LOCUS       NM_138650               5521 bp    mRNA    linear   ROD 18-JUN-2024
DEFINITION  Mus musculus diacylglycerol kinase, gamma (Dgkg), transcript
            variant 1, mRNA.
ACCESSION   NM_138650
VERSION     NM_138650.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5521)
  AUTHORS   Chen,H., Luo,S., Deng,X., Li,S., Mao,Y., Yan,J., Cheng,Y., Liu,X.,
            Pan,J. and Huang,H.
  TITLE     Pre-eclamptic foetal programming predisposes offspring to hepatic
            steatosis via DNA methylation
  JOURNAL   Biochim Biophys Acta Mol Basis Dis 1870 (5), 167189 (2024)
   PUBMED   38648899
REFERENCE   2  (bases 1 to 5521)
  AUTHORS   Zhang,L., Xu,J., Zhou,S., Yao,F., Zhang,R., You,W., Dai,J., Yu,K.,
            Zhang,Y., Baheti,T., Pu,L., Xu,J., Qian,X., Zhang,C., Xia,Y.,
            Dai,X., Li,Q. and Wang,X.
  TITLE     Endothelial DGKG promotes tumor angiogenesis and immune evasion in
            hepatocellular carcinoma
  JOURNAL   J Hepatol 80 (1), 82-98 (2024)
   PUBMED   37838036
  REMARK    GeneRIF: Endothelial DGKG promotes tumor angiogenesis and immune
            evasion in hepatocellular carcinoma.
REFERENCE   3  (bases 1 to 5521)
  AUTHORS   Tsumagari,R., Maruo,K., Kakizawa,S., Ueda,S., Yamanoue,M.,
            Saito,H., Suzuki,N. and Shirai,Y.
  TITLE     Precise Regulation of the Basal PKCgamma Activity by DGKgamma Is
            Crucial for Motor Coordination
  JOURNAL   Int J Mol Sci 21 (21), 7866 (2020)
   PUBMED   33114041
  REMARK    GeneRIF: Precise Regulation of the Basal PKCgamma Activity by
            DGKgamma Is Crucial for Motor Coordination.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 5521)
  AUTHORS   Tsumagari,R., Kakizawa,S., Kikunaga,S., Fujihara,Y., Ueda,S.,
            Yamanoue,M., Saito,N., Ikawa,M. and Shirai,Y.
  TITLE     DGKgamma Knock-Out Mice Show Impairments in Cerebellar Motor
            Coordination, LTD, and the Dendritic Development of Purkinje Cells
            through the Activation of PKCgamma
  JOURNAL   eNeuro 7 (2) (2020)
   PUBMED   32033984
  REMARK    GeneRIF: DGKgamma Knock-Out Mice Show Impairments in Cerebellar
            Motor Coordination, LTD, and the Dendritic Development of Purkinje
            Cells through the Activation of PKCgamma.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 5521)
  AUTHORS   Isozaki,T., Komenoi,S., Lu,Q., Usuki,T., Tomokata,S., Matsutomo,D.,
            Sakai,H., Bando,K., Kiyonari,H. and Sakane,F.
  TITLE     Deficiency of diacylglycerol kinase eta induces lithium-sensitive
            mania-like behavior
  JOURNAL   J Neurochem 138 (3), 448-456 (2016)
   PUBMED   27167678
REFERENCE   6  (bases 1 to 5521)
  AUTHORS   Kalcheva,I., Elliott,R.W., Dalziel,M. and Lau,J.T.
  TITLE     The gene encoding beta-galactoside alpha2,6-sialyltransferase maps
            to mouse chromosome 16
  JOURNAL   Mamm Genome 8 (8), 619-620 (1997)
   PUBMED   9250875
REFERENCE   7  (bases 1 to 5521)
  AUTHORS   Saba-el-Leil,M.K., Malo,D. and Meloche,S.
  TITLE     Chromosomal localization of the mouse genes encoding the ERK1 and
            ERK2 isoforms of MAP kinases
  JOURNAL   Mamm Genome 8 (2), 141-142 (1997)
   PUBMED   9060415
REFERENCE   8  (bases 1 to 5521)
  AUTHORS   Burgess,D.L., Rafael,J.A., Meisler,M.H. and Chamberlain,J.S.
