LOCUS       NM_177192               9833 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus DENN domain containing 5B (Dennd5b), mRNA.
ACCESSION   NM_177192
VERSION     NM_177192.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 9833)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 9833)
  AUTHORS   Mobilia,M., Whitus,C., Karakashian,A., Lu,H.S., Daugherty,A. and
            Gordon,S.M.
  TITLE     Dennd5b-Deficient Mice are Resistant to PCSK9-Induced
            Hypercholesterolemia and Diet-Induced Hepatic Steatosis
  JOURNAL   J Lipid Res 63 (12), 100296 (2022)
   PUBMED   36243100
  REMARK    GeneRIF: Dennd5b-Deficient Mice are Resistant to PCSK9-Induced
            Hypercholesterolemia and Diet-Induced Hepatic Steatosis.
REFERENCE   3  (bases 1 to 9833)
  AUTHORS   Iwaki,A., Moriwaki,K., Sobajima,T., Taniguchi,M., Yoshimura,S.I.,
            Kunii,M., Kanda,S., Kamada,Y., Miyoshi,E. and Harada,A.
  TITLE     Loss of Rab6a in the small intestine causes lipid accumulation and
            epithelial cell death from lactation
  JOURNAL   FASEB J 34 (7), 9450-9465 (2020)
   PUBMED   32496646
REFERENCE   4  (bases 1 to 9833)
  AUTHORS   Gordon,S.M., Neufeld,E.B., Yang,Z., Pryor,M., Freeman,L.A., Fan,X.,
            Kullo,I.J., Biesecker,L.G. and Remaley,A.T.
  TITLE     DENND5B Regulates Intestinal Triglyceride Absorption and Body Mass
  JOURNAL   Sci Rep 9 (1), 3597 (2019)
   PUBMED   30837651
  REMARK    GeneRIF: DENND5B Regulates Intestinal Triglyceride Absorption and
            Body Mass.
            Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BB656426.1, AK135015.1, BC132535.1, CN537548.1, CV558497.1 and
            AC140327.3.
            
            On Apr 20, 2007 this sequence version replaced NM_177192.2.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN01164139
                              [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-116               BB656426.1         1-116
            117-1848            AK135015.1         2-1733
            1849-3174           BC132535.1         1554-2879
            3175-3325           AK135015.1         3058-3208
            3326-3627           CN537548.1         323-624
            3628-4179           CV558497.1         213-764
            4180-9833           AC140327.3         40045-45698
FEATURES             Location/Qualifiers
     source          1..9833
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 78.71 cM"
     gene            1..9833
                     /gene="Dennd5b"
                     /gene_synonym="9330160C06Rik; D030011O10Rik; Gm17524"
                     /note="DENN domain containing 5B"
                     /db_xref="GeneID:320560"
                     /db_xref="MGI:MGI:2444273"
     exon            1..498
                     /gene="Dennd5b"
                     /gene_synonym="9330160C06Rik; D030011O10Rik; Gm17524"
                     /inference="alignment:Splign:2.1.0"
     CDS             372..4196
                     /gene="Dennd5b"
                     /gene_synonym="9330160C06Rik; D030011O10Rik; Gm17524"
                     /note="RAB6IP1-like protein; DENN/MADD domain containing
