LOCUS       NM_001033326            1926 bp    mRNA    linear   ROD 06-OCT-2024
DEFINITION  Mus musculus dehydrogenase/reductase X linked (Dhrsx), transcript
            variant 1, mRNA.
ACCESSION   NM_001033326 XM_135485
VERSION     NM_001033326.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1926)
  AUTHORS   Gianfrancesco,F., Sanges,R., Esposito,T., Tempesta,S., Rao,E.,
            Rappold,G., Archidiacono,N., Graves,J.A., Forabosco,A. and
            D'Urso,M.
  TITLE     Differential divergence of three human pseudoautosomal genes and
            their mouse homologs: implications for sex chromosome evolution
  JOURNAL   Genome Res 11 (12), 2095-2100 (2001)
   PUBMED   11731500
REFERENCE   2  (bases 1 to 1926)
  AUTHORS   Bachmanov,A.A., Li,X., Reed,D.R., Ohmen,J.D., Li,S., Chen,Z.,
            Tordoff,M.G., de Jong,P.J., Wu,C., West,D.B., Chatterjee,A.,
            Ross,D.A. and Beauchamp,G.K.
  TITLE     Positional cloning of the mouse saccharin preference (Sac) locus
  JOURNAL   Chem Senses 26 (7), 925-933 (2001)
   PUBMED   11555487
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CAAA01125276.1 and CAAA01118383.1.
            
            On Feb 1, 2019 this sequence version replaced NM_001033326.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC046917.1, AK157461.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-250               CAAA01125276.1     4131-4380
            251-358             CAAA01118383.1     6149-6256
            359-427             CAAA01118383.1     6509-6577
            428-529             CAAA01118383.1     6820-6921
            530-737             CAAA01118383.1     9588-9795
            738-945             CAAA01118383.1     10074-10281
            946-1926            CAAA01118383.1     10683-11663
FEATURES             Location/Qualifiers
     source          1..1926
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4"
     gene            1..1926
                     /gene="Dhrsx"
                     /gene_synonym="D4Ertd296e; Dhrsxy; Pscad"
                     /note="dehydrogenase/reductase X linked"
                     /db_xref="GeneID:236082"
                     /db_xref="MGI:MGI:2181510"
     exon            1..250
                     /gene="Dhrsx"
                     /gene_synonym="D4Ertd296e; Dhrsxy; Pscad"
                     /inference="alignment:Splign:2.1.0"
     CDS             142..1149
                     /gene="Dhrsx"
                     /gene_synonym="D4Ertd296e; Dhrsxy; Pscad"
                     /note="isoform 1 is encoded by transcript variant 1;
                     dehydrogenase/reductase SDR family member on chromosome X
                     homolog; SCAD family protein; dehydrogenase/reductase (SDR
                     family) X chromosome; dolichal reductase;
                     dehydrogenase/reductase SDR family member on chromosome Y;
                     polyprenol dehydrogenase"
                     /codon_start=1
                     /product="polyprenol dehydrogenase isoform 1"
                     /protein_id="NP_001028498.2"
                     /db_xref="GeneID:236082"
                     /db_xref="MGI:MGI:2181510"
                     /translation="MSTLRALRAVLCVYAVGIAVALAQLLRRLRGDFRPPVLPPQPGR
                     VAIVTGATAGIGRSTARQLARLGMCVVVAGNDEHCGQEVVSSIRAEMGSDRAHFLPLD
                     LASLASVRGFARDFRALGLPLHLLVNNAGVMLEPRAETEDGFERHLGVNFLGHFLLTL
                     LLLPALRASGAEGRGSRVVTVGSATHYVGTVDMADLHGRHAYSPYAAYAQSKLALALF
                     ALQLQRILDARGDPVTSNMADPGVVDTELYRHAGWVLRTVKRFLGWLVFKSPEEGAWT
                     LVYAAAAPELEGVGGRYLRDEAEAEPLGTARDQELQRRLWAEGLRLTGAGGGDSDGVA
                     W"
     exon            251..358
                     /gene="Dhrsx"
                     /gene_synonym="D4Ertd296e; Dhrsxy; Pscad"
                     /inference="alignment:Splign:2.1.0"
     exon            359..427
                     /gene="Dhrsx"
                     /gene_synonym="D4Ertd296e; Dhrsxy; Pscad"