  TITLE     Dlgh1, a mouse homolog of the drosophila discs-large gene, is
            located on chromosome 16
  JOURNAL   Mamm Genome 7 (8), 623-624 (1996)
   PUBMED   8678991
REFERENCE   9  (bases 1 to 5521)
  AUTHORS   Fitzgibbon,J., Wells,D., Pilz,A., Delhanty,J., Kai,M., Kanoh,H. and
            Hunt,D.
  TITLE     Localisation of the gene encoding diacylglycerol kinase 3 (DAGK3)
            to human chromosome 3q27-28 and mouse chromosome 16
  JOURNAL   Curr Eye Res 14 (11), 1041-1043 (1995)
   PUBMED   8585934
REFERENCE   10 (bases 1 to 5521)
  AUTHORS   Pilz,A., Schaap,D., Hunt,D. and Fitzgibbon,J.
  TITLE     Chromosomal localization of three mouse diacylglycerol kinase
            (DAGK) genes: genes sharing sequence homology to the Drosophila
            retinal degeneration A (rdgA) gene
  JOURNAL   Genomics 26 (3), 599-601 (1995)
   PUBMED   7607687
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY724037.1, AK220294.1, AK013697.1 and BU700613.1.
            
            On Jul 19, 2008 this sequence version replaced NM_138650.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK220294.1, SRR14995048.1500899.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-58                BY724037.1         1-58
            59-3613             AK220294.1         1-3555
            3614-5350           AK013697.1         246-1982
            5351-5521           BU700613.1         1-171               c
FEATURES             Location/Qualifiers
     source          1..5521
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="16"
                     /map="16 13.37 cM"
     gene            1..5521
                     /gene="Dgkg"
                     /gene_synonym="2900055E17Rik; 90kDa; Dagk3; E430001K23Rik;
                     mKIAA4131"
                     /note="diacylglycerol kinase, gamma"
                     /db_xref="GeneID:110197"
                     /db_xref="MGI:MGI:105060"
     exon            1..283
                     /gene="Dgkg"
                     /gene_synonym="2900055E17Rik; 90kDa; Dagk3; E430001K23Rik;
                     mKIAA4131"
                     /inference="alignment:Splign:2.1.0"
     exon            284..525
                     /gene="Dgkg"
                     /gene_synonym="2900055E17Rik; 90kDa; Dagk3; E430001K23Rik;
                     mKIAA4131"
                     /inference="alignment:Splign:2.1.0"
     CDS             459..2825
                     /gene="Dgkg"
                     /gene_synonym="2900055E17Rik; 90kDa; Dagk3; E430001K23Rik;
                     mKIAA4131"
                     /EC_number="2.7.1.107"
                     /note="isoform 1 is encoded by transcript variant 1;
                     diacylglycerol kinase, gamma 90kDa; DGK-gamma; DAG kinase
                     gamma; diglyceride kinase gamma; 88 kDa diacylglycerol
                     kinase; diacylglycerol kinase, gamma 3"
                     /codon_start=1
                     /product="diacylglycerol kinase gamma isoform 1"
                     /protein_id="NP_619591.1"
                     /db_xref="CCDS:CCDS28068.1"
                     /db_xref="GeneID:110197"
                     /db_xref="MGI:MGI:105060"
                     /translation="MSEEQWVSLSSEEFDQLQKYSEYSSKKIKDVLAEFNEGGSLRQY
                     DPHKPISYDVFKLFMRAYLEVDLPQPLSTHLFLAFSQKPRQETPDHPKEGASSSEPNV
                     SDYNSDNAAKADEACAPDTESKTTKTQAPSKELEAAAPWEDPGALASSSDAPVVYLKD
