LOCUS       NM_001039566            1020 bp    mRNA    linear   ROD 07-AUG-2024
DEFINITION  Mus musculus defensin beta 30 (Defb30), transcript variant 1, mRNA.
ACCESSION   NM_001039566
VERSION     NM_001039566.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1020)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1020)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1020)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24643. PMID: 29144450]
REFERENCE   4  (bases 1 to 1020)
  AUTHORS   Amid,C., Rehaume,L.M., Brown,K.L., Gilbert,J.G., Dougan,G.,
            Hancock,R.E. and Harrow,J.L.
  TITLE     Manual annotation and analysis of the defensin gene cluster in the
            C57BL/6J mouse reference genome
  JOURNAL   BMC Genomics 10, 606 (2009)
   PUBMED   20003482
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1020)
  AUTHORS   Patil,A.A., Cai,Y., Sang,Y., Blecha,F. and Zhang,G.
  TITLE     Cross-species analysis of the mammalian beta-defensin gene family:
            presence of syntenic gene clusters and preferential expression in
            the male reproductive tract
  JOURNAL   Physiol Genomics 23 (1), 5-17 (2005)
   PUBMED   16033865
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC090659.19.
            
            On Oct 7, 2022 this sequence version replaced NM_001039566.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: DQ012040.1, AK078987.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-107               AC090659.19        153268-153374       c
            108-279             AC090659.19        151440-151611       c
            280-1020            AC090659.19        149597-150337       c
FEATURES             Location/Qualifiers
     source          1..1020
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="14"
                     /map="14 33.23 cM"
     gene            1..1020
                     /gene="Defb30"
                     /gene_synonym="2410125J01Rik; 4930449O14Rik; BD-30;
                     mBD-30"
                     /note="defensin beta 30"
                     /db_xref="GeneID:73670"
                     /db_xref="MGI:MGI:1920920"
     exon            1..107
                     /gene="Defb30"
                     /gene_synonym="2410125J01Rik; 4930449O14Rik; BD-30;
                     mBD-30"
                     /inference="alignment:Splign:2.1.0"
     exon            108..279
                     /gene="Defb30"
                     /gene_synonym="2410125J01Rik; 4930449O14Rik; BD-30;
                     mBD-30"
                     /inference="alignment:Splign:2.1.0"
     exon            280..1020
                     /gene="Defb30"
                     /gene_synonym="2410125J01Rik; 4930449O14Rik; BD-30;
                     mBD-30"
                     /inference="alignment:Splign:2.1.0"
     regulatory      610..615
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Defb30"
                     /gene_synonym="2410125J01Rik; 4930449O14Rik; BD-30;
                     mBD-30"
                     /note="hexamer: AATAAA"
     polyA_site      637
                     /gene="Defb30"
                     /gene_synonym="2410125J01Rik; 4930449O14Rik; BD-30;
                     mBD-30"
                     /note="major polyA site"
ORIGIN      
        1 actcttcttt gcatctcaga tgactctctg ctcactgggt tgattgacaa tggggagcct
       61 acagttgacc ctcgtgctct ttgtcttgct ctcctatgtt ccaccagtta gaagtggggt
      121 gaatatgtac ataaaacgga tttacgacac atgctggaaa ctaaaaggca tttgcaggaa
      181 tacatgtcaa aaagaagaaa tttatcacat tttctgtggc attcagtcgt tgtgctgctt
      241 agagaaaaag gaaatgcccg ttctcttcgt gaagtagctg tcacacttgg ttttagtaga
      301 tccacatgtc gttgcggacc cagaaatctc acctctgtct ttcagattgc ttgcaccaat
      361 ttccattctc tatgttgtta gtaaatactt tggatcccgg ctagtgttct ctaccctact
      421 cccctctggg gtattatact aatgatacat ggtaactgaa tttgaatttc acctctgatt
      481 aataggtgtt tactaaatgg tcatatgtct ttgcttgtga ctggggcaca gctcgaggtt
      541 aaagcacttg cctgtgtatc cttagtcacg acgtgcttgt tcataatttg atgtagaaaa
      601 tagtaaaaaa ataaaagtca tttggaaaac acctaaatcg aagtattgag tgagttgcag
      661 tttatcagac atacttagca gtttgttttc tactgcttac atcacttaaa tgtggctgtt
      721 gtgctgaggt tgtagctcag cttgtagagg gcttgcctag catgcatgaa gtctggggtt
      781 catttccagc cgatcacagg catgcatcac cacacttggc ttctggattt tctaaccatt
      841 gtgaaaagtg aacattgaaa ttgttttact aatattgtgc tgctgtcaac ttctcttttc
      901 agatttgcca atttttgctt tgtatacttg aatttcttag atgcaaggat catatatata
      961 tatatatata tatatttata tctatctatc tatctatact gttaaaataa aagaattatt
//