                     /inference="alignment:Splign:2.1.0"
     exon            428..529
                     /gene="Dhrsx"
                     /gene_synonym="D4Ertd296e; Dhrsxy; Pscad"
                     /inference="alignment:Splign:2.1.0"
     exon            530..737
                     /gene="Dhrsx"
                     /gene_synonym="D4Ertd296e; Dhrsxy; Pscad"
                     /inference="alignment:Splign:2.1.0"
     exon            738..945
                     /gene="Dhrsx"
                     /gene_synonym="D4Ertd296e; Dhrsxy; Pscad"
                     /inference="alignment:Splign:2.1.0"
     exon            946..1926
                     /gene="Dhrsx"
                     /gene_synonym="D4Ertd296e; Dhrsxy; Pscad"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1188..1193
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Dhrsx"
                     /gene_synonym="D4Ertd296e; Dhrsxy; Pscad"
                     /note="hexamer: AATAAA"
     polyA_site      1206
                     /gene="Dhrsx"
                     /gene_synonym="D4Ertd296e; Dhrsxy; Pscad"
                     /note="major polyA site"
     regulatory      1901..1906
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Dhrsx"
                     /gene_synonym="D4Ertd296e; Dhrsxy; Pscad"
                     /note="hexamer: AATAAA"
     polyA_site      1924
                     /gene="Dhrsx"
                     /gene_synonym="D4Ertd296e; Dhrsxy; Pscad"
                     /note="major polyA site"
ORIGIN      
        1 ggcatccctt atgcctcccg cgtcatcacg cgcggtcagc gctgaggctc ctgggagctc
       61 ccggggacgc ggggcccgcg gtgactgaca aacaccagcg cagtgttccg aggcggcggc
      121 gacacttccg ggggcggggc catgtccacc ttgcgagcgc tgcgggccgt gctctgcgtc
      181 tacgccgtgg gcatcgcggt ggcgctggcg cagcttctgc gcaggctccg cggcgacttc
      241 cggccgccgg ttcttccccc ccagccgggc cgtgtggcca tcgtgacagg ggcgacagct
      301 ggcatcgggc gtagcaccgc gaggcagctg gcgcggctgg gcatgtgcgt ggtcgtggcc
      361 ggcaatgacg agcactgcgg acaggaagtt gtcagctcca tccgggccga gatggggagc
      421 gaccgagcgc acttcttgcc cctggacctc gcctccctgg cctccgtccg aggcttcgcc
      481 cgcgacttcc gggcgctggg actccccctg cacctgctcg tcaacaacgc gggcgtgatg
      541 ctggagccgc gggctgagac tgaggacggc ttcgagcgcc acctgggtgt gaacttcctg
      601 ggccacttcc tgctgacgct gctgctcctc cccgccttgc gcgcgtcagg ggccgagggg
      661 cggggctcgc gtgtcgtcac cgtggggtcg gccacacact acgtgggcac cgtggacatg
      721 gccgaccttc acgggcgcca cgcctactcc ccgtacgcag cctacgcgca gagcaagctc
      781 gccctcgccc tgttcgccct acagctgcag cgcatcctgg acgcccgcgg tgaccctgtg
      841 acctccaaca tggccgaccc cggcgtggtc gacaccgagc tgtaccggca cgcggggtgg
      901 gtcttgcgca cggtgaagcg gttcctcggg tggctcgttt tcaagagccc ggaggagggc
      961 gcgtggacgt tggtgtacgc ggcggccgcc ccggagctag aaggtgtcgg aggtcgctac
     1021 ctgcgtgacg aggccgaggc agagccgctg gggaccgcgc gggaccagga gctgcagcgg
     1081 cggctgtggg ccgagggcct caggctgacg ggcgcggggg gcggggacag cgatggcgtg
     1141 gcgtggtgac ggcgtcagtg tggggtgggc gggtcccgga gttgagaaat aaacaacgtg
     1201 tccatgcccc tgcctcagct cacaactgtg tgtgtgtggg aggggggtga gggtggacgg
     1261 gctctcctca ccacttcctg tctgactcca tgtgacctct gtgaactcga tgacctctgt
     1321 ggcctctggt gacctcagat gaccccaagt tgcccagcct gaaccatctt gacgccaatg
     1381 acctctgtga cctttcatga ccccagatga cccccaaatg gctccaagtg gcctcaggga
     1441 accacataac ccctgtgacc tcaccttgac ctcagtgact tcctgtgacc acggtgaccc
     1501 ccacctgacc cccatattcc aaccttagcc actttttggc cgctgtgacg cctgtgacct
     1561 cgtgtgaccc tagatgaccc cacgtgacct cagtcacccg ccttgagcca gcttgacccc
     1621 ggtgacctct ctgacctgcc atgacccctg acctgccgtg acgccggatg actctacttg
     1681 acctcggtga ccctgcgtga cccctaggat cggacctcac acagccgagg ttttacccaa
     1741 cagactggca ccgtgaatga ctcgtcctcg tgtccttcgt ggtttgacag agtcacccgg
     1801 ggagcaagca gacgtttagg tggtcgttaa aaacgtgact acaaatttat tatacaatat
     1861 gcctttatga aaatattaaa acgggggaga gtttccaaaa aataaaaaaa taaaattaaa
     1921 aaaaca
//