                     5B"
                     /codon_start=1
                     /product="DENN domain-containing protein 5B"
                     /protein_id="NP_796166.2"
                     /db_xref="CCDS:CCDS20714.2"
                     /db_xref="GeneID:320560"
                     /db_xref="MGI:MGI:2444273"
                     /translation="MSGSSAAPGPGSGSSPAACRFAHYFVLCGIDADSGLEPDELAGE
                     NFDQSPLRRTFKSKVLAHYPQNIEWNPFDQDAVNMLCMPKGLSFRTQADNKEPQFHSF
                     IITREDGSRTYGFVLTFYEEVTSKQICTAMQTLYQMHNAEQYSSVYASSSCSMDSLAS
                     SIDEGDATSLLKLQRYNSYDINRDTLYVSKSICLITPLPFMQACKKFLFQLHKAVTSQ
                     QPPPLPLESYIHNILYEVPLPPPGRSLKFYGVYEPVICQRPGPNELPLSDYPLREACE
                     LLGLENLVQVFTCVLLEMQTLLYSQDYQRLMTVAEGITTLLFPFQWQHVYVPILPASL
                     LHFLDAPVPYLMGLQSKEGTDRSKLELPQEANLCFVDIDNHFIELPEEFPQFPNKVDF
                     IQELSEVLLQFGIPPEGSLHSSESATKLKNMVLKDLANDKKNGNVPNNSVSVYELLKG
                     SETIARLQALAKRTGVTMEKIDLPASLSEKEKDLKLQCEEADLRDSQLNVQLREVFAN
                     RFTQMFADYEAFVIQTAQDMESWLTNREQMQNFDKASFLSDQPEPYLPFLSRFIETQM
                     FATFIDNKIMSQWEEKDPLLRVFDSRIEKIRLYNVRAPTLRTSIYQKCSSLKEAAQSI
                     EQRLMKMDHTAIHPHLLDMKIGQGKYEQGFFPKLQSDVLATGPANNNRWVSRSATAQR
                     RKERLRQSSEHIGLDSDLREKYMQEARSLGKNLRQPKLSDLSPAVIAQTNWKFVEGLL
                     KECRMKTKRMLVEKMGHEAVELGHGEANITGLEENTLIASLCDLLERIWSHGLLVKQG
                     KSALWSHLLQFQDREEKQEHLTDSPVALGPERRKSDSGVMLPTLRVSLIQDMRHIQNM
                     TEIKTDVGRARAWIRLSLEKKLLSQHLKQLLSNQPLTKKLYKRYAFLRCEEEREQFLY
                     HLLSLNAVDYFCFTSVFTTIMIPYRSVIIPIKKLSNAIITSNPWICVSGELGDTGVMQ
                     IPKNLLEMTFECQNLGKLTTVQIGHDNSGLLAKWLVDCVMVRNEITGHTYRFPCGRWL
                     GKGVDDGSLERILIGELMTSASDEDLGKQCRTPPQQKSPTTTRRLSITSLTGKPAKPN
                     AGQIQEGIGEAVNNIVKHFHKPEKERGSLTVLLCGENGLVAALEQVFHHGFKSARIFH
                     KNVFIWDFVEKAVAYFETTDQILDNEGDVLIQKPSSKTFCHYVNAINTAPRNIGKDGK
                     FQILVCLGTRDHLLPQWIPLLAECPAITRMYEENALLRDHMTVNSLIRILQTIQDFTI
                     VLEGSLIKGVDV"
     exon            499..608
                     /gene="Dennd5b"
                     /gene_synonym="9330160C06Rik; D030011O10Rik; Gm17524"
                     /inference="alignment:Splign:2.1.0"
     exon            609..1275
                     /gene="Dennd5b"
                     /gene_synonym="9330160C06Rik; D030011O10Rik; Gm17524"
                     /inference="alignment:Splign:2.1.0"
     exon            1276..1463
                     /gene="Dennd5b"
                     /gene_synonym="9330160C06Rik; D030011O10Rik; Gm17524"
                     /inference="alignment:Splign:2.1.0"
     exon            1464..2000
                     /gene="Dennd5b"
                     /gene_synonym="9330160C06Rik; D030011O10Rik; Gm17524"
                     /inference="alignment:Splign:2.1.0"
     exon            2001..2232
                     /gene="Dennd5b"
                     /gene_synonym="9330160C06Rik; D030011O10Rik; Gm17524"
                     /inference="alignment:Splign:2.1.0"
     exon            2233..2383
                     /gene="Dennd5b"
