LOCUS       NM_027903               2747 bp    mRNA    linear   ROD 01-AUG-2024
DEFINITION  Mus musculus dihydrodiol dehydrogenase (Dhdh), mRNA.
ACCESSION   NM_027903
VERSION     NM_027903.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2747)
  AUTHORS   Newton,M.F., Nash,H.R., Peters,J. and Andrews,S.J.
  TITLE     Xylose dehydrogenase-1, a new gene on mouse chromosome 7
  JOURNAL   Biochem Genet 20 (7-8), 733-745 (1982)
   PUBMED   6753830
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC151602.4.
            
            On Feb 13, 2018 this sequence version replaced NM_027903.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK154452.1, AK005050.2 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164140, SAMN01164142
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-132               AC151602.4         101659-101790
            133-244             AC151602.4         102293-102404
            245-408             AC151602.4         103560-103723
            409-661             AC151602.4         108423-108675
            662-786             AC151602.4         111331-111455
            787-934             AC151602.4         114712-114859
            935-2747            AC151602.4         115089-116901
FEATURES             Location/Qualifiers
     source          1..2747
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 29.32 cM"
     gene            1..2747
                     /gene="Dhdh"
                     /gene_synonym="1300018L09Rik; B830008H07Rik; Xld-1; Xld1"
                     /note="dihydrodiol dehydrogenase"
                     /db_xref="GeneID:71755"
                     /db_xref="MGI:MGI:1919005"
     exon            1..132
                     /gene="Dhdh"
                     /gene_synonym="1300018L09Rik; B830008H07Rik; Xld-1; Xld1"
                     /inference="alignment:Splign:2.1.0"
     CDS             43..1044
                     /gene="Dhdh"
                     /gene_synonym="1300018L09Rik; B830008H07Rik; Xld-1; Xld1"
                     /EC_number="1.3.1.20"
                     /EC_number="1.1.1.179"
                     /note="D-xylose 1-dehydrogenase; D-xylose-NADP
                     dehydrogenase; dimeric dihydrodiol dehydrogenase; xylose
                     dehydrogenase 1; dihydrodiol dehydrogenase (dimeric)"
                     /codon_start=1
                     /product="trans-1,2-dihydrobenzene-1,2-diol dehydrogenase"
                     /protein_id="NP_082179.1"
                     /db_xref="CCDS:CCDS21247.1"
                     /db_xref="GeneID:71755"
                     /db_xref="MGI:MGI:1919005"
                     /translation="MALRWGIVSAGLIANDFTTVLSSLPSSEHQVVAVAARDLNRAEE
                     FAQKFNIPKAYGSYEELAKDPNVEVAYIATQHPQHKPAVLLCLAAGKAVLCEKPMGVN
                     AAEVREMVAKARSQGVFLMEAIWSRFFPAMEALREVLVQGTIGDLRVARAEFGFDLSH
                     IPRATDWNQAGGGLLDLGIYCVQFLSMIFGAQKPEKISAVGRIHETGVDDTVSVLLQY
                     PGGVHGSFTCSISSNLPNTAYVSGTKGMAQIQKLWAPTELVVNGERKEFPPPVLGKDY
                     NFVNGSCMLYEANHVRECLRKGLKESPVVPLAESELLAEILEEARKAIGVTFPQDKR"
     exon            133..244
                     /gene="Dhdh"
                     /gene_synonym="1300018L09Rik; B830008H07Rik; Xld-1; Xld1"
                     /inference="alignment:Splign:2.1.0"
     exon            245..408
                     /gene="Dhdh"
                     /gene_synonym="1300018L09Rik; B830008H07Rik; Xld-1; Xld1"
                     /inference="alignment:Splign:2.1.0"
     exon            409..661
                     /gene="Dhdh"
                     /gene_synonym="1300018L09Rik; B830008H07Rik; Xld-1; Xld1"
                     /inference="alignment:Splign:2.1.0"
     exon            662..786
                     /gene="Dhdh"
                     /gene_synonym="1300018L09Rik; B830008H07Rik; Xld-1; Xld1"
                     /inference="alignment:Splign:2.1.0"
     exon            787..934
                     /gene="Dhdh"
                     /gene_synonym="1300018L09Rik; B830008H07Rik; Xld-1; Xld1"
                     /inference="alignment:Splign:2.1.0"
     exon            935..2747
                     /gene="Dhdh"
                     /gene_synonym="1300018L09Rik; B830008H07Rik; Xld-1; Xld1"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      1126
                     /gene="Dhdh"
                     /gene_synonym="1300018L09Rik; B830008H07Rik; Xld-1; Xld1"
                     /note="major polyA site"
     regulatory      1424..1429
