LOCUS       NM_024179               2407 bp    mRNA    linear   ROD 30-JUL-2024
DEFINITION  Mus musculus DAP3 binding cell death enhancer 1 (Dele1), mRNA.
ACCESSION   NM_024179
VERSION     NM_024179.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2407)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2407)
  AUTHORS   Huynh,H., Zhu,S., Lee,S., Bao,Y., Pang,J., Nguyen,A., Gu,Y.,
            Chen,C., Ouyang,K., Evans,S.M. and Fang,X.
  TITLE     DELE1 is protective for mitochondrial cardiomyopathy
  JOURNAL   J Mol Cell Cardiol 175, 44-48 (2023)
   PUBMED   36539111
REFERENCE   3  (bases 1 to 2407)
  AUTHORS   Bay,D.H., Busch,A., Lisdat,F., Iida,K., Ikebukuro,K., Nagasawa,K.,
            Karube,I. and Yoshida,W.
  TITLE     Identification of G-quadruplex structures that possess
            transcriptional regulating functions in the Dele and Cdc6 CpG
            islands
  JOURNAL   BMC Mol Biol 18 (1), 17 (2017)
   PUBMED   28655335
  REMARK    GeneRIF: Dele and Cdc6 G-quadruplex formation is significant in the
            transcriptional regulation. Dele and Cdc6 G-quadruplex DNA alone
            possess enhancer and promotor function.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2407)
  AUTHORS   Harada,T., Iwai,A. and Miyazaki,T.
  TITLE     Identification of DELE, a novel DAP3-binding protein which is
            crucial for death receptor-mediated apoptosis induction
  JOURNAL   Apoptosis 15 (10), 1247-1255 (2010)
   PUBMED   20563667
  REMARK    GeneRIF: Functionally characterizes the human homolog as a
            DAP3-binding protein involved in apoptosis mediated by death
            receptors.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY193394.1, AK002437.1, AK009400.1 and AU257559.1.
            
            On Jul 22, 2009 this sequence version replaced NM_024179.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK002437.1, AK171837.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: PMID: 20563667; reported by
                                                  MitoCarta
            RefSeq Select criteria             :: based on single
                                                  protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-49                BY193394.1         2-50
            50-1881             AK002437.1         40-1871
            1882-2401           AK009400.1         894-1413
            2402-2407           AU257559.1         119-124
FEATURES             Location/Qualifiers
     source          1..2407
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="18"
                     /map="18 20.15 cM"
     gene            1..2407
                     /gene="Dele1"
                     /gene_synonym="0610009O20Rik; 2700004E22Rik; Dele;
                     DELE1(L); Kiaa0141"
                     /note="DAP3 binding cell death enhancer 1"
                     /db_xref="GeneID:66839"
                     /db_xref="MGI:MGI:1914089"
     exon            1..151
                     /gene="Dele1"
                     /gene_synonym="0610009O20Rik; 2700004E22Rik; Dele;
                     DELE1(L); Kiaa0141"
                     /inference="alignment:Splign:2.1.0"
     exon            152..266
                     /gene="Dele1"
                     /gene_synonym="0610009O20Rik; 2700004E22Rik; Dele;
                     DELE1(L); Kiaa0141"
                     /inference="alignment:Splign:2.1.0"
     exon            267..384
                     /gene="Dele1"
                     /gene_synonym="0610009O20Rik; 2700004E22Rik; Dele;
                     DELE1(L); Kiaa0141"
                     /inference="alignment:Splign:2.1.0"
     exon            385..529
                     /gene="Dele1"
                     /gene_synonym="0610009O20Rik; 2700004E22Rik; Dele;
                     DELE1(L); Kiaa0141"
                     /inference="alignment:Splign:2.1.0"
     exon            530..691
                     /gene="Dele1"
                     /gene_synonym="0610009O20Rik; 2700004E22Rik; Dele;
                     DELE1(L); Kiaa0141"
                     /inference="alignment:Splign:2.1.0"
     exon            692..780
                     /gene="Dele1"
                     /gene_synonym="0610009O20Rik; 2700004E22Rik; Dele;
                     DELE1(L); Kiaa0141"
                     /inference="alignment:Splign:2.1.0"
     exon            781..877
                     /gene="Dele1"
                     /gene_synonym="0610009O20Rik; 2700004E22Rik; Dele;
                     DELE1(L); Kiaa0141"
                     /inference="alignment:Splign:2.1.0"
     exon            878..1020
                     /gene="Dele1"
                     /gene_synonym="0610009O20Rik; 2700004E22Rik; Dele;
                     DELE1(L); Kiaa0141"
