LOCUS       NM_001037247             470 bp    mRNA    linear   ROD 30-JUL-2024
DEFINITION  Mus musculus defensin beta 36 (Defb36), mRNA.
ACCESSION   NM_001037247 XM_485085
VERSION     NM_001037247.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 470)
  AUTHORS   Patil,A.A., Cai,Y., Sang,Y., Blecha,F. and Zhang,G.
  TITLE     Cross-species analysis of the mammalian beta-defensin gene family:
            presence of syntenic gene clusters and preferential expression in
            the male reproductive tract
  JOURNAL   Physiol Genomics 23 (1), 5-17 (2005)
   PUBMED   16033865
REFERENCE   2  (bases 1 to 470)
  AUTHORS   Schutte,B.C., Mitros,J.P., Bartlett,J.A., Walters,J.D., Jia,H.P.,
            Welsh,M.J., Casavant,T.L. and McCray,P.B. Jr.
  TITLE     Discovery of five conserved beta -defensin gene clusters using a
            computational search strategy
  JOURNAL   Proc Natl Acad Sci U S A 99 (4), 2129-2133 (2002)
   PUBMED   11854508
  REMARK    Erratum:[Proc Natl Acad Sci U S A 2002 Oct 29;99(22):14611]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DQ012042.1 and BX631384.1.
            
            On Apr 28, 2010 this sequence version replaced NM_001037247.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: DQ012042.1, CB316646.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849379
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-465               DQ012042.1         1-465
            466-470             BX631384.1         1-5                 c
FEATURES             Location/Qualifiers
     source          1..470
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 75.41 cM"
     gene            1..470
                     /gene="Defb36"
                     /gene_synonym="BD-36; Defb123; mBD-36"
                     /note="defensin beta 36"
                     /db_xref="GeneID:266620"
                     /db_xref="MGI:MGI:2385956"
     exon            1..219
                     /gene="Defb36"
                     /gene_synonym="BD-36; Defb123; mBD-36"
                     /inference="alignment:Splign:2.1.0"
     CDS             162..365
                     /gene="Defb36"
                     /gene_synonym="BD-36; Defb123; mBD-36"
                     /note="beta-defensin 36; defensin beta 123"
                     /codon_start=1
                     /product="beta-defensin 36 precursor"
                     /protein_id="NP_001032324.1"
                     /db_xref="CCDS:CCDS38279.1"
                     /db_xref="GeneID:266620"
                     /db_xref="MGI:MGI:2385956"
                     /translation="MKLLLLTLAALLLVSQLTPGDAQKCWNLHGKCRHRCSRKESVYV
                     YCTNGKMCCVKPKYQPKPKPWMF"
     exon            220..468
                     /gene="Defb36"
                     /gene_synonym="BD-36; Defb123; mBD-36"
                     /inference="alignment:Splign:2.1.0"
     regulatory      445..450
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Defb36"
                     /gene_synonym="BD-36; Defb123; mBD-36"
                     /note="hexamer: AATAAA"
     polyA_site      468
                     /gene="Defb36"
                     /gene_synonym="BD-36; Defb123; mBD-36"
                     /note="major polyA site"
ORIGIN      
        1 ggtgtggctc cacattttag acccggggta cgggactgtt cccgttggct gctcctggag
       61 atctgagagg tttccgccag gaagtctcgg cctccccagt acgccacgaa cgttgctttg
      121 gactcgaagc ttcgaagctt cgccttgggc cttctcccac gatgaagctc ctgctgctga
      181 ctttggctgc gctcctgctc gtgtcccagc tcactccagg tgatgctcag aaatgctgga
      241 atctccacgg caagtgccgc caccgatgct ccaggaagga gagcgtctac gtctactgca
      301 caaacgggaa gatgtgttgc gtgaagccca aataccagcc gaagccaaag ccgtggatgt
      361 tctaactgcc cagaagcctg aagcccagat aatacagatg gcaaagctgt cctaggttga
      421 ccccatggat tcttgagttc agtcaataaa cgtgcttgcc caacctcaaa
//
