LOCUS       NM_172594               4456 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus DExH-box helicase 29 (Dhx29), mRNA.
ACCESSION   NM_172594
VERSION     NM_172594.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4456)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 4456)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 4456)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   4  (bases 1 to 4456)
  AUTHORS   Cobellis,G., Nicolaus,G., Iovino,M., Romito,A., Marra,E.,
            Barbarisi,M., Sardiello,M., Di Giorgio,F.P., Iovino,N., Zollo,M.,
            Ballabio,A. and Cortese,R.
  TITLE     Tagging genes with cassette-exchange sites
  JOURNAL   Nucleic Acids Res 33 (4), e44 (2005)
   PUBMED   15741177
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 4456)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK087450.1, BC057112.1 and BC038650.1.
            
            On Jun 19, 2019 this sequence version replaced NM_172594.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC082319.1, SRR1660815.268097.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384, SAMN01164131
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-40                AK087450.1         227-266
            41-4454             BC057112.1         1-4414
            4455-4456           BC038650.1         2496-2497
FEATURES             Location/Qualifiers
     source          1..4456
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 63.93 cM"
     gene            1..4456
                     /gene="Dhx29"
                     /gene_synonym="3732415M03; Ddxx; E130202M19Rik"
                     /note="DExH-box helicase 29"
                     /db_xref="GeneID:218629"
                     /db_xref="MGI:MGI:2145374"
     exon            1..294
                     /gene="Dhx29"
                     /gene_synonym="3732415M03; Ddxx; E130202M19Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             114..4211
                     /gene="Dhx29"
                     /gene_synonym="3732415M03; Ddxx; E130202M19Rik"
                     /EC_number="3.6.4.13"
                     /note="nucleic acid helicase DDXx; DEAH box protein 29;
                     DEAH (Asp-Glu-Ala-His) box polypeptide 29"
                     /codon_start=1
                     /product="ATP-dependent RNA helicase Dhx29"
                     /protein_id="NP_766182.2"
                     /db_xref="CCDS:CCDS26779.1"
                     /db_xref="GeneID:218629"
                     /db_xref="MGI:MGI:2145374"
                     /translation="MGGKNKKHKAPGAAAMRAAVSASRARSAEAGAVGEAQSKKPVAR
                     PAPAVPTGAREPRVKQGPKIYSFNSANDSGGSANLDKSILKVVINNKLEQRIIGVINE
                     HKKQNSDRGAISGRLSAKKLQDLYMALQAFSFKTKDIEDAMTNTLLHGGDLHSALDWL
                     CLNLSDDALPEGFSQEFEEQQPKSRPKFQSVQIQATLSPPQQTKTKRQEEDPKIKPKK
                     EETTVEVNMKEWILRYAEQQDEEEKGEGSKGLEEEEKFDPNQRYLNLAARLLDAKEQA
                     AAFKLEKNKQGQKEAQEKIRKFQREMETLEDHPIFNPAIKISHQQNEKKKPAPATEAE
                     SALNLNLFEKSAAATEEEKGKKKEPHDVRNFDYTARSWTGKSPKQFLIDWVRKNLPKS
                     PNPSFEKVAVGRYWKCRVRVVRSEDDVLVVCPTILTEDGMQAQHLGATLALYRLVKGQ
                     SVHQLLPPTYRDVWLEWSDEEKKREELNKMETNKPRDLFIAKLLNKLKQQQQQQQQQR
                     PESEKGGSEDPEESWENLVSDEDLAALSLEPTSAEDLAPVRSLFRRLQSTPKYQRLLK
                     ERQQLPVFKHRDSIVETLKRHRVVVVAGETGSGKSTQVPHFLLEDLLLDECGARKCNI
                     VCTQPRRISAVSLATRVCEELGCESGPGGRNSLCGYQIRMESRASESTRLLYCTTGVL
                     LRKLQEDGLLADVSHVIVDEVHERSVQSDFLLVILKEILQKRSDLHLILMSATVDSDK
                     FSTYFTHCPILRISGRSYPVEVFHLEDIVEETGFVLEKDSEYCQKFLEEEEEITINVT
                     SKAGGVKKYQEYIPVQSGASPELNPFYQKYSSRTQHAILYMNPHKINLDLILELLVYL