                     VVCYLSLMETGRPQDKLEFMFRLYDSDENGLLDQAEMDQIVSQMLHVAQYLEWDPTEL
                     RPILKEMLQGMDYDKDGFVSLQEWINGGMTTIPLLVLLGMDDSGSKGDGRHAWTLKHF
                     KKPTYCNFCRAMLMGVGKQGLCCIYCKYTVHQRCVSKTIHGCVKTNSKAKRSGEVMQH
                     AWVEGNSSVKCDRCHKSIKCYQSVTARHCVWCRMTFHRKCELSTVCDGGELKDHILLP
                     TSICPVSGDRQGGKSDGSVAAKGELVTQYKIIPSPGTHPLLVLVNPKSGGRQGERILR
                     KFHYLLNPEQVFNLDNGGPTPGLNFFHDTPDFRVLACGGDGTVGWILDCIDKANFTKH
                     PPVAVLPLGTGNDLARCLRWGGGYEGGSLTKILKEIEQSPLVMLDRWYLEVMPREEVE
                     NGDQVPYNIMNNYFSIGVDASIAHRFHMMREKHPEKFNSRMKNKLWYFEFGTSETFAA
                     TCKKLHDHIELECDGVEVDLSNIFLEGIAILNIPSMYGGTNLWGETKKNRAVIRESRK
                     SVTDPKELKCCVQDLSDQLLEVVGLEGAMEMGQIYTGLKSAGRRLAQCSSVTIRTNKL
                     LPMQVDGEPWMQPQCTIKITHKNQAPMMMGPPQKSSFFSLRRKSRSKD"
     exon            526..602
                     /gene="Dgkg"
                     /gene_synonym="2900055E17Rik; 90kDa; Dagk3; E430001K23Rik;
                     mKIAA4131"
                     /inference="alignment:Splign:2.1.0"
     exon            603..768
                     /gene="Dgkg"
                     /gene_synonym="2900055E17Rik; 90kDa; Dagk3; E430001K23Rik;
                     mKIAA4131"
                     /inference="alignment:Splign:2.1.0"
     exon            769..822
                     /gene="Dgkg"
                     /gene_synonym="2900055E17Rik; 90kDa; Dagk3; E430001K23Rik;
                     mKIAA4131"
                     /inference="alignment:Splign:2.1.0"
     exon            823..993
                     /gene="Dgkg"
                     /gene_synonym="2900055E17Rik; 90kDa; Dagk3; E430001K23Rik;
                     mKIAA4131"
                     /inference="alignment:Splign:2.1.0"
     exon            994..1043
                     /gene="Dgkg"
                     /gene_synonym="2900055E17Rik; 90kDa; Dagk3; E430001K23Rik;
                     mKIAA4131"
                     /inference="alignment:Splign:2.1.0"
     exon            1044..1118
                     /gene="Dgkg"
                     /gene_synonym="2900055E17Rik; 90kDa; Dagk3; E430001K23Rik;
                     mKIAA4131"
                     /inference="alignment:Splign:2.1.0"
     exon            1119..1241
                     /gene="Dgkg"
                     /gene_synonym="2900055E17Rik; 90kDa; Dagk3; E430001K23Rik;
                     mKIAA4131"
                     /inference="alignment:Splign:2.1.0"
     exon            1242..1359
                     /gene="Dgkg"
                     /gene_synonym="2900055E17Rik; 90kDa; Dagk3; E430001K23Rik;
                     mKIAA4131"
                     /inference="alignment:Splign:2.1.0"
     exon            1360..1448
                     /gene="Dgkg"
                     /gene_synonym="2900055E17Rik; 90kDa; Dagk3; E430001K23Rik;
                     mKIAA4131"
                     /inference="alignment:Splign:2.1.0"
     exon            1449..1565
                     /gene="Dgkg"
                     /gene_synonym="2900055E17Rik; 90kDa; Dagk3; E430001K23Rik;
                     mKIAA4131"
                     /inference="alignment:Splign:2.1.0"
     exon            1566..1658
                     /gene="Dgkg"
                     /gene_synonym="2900055E17Rik; 90kDa; Dagk3; E430001K23Rik;
                     mKIAA4131"
                     /inference="alignment:Splign:2.1.0"