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Dhdh"
                     /gene_synonym="1300018L09Rik; B830008H07Rik; Xld-1; Xld1"
                     /note="hexamer: ATTACA"
     polyA_site      1445
                     /gene="Dhdh"
                     /gene_synonym="1300018L09Rik; B830008H07Rik; Xld-1; Xld1"
     regulatory      1460..1465
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Dhdh"
                     /gene_synonym="1300018L09Rik; B830008H07Rik; Xld-1; Xld1"
                     /note="hexamer: AATAAA"
     polyA_site      1478
                     /gene="Dhdh"
                     /gene_synonym="1300018L09Rik; B830008H07Rik; Xld-1; Xld1"
     regulatory      2139..2144
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Dhdh"
                     /gene_synonym="1300018L09Rik; B830008H07Rik; Xld-1; Xld1"
                     /note="hexamer: AACAAA"
     polyA_site      2159
                     /gene="Dhdh"
                     /gene_synonym="1300018L09Rik; B830008H07Rik; Xld-1; Xld1"
ORIGIN      
        1 gttggccccg cctccggccc ccgcaggcag aagacgtgca aaatggcgct gcgctggggc
       61 atcgtgtcgg ctggcttaat tgccaacgac tttaccaccg tgctgagctc actgccttcc
      121 tcggagcacc aggtggtagc ggtagctgcg agggacctga accgggccga ggagttcgca
      181 cagaaattca acatccccaa ggcctatggc tcttatgagg aactggccaa ggacccaaac
      241 gtggaggtgg cctacatcgc cacccagcac ccccagcaca agccagccgt actcctctgc
      301 ctggcagcag gcaaggctgt cctttgtgag aaacccatgg gcgtgaatgc agcagaagtt
      361 cgggagatgg ttgccaaagc ccgttctcaa ggcgtcttcc ttatggaggc catttggagc
      421 cgattttttc ctgccatgga ggctctgagg gaagttttag ttcaaggaac tatcggagac
      481 ctacgagtgg cccgggcaga attcggattt gatttaagtc atataccccg ggccacagac
      541 tggaaccaag ccggaggtgg tctgctggac ctaggcatct actgtgtcca gttcttatcc
      601 atgatctttg gtgcacagaa gccagagaag atttcagctg ttgggaggat ccatgaaaca
      661 ggtgtggatg acactgtcag cgtgctactt cagtatccag gaggggttca tggcagcttc
      721 acctgcagca tctcctccaa cctccccaac acagcgtatg tgagtggtac caagggcatg
      781 gcccagattc aaaaattgtg ggccccaaca gagctggtgg tgaatggaga gaggaaggag
      841 ttccctccgc ctgtccttgg gaaggactac aattttgtaa atgggtcatg catgctctat
      901 gaagccaacc acgtgcgtga gtgcctgcgt aaaggtctta aggagagtcc tgtagttcct
      961 ctggcagaga gtgagctctt ggctgagatc cttgaggagg cgaggaaggc cattggagtc
     1021 accttccccc aggataaacg ctgatacagc tcctgcgaca gatgtgtgtg gcaagcaacc
     1081 ttccctcctg cttggacctc tgtaacctga ctctcattgc tttggagttg ttgttgttgt
     1141 tgttgttgtt gctgctgctg ctgctgcaaa tcagcacgtg ttctctccct ttctgggtgt
     1201 tgggagccag ctttgatgag tcagggtgtg gagtcagggg agtctacaga caccaaagct
     1261 tctttctagg acaaacaggt tctctcttta ctttaggggg aaacacacgc acacgcacac
     1321 gcacacgcac acacacacac acacacttga tggatgaagc taggctccaa caactttatt
     1381 tttcccccat atcccccagc aaactctttg aagaagtata aaaattacaa tgtggttaca
     1441 ttctatcttt aagtggatga ataaatgaag tacaatgagt tcaagtaaaa acaacaacta
     1501 caaagcccag caggccccca gcacccttac acaattaagc aatttatata ttacatgcag
     1561 aaaacagatt attaacatga atccacatac attcctgtct aagcaacttg ttatagacta
     1621 acaaactgtg ggtaaaaaag gtattttttt ctcagccagt tctttgactg gcaagctgca
     1681 atttgtgatt atgaagaaag gaacaatcat tttgttattt gtcctgaaaa gtaattttta
     1741 aaattattca ctttacaccc cagtatcagc cccacctatc tcctcccagt cctcccttca
     1801 cacagctcag ctcccccccc attccctctc ttcctctgag aagggggaag ctcccctggg
     1861 taccacacac acacacacac acacacactc acacacacac acacaaacac actcacacac
     1921 acacacacac acacacacac agcatatgga gtcactgcag gactaagtgc atcctctccc
     1981 actgaagcca gatgaaacag cccagttagg ggaatgggat ccacaggcag gcaatagatt
     2041 caggaactaa atgtaatcat aaaaaactta aagaatcaca aatctaaact tttatataaa
     2101 aaaaacagtc ctttctactt taaatcctcg ggtacataaa caaaaacctg tttctggttg
     2161 cggtgtggtt cagcccttgg catatacacc tttaattcaa aacaatggag gtaaagttag
     2221 tttgtaaaag gaagcaccca tgtttgaaag tgatgtctaa ttgagtggca agcaacaaat
     2281 cagatttgac agactaggat gtgcccagct cccatgagag cagagaggag agagagagag
     2341 actgctttaa gagagcaagg cagggcgata ggaaggagga ggaggcaggc tactgctaca
     2401 gagacaggtt gaacagagaa caagctagac tcaggggaag acagaacaag ccagggagtg
     2461 agaaggagcc agaagataag aacacattgc cagagttagt ttgaggccaa gcagaacaac
     2521 ccagttagag gctgagagaa gccagactgg atcagtcagc ttagaaagga gtttgagcca
     2581 gaacaactga gttcagaaag aaaaagctta ttcagagtaa gtctcagagg ctgaaacagt
     2641 gtagacctag ataagattgt gcggaggcta gaagcttgca ggcctagggt caactatcaa
     2701 aagtgtgctc ttctaaattt aaattgttcc ccaagatttt ctacatt
//
