LOCUS       NM_183039                380 bp    mRNA    linear   ROD 12-OCT-2024
DEFINITION  Mus musculus defensin beta 40 (Defb40), mRNA.
ACCESSION   NM_183039
VERSION     NM_183039.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 380)
  AUTHORS   Amid,C., Rehaume,L.M., Brown,K.L., Gilbert,J.G., Dougan,G.,
            Hancock,R.E. and Harrow,J.L.
  TITLE     Manual annotation and analysis of the defensin gene cluster in the
            C57BL/6J mouse reference genome
  JOURNAL   BMC Genomics 10, 606 (2009)
   PUBMED   20003482
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 380)
  AUTHORS   Zaballos,A., Villares,R., Albar,J.P., Martinez-A,C. and Marquez,G.
  TITLE     Identification on mouse chromosome 8 of new beta-defensin genes
            with regionally specific expression in the male reproductive organ
  JOURNAL   J Biol Chem 279 (13), 12421-12426 (2004)
   PUBMED   14718547
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC119161.8.
            
            On Jun 19, 2019 this sequence version replaced NM_183039.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AJ575426.1, AJ578473.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849376, SAMN00849381
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-166               AC119161.8         109628-109793
            167-380             AC119161.8         112722-112935
FEATURES             Location/Qualifiers
     source          1..380
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 10.35 cM"
     gene            1..380
                     /gene="Defb40"
                     /gene_synonym="BD-40"
                     /note="defensin beta 40"
                     /db_xref="GeneID:360217"
                     /db_xref="MGI:MGI:2672976"
     exon            1..166
                     /gene="Defb40"
                     /gene_synonym="BD-40"
                     /inference="alignment:Splign:2.1.0"
     CDS             106..327
                     /gene="Defb40"
                     /gene_synonym="BD-40"
                     /note="beta-defensin 40"
                     /codon_start=1
                     /product="beta-defensin 40 precursor"
                     /protein_id="NP_898860.3"
                     /db_xref="CCDS:CCDS40246.1"
                     /db_xref="GeneID:360217"
                     /db_xref="MGI:MGI:2672976"
                     /translation="MKISCFLLMIFFLSCFQINPVAVLDTIKCLQGNNNCHIQKCPWF
                     LLQVSTCYKGKGRCCQKRRWFARNHVYHV"
     exon            167..380
                     /gene="Defb40"
                     /gene_synonym="BD-40"
                     /inference="alignment:Splign:2.1.0"
     regulatory      338..343
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Defb40"
                     /gene_synonym="BD-40"
                     /note="hexamer: AATAAA"
     polyA_site      380
                     /gene="Defb40"
                     /gene_synonym="BD-40"
                     /note="major polyA site"
ORIGIN      
        1 gttcttcctc tctatgactg cagatacact ctgtgctctg aattcacctt tagctaagct
       61 ttccatcact ggccctgact gtaatcagct ctgcgtgcag caaccatgaa gatctcctgc
      121 tttctactga tgatcttctt tctatcatgc tttcagatca acccagttgc tgttcttgac
      181 acaataaaat gtctccaagg aaacaacaac tgtcacattc agaaatgccc atggttttta
      241 cttcaagtta gcacctgtta taaaggaaag ggcagatgtt gccaaaaacg ccgttggttt
      301 gccagaaatc atgtgtacca tgtgtaacca ttgctttaat aaaggaaaaa acccagaggt
      361 gtagcttctt cataccaaaa
//