     exon            1659..1718
                     /gene="Dgkg"
                     /gene_synonym="2900055E17Rik; 90kDa; Dagk3; E430001K23Rik;
                     mKIAA4131"
                     /inference="alignment:Splign:2.1.0"
     exon            1719..1798
                     /gene="Dgkg"
                     /gene_synonym="2900055E17Rik; 90kDa; Dagk3; E430001K23Rik;
                     mKIAA4131"
                     /inference="alignment:Splign:2.1.0"
     exon            1799..1873
                     /gene="Dgkg"
                     /gene_synonym="2900055E17Rik; 90kDa; Dagk3; E430001K23Rik;
                     mKIAA4131"
                     /inference="alignment:Splign:2.1.0"
     exon            1874..1959
                     /gene="Dgkg"
                     /gene_synonym="2900055E17Rik; 90kDa; Dagk3; E430001K23Rik;
                     mKIAA4131"
                     /inference="alignment:Splign:2.1.0"
     exon            1960..2049
                     /gene="Dgkg"
                     /gene_synonym="2900055E17Rik; 90kDa; Dagk3; E430001K23Rik;
                     mKIAA4131"
                     /inference="alignment:Splign:2.1.0"
     exon            2050..2210
                     /gene="Dgkg"
                     /gene_synonym="2900055E17Rik; 90kDa; Dagk3; E430001K23Rik;
                     mKIAA4131"
                     /inference="alignment:Splign:2.1.0"
     exon            2211..2275
                     /gene="Dgkg"
                     /gene_synonym="2900055E17Rik; 90kDa; Dagk3; E430001K23Rik;
                     mKIAA4131"
                     /inference="alignment:Splign:2.1.0"
     exon            2276..2366
                     /gene="Dgkg"
                     /gene_synonym="2900055E17Rik; 90kDa; Dagk3; E430001K23Rik;
                     mKIAA4131"
                     /inference="alignment:Splign:2.1.0"
     exon            2367..2544
                     /gene="Dgkg"
                     /gene_synonym="2900055E17Rik; 90kDa; Dagk3; E430001K23Rik;
                     mKIAA4131"
                     /inference="alignment:Splign:2.1.0"
     exon            2545..2665
                     /gene="Dgkg"
                     /gene_synonym="2900055E17Rik; 90kDa; Dagk3; E430001K23Rik;
                     mKIAA4131"
                     /inference="alignment:Splign:2.1.0"
     exon            2666..2726
                     /gene="Dgkg"
                     /gene_synonym="2900055E17Rik; 90kDa; Dagk3; E430001K23Rik;
                     mKIAA4131"
                     /inference="alignment:Splign:2.1.0"
     exon            2727..5506
                     /gene="Dgkg"
                     /gene_synonym="2900055E17Rik; 90kDa; Dagk3; E430001K23Rik;
                     mKIAA4131"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5484..5489
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Dgkg"
                     /gene_synonym="2900055E17Rik; 90kDa; Dagk3; E430001K23Rik;
                     mKIAA4131"
                     /note="hexamer: AATAAA"
     polyA_site      5506
                     /gene="Dgkg"
                     /gene_synonym="2900055E17Rik; 90kDa; Dagk3; E430001K23Rik;
                     mKIAA4131"
                     /note="major polyA site"
ORIGIN      
        1 agctggactt gcgatgctgc gagggacagg gtgcagagcc gcagtgccgt agcgggtagc
       61 agaggcagcc ttcccttcca gcagcgaagg cggaagaccc cggggcgcca accctggtgg