                     DKSPQFRNIEGAVLIFLPGLAHIQQLYDLLSSDRRFYSERYQVIALHSVLSTQDQAAA
                     FMFPPPGVRKIVLATNIAETGITIPDVVFVIDTGRTKENKYHESSQMSSLVETFVSKA
                     SALQRQGRAGRVRDGFCFRLYTRERFEGFLDYSVPEILRVPLEELCLHIMKCDLGSPE
                     DFLSKALDPPQLQVISNAMNLLRKIGACEPNEPKLTPLGQHLAALPVNVKIGKMLIFG
                     AIFGCLEPVATLAAVMTEKSPFITPIGRKDEADLAKSSLAVADSDHLTIYNAYLGWKK
                     AQQEGGFRSEISYCQRNFLNRTSLLTLEDVKQELMKLVKAAGFSSSPSWEGRKGPQTL
                     SFQDIALLKAVLAAGLYDSVGKIMCTKSVDVTEKLACMVETAQGKAQVHPSSVNRDLQ
                     TYGWLLYQEKVRYTRVYLRETTLITPFPVLLFGGDIEVQHRERLLSVDGWIYFQAPVK
                     IAVIFKQLRVLIDSVLRKKLENPKMSLENDKILQIITELIKTENN"
     exon            295..368
                     /gene="Dhx29"
                     /gene_synonym="3732415M03; Ddxx; E130202M19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            369..482
                     /gene="Dhx29"
                     /gene_synonym="3732415M03; Ddxx; E130202M19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            483..612
                     /gene="Dhx29"
                     /gene_synonym="3732415M03; Ddxx; E130202M19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            613..758
                     /gene="Dhx29"
                     /gene_synonym="3732415M03; Ddxx; E130202M19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            759..887
                     /gene="Dhx29"
                     /gene_synonym="3732415M03; Ddxx; E130202M19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            888..1014
                     /gene="Dhx29"
                     /gene_synonym="3732415M03; Ddxx; E130202M19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1015..1173
                     /gene="Dhx29"
                     /gene_synonym="3732415M03; Ddxx; E130202M19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1174..1339
                     /gene="Dhx29"
                     /gene_synonym="3732415M03; Ddxx; E130202M19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1340..1463
                     /gene="Dhx29"
                     /gene_synonym="3732415M03; Ddxx; E130202M19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1464..2075
                     /gene="Dhx29"
                     /gene_synonym="3732415M03; Ddxx; E130202M19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2076..2219
                     /gene="Dhx29"
                     /gene_synonym="3732415M03; Ddxx; E130202M19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2220..2396
                     /gene="Dhx29"
                     /gene_synonym="3732415M03; Ddxx; E130202M19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2397..2537
                     /gene="Dhx29"
                     /gene_synonym="3732415M03; Ddxx; E130202M19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2538..2682
                     /gene="Dhx29"
                     /gene_synonym="3732415M03; Ddxx; E130202M19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2683..2800
                     /gene="Dhx29"
                     /gene_synonym="3732415M03; Ddxx; E130202M19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2801..2885
                     /gene="Dhx29"
                     /gene_synonym="3732415M03; Ddxx; E130202M19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2886..2974
                     /gene="Dhx29"
                     /gene_synonym="3732415M03; Ddxx; E130202M19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2975..3103
                     /gene="Dhx29"
                     /gene_synonym="3732415M03; Ddxx; E130202M19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3104..3179
