LOCUS       NM_181683                336 bp    mRNA    linear   ROD 12-JUN-2024
DEFINITION  Mus musculus defensin beta 37 (Defb37), mRNA.
ACCESSION   NM_181683
VERSION     NM_181683.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 336)
  AUTHORS   Amid,C., Rehaume,L.M., Brown,K.L., Gilbert,J.G., Dougan,G.,
            Hancock,R.E. and Harrow,J.L.
  TITLE     Manual annotation and analysis of the defensin gene cluster in the
            C57BL/6J mouse reference genome
  JOURNAL   BMC Genomics 10, 606 (2009)
   PUBMED   20003482
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 336)
  AUTHORS   Zaballos,A., Villares,R., Albar,J.P., Martinez-A,C. and Marquez,G.
  TITLE     Identification on mouse chromosome 8 of new beta-defensin genes
            with regionally specific expression in the male reproductive organ
  JOURNAL   J Biol Chem 279 (13), 12421-12426 (2004)
   PUBMED   14718547
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC119161.8.
            
            On Sep 2, 2022 this sequence version replaced NM_181683.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AJ489588.1, AJ578470.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849377, SAMN00849380
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-144               AC119161.8         96793-96936
            145-336             AC119161.8         101408-101599
FEATURES             Location/Qualifiers
     source          1..336
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 10.35 cM"
     gene            1..336
                     /gene="Defb37"
                     /gene_synonym="BD-37"
                     /note="defensin beta 37"
                     /db_xref="GeneID:353320"
                     /db_xref="MGI:MGI:2672966"
     exon            1..144
                     /gene="Defb37"
                     /gene_synonym="BD-37"
                     /inference="alignment:Splign:2.1.0"
     CDS             84..272
                     /gene="Defb37"
                     /gene_synonym="BD-37"
                     /note="beta-defensin 37"
                     /codon_start=1
                     /product="beta-defensin 37 precursor"
                     /protein_id="NP_859011.1"
                     /db_xref="CCDS:CCDS40247.1"
                     /db_xref="GeneID:353320"
                     /db_xref="MGI:MGI:2672966"
                     /translation="MKFSYFLLLLLSLSNFQNNPVAMLDTIACIENKDTCRLKNCPRL
                     HNVVGTCYEGKGKCCHKN"
     exon            145..336
                     /gene="Defb37"
                     /gene_synonym="BD-37"
                     /inference="alignment:Splign:2.1.0"
     regulatory      316..321
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Defb37"
                     /gene_synonym="BD-37"
                     /note="hexamer: AATAAA"
     polyA_site      336
                     /gene="Defb37"
                     /gene_synonym="BD-37"
                     /note="major polyA site"
ORIGIN      
        1 atgcactctg tgttctgggt tcatctttga gctaagcttt ctagctctgg ccttgtcttt
       61 aatcagctca gtgtgctgca atcatgaagt tctcctactt tctgctgctg ctcctctctc
      121 tatccaactt ccagaacaac ccagttgcta tgcttgacac aatagcatgt attgagaata
      181 aagacacctg tcgcctcaag aactgcccac gccttcataa tgtagttggc acctgttatg
      241 aaggaaaagg caagtgttgc cacaaaaact gatgatacgt cagaacttgc aagaagaaag
      301 tgaaaccatt gctgtaataa aggaaaacat actgaa
//