      121 ctgcctgatg tctccgcccc agagagggct gcaccgggag atcgcccggg cgcccgcttc
      181 ggtccccttc tgtctctcgg ttcctctttc ctcccaagta agggaataag cggctaggag
      241 ggagcgcccc cggcaagcgc gcaaccaagt gttgcatggt gaggaattgc cagcatttca
      301 ggattggctg gaccgcagca ggaatgttac ctgaggagta gcggaagtcc ttcgccagct
      361 gccgagaggt gtggccctga gctgggcccc ccccccccgc ttctcgctgg tgaccagaac
      421 tccatctgtg tctcaaggca atcacactcg gctgaaagat gagcgaagaa caatgggtct
      481 ctctctcatc agaagaattt gatcaactcc agaaatactc tgaatattcc tccaaaaaga
      541 taaaagatgt attggctgag tttaatgaag gtggaagcct caggcagtat gacccacaca
      601 agcccattag ctatgatgtc ttcaagctgt tcatgagggc atacctggag gtggaccttc
      661 ctcagccact gagcacacac ctcttcctgg ccttcagcca gaagcccaga caagagacac
      721 ctgaccatcc aaaggagggg gccagcagta gtgagcccaa tgtctcagat tataattcgg
      781 ataatgctgc caaagcagat gaggcctgtg ctccagacac tgaatcaaaa acaactaaga
      841 cacaagcacc atctaaagaa ctagaggctg cagccccatg ggaagaccca ggtgctctgg
      901 cttcaagctc agatgctccc gtagtgtacc tgaaggatgt cgtgtgttac ttgtccctga
      961 tggagaccgg gcgacctcag gataagctag aattcatgtt tcgtctctat gattcggatg
     1021 aaaatggact cctggaccaa gcggagatgg atcagattgt gagccaaatg ctgcacgttg
     1081 cccagtacct ggaatgggat cccacagagc tcagacctat actgaaggag atgctgcaag
     1141 gcatggacta tgacaaggat ggcttcgtgt ctctacagga gtggatcaac gggggaatga
     1201 ccaccatccc tttgctggtc ctcctgggaa tggatgactc tggctccaag ggcgatggga
     1261 ggcatgcctg gaccctgaag cacttcaaga agcccactta ctgcaacttc tgccgcgcca
     1321 tgctgatggg tgttgggaag caaggcctgt gctgcatcta ctgtaaatat acagtccacc
     1381 aacgctgtgt atccaaaacc attcatggat gtgtgaaaac aaactccaaa gccaaaagga
     1441 gtggcgaggt gatgcagcat gcgtgggtgg aagggaactc ctccgtcaag tgtgaccggt
     1501 gccacaaaag tatcaagtgc taccagagtg tcaccgcgcg gcactgcgtg tggtgccgga
     1561 tgacgtttca ccgcaaatgt gaattatcga cagtgtgcga cggtggggaa ctcaaagacc
     1621 acattttgct gcctacctcc atatgccccg tctccggaga ccggcaagga gggaagtccg
     1681 atggcagtgt ggccgccaag ggtgaacttg taactcagta taagatcatc cctagcccgg
     1741 ggacgcatcc cctgctggtc ctggtgaacc ccaagagtgg aggaagacaa ggagaaagaa
     1801 ttcttcggaa atttcactac ctgctcaacc ccgaacaagt tttcaacctg gacaatgggg
     1861 gacctacacc aggattgaac ttctttcatg ataccccaga cttccgtgtt cttgcctgtg
     1921 gcggagatgg gaccgttggc tggattttgg attgcattga taaggctaac ttcacaaagc
     1981 acccaccggt ggctgtcctg cctcttggaa cagggaatga cctcgcacga tgcctccgct
     2041 ggggaggagg ttacgaaggg ggcagcttga ccaaaatcct gaaggaaatt gaacagagcc
     2101 ccttggtgat gctggaccgt tggtacctag aggtcatgcc cagggaagag gtggagaatg
     2161 gagaccaagt cccatacaac atcatgaaca actatttctc cattggtgtg gatgcttcaa
     2221 ttgcacacag attccatatg atgagagaga aacaccctga aaaattcaac agcaggatga
     2281 agaacaagct gtggtatttc gaatttggta cctcggaaac ctttgcagcc acctgcaaga
     2341 aactccatga ccacatagag ctggagtgtg acggagttga ggtggatctg agcaacatct
     2401 tcctggaagg catcgccatt cttaatattc ccagcatgta cggaggcacc aatctctggg
     2461 gagaaaccaa gaagaaccgg gctgtgatcc gggaaagcag gaagagcgtc acagacccaa
     2521 aggagctgaa atgctgtgtc caagacctca gcgatcagct ccttgaagtg gtgggtctag
     2581 agggagccat ggagatggga cagatctaca ctggcctgaa gagtgcgggc aggagactgg
     2641 cccagtgctc ctctgtcacc attaggacta acaagcttct gccgatgcaa gtagacggag
     2701 agccctggat gcagccacaa tgcacgatta aaatcactca caaaaaccag gcacctatga
     2761 tgatggggcc tccccagaag agcagctttt tttctctgag gaggaaaagc cgttcaaaag