                     /gene="Dhx29"
                     /gene_synonym="3732415M03; Ddxx; E130202M19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3180..3404
                     /gene="Dhx29"
                     /gene_synonym="3732415M03; Ddxx; E130202M19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3405..3541
                     /gene="Dhx29"
                     /gene_synonym="3732415M03; Ddxx; E130202M19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3542..3635
                     /gene="Dhx29"
                     /gene_synonym="3732415M03; Ddxx; E130202M19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3636..3929
                     /gene="Dhx29"
                     /gene_synonym="3732415M03; Ddxx; E130202M19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3930..4061
                     /gene="Dhx29"
                     /gene_synonym="3732415M03; Ddxx; E130202M19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            4062..4158
                     /gene="Dhx29"
                     /gene_synonym="3732415M03; Ddxx; E130202M19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            4159..4456
                     /gene="Dhx29"
                     /gene_synonym="3732415M03; Ddxx; E130202M19Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4434..4439
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Dhx29"
                     /gene_synonym="3732415M03; Ddxx; E130202M19Rik"
                     /note="hexamer: AATAAA"
     polyA_site      4456
                     /gene="Dhx29"
                     /gene_synonym="3732415M03; Ddxx; E130202M19Rik"
                     /note="major polyA site"
ORIGIN      
        1 atggaggagg ctgggtggag gcgtgggagc cggcaaacgt gaagagctct cgggcttctg
       61 ctgtgccgca gcggggatct ggatctggaa gactactctc ctgcagctga aacatgggcg
      121 gcaaaaataa gaaacacaag gcgccgggag ctgcggcgat gcgggccgcc gtgtctgctt
      181 ccagagccag aagtgcagag gccggagctg ttggggaagc ccagagcaag aagccggtgg
      241 ccaggccggc gcccgccgtc cccaccggcg cccgggagcc ccgagtgaag caaggtccaa
      301 aaatttatag ttttaattct gcaaatgatt ccggtggctc tgcaaatctg gacaaatcta
      361 ttttgaaagt ggtgattaac aataaactag agcaaaggat tatcggagtg atcaatgagc
      421 ataaaaagca gaacagcgac aggggagcga tctctggaag actgtcggct aagaagctac
      481 aggatttata catggcttta caagcgtttt cctttaagac taaggatatt gaagatgcca
      541 tgaccaatac actcttgcat ggaggtgacc ttcattctgc cttggactgg ctctgcttaa
      601 atctttccga tgatgcactt cctgaaggat tcagtcaaga atttgaagag cagcaaccta
      661 aaagcaggcc aaaattccag tctgtacaaa tacaggctac tctttcacct ccacagcaga
      721 cgaaaaccaa aaggcaggag gaagacccta aaattaagcc aaaaaaggaa gagacaaccg
      781 tggaggtgaa tatgaaggag tggattttga gatatgctga gcaacaggac gaagaggaga
      841 agggcgaggg ctctaaaggc ttagaggaag aagaaaagtt tgaccccaac caaaggtact
      901 tgaaccttgc agccagactt ctggacgcaa aggagcaagc cgccgccttc aaactagaaa
      961 aaaacaagca aggccaaaaa gaggctcaag agaaaataag aaagttccaa agagaaatgg
     1021 aaactttaga agaccatcca atattcaacc cagccataaa gatttcacat caacaaaatg
     1081 agaagaaaaa gcctgctcca gccacagaag ctgagagtgc tttaaacctg aatttatttg
     1141 aaaaatctgc agctgctacc gaggaagaga aaggtaaaaa gaaagaacct cacgatgtaa
     1201 ggaactttga ctacactgct cgaagctgga ctggcaaatc tcccaaacaa ttcctcatcg
     1261 actgggtcag gaagaatctt cccaagagtc caaacccctc ctttgagaaa gttgccgtag
     1321 gcagatactg gaaatgtagg gtaagggtcg tcaggtctga agatgacgtg ctggttgtgt
     1381 gtcctacaat cttaaccgag gacggcatgc aagcccagca cctgggagcc acattagccc
     1441 tttatcggct agtgaagggg cagtctgtcc atcagttact ccctcctacg taccgggatg
     1501 tttggctgga gtggagtgat gaagagaaga aaagggaaga actcaataaa atggaaacca
