LOCUS       NM_139225                298 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus defensin beta 10 (Defb10), mRNA.
ACCESSION   NM_139225
VERSION     NM_139225.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 298)
  AUTHORS   Amid,C., Rehaume,L.M., Brown,K.L., Gilbert,J.G., Dougan,G.,
            Hancock,R.E. and Harrow,J.L.
  TITLE     Manual annotation and analysis of the defensin gene cluster in the
            C57BL/6J mouse reference genome
  JOURNAL   BMC Genomics 10, 606 (2009)
   PUBMED   20003482
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 298)
  AUTHORS   Morrison,G.M., Semple,C.A., Kilanowski,F.M., Hill,R.E. and
            Dorin,J.R.
  TITLE     Signal sequence conservation and mature peptide divergence within
            subgroups of the murine beta-defensin gene family
  JOURNAL   Mol Biol Evol 20 (3), 460-470 (2003)
   PUBMED   12644567
REFERENCE   3  (bases 1 to 298)
  AUTHORS   Schutte,B.C., Mitros,J.P., Bartlett,J.A., Walters,J.D., Jia,H.P.,
            Welsh,M.J., Casavant,T.L. and McCray,P.B. Jr.
  TITLE     Discovery of five conserved beta -defensin gene clusters using a
            computational search strategy
  JOURNAL   Proc Natl Acad Sci U S A 99 (4), 2129-2133 (2002)
   PUBMED   11854508
  REMARK    Erratum:[Proc Natl Acad Sci U S A 2002 Oct 29;99(22):14611]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AJ437645.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AJ437645.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849376, SAMN00849381
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..298
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 10.49 cM"
     gene            1..298
                     /gene="Defb10"
                     /gene_synonym="BD-10; Defb7"
                     /note="defensin beta 10"
                     /db_xref="GeneID:246085"
                     /db_xref="MGI:MGI:2179205"
     exon            1..88
                     /gene="Defb10"
                     /gene_synonym="BD-10; Defb7"
                     /inference="alignment:Splign:2.1.0"
     CDS             28..249
                     /gene="Defb10"
                     /gene_synonym="BD-10; Defb7"
                     /function="antimicrobial peptide"
                     /note="beta-defensin 10"
                     /codon_start=1
                     /product="beta-defensin 10 precursor"
                     /protein_id="NP_631971.1"
                     /db_xref="CCDS:CCDS40285.1"
                     /db_xref="GeneID:246085"
                     /db_xref="MGI:MGI:2179205"
                     /translation="MRTLCSLLLICCLLFSYTTPAVGDLKHLILKAQLTRCYKFGGFC
                     HYNICPGNSRFMSNCHPENLRCCKNIKQF"
     exon            89..298
                     /gene="Defb10"
                     /gene_synonym="BD-10; Defb7"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggagtctgag tgccctttct accagccatg aggactctct gctctctgct gctgatatgc
       61 tgcctccttt tctcatatac caccccagct gttggagatc taaaacatct tatactcaaa
      121 gcacaactta cacggtgcta caagttcgga gggttctgtc actataatat ttgtcctggt
      181 aatagcaggt ttatgagtaa ctgtcaccca gagaatctcc gctgttgcaa gaacataaaa
      241 caattttaag gaagcacatg gaagtcaagt gacagatgtg taactgattt ttaataaa
//
