LOCUS       NM_030734                328 bp    mRNA    linear   ROD 13-JUN-2024
DEFINITION  Mus musculus defensin beta 5 (Defb5), mRNA.
ACCESSION   NM_030734
VERSION     NM_030734.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 328)
  AUTHORS   Amid,C., Rehaume,L.M., Brown,K.L., Gilbert,J.G., Dougan,G.,
            Hancock,R.E. and Harrow,J.L.
  TITLE     Manual annotation and analysis of the defensin gene cluster in the
            C57BL/6J mouse reference genome
  JOURNAL   BMC Genomics 10, 606 (2009)
   PUBMED   20003482
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 328)
  AUTHORS   Morrison,G.M., Semple,C.A., Kilanowski,F.M., Hill,R.E. and
            Dorin,J.R.
  TITLE     Signal sequence conservation and mature peptide divergence within
            subgroups of the murine beta-defensin gene family
  JOURNAL   Mol Biol Evol 20 (3), 460-470 (2003)
   PUBMED   12644567
REFERENCE   3  (bases 1 to 328)
  AUTHORS   Yamaguchi,Y., Nagase,T., Makita,R., Fukuhara,S., Tomita,T.,
            Tominaga,T., Kurihara,H. and Ouchi,Y.
  TITLE     Identification of multiple novel epididymis-specific beta-defensin
            isoforms in humans and mice
  JOURNAL   J Immunol 169 (5), 2516-2523 (2002)
   PUBMED   12193721
  REMARK    GeneRIF: The epididymis-specific expression pattern of
            beta-defensin isoform 5 has been characterized.
REFERENCE   4  (bases 1 to 328)
  AUTHORS   Morrison,G.M., Rolfe,M., Kilanowski,F.M., Cross,S.H. and Dorin,J.R.
  TITLE     Identification and characterization of a novel murine
            beta-defensin-related gene
  JOURNAL   Mamm Genome 13 (8), 445-451 (2002)
   PUBMED   12226710
  REMARK    Erratum:[Mamm Genome. 2002 Oct;13(10):603]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC163997.3.
            
            On Sep 2, 2022 this sequence version replaced NM_030734.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF318068.1 [ECO:0000332]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-82                AC163997.3         18109-18190         c
            83-328              AC163997.3         14821-15066         c
FEATURES             Location/Qualifiers
     source          1..328
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 10.35 cM"
     gene            1..328
                     /gene="Defb5"
                     /gene_synonym="BD-5"
                     /note="defensin beta 5"
                     /db_xref="GeneID:81007"
                     /db_xref="MGI:MGI:1933153"
     exon            1..82
                     /gene="Defb5"
                     /gene_synonym="BD-5"
                     /inference="alignment:Splign:2.1.0"
     CDS             21..215
                     /gene="Defb5"
                     /gene_synonym="BD-5"
                     /note="beta-defensin 5"
                     /codon_start=1
                     /product="beta-defensin 5 precursor"
                     /protein_id="NP_109659.2"
                     /db_xref="CCDS:CCDS40257.1"
                     /db_xref="GeneID:81007"
                     /db_xref="MGI:MGI:1933153"
                     /translation="MKIHYLLFAFLLVLLSPLAGVFSKTINNPVSCCMIGGICRYLCK
                     GNILQNGSCGVTSLNCCKRK"
     exon            83..328
                     /gene="Defb5"
                     /gene_synonym="BD-5"
                     /inference="alignment:Splign:2.1.0"
     regulatory      304..309
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Defb5"
                     /gene_synonym="BD-5"
                     /note="hexamer: ATTAAA"
     polyA_site      328
                     /gene="Defb5"
                     /gene_synonym="BD-5"
                     /note="major polyA site"
ORIGIN      
        1 cccctcacca ggcttcagcc atgaagatcc attaccttct ctttgcattt ctcctggtgc
       61 tgctgtctcc acttgcaggt gtctttagca aaacaatcaa caatccagta agttgctgta
      121 tgattggagg catatgcagg tatctgtgca agggcaacat tcttcagaat ggcagttgtg
      181 gagttactag tctcaactgc tgcaagagaa aatagagaag aagtcaaaga tccagtgaac
      241 caaagaaaac aatttgcacc tccatgaaga tgaacaaaac ataaactaaa ttaaagttcc
      301 ttgattaaat gcaaacgcat gttggtaa
//