                     /gene_synonym="9330160C06Rik; D030011O10Rik; Gm17524"
                     /inference="alignment:Splign:2.1.0"
     exon            2384..2477
                     /gene="Dennd5b"
                     /gene_synonym="9330160C06Rik; D030011O10Rik; Gm17524"
                     /inference="alignment:Splign:2.1.0"
     exon            2478..2609
                     /gene="Dennd5b"
                     /gene_synonym="9330160C06Rik; D030011O10Rik; Gm17524"
                     /inference="alignment:Splign:2.1.0"
     exon            2610..2762
                     /gene="Dennd5b"
                     /gene_synonym="9330160C06Rik; D030011O10Rik; Gm17524"
                     /inference="alignment:Splign:2.1.0"
     exon            2763..2841
                     /gene="Dennd5b"
                     /gene_synonym="9330160C06Rik; D030011O10Rik; Gm17524"
                     /inference="alignment:Splign:2.1.0"
     exon            2842..2923
                     /gene="Dennd5b"
                     /gene_synonym="9330160C06Rik; D030011O10Rik; Gm17524"
                     /inference="alignment:Splign:2.1.0"
     exon            2924..3052
                     /gene="Dennd5b"
                     /gene_synonym="9330160C06Rik; D030011O10Rik; Gm17524"
                     /inference="alignment:Splign:2.1.0"
     exon            3053..3174
                     /gene="Dennd5b"
                     /gene_synonym="9330160C06Rik; D030011O10Rik; Gm17524"
                     /inference="alignment:Splign:2.1.0"
     exon            3175..3320
                     /gene="Dennd5b"
                     /gene_synonym="9330160C06Rik; D030011O10Rik; Gm17524"
                     /inference="alignment:Splign:2.1.0"
     exon            3321..3439
                     /gene="Dennd5b"
                     /gene_synonym="9330160C06Rik; D030011O10Rik; Gm17524"
                     /inference="alignment:Splign:2.1.0"
     exon            3440..3627
                     /gene="Dennd5b"
                     /gene_synonym="9330160C06Rik; D030011O10Rik; Gm17524"
                     /inference="alignment:Splign:2.1.0"
     exon            3628..3710
                     /gene="Dennd5b"
                     /gene_synonym="9330160C06Rik; D030011O10Rik; Gm17524"
                     /inference="alignment:Splign:2.1.0"
     exon            3711..3837
                     /gene="Dennd5b"
                     /gene_synonym="9330160C06Rik; D030011O10Rik; Gm17524"
                     /inference="alignment:Splign:2.1.0"
     exon            3838..4012
                     /gene="Dennd5b"
                     /gene_synonym="9330160C06Rik; D030011O10Rik; Gm17524"
                     /inference="alignment:Splign:2.1.0"
     exon            4013..9833
                     /gene="Dennd5b"
                     /gene_synonym="9330160C06Rik; D030011O10Rik; Gm17524"
                     /inference="alignment:Splign:2.1.0"
     regulatory      9811..9816
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Dennd5b"
                     /gene_synonym="9330160C06Rik; D030011O10Rik; Gm17524"
                     /note="hexamer: AATAAA"
