LOCUS       NM_139224                267 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus defensin beta 35 (Defb35), mRNA.
ACCESSION   NM_139224
VERSION     NM_139224.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 267)
  AUTHORS   Amid,C., Rehaume,L.M., Brown,K.L., Gilbert,J.G., Dougan,G.,
            Hancock,R.E. and Harrow,J.L.
  TITLE     Manual annotation and analysis of the defensin gene cluster in the
            C57BL/6J mouse reference genome
  JOURNAL   BMC Genomics 10, 606 (2009)
   PUBMED   20003482
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 267)
  AUTHORS   Zaballos,A., Villares,R., Albar,J.P., Martinez-A,C. and Marquez,G.
  TITLE     Identification on mouse chromosome 8 of new beta-defensin genes
            with regionally specific expression in the male reproductive organ
  JOURNAL   J Biol Chem 279 (13), 12421-12426 (2004)
   PUBMED   14718547
REFERENCE   3  (bases 1 to 267)
  AUTHORS   Morrison,G.M., Semple,C.A., Kilanowski,F.M., Hill,R.E. and
            Dorin,J.R.
  TITLE     Signal sequence conservation and mature peptide divergence within
            subgroups of the murine beta-defensin gene family
  JOURNAL   Mol Biol Evol 20 (3), 460-470 (2003)
   PUBMED   12644567
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AJ437650.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AJ437650.1 [ECO:0000332]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..267
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 10.66 cM"
     gene            1..267
                     /gene="Defb35"
                     /gene_synonym="BD-35"
                     /note="defensin beta 35"
                     /db_xref="GeneID:246084"
                     /db_xref="MGI:MGI:2179204"
     CDS             1..192
                     /gene="Defb35"
                     /gene_synonym="BD-35"
                     /function="antimicrobial peptide"
                     /note="beta-defensin 35"
                     /codon_start=1
                     /product="beta-defensin 35 precursor"
                     /protein_id="NP_631970.1"
                     /db_xref="CCDS:CCDS52516.1"
                     /db_xref="GeneID:246084"
                     /db_xref="MGI:MGI:2179204"
                     /translation="MPQTFFVFCFLFFVFLQLFPGTGEIAVCETCRLGRGKCRRACIE
                     SEKIVGWCKLNFFCCRERI"
     exon            1..48
                     /gene="Defb35"
                     /gene_synonym="BD-35"
                     /inference="alignment:Splign:2.1.0"
     exon            49..267
                     /gene="Defb35"
                     /gene_synonym="BD-35"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atgcctcaga cgttttttgt tttttgtttt ttgttttttg tttttttgca gctctttcct
       61 ggcacagggg agattgctgt gtgcgagaca tgcaggctcg gccggggaaa atgcaggaga
      121 gcatgcatag agagtgagaa gattgtgggc tggtgcaagc tgaacttctt ctgctgtcga
      181 gagaggatct gaacccaacg accaatggcc tttggacctt gcaagccgtg ctgaatggat
      241 ggtcaaggag agaacatctg tgacttc
//