                     /inference="alignment:Splign:2.1.0"
     exon            1021..1179
                     /gene="Dele1"
                     /gene_synonym="0610009O20Rik; 2700004E22Rik; Dele;
                     DELE1(L); Kiaa0141"
                     /inference="alignment:Splign:2.1.0"
     exon            1180..1272
                     /gene="Dele1"
                     /gene_synonym="0610009O20Rik; 2700004E22Rik; Dele;
                     DELE1(L); Kiaa0141"
                     /inference="alignment:Splign:2.1.0"
     exon            1273..1432
                     /gene="Dele1"
                     /gene_synonym="0610009O20Rik; 2700004E22Rik; Dele;
                     DELE1(L); Kiaa0141"
                     /inference="alignment:Splign:2.1.0"
     exon            1433..1654
                     /gene="Dele1"
                     /gene_synonym="0610009O20Rik; 2700004E22Rik; Dele;
                     DELE1(L); Kiaa0141"
                     /inference="alignment:Splign:2.1.0"
     exon            1655..2404
                     /gene="Dele1"
                     /gene_synonym="0610009O20Rik; 2700004E22Rik; Dele;
                     DELE1(L); Kiaa0141"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2379..2384
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Dele1"
                     /gene_synonym="0610009O20Rik; 2700004E22Rik; Dele;
                     DELE1(L); Kiaa0141"
                     /note="hexamer: AATAAA"
     polyA_site      2401
                     /gene="Dele1"
                     /gene_synonym="0610009O20Rik; 2700004E22Rik; Dele;
                     DELE1(L); Kiaa0141"
                     /note="major polyA site"
ORIGIN      
        1 cttgctgatt ggctggctgg ggactcggcc gctggggaca gcgcagcggc cactctggtc
       61 cctgtcccgt cctttgggcc tcgatccctc ggctgcaggc tctatggtgc tggccacgac
      121 atgtggcgcc tgacagggat cctggggcga gctcttcccc gcctgctggg acctggcttc
      181 cgtgggataa cgcccaaacc caccagttca gatgggtctc agacaacctc ccctaccctg
      241 ccgctcacta ggctcagctt tgacagatca ggttcccacg gttcaaagag gagcagggac
      301 ccaaagtgct gtggatggaa agatgccttt cactggatgt ctgctcatgt ctccccaaac
      361 acactgcggg acgccatctc atggggcact ctggcggtgc tggccttgca cctggcgagg
      421 cagatccact tccacgcccc tctggtagca ggacctcagc cagctgaacg ctcttggcac
      481 agtcccctgt accgcttcct ctcctcttcc tggtggcacc cacactcctc acttcggagg
      541 catgttcttc ccaggtctga ctgcccagct cccaggaaca ctggcctcag ggaaccaagg
      601 cagggccagg aagaccatcc ctcagctcca tcccagtgcc ttccctcaga tagctccctg
      661 agatctggac ttctgaatct gcctgaagaa gagcccagtg actttgactt cctgcatgct
      721 agccgagact tcgcatccca ggcaaaggca gccgaggccc acccccctgg aggaaaaaat
      781 gaacaagaca aggccaaggc tcttcctctg gaggaggctg tgacttccat tcagcaactc
      841 tttcagctca gtgtagccat cactttcaac ttcctgggga cagagaacat aaagacgggg
      901 gactacacgg cagccttttc ctacttccag aaagccgcag accgtggcta cagcaaagca
      961 cagtacaatg tgggcttgtg tctcgagcat ggcagaggca cccccaggga cctcagcaag
     1021 gctatcctct tttaccatct ggctgccgtc cagggccaca gcctggctca gtaccgctat
     1081 gccaggtgtc tgttgcaaag tccaggctct ttgtcagacc ctgagcgaga gagggcagtc
     1141 tctctgctga agcaggctgc agactctggc ttgacagagg cccaagcttt ccttggggtg
     1201 ctctttacta aggaaccaca cctggatgaa cagagagcag taaaatacct ctggctggcg
     1261 gccagcaatg gggattctca gagcagattc cacttgggaa tttgctatga gaagggcctt
     1321 ggtgcacaga ggaatctagg agaggccgtg aagtgctacc agcaggcagc agctatgggg
     1381 aatgaacccg cccgggagag gcttcggacc ctctttaacg tggaagcagc agggcccagc
     1441 cacctggcca cgacaggact gaagtctttc tccagcccct ccctctgcag cctgaacacc
     1501 ctgttggctg gtgcctcagg cctccctcat gcctcaagca ctgggaacct cggcctcctc
     1561 tgcagaagtg gccatctcgg agccagccat ggtgccccca gcaggactat accatccttg
     1621 gaaaggagcc tcgtaagact aggtttcggc taagacctcc tccttaaaga tggagcctga
     1681 gagttctcag agataccaca atttgagtcc caaagaagag gccagttagt tacttacctt
     1741 cccaggaacc atcagtacct ccccggcacc ataaggaaga ggaacgtgtg taaagacccg
     1801 ggctttggct gcgccgcctg gaagcagtga ctggatgtca accacatctc ctcagttgtc
     1861 gactgaggac tcctgcctta aaggattgag atgcagccat ttcaccatag aaagaacctt
     1921 actccttgct taggttcctg aagacagact ggtgcccaca gttccatggc cttaagaacc
     1981 accaggctgc tgggcatggt gagacacacc caatcccagc attcaggatg cagagaggca
     2041 ggcagatatc tatgagtttg aggccagcct ggtctaccag gtgagttcca ggacagccaa
     2101 ggcttgttat acagagaaac cctgtctcaa atcaccacca ccacccccac caccccccaa
     2161 aaaagaagaa gaagagtcac taggtcaaga tgaggatcaa agctgacatt atgactccag
     2221 ccaagacttc agtctaccag ttcacactgc attgttatct gaaaacatta tcatcaccct
     2281 acagatcagt ggagattagg cacctggagt cttggagcca gagagtggag accatgagtt
     2341 ctttttggga aaggtcaggt agggatatac aagtgtttaa taaaacagat ggtggattat
     2401 ctctaaa
//