     polyA_site      9831
                     /gene="Dennd5b"
                     /gene_synonym="9330160C06Rik; D030011O10Rik; Gm17524"
                     /note="major polyA site"
ORIGIN      
        1 agttgacccg cgggcgccag acgctgcgct ccagcgggcg cagccgcggc ggcgcgggcc
       61 tccctagctg acactccccc tgcgcgcccc tcccccgccg cggcggaatc ccgcccgccc
      121 tccggtccgc gcgcgagccc gaggccgctt cctcggtacc agcgtctaga aggatcccgg
      181 ccgcggcgat tgcgcggcca tgggcgcgcc gggctcgtcc tagggtcgcg gcggagaccg
      241 cagtcggagc gccgcggtgg cctcctccgc gagggaagcc tgcgacgctt ctcagcgagg
      301 cttctcatcg gttcacgccg gagagcctcc tccgcgaacc ccagcgacgg tcgcaccggc
      361 agcgcggcgg gatgagcggt agcagcgcgg cgccgggccc gggctcgggg tcctccccgg
      421 ccgcctgtcg cttcgcgcac tacttcgtgc tgtgcgggat cgatgcggac agcgggctgg
      481 agcccgacga gctggcgggt gaaaattttg atcagagtcc tctgagaaga acattcaaat
      541 ccaaagttct ggcccactat cctcaaaaca tagaatggaa cccttttgat caagatgcag
      601 tgaacatgct gtgcatgccc aaagggctgt ctttcagaac acaagctgac aataaagagc
      661 ctcagttcca ctcatttata attacccggg aagatggttc tcgcacctat ggttttgttc
      721 tcactttcta tgaagaagtt acaagtaagc aaatctgtac agccatgcag acactgtacc
      781 agatgcataa tgctgagcag tacagcagtg tgtacgcttc atcctcttgc agtatggact
      841 cactggcaag tagtattgac gagggagatg caacctctct tttgaaactc cagcgataca
      901 actcttatga catcaacaga gacaccttgt atgtttcaaa aagtatctgc ttgatcacac
      961 ctctgccttt catgcaagcc tgcaagaaat tcctcttcca acttcacaag gcagttacct
     1021 cacagcagcc accacccttg ccgcttgaga gctatatcca caatattctc tacgaggtgc
     1081 cccttccgcc tcctgggagg tcactgaaat tttatggtgt ttatgaacct gtcatctgcc
     1141 agaggcctgg gcccaatgaa ctccctcttt ctgactaccc tcttcgagag gcctgtgagc
     1201 tcctgggatt agagaaccta gtgcaagtgt tcacctgtgt tcttttagag atgcagaccc
     1261 ttctctactc acaagattat cagcgcctga tgacagtggc agaaggcatt accacactct
     1321 tgttcccttt tcaatggcag catgtttatg tacccatcct ccctgcctct ctgctacatt
     1381 ttcttgatgc ccctgtccct tatctgatgg gtcttcagtc aaaagaagga actgaccggt
     1441 ctaaattaga acttcctcaa gaggctaatt tgtgcttcgt ggatattgac aaccatttta
     1501 ttgagttgcc tgaagaattt ccacagttcc ccaataaagt ggattttatc caagagttgt
     1561 ctgaagttct tctccaattt gggattcctc ctgagggcag cctacattct agtgagagtg
     1621 ccaccaaact gaagaatatg gttctgaaag atttggctaa tgacaaaaag aatggaaatg
     1681 tccccaacaa cagcgtcagc gtgtatgagc tactgaaggg cagtgagacc atagcccgcc
     1741 tccaggctct tgccaagagg actggggtga ccatggaaaa aattgacctt ccagcttctc
     1801 tgagtgaaaa agaaaaggat ttaaaattgc agtgtgaaga ggccgacttg agggactccc
     1861 agctcaatgt acagctgcga gaggtctttg ccaaccgctt tacacagatg tttgccgatt
     1921 acgaagcatt tgtgattcag actgcccagg acatggagtc ctggctgacc aaccgggaac
     1981 agatgcagaa ctttgacaaa gcttcttttc tctctgacca gcctgagcct tacctgccat
     2041 ttctttcacg cttcattgaa acacagatgt ttgccacctt tattgataat aagatcatgt
     2101 ctcaatggga agagaaagac cctctgcttc gggtctttga ttctcggatt gagaagatca
     2161 gattgtataa tgtaagggca cccaccctgc ggacatctat atatcagaaa tgcagcagtt
     2221 taaaagaagc agcccagtca attgaacaaa gattgatgaa aatggatcac actgcaatcc
     2281 acccacatct acttgatatg aaaattggtc aaggcaaata tgagcaaggg ttctttccaa
