LOCUS       NM_001039125             359 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus defensin beta 47 (Defb47), mRNA.
ACCESSION   NM_001039125
VERSION     NM_001039125.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 359)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 359)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   3  (bases 1 to 359)
  AUTHORS   Amid,C., Rehaume,L.M., Brown,K.L., Gilbert,J.G., Dougan,G.,
            Hancock,R.E. and Harrow,J.L.
  TITLE     Manual annotation and analysis of the defensin gene cluster in the
            C57BL/6J mouse reference genome
  JOURNAL   BMC Genomics 10, 606 (2009)
   PUBMED   20003482
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 359)
  AUTHORS   Patil,A.A., Cai,Y., Sang,Y., Blecha,F. and Zhang,G.
  TITLE     Cross-species analysis of the mammalian beta-defensin gene family:
            presence of syntenic gene clusters and preferential expression in
            the male reproductive tract
  JOURNAL   Physiol Genomics 23 (1), 5-17 (2005)
   PUBMED   16033865
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC132604.1.
            
            On Apr 29, 2010 this sequence version replaced NM_001039125.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC132604.1, DQ012043.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849376, SAMN00849381
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..359
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="14"
                     /map="14 33.23 cM"
     gene            1..359
                     /gene="Defb47"
                     /gene_synonym="Defb41; EG654465"
                     /note="defensin beta 47"
                     /db_xref="GeneID:654465"
                     /db_xref="MGI:MGI:3644478"
     exon            1..83
                     /gene="Defb47"
                     /gene_synonym="Defb41; EG654465"
                     /inference="alignment:Splign:2.1.0"
     CDS             26..265
                     /gene="Defb47"
                     /gene_synonym="Defb41; EG654465"
                     /note="defensin beta 41"
                     /codon_start=1
                     /product="beta-defensin 130B precursor"
                     /protein_id="NP_001034214.1"
                     /db_xref="CCDS:CCDS36945.1"
                     /db_xref="GeneID:654465"
                     /db_xref="MGI:MGI:3644478"
                     /translation="MRSRSFLPVLFLFVMMMLRGKAGLVPGEKQCISLKGICKDLACT
                     SSDDTIGVCNDVKKCCRKWWVFEPYPTPVPKGKSP"
     exon            84..359
                     /gene="Defb47"
                     /gene_synonym="Defb41; EG654465"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cttccacact gctggccact cgaccatgcg atcccgttcc ttcctgcctg tcctcttcct
       61 ctttgtgatg atgatgctga gaggaaaggc tggccttgtc ccaggggaaa agcagtgcat
      121 ttcgttgaaa ggaatatgca aagacctagc gtgcacatcc tcagacgata ctattggcgt
      181 atgtaacgac gtgaagaagt gttgtaggaa gtggtgggtg tttgaaccct acccaacacc
      241 cgttcccaaa ggaaagtctc cttagaggga agaacatgat aagcccttca aactccagaa
      301 aacatggacg agctctgcag agttctgctt actacactca ccttctccct tgcctgcaa
//
