LOCUS       NM_025522               1318 bp    mRNA    linear   ROD 03-JUN-2024
DEFINITION  Mus musculus dehydrogenase/reductase 7 (Dhrs7), mRNA.
ACCESSION   NM_025522
VERSION     NM_025522.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1318)
  AUTHORS   Rattner,A., Terrillion,C.E., Jou,C., Kleven,T., Hu,S.F.,
            Williams,J., Hou,Z., Aggarwal,M., Mori,S., Shin,G., Goff,L.A.,
            Witter,M.P., Pletnikov,M., Fenton,A.A. and Nathans,J.
  TITLE     Developmental, cellular, and behavioral phenotypes in a mouse model
            of congenital hypoplasia of the dentate gyrus
  JOURNAL   Elife 9, e62766 (2020)
   PUBMED   33084572
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1318)
  AUTHORS   Velecela,V., Torres-Cano,A., Garcia-Melero,A., Ramiro-Pareta,M.,
            Muller-Sanchez,C., Segarra-Mondejar,M., Chau,Y.Y.,
            Campos-Bonilla,B., Reina,M., Soriano,F.X., Hastie,N.D.,
            Martinez,F.O. and Martinez-Estrada,O.M.
  TITLE     Epicardial cell shape and maturation are regulated by Wt1 via
            transcriptional control of Bmp4
  JOURNAL   Development 146 (20) (2019)
   PUBMED   31624071
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CX223953.1, AK014100.1 and CF586466.1.
            
            On Apr 18, 2009 this sequence version replaced NM_025522.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC016189.1, AK014100.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN00849382
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-107               CX223953.1         1-107
            108-1301            AK014100.1         63-1256
            1302-1318           CF586466.1         25-41               c
FEATURES             Location/Qualifiers
     source          1..1318
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="12"
                     /map="12 30.23 cM"
     gene            1..1318
                     /gene="Dhrs7"
                     /gene_synonym="2310016E22Rik; 5730564L20Rik; Retdsr4;
                     Retsdr4"
                     /note="dehydrogenase/reductase 7"
                     /db_xref="GeneID:66375"
                     /db_xref="MGI:MGI:1913625"
     exon            1..200
                     /gene="Dhrs7"
                     /gene_synonym="2310016E22Rik; 5730564L20Rik; Retdsr4;
                     Retsdr4"
                     /inference="alignment:Splign:2.1.0"
     CDS             68..1084
                     /gene="Dhrs7"
                     /gene_synonym="2310016E22Rik; 5730564L20Rik; Retdsr4;
                     Retsdr4"
                     /note="retinal short-chain dehydrogenase/reductase 4;
                     short chain dehydrogenase/reductase family 34C member 1;
                     dehydrogenase/reductase (SDR family) member 7"
                     /codon_start=1
                     /product="dehydrogenase/reductase SDR family member 7
                     precursor"
                     /protein_id="NP_079798.2"
                     /db_xref="CCDS:CCDS49086.1"
                     /db_xref="GeneID:66375"
                     /db_xref="MGI:MGI:1913625"
                     /translation="MSWELLLWLLALCALILPLVQLLRFLRADADLTLLWAEWQGRRP
                     EWELTDMVVWVTGASSGIGEELAFQLSKLGVSLVLSARRAQELERVKRRCLENGNLKE
                     KDILVLPLDLTDTSSHEAATKAVLQEFGKIDILVNNGGRSQRSLVLETNLDVFKELIN
                     LNYIGTVSLTKCVLPHMIERKQGKIVTVNSIAGIASVSLSSGYCASKHALRGFFNALH
                     SELGQYPGITFCNVYPGPVQSDIVKNAFTEEVTKSMRNNIDQSYKMPTSRCVRLMLIS
                     MANDLKEVWISDHPVLLGAYIWQYMPTWAAWLNCKLGKERIQNFKNNLDPDLPYKFLK
                     AKKD"
     exon            201..353
                     /gene="Dhrs7"
                     /gene_synonym="2310016E22Rik; 5730564L20Rik; Retdsr4;