     2341 agttacagtc cgatgtcttg gcaacaggac cagccaataa caatcgctgg gtgagtcgaa
     2401 gtgccacagc acagcgcagg aaagagcgcc ttcgccagag ctctgaacac attgggctgg
     2461 acagtgactt acgggagaaa tatatgcaag aggcacgaag tttaggaaaa aacctgaggc
     2521 aaccaaaact gtcagatctt tcacctgctg tgattgcaca aaccaactgg aaatttgtag
     2581 aaggtttatt aaaagaatgc agaatgaaga caaaacgcat gttggtagag aagatgggac
     2641 atgaagcagt agaactgggc catggagaag caaacattac tggcttggaa gaaaacacct
     2701 tgatcgccag cctgtgtgac ctactggaga ggatatggag ccacggctta ctggtcaagc
     2761 aggggaagtc tgccttgtgg tcacatttgc tccagtttca ggatagagaa gagaaacaag
     2821 agcacctcac agactcgcca gttgcccttg gaccagaaag aagaaaatct gactcaggag
     2881 ttatgttacc aacactcaga gtctctctta ttcaagacat gaggcatatt cagaacatga
     2941 ctgagatcaa gactgacgtt ggacgggcgc gggcgtggat aaggttgtcc ctggaaaaga
     3001 agctcttgtc gcagcacctc aagcagctgc tctctaacca gccactgacc aagaagcttt
     3061 ataagcgcta tgcttttctc cgttgtgaag aagaaagaga acagtttctt taccatctgc
     3121 tttccctcaa cgctgtggac tacttctgct ttaccagtgt gttcaccact atcatgattc
     3181 cttatagatc agtgatcatt ccaattaaaa agctgagcaa tgcaatcatt acctcgaacc
     3241 cgtggatctg tgtttcagga gagctgggag acaccggagt aatgcagatt ccaaagaact
     3301 tgcttgagat gacttttgag tgccagaacc tgggaaagct gactacagtt cagattggcc
     3361 atgataactc cggactgtta gctaaatggc tagtggattg tgtcatggtc agaaatgaaa
     3421 tcacaggaca tacatacaga ttcccttgtg ggcggtggct ggggaaaggc gtggatgacg
     3481 gcagcctgga gagaattctt attggagaat tgatgacatc agcttcagat gaagacctgg
     3541 gaaagcagtg tcggactcca ccacagcaga aatctcccac gacaaccagg agactgagta
     3601 ttacctcact aacgggaaag cctgccaaac ccaatgctgg acagatccaa gaaggaattg
     3661 gagaagctgt gaacaatatt gtgaagcatt ttcacaaacc tgagaaagag agaggaagcc
     3721 tcacagtgct gctgtgcgga gaaaatggcc tggttgctgc acttgaacaa gttttccatc
     3781 atgggttcaa atctgcccgc atctttcaca agaatgtctt catctgggac ttcgtagaga
     3841 aagcagtggc ttattttgaa accactgacc agattttaga caatgaaggt gatgtgctca
     3901 ttcagaaacc atcaagcaaa accttctgcc actacgtgaa tgctattaac actgcaccca
     3961 ggaacattgg gaaggacggc aaattccaga ttctagtttg cctgggaaca agggatcacc
     4021 tgcttccaca gtggattcca ttgctagcag aatgtcctgc catcacccga atgtatgaag
     4081 agaatgcact gcttcgagac cacatgactg tcaactccct tatccgaatt cttcagacca
     4141 ttcaggattt caccatagtc ttggaaggat cactaatcaa aggagtggat gtgtaaagca
     4201 gccggcagaa actcttcatc tacccctggc tcctgaagct tccgtaacta tggggaccta
     4261 tctggaccgg tctgaccata gtgagcactg ccggggcagt gcactggaag ccccagtttg
     4321 aacagtctcc actctgcaga caaggcaaag tgctgtattg tagttcattt gaacctgaaa
     4381 tttagtataa aatagagtat tttcatgtgt tagaagtgtg taaatatgct atctttaaga
     4441 aattatatta ctctaataag atacttttct tagattgaat atccctgtga cttaaaataa
     4501 gtagtttaaa aatgttgggg gtggggaaag cggtgctagt caggaagaag ccagtaaatg
     4561 tgtacatagt gcaacccagg aaggcttctt tttccctcca ggtctcacaa aggaaccaga
     4621 atgctttgtc ctgaagcagc catccctcct ggagtcccat cctgtgtgtg gtgaatgtat
     4681 acagctttac atagtgtaca gcagtcctca ttgtaccttt taagttataa accatttaat
     4741 acatttgaat tatgagtaat ttttttagtt tttgggaacg tttttcattg gcataaggaa
     4801 aagataatta aagtatttta aatatcagac cccagcaagg catagtggcg cactcccagc
