LOCUS       NM_152802                998 bp    mRNA    linear   ROD 13-OCT-2024
DEFINITION  Mus musculus defensin beta 12 (Defb12), mRNA.
ACCESSION   NM_152802
VERSION     NM_152802.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 998)
  AUTHORS   Amid,C., Rehaume,L.M., Brown,K.L., Gilbert,J.G., Dougan,G.,
            Hancock,R.E. and Harrow,J.L.
  TITLE     Manual annotation and analysis of the defensin gene cluster in the
            C57BL/6J mouse reference genome
  JOURNAL   BMC Genomics 10, 606 (2009)
   PUBMED   20003482
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 998)
  AUTHORS   Zaballos,A., Villares,R., Albar,J.P., Martinez-A,C. and Marquez,G.
  TITLE     Identification on mouse chromosome 8 of new beta-defensin genes
            with regionally specific expression in the male reproductive organ
  JOURNAL   J Biol Chem 279 (13), 12421-12426 (2004)
   PUBMED   14718547
REFERENCE   3  (bases 1 to 998)
  AUTHORS   Yamaguchi,Y., Nagase,T., Makita,R., Fukuhara,S., Tomita,T.,
            Tominaga,T., Kurihara,H. and Ouchi,Y.
  TITLE     Identification of multiple novel epididymis-specific beta-defensin
            isoforms in humans and mice
  JOURNAL   J Immunol 169 (5), 2516-2523 (2002)
   PUBMED   12193721
  REMARK    GeneRIF: The epididymis-specific expression pattern of
            beta-defensin isoform mBD-12 has been characterized.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC116394.22.
            
            On Apr 6, 2021 this sequence version replaced NM_152802.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK020311.1, AB089182.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN01164132
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            RefSeq Select criteria           :: based on single protein-coding
                                                transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-105               AC116394.22        66962-67066         c
            106-147             AC116394.22        66559-66600         c
            148-998             AC116394.22        64163-65013         c
FEATURES             Location/Qualifiers
     source          1..998
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 10.35 cM"
     gene            1..998
                     /gene="Defb12"
                     /gene_synonym="9230103N16Rik; BD-12"
                     /note="defensin beta 12"
                     /db_xref="GeneID:77674"
                     /db_xref="MGI:MGI:1924924"
     exon            1..105
                     /gene="Defb12"
                     /gene_synonym="9230103N16Rik; BD-12"
                     /inference="alignment:Splign:2.1.0"
     CDS             36..272
                     /gene="Defb12"
                     /gene_synonym="9230103N16Rik; BD-12"
                     /note="beta-defensin 12"
                     /codon_start=1
                     /product="beta-defensin 12 precursor"
                     /protein_id="NP_690015.2"
                     /db_xref="CCDS:CCDS52496.1"
                     /db_xref="GeneID:77674"
                     /db_xref="MGI:MGI:1924924"
                     /translation="MALSREVFYFGFALFFIVVELPSGSWAGLEYSQSFPGGEIAVCE
                     TCRLGRGKCRRTCIESEKIAGWCKLNFFCCRERI"
     exon            106..147
                     /gene="Defb12"
                     /gene_synonym="9230103N16Rik; BD-12"
                     /inference="alignment:Splign:2.1.0"
     exon            148..998
                     /gene="Defb12"
                     /gene_synonym="9230103N16Rik; BD-12"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cccgattctc tgtgatgaag aatctcccct caaacatggc tctgagcaga gaggtgttct
       61 attttggttt tgctttgttc ttcattgtag ttgaactgcc atcagggtcc tgggcaggac
      121 ttgagtattc ccagtcattt ccaggagggg agattgctgt gtgcgagaca tgcaggctcg
      181 gccggggaaa atgcaggaga acatgcatag agagtgagaa gattgcgggc tggtgcaagc
      241 tgaacttctt ctgctgtcga gagaggatct gaacccaacg accaatggtc tttggacctt
      301 gcaagtcgtg ctgaatggat ggtcaaggag agaacatctg tggcttccca ggccacaatc
      361 agcgctgctc aggcccgtct cacctcagtc tgtctctgtg cttcatttga attttaagac
      421 gaccaaaatc aaaacagcaa tgaatgcctt ctacacaagc agacacaact gcacaactcc
      481 agaacactca taacttataa ctgttctttc cagaattgtc tcatagggct cagggtcacc
      541 tgagagtgtg actatcatcc ttatttgtat ttgatacagg tattttattt gtattgtcgt
      601 ctgtagtaca gcaaacctgg gagacaaggg acagtgtggg catcactacc tctttctgtg
      661 tctctaacat actaattatt atgggattaa tagacaaacg aaagtgctat gctcctctat
      721 gttgacagct ttgtagttct atagactaca agaaaaaatg cattcctttg attcttgatg
      781 aggtgatgta ttattatcca cagattataa aaattatgat atatattttt aaaaaaaccc
      841 tcatttactc tagtaatgcc ggtgcttctg aaacacattg tccttgcctg caagaagaaa
      901 tggttagcta ttaattaaaa tgtctattta cataggatat ctgcagatga aaaaactgta
      961 actttgcctt gtgaaataaa atttgcagct tcaaaaac
//
