactttgtt gacaagagag gatccagaga ctttaaaagc
      421 aaaactctgc tgggcatggt gactcctgtc tgtaattcca gcacttggca gcccaagtct
      481 ttgcagattc ttgaaccagg aatagtaatc aacactcatg gccttttgac cctccttctc
      541 aggattccag ctttctctcc tggccagaaa tgttcagctt ggactcattc agaaaagatc
      601 ggacccagca caggcagcgt caatgcaagc ttcccccacc ccgtcttcca cccatgtgtg
      661 tcaaccctgc ccctggaggg accatcactc gagcttctag ggacctatta aaagagtttc
      721 cgcagcctaa aaaccttctc aacagcgtga ttggaagagc ccttggcatc tcacatgcaa
      781 aagacaagtt agtctatgtg cacacgaatg gaccgaagaa aaagaaagtc accctgcaca
      841 taaagtggcc caagagcgtg gaggtggaag gctatggcag caagaagatt gatgctgagc
      901 gtcaggctgc agcagctgcc tgccaactct tcaagggctg gggtctgctg ggaccacgga
      961 atgagctgtt tgatgcagct aaataccgag tgctagctga tcgttttggg tctccagctg
     1021 acagctggtg gcgcccagaa cccaccatgc ctccaacttc ctggcggcag ctgaatcctg
     1081 agaacattcg gccagggggt cctgcaggac tatcccgatc cttaggccga gaggaagagg
     1141 aagatgagga ggaagagcta gaagagggga ccattgatgt gacagagttt ctgtctatga
     1201 cccagcaaga ctcccacaac ccactcaggg actcaagggg gggctccttt gaaatgacag
     1261 atgatgacag tgctatcaga gctctgaccc agtttccact tcccaagaac ctcctggcca
     1321 aagtgattca gattgcaacc tcctcctcca cagctaagaa tctcatgcag ttccatactg
     1381 tgggtaccaa gaccaagctg gctacactca ctctgctctg gccctgtccc atgacctttg
     1441 ttgccaaagg gcgacgcaaa gctgaggctg agaataaggc agcagccttg gcttgcaaga
     1501 aactgaagag ccttggcctt gtggacagga acaatgagcc gcttacccat gccatgtaca
     1561 acctggcctc cctgcgtgag ttgggtgaga cccagcgccg gccatgtacc atccaggtgc
     1621 ctgagcccat ccttcgcaag atagaggcct tcctgagtca ttacccggtg gacagctcat
     1681 ggatttcccc agaactccga ctgcagagtg atgacatctt gcccttaggc aaggactcag
     1741 ggcccttgag tgaccctatc acaggcaagc catacatgcc cctgtcagaa gcagaggagg
     1801 tgcgcttaag ccagagcctg ctagagctgt ggcggaggag agggccgatc tggcaggagg
     1861 ccccgcagct acctgtagac cctcatcggg acactatcct cagtgccatt gaacaacacc
     1921 cagtggtagt catctctggg gacacaggct gtgggaagac cacacgtatc cctcagctgc
     1981 tattggagcg ctatgtgact gagggtcgag gtgcccgctg caatgtgatc atcacacaac
     2041 ctcgccggat ctcagctgtg tctgtggcac agcgggtcag ccatgaactg ggcccctcct
     2101 tgcgccggaa tgtgggcttc caggtacgct tggaaagtaa gcccccagcc cgaggtgggg
     2161 cgctgctctt ctgcactgtg ggtatcctgc ttcggaagct gcagagcaac cccagcctgg
     2221 agggtgtgag ccatgtcatt gtggatgagg tccatgagcg ggatgtgaac acagacttcc
     2281 tgctgattct gctcaagggc ctgcagcggc tcaacccagc tcttcggctg gtgctcatga
     2341 gtgctacagg agataatgag cgcttttccc gatactttgg gggctgccct gttatcaagg
     2401 tacctggctt catgtatccc gtcaaggaac actacctgga ggacatcttg gccaagctgg
     2461 gtaaacatca gtacccacac cggcatcggc accatgagtc ggaagatgaa tgtgcacttg
     2521 atttggacct tgtgactgac ctggttctgc atatcgatgc ccgtggggaa ccaggtggga
     2581 tcctgtgctt tctacctggc tggcaagaaa tcaaaggagt gcaacaacgg ctccaggagg
     2641 ccctgggcat gcatgaaagc aagtacctca tcttaccagt gcactccaat atccccatga
     2701 tggaccagaa ggccatattc caacagcctc cacttggggt acgcaagatt gtattggcca
     2761 ccaacattgc tgaaacctcc atcacagtta acgacattgt acatgtcgtg gacagcggtc
     2821 tgcacaagga ggaacgctat gacctgaaga ccaaggtgtc ctgcctggag actgtgtggg
     2881 tgtcgagagc aaatgtcatt cagcgccggg gcagggcagg ccgctgccag tcaggttttg
     2941 cctaccactt gttcccgagg agccggctgg agaaaatggt tcctttccaa gtgccagaga
     3001 tcctgcgcac acctcttgag aacctggtgc tgcaagccaa aatccatatg cctgagaaga
     3061 cggcagtgga gttcctctct aaggctgtgg acagtccaaa tatcaaggca gtggatgagg
     3121 ccgtgatcct gctccaggag attggggtgc tggaccagcg ggagtatctg accaccttgg
     3181 gacagcgcct ggcccacatc tctactgacc cccgactggc caaggccata gtgttggctg
     3241 ccatcttccg ttgcctgcac ccactgctgg tggttgtttc ctgccttacc cgggacccct
     3301 tcagcagcag tttgcagaac cgggcagaag tagacaaggt gaaggcattg ctgagccatg
     3361 acagtggcag tgaccatttg gccttcgtgc gggctgtggc tggctgggag gaggtactgc
     3421 gctggcagga ccgtacctcc agggaaaact acctggaaga aaaccttctg tatgccccca
     3481 gcttgcgctt catccacggg ctcatcaagc agttctcaga gaacatttat gaggctttcc
     3541 tagtggggaa gccctctgac tgcacactgc cctctgctca gtgcaatgag tacagcgagg
     3601 aagaggagct ggtgaagggt gtgctgatgg ctggcctcta ccccaacctc atccaggtga
     3661 gacaaggtaa ggttactcgg caaggcaagt tcaaacccaa cagtgtcact tacaggacca
     3721 aatctggcaa catcttgctg cataagtcaa ccattaacag ggaggctacc cggttacgga
     3781 gccgatggct gacatatttc atggccgtca agtccaatgg tagcgtcttt gttcgagatt
     3841 cctcccaggt gcacccacta gctgtgttgc tcctaacaga tggggacgtg cacatccgag
     3901 atgatgggcg tcgggccacc atctcattga gtgacagcga cctgcttcgg ctggaaggtg
     3961 attcacgaac tgtgcggttg ctaagggagt ttcgtcgagc cctaggacgg atggtggagc
     4021 ggagcctccg cagcgagtta gctgcacttc ctcttagtgt gcagcaagaa cacgggcagc
     4081 tgcttgcact gctggcagag ttgcttcgag gaccttgtgg cagctttgat atgcgcaaga
     4141 cagctgatga ctgagcctct cttccgctgg ggctatgtac agagtgcaaa tgtttattta
     4201 aaataaagtt atatttatcc cttgtgag
//