     4861 actagggagg caggggcagg tgcatctgag ttgcagacca gacagagcta catagcaaga
     4921 ccctatctca acagagagag agagagagag agagagagag agagagagag agagagagag
     4981 cgcaaatacc agatcccaag agcttggcta attggaaagc aaacacaaga agccctgaga
     5041 agcatgggac tttaacttct ttacttttga aagattagcc tggaggcttc gttcttggaa
     5101 tttttattac tgttctttga tagggctttt gagataatga attttagtat caatcatata
     5161 gccataactg taagaaacag tgtgactttt aacttggcca tctaaactct ttaagtggag
     5221 ctaaactacc agcccagtct ttgttaggtt ccagccactc cctctgtccg ccccatcccc
     5281 cctctcagga aataaaagga atgtgggaga aggaggaggt ctcagtgtga tttggaatgc
     5341 ttttgtgaag gtatttgttg accatgataa tgcaaataac agaagctgag agaaagaatg
     5401 aagcctttct gggtgtttca gggaaatgta aagcaattgt cccagagaag ttaaaagcca
     5461 ctgtggcaga ctgaggagtg aatttgactc aagagacaat ttaggaactc ctgaaacctt
     5521 tctagtttga tagcttattt atttttttgt taagcaaatg ttagcaacta cataaatctt
     5581 tatcttttgg tgagtaagtt tcggaactct aattaggcac cgataccttg ttagtagcaa
     5641 aattgcctcg gcagagctcc aggttttatt ccctgttgta gctgaaaacc caagccatgg
     5701 cctctcagga tccgtgtgca atctcagggc cctgggctct tgccagcagt gctgttttcc
     5761 tgtttactgg aggaagggac taatagatca agtacctcat gccctttatc agaaactctg
     5821 aagaaaaggg ttgctgagga tacatttaca cacccatgga aagaaagggc ttagaacatg
     5881 tctctagatg acctgtgtaa cccagtggtt tgtttactta gaataagggt gtttatagta
     5941 gaatgagagt attctagaga ccaatctact tactatagga aacatccaca aattaagata
     6001 cagtccatcc cagggtttta ttgctgtctt ttcccatggg gccatcctga tgctgagcgc
     6061 ttggtggact tttaagtcag tgttccacag ttgagtccca acagcaagta cagcctcttc
     6121 attttatagg tgaaaatagg acacttcaaa tcaaagactt tgtattcttg ccctctcccc
     6181 cttgacaaca caagggttag aatttatgct ttttaccaca cccgagagca tgaaaccaac
     6241 ctcggagaca ttcttactca ggatcatttc ttctgttgaa tcttcagtca actgtacaga
     6301 taggaagcta tgtttctgtg atgcagaata ataaggactg aagcttgcct tgccgcgtta
     6361 gattgttttg ttgttgtttg tgaaacagga tctcactgta tatccctggc tggccctgga
     6421 acttcatttg tagaccaggc tcacctggag agatctacct cctaagtgag ggattcatgt
     6481 gagagccctg cctaccaaac tgttcttaat ctcttaggca ttacatctgt ggttaaaaaa
     6541 tgggagcaga gttgcattcc agcttaagtt taaaactgtt acttaaagta gtaccaaaaa
     6601 aacaaaaaat tacctataaa gttttttgtt ccacatgatg tcctttggat gagctaatgg
     6661 ctagccttat gccttgctca gacagctggg cctcgtggga gctgcttaac tgacccatag
     6721 cccattcctt tgaatttccc actggcgata gatcttagcc gtacaggata aatttaatat
     6781 gtagaaacac tgtaaagacc ttagggtgtg ataaaaaaga aaaatgtttc cactgaattt
     6841 ggggttaccc attgcaaatg ataaagaagt aaggcttctt atgtgaccta taacaaactg
     6901 aatcaatatg ggaaatgcat cacaatggta acattgctca aaacagatgc atataatcgt
     6961 acaagctgac ttctgtaagg accatacaac aggcatcctt cgtgctgtgc tatttaaaaa
     7021 caaacagaca aaaaacttag tacaaagctt tagaatcacc gcatagaaaa tgaaaatcaa
     7081 aactttattt gcgtgtgtgc aaataaattt aaagcaaata cctgggacca agattaatat
     7141 cctacgtagt aactaaagtt aaattggcaa ggagaggtag ctaagcagtt aagagcactg
     7201 gctgctcttg cagaagaccc aggttcattg ccagcaccca catggtacct cacacccacc
     7261 tattactaca gttccagagg atcggatgaa ctcttctaac caccttgggc acccagcata
