LOCUS       NM_001039123             362 bp    mRNA    linear   ROD 04-AUG-2024
DEFINITION  Mus musculus defensin beta 18 (Defb18), mRNA.
ACCESSION   NM_001039123
VERSION     NM_001039123.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 362)
  AUTHORS   Patil,A.A., Cai,Y., Sang,Y., Blecha,F. and Zhang,G.
  TITLE     Cross-species analysis of the mammalian beta-defensin gene family:
            presence of syntenic gene clusters and preferential expression in
            the male reproductive tract
  JOURNAL   Physiol Genomics 23 (1), 5-17 (2005)
   PUBMED   16033865
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC161367.4.
            
            On Jun 21, 2019 this sequence version replaced NM_001039123.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: DQ012029.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-103               AC161367.4         168747-168849       c
            104-362             AC161367.4         167775-168033       c
FEATURES             Location/Qualifiers
     source          1..362
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 5.7 cM"
     gene            1..362
                     /gene="Defb18"
                     /gene_synonym="BD-18; EG654460; mBD-18"
                     /note="defensin beta 18"
                     /db_xref="GeneID:654460"
                     /db_xref="MGI:MGI:3648148"
     exon            1..103
                     /gene="Defb18"
                     /gene_synonym="BD-18; EG654460; mBD-18"
                     /inference="alignment:Splign:2.1.0"
     CDS             34..291
                     /gene="Defb18"
                     /gene_synonym="BD-18; EG654460; mBD-18"
                     /note="beta-defensin 18"
                     /codon_start=1
                     /product="beta-defensin 18 precursor"
                     /protein_id="NP_001034212.1"
                     /db_xref="CCDS:CCDS35520.1"
                     /db_xref="GeneID:654460"
                     /db_xref="MGI:MGI:3648148"
                     /translation="MQSTMKMFGIILMVIFSVSCGPSAPQMKTREVAERTHKCSLVRG
                     TCKSECNSWEYKYNYCHTEPCCVVREYKRMEKLLSTPKYTT"
     exon            104..362
                     /gene="Defb18"
                     /gene_synonym="BD-18; EG654460; mBD-18"
                     /inference="alignment:Splign:2.1.0"
     regulatory      339..344
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Defb18"
                     /gene_synonym="BD-18; EG654460; mBD-18"
                     /note="hexamer: AATAAA"
     polyA_site      362
                     /gene="Defb18"
                     /gene_synonym="BD-18; EG654460; mBD-18"
                     /note="major polyA site"
ORIGIN      
        1 ataaactctt tgaactctaa ttccacctta agaatgcaat caacaatgaa gatgtttggc
       61 atcatcctga tggttatctt ctctgtgtcc tgtggtcctt ctgctcctca gatgaaaaca
      121 agagaggttg cagaaagaac acacaaatgt tccctggtcc gtggtacatg caagtctgaa
      181 tgtaacagtt gggagtataa atataactac tgtcacactg agccctgctg tgtggtgcga
      241 gaatacaaaa gaatggagaa attattgagt actcccaaat atacaactta aagtatgaat
      301 tgtaaatcta atacatgatt gaaactatac aaattactaa taaaattgga tttttaagtt
      361 tg
//