     1561 acaaaccacg ggatcttttt attgccaagc tcttgaataa gttgaagcag cagcagcaac
     1621 aacagcagca gcagcgtcct gaaagcgaga aagggggctc cgaggatccc gaggaatcct
     1681 gggaaaactt agtttccgac gaagatcttg ctgcgctgtc cttggagcca accagtgcag
     1741 aagacctggc acctgttagg agcctcttca ggaggctaca gagcacaccc aagtatcaga
     1801 ggctcctgaa ggagagacag cagctacctg tgttcaaaca ccgggactca attgtggaaa
     1861 ctctgaagag gcaccgggtg gtggtggtag caggtgaaac ggggagtggc aagagcaccc
     1921 aggtgccaca cttcctgttg gaagatctgc tgctcgatga gtgtggagcc aggaagtgta
     1981 acatagtctg cacccagccc cgaagaatct cggcggtgag cttagccacc agggtgtgcg
     2041 aggagctggg ctgtgagagt ggccctggag gaaggaattc tttgtgtggc tatcagatcc
     2101 ggatggaatc tcgagctagt gaatctacca ggctactgta ttgtacaacc ggagttttgc
     2161 taaggaaact tcaggaagat ggtcttctgg ctgatgtgtc tcatgtcatt gtcgatgagg
     2221 tccatgagag aagtgtccag tcagatttcc tgctcgttat cctgaaggag attctgcaga
     2281 agcgttctga cctacacttg attctgatga gcgccaccgt ggacagtgac aagttctcta
     2341 cgtacttcac acactgtcct attctcagaa tttcaggaag aagttaccct gttgaggttt
     2401 ttcatcttga agacatagta gaagaaacag gcttcgtcct ggagaaagac tctgagtatt
     2461 gtcagaagtt tctggaagag gaggaagaaa ttaccattaa tgttacaagt aaagctgggg
     2521 gagtcaaaaa gtatcaggaa tacatcccag ttcagagtgg agcaagtcct gaattaaacc
     2581 cgttctacca aaagtacagt agccgtacgc agcatgcaat tctctacatg aacccccata
     2641 aaatcaacct ggacctcatt ttggagcttc ttgtatactt agacaaaagt cctcagttca
     2701 gaaatattga aggagcagta ttgatcttct tacctggcct tgctcacatt caacagttgt
     2761 atgacctcct gtcaagtgac agaaggtttt attctgagcg gtatcaagtt atagctctgc
     2821 attcagttct ctcaactcaa gatcaagcgg ccgccttcat gttcccccct cccggggtca
     2881 ggaagattgt cttagcaaca aacattgcag agacagggat aactattcct gatgttgtgt
     2941 ttgtcattga cactggacgg acaaaagaaa ataagtacca tgaaagcagc cagatgagct
     3001 ctttggtgga gacctttgtc agtaaagcta gtgccctaca gcgccagggg agagccggga
     3061 gggtccggga tggcttctgc tttcggctgt acacaagaga aagatttgaa ggttttctgg
     3121 actattctgt acctgagatc ctgcgcgtcc ctctggagga actctgtctt cacatcatga
     3181 agtgtgatct gggctcccct gaagacttcc tctccaaagc cttagaccct cctcagcttc
     3241 aagtcatcag caacgcgatg aacttactcc ggaaaattgg agcctgcgaa cccaatgagc
     3301 ctaaactgac accgctgggc cagcaccttg ccgctttgcc tgtcaatgtc aaaattggca
     3361 agatgctcat tttcggagcc atatttggct gtctcgaacc agtggcaaca ctggcagccg
     3421 tgatgacaga gaagtctcca ttcatcacac caattggtcg aaaggatgaa gcggaccttg
     3481 caaagtcgtc tttggctgtg gccgactcgg accacctcac gatctacaat gcttatctag
     3541 ggtggaagaa agcccagcaa gaaggaggct tccgctctga gatctcatat tgccagagga
     3601 acttcctaaa cagaacgtca ctgttgacac tcgaggatgt gaagcaggag ttaatgaaat
     3661 tggtgaaagc tgcaggattt tcatcgtctc ccagctggga gggaaggaaa gggccgcaga
     3721 cgctctcttt ccaggacatt gctcttctta aagctgtgct ggctgctggc ctgtacgaca
     3781 gtgtggggaa gatcatgtgt acaaagtccg tggacgtgac agagaagctg gcgtgcatgg
     3841 tggagacagc ccaaggcaaa gctcaggtgc acccgtcctc tgtaaaccgg gacctacaaa
     3901 cctacgggtg gctcttgtac caggagaagg tgaggtacac cagagtctac ctgagagaga
     3961 cgaccctcat cacccctttt ccagttttgc tttttggagg tgacatagaa gtccagcacc
     4021 gagagcggct tctgtctgtg gacggctgga tctattttca ggccccggta aagatagctg
     4081 tcatttttaa gcagctaaga gttctcattg attctgtttt aagaaaaaaa cttgaaaatc
     4141 caaagatgtc ccttgaaaat gacaagattc tacagatcat tacagaattg ataaaaacag
     4201 agaataattg acactggaat ccacggttgt ctgcttgtaa agttaagata aagatacggt
     4261 cctgaaatga tgtggaggtc agctgtccca ctaagtattt cattacctaa aatgttggtt
     4321 ctggccatta acctgaagac ggcggggagg gaaagagcac attctttcaa cgtggacttt
     4381 tctagctcct ttgtaacgat gatgatactc aatgtatttg ccatgacatt tacaataaat
     4441 cctttggtat caatca
//