     7321 gtgaacatac attcgtgtag gcaaaactct catgaaataa aacaaatctt tttttaaata
     7381 tcttattaaa tgtgcagtgg ctggggatgt agctcagtgg tagaatgcct gtgtagtaaa
     7441 tacaaaacct tgggttctgt cctcagcaca aataaaattg ccaaattttt aacttcttca
     7501 aaagcttgtt ctccaagtct ttgttttgag taataaaatc tctaatctta accttcatgt
     7561 cacatttctg gtggccttac agtggcttgc atattatatg tgaaaagctc tcaatgcttt
     7621 aagaaggaag tactttgggc tggtgagatg gctcagtggg taagagcacc cgactgctct
     7681 tccaaaggtc caaagttcaa atcccagcaa ccacatggtg gctcacaacc atccgtaacg
     7741 agatctgact ccctcttctg gaatgtctga agacagctac aatgtactta catataataa
     7801 ataaataaat ctttaaaaaa aaaaaaaaaa aaaaaaaaaa aagaaggaag tactttagta
     7861 cttcacaatg actgagcttc tccatgtgag gtagggttgt gagtcagaaa gcaggctgcc
     7921 aggaacaagt gaagacccct gacttgaccc tgtttcccct gggaatgaaa atctgatgga
     7981 ggaaacctaa aatttgcaac tgttgaattt catctaaaat tcattttaaa tgttcatatt
     8041 tattgtacct tttctagctc tgtaggattt atttaacatg acttttaaaa tttttatttt
     8101 aatgaacttc tatagcactg tatgagtaat aaacatttgt ttctacttcc ttttctgaca
     8161 gtaagcacat gtataagtgt aatgaaaaac agattaaggc tatacatagg actttgtgtc
     8221 tgacatgtgt caatatctct aaaataggaa gtagtagaca aggccaggga aatatttgac
     8281 agtattggga agagagttct ttacaatgtg aaatatcttc taagaataat ggcttttcaa
     8341 tagagtattc atttaggaaa ttgttttttc tctgaagttt acagaagcta gtctaccctt
     8401 ttcatggtgt tgaaagggtg ttctaaactt atatatttca gtattagcac atctttattg
     8461 attgacaaca gagtactcta ctgctttgat agagtaaatg gtatctctaa gcctctgtgt
     8521 cttttgtttg gtttagtttt gctttttttt tttttttttt ttttaagagt cctcaaagag
     8581 gccttggctg tcctagaatt cactctatag accaaccatg ctggccttga actcacagac
     8641 atccacctgc ctttgcctcc caagtgctgg aatcaaaggc atacaccacc acacctggca
     8701 agcatcagtg tctttagaaa tctttgtttc tttctctctc ctcttttaaa gatttattta
     8761 ttttttatgt gtacatcatt ctggctgcat gtatgcctgc agagcagaag cttattagag
     8821 atgttattac atatctcatt acagatggtt gtgagccgcc atgtggttgc tgggaattga
     8881 actcaggacc tctggatgag cagtcagtca gtgctcttaa ccgctgagcc atctctccag
     8941 cctgaaatct ttgtttctta tgtagctatt tttttttcaa tatcatttag aataactggg
     9001 agactttctg tctcttttaa cttatgtccc ttttttaaaa aaatacatgt acaattttgc
     9061 tcaatccaat ggaccgttga gctttgtaaa gaagtttgct tttgcggtat gataaaaggc
     9121 atccaaggag gggctggagt gagttcagtg ttagatgtgc ttaacatact tacacaaggc
     9181 cctgagcagc actccagcaa aagaaaataa actcaaggat gattatagcc gccctccccc
     9241 ccaagtctga tgtctctctc cctctctcaa ggataagatc aaaattgatt tcagaaagac
     9301 acattgaggt gttcatattt atatcagact gaagaaaagt tcatcaaata aacttccccc
     9361 tcttggaagg gttctgtcat gtccttagtg atttaggaag tagccatgct tgcttggtcc
     9421 aattacttgt gtgttggatc caagatgtat tttaaacaaa tattggcata gatagtaagg
     9481 agtttctgtt gtcagtcaaa tgaggatata aaacatagaa aaaaaaatct tatgctacac
     9541 ttgagcctca tataaagata gcctgtgttt tgttgttgtt gttgttggtt ttgtttttaa
     9601 ttactatttc tgcatttaaa ttatacactg ttttcctttg tattattaac aatgtatgtc
     9661 agaactggag ttttctcccc tcccccatct gaacataata taaaatctga aaagtattgt
     9721 gacaagcact ttaacatatc agacaaactg acatgggttt tcaggttttg gagtacattt
     9781 aaatatgact tttcatgctt tgttctttac aataaaactg tggggttgat act
//
