LOCUS       NM_001039122             324 bp    mRNA    linear   ROD 13-JUN-2024
DEFINITION  Mus musculus defensin beta 25 (Defb25), mRNA.
ACCESSION   NM_001039122
VERSION     NM_001039122.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 324)
  AUTHORS   Patil,A.A., Cai,Y., Sang,Y., Blecha,F. and Zhang,G.
  TITLE     Cross-species analysis of the mammalian beta-defensin gene family:
            presence of syntenic gene clusters and preferential expression in
            the male reproductive tract
  JOURNAL   Physiol Genomics 23 (1), 5-17 (2005)
   PUBMED   16033865
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL845162.9.
            
            On Nov 8, 2022 this sequence version replaced NM_001039122.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: DQ012036.1, CR522163.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-113               AL845162.9         103692-103804       c
            114-324             AL845162.9         103076-103286       c
FEATURES             Location/Qualifiers
     source          1..324
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 75.41 cM"
     gene            1..324
                     /gene="Defb25"
                     /gene_synonym="BD-25; mBD-25"
                     /note="defensin beta 25"
                     /db_xref="GeneID:654459"
                     /db_xref="MGI:MGI:3651158"
     exon            1..113
                     /gene="Defb25"
                     /gene_synonym="BD-25; mBD-25"
                     /inference="alignment:Splign:2.1.0"
     CDS             56..271
                     /gene="Defb25"
                     /gene_synonym="BD-25; mBD-25"
                     /note="beta-defensin 25"
                     /codon_start=1
                     /product="beta-defensin 25 precursor"
                     /protein_id="NP_001034211.1"
                     /db_xref="CCDS:CCDS38280.1"
                     /db_xref="GeneID:654459"
                     /db_xref="MGI:MGI:3651158"
                     /translation="MAKWILLIVALLVLSHVPPGSTEFKRCWNGQGACRTFCTRQETF
                     MHLCPDASLCCLSYSFKPSRPSRVGDV"
     exon            114..324
                     /gene="Defb25"
                     /gene_synonym="BD-25; mBD-25"
                     /inference="alignment:Splign:2.1.0"
     regulatory      302..307
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Defb25"
                     /gene_synonym="BD-25; mBD-25"
                     /note="hexamer: AATAAA"
     polyA_site      324
                     /gene="Defb25"
                     /gene_synonym="BD-25; mBD-25"
                     /note="major polyA site"
ORIGIN      
        1 atgcttcgct cctcccctga cttcttcccg caatcttccc aggagcttgg tggccatggc
       61 aaagtggatt ctgctcattg tggctctcct ggtcctgagt catgtaccac caggaagcac
      121 tgaattcaaa cggtgctgga acggccaagg agcctgccgg actttctgca caaggcaaga
      181 gaccttcatg cacctgtgtc cggatgcttc tctgtgttgc ctgtcctatt ctttcaagcc
      241 ttcacgcccc tcaagggttg gagatgtgta gcttgctcta gagttgatgc catcactgcc
      301 caataaaatt catgtcatca gctc
//