     2821 actaaacaat atgccaaaca ccagctctac tgagaaagga aagaagaatc tacacacaca
     2881 cacacacaca cacacacaca cacacacaca cacacctgta accagaggaa gccaagccac
     2941 cttccagagg aaagtgcaat cctgccatgc agtctacctg ttttgaaaat ggatccactc
     3001 ttaacagagc caatacccat gaaatattcc aaatggactc agggcccacg aagatgggtt
     3061 ggctcatgca gcaactttca cattcccaca ggctttgggt agactttgag cctgcaggag
     3121 aaatctccct ttttctgtgc cacactcctg taaggctcca ggttgtaggt ttcctgccta
     3181 cagcaagatc ggatgtggtc aagggaaaga gctccaaccc agaaaccttg cacaaaagtc
     3241 cttctgtata aaaacaaaac agcccacagc tctgcaagca gaagccttgg cagggctcgg
     3301 cgagcacagg atggttgctt tgctgtcctt caagtaacag ctcccccctt aacttgcagg
     3361 ggaaagccaa gaagctgtgg aaagccgttt ccattcttgg ttccctctgc tgtccatggg
     3421 tacttgttcg cttcctgaag catctcttgg tggctgtttt gcttagagag caaacaaggc
     3481 tgcccgggca gcgtgcttta gatgtggtat ttattttcat agttcctatg aacacttggg
     3541 aggaagagct gagaaagtgg actttatttt tcaaatttga tgtcataata ttgtgtaaaa
     3601 aggaaagaaa cagaaaaaaa aaaaaaaaaa cactcccagt attccccact cctcactacc
     3661 atacaagcca aagtgtgtca ctttgaatcc caagccctgg tggcagagac gatgggggta
     3721 tgggtttggg gggactttgc tgggaaaacc aggagactgt tacgggactc cctgtttgca
     3781 catctcactc tcacagtgtg gcagaggggc cttctgatgg tcttctctac atacctatgt
     3841 agcgtatttg tttatatata atatataaat atttatttac tgctggactt ttcctgatta
     3901 gaaataaaca tagtgtggga acaggacatg ggaaagaaaa aagaagaagg cccttactct
     3961 tccactgtcg tttgcttgta gagacacatt tctctggctg gtttcaaggt ttatgagaat
     4021 tatctacatc cggggagcaa ctatgaacac gtgctgttca agcctcattc cccccccccc
     4081 attggttgat aaggaaactg agttgtggaa aagttaaaga cttctccatt ttattgtgga
     4141 taaggaggtt tgactgtaaa tgttactaag aaggtcacta acaaacagaa gaacctgcat
     4201 ctggggaaag ggttatttct tgtcactgag gattggtcga tgttggatct aggttcccag
     4261 caaggaacca tcttatagcc tgtgtgtgga tggagcaagc ccacacaaga aaatgggagg
     4321 tggagaattg agctaacttc caagtgcttt atggcttgtc ctacatggag agaagttggc
     4381 ctgatgttaa aggcaccaga cagatcaatt gattgaacta ctatgtcatc tcatcatgtc
     4441 accgatcttc ttgctttgga taccttcctg ggtacatctg tgacttctgt aagatgttgc
     4501 caaccagaac agaagagttt tggccctgct cagtgggctt cagtcagctg gtgccagcat
     4561 cttcctcctc tctggagggc aactctatac agcatcactg gtagaaagca acagttgcct
     4621 caggcccctg gctcccctgg accttcattt ctgtctcaaa tttcttaaga ggaaatccag
     4681 gcccagtttg acatcactcc actgagctgc ctccagtctt gccatagcca aggaagggaa
     4741 tatgaagaat ctgtacaagt tgagcccacc tcggaaggaa gcactctcaa ctagaatcca
     4801 gggctgagac ttggaaccct cctgctcagc aaacatgctt ctactgagca agggagacac
     4861 caggccacat aaagagcata ctggtgggat gcctagagat gtgaccagcc agctccggag
     4921 taatagcaag cactactttg gaagacaatt gattcagaaa ctgaggcaga ttcaacttca
     4981 aggtcacgga ttctaaaaat ttcacagaag tgtttgtata tgtttcagct ctgaccccca
     5041 cgaggtcaca gatgttgaga caatactatc agtaggtaaa acggactcac gagtctctcg
     5101 atggggccct gcagaggtta aatgtttctt gagaaacaca gcccagttct tttcaaaggc
     5161 acagagtata aaatgtggca ttgcacttct aatttgttgt tgtttaatct taccttacaa
     5221 atcatctttt aaacaccatg gctgtggttt cttattgtgt agtgcatcat ccaagtgact
     5281 cccacaccaa gctctacggc tagccagcaa agtattatta tttccacctt gcagaggaga
     5341 gggggggggg cttactggtg tttagtagct tcttcaagct ccgtggtcaa gggagagcct
     5401 agtctctcct ctcttctcct gctcatattc ttctcacgct gcagacttgt tctcacctgc
     5461 cttcctgctt ccgccccact agcaataaaa acaatgaaac cggaaaaaaa aaaaaaaaaa
     5521 a
//