                     Retsdr4"
                     /inference="alignment:Splign:2.1.0"
     exon            354..460
                     /gene="Dhrs7"
                     /gene_synonym="2310016E22Rik; 5730564L20Rik; Retdsr4;
                     Retsdr4"
                     /inference="alignment:Splign:2.1.0"
     exon            461..700
                     /gene="Dhrs7"
                     /gene_synonym="2310016E22Rik; 5730564L20Rik; Retdsr4;
                     Retsdr4"
                     /inference="alignment:Splign:2.1.0"
     exon            701..823
                     /gene="Dhrs7"
                     /gene_synonym="2310016E22Rik; 5730564L20Rik; Retdsr4;
                     Retsdr4"
                     /inference="alignment:Splign:2.1.0"
     exon            824..1039
                     /gene="Dhrs7"
                     /gene_synonym="2310016E22Rik; 5730564L20Rik; Retdsr4;
                     Retsdr4"
                     /inference="alignment:Splign:2.1.0"
     exon            1040..1304
                     /gene="Dhrs7"
                     /gene_synonym="2310016E22Rik; 5730564L20Rik; Retdsr4;
                     Retsdr4"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1225..1230
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Dhrs7"
                     /gene_synonym="2310016E22Rik; 5730564L20Rik; Retdsr4;
                     Retsdr4"
                     /note="hexamer: AATAAA"
     polyA_site      1247
                     /gene="Dhrs7"
                     /gene_synonym="2310016E22Rik; 5730564L20Rik; Retdsr4;
                     Retsdr4"
                     /note="major polyA site"
     regulatory      1284..1289
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Dhrs7"
                     /gene_synonym="2310016E22Rik; 5730564L20Rik; Retdsr4;
                     Retsdr4"
                     /note="hexamer: AATAAA"
     polyA_site      1304
                     /gene="Dhrs7"
                     /gene_synonym="2310016E22Rik; 5730564L20Rik; Retdsr4;
                     Retsdr4"
ORIGIN      
        1 cgccgcgtag agggcgggcg ccgactgtct tccgcttgcg gcagagtcgg gtaggcaagg
       61 gacagcgatg agctgggagc tgctgttgtg gctgctggcg ctgtgcgcgc tgatcctgcc
      121 ccttgtgcag ctcttgcgct ttttgcgggc ggatgcggac ctgaccttgt tgtgggctga
      181 atggcaaggg cgacgcccag aatgggagct gactgacatg gtggtgtggg ttactggagc
      241 gtcaagtggc attggcgagg agctagcttt ccagttatct aaactcgggg tctctctggt
      301 gctgtcagcc cgaagggcgc aggagctgga gcgggtgaag agaagatgcc tggaaaatgg
      361 caatttaaaa gaaaaagata tactggttct gccccttgac ttgaccgata caagttccca
      421 tgaggcagcc accaaagccg ttctgcagga gtttggtaaa attgacattt tggtcaacaa
      481 cggtggaaga agccagcgtt ccttagttct agaaaccaac ttggatgtct tcaaggagct
      541 gataaatctg aactacatag ggacagtatc cttgaccaag tgtgtcctgc ctcacatgat
      601 agagaggaaa caagggaaga ttgtgactgt gaacagcatc gcggggattg cctctgtgtc
      661 cctttccagt ggctactgtg ccagcaagca tgctcttcgg ggttttttca atgccctcca
      721 tagtgagctc ggccaatatc caggcataac attttgcaac gtttacccgg ggcctgtgca
      781 gtccgacatt gtgaagaatg ccttcaccga ggaagtaact aagtctatga gaaacaacat
      841 agaccagagt tacaagatgc caacgagccg ctgtgtgcgg ctgatgctca tctccatggc
      901 caatgatctg aaggaagtct ggatctctga ccatcctgtg ctgttggggg catacatatg
      961 gcagtatatg ccaacctggg ccgcatggct aaactgcaag ttggggaagg aaagaatcca
     1021 aaactttaag aataatttgg atccagactt gccttataaa ttcttgaagg caaagaagga
     1081 ttgaaacaac caccagagat gtctgagcca cttgttgaga atgaaaaaca gcgtatgtac
     1141 agtaagcttg cacacagaag gagggccggt gactactttc gggtttaatt tttgatacaa
     1201 ctttctattc agtatgtaat gaataataaa gaaaactttg tcctgtatct tgcctttgta
     1261 caagagcata tggtaccttt ttgaataaaa taacatttaa cataaaaaaa aaaaaaaa
//
