LOCUS       NM_007848                419 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus defensin, alpha, 31 (Defa31), mRNA.
ACCESSION   NM_007848
VERSION     NM_007848.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Amid,C., Rehaume,L.M., Brown,K.L., Gilbert,J.G., Dougan,G.,
            Hancock,R.E. and Harrow,J.L.
  TITLE     Manual annotation and analysis of the defensin gene cluster in the
            C57BL/6J mouse reference genome
  JOURNAL   BMC Genomics 10, 606 (2009)
   PUBMED   20003482
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Hornef,M.W., Putsep,K., Karlsson,J., Refai,E. and Andersson,M.
  TITLE     Increased diversity of intestinal antimicrobial peptides by
            covalent dimer formation
  JOURNAL   Nat Immunol 5 (8), 836-843 (2004)
   PUBMED   15235601
REFERENCE   3  (bases 1 to 419)
  AUTHORS   Huttner,K.M. and Ouellette,A.J.
  TITLE     A family of defensin-like genes codes for diverse cysteine-rich
            peptides in mouse Paneth cells
  JOURNAL   Genomics 24 (1), 99-109 (1994)
   PUBMED   7896294
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC166039.6.
            
            On Jul 23, 2009 this sequence version replaced NM_007848.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CB934433.1, BE138044.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849376
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-213               AC166039.6         5192-5404           c
            214-419             AC166039.6         4427-4632           c
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 10.35 cM"
     gene            1..419
                     /gene="Defa31"
                     /gene_synonym="CRS4C-2; CRS4C2; CRS4C2b; CRS4C2c; CRS4C2d;
                     CRS4C3a; CRS4C3a2; CRS4C3b; CRS4C3c; CRS4C3d; CRS4C3e;
                     Defa-rs7; Defa23; Defcr-rs7; Defcr23"
                     /note="defensin, alpha, 31"
                     /db_xref="GeneID:13226"
                     /db_xref="MGI:MGI:102509"
     exon            1..213
                     /gene="Defa31"
                     /gene_synonym="CRS4C-2; CRS4C2; CRS4C2b; CRS4C2c; CRS4C2d;
                     CRS4C3a; CRS4C3a2; CRS4C3b; CRS4C3c; CRS4C3d; CRS4C3e;
                     Defa-rs7; Defa23; Defcr-rs7; Defcr23"
                     /inference="alignment:Splign:2.1.0"
     CDS             42..323
                     /gene="Defa31"
                     /gene_synonym="CRS4C-2; CRS4C2; CRS4C2b; CRS4C2c; CRS4C2d;
                     CRS4C3a; CRS4C3a2; CRS4C3b; CRS4C3c; CRS4C3d; CRS4C3e;
                     Defa-rs7; Defa23; Defcr-rs7; Defcr23"
                     /note="defensin-related cryptdin-related sequence 7;
                     alpha-defensin-related sequence 7; cryptdin related
                     sequence peptide; cryptdin-related protein 4C-2; defensin,
                     alpha, related sequence 7; Alpha-defensin 23;
                     alpha-defensin 31"
                     /codon_start=1
                     /product="alpha-defensin 31 precursor"
                     /protein_id="NP_031874.2"
                     /db_xref="CCDS:CCDS52505.1"
                     /db_xref="GeneID:13226"
                     /db_xref="MGI:MGI:102509"
                     /translation="MKTLVLLSALILLAFQVQADPIQNTDEETKTEEQPGKEDQAVSV
                     SFGDPEGSSLQEESLRDLVCYCRTRGCKRRERMNGTCRKGHLIYTLCCR"
     exon            214..419
                     /gene="Defa31"
                     /gene_synonym="CRS4C-2; CRS4C2; CRS4C2b; CRS4C2c; CRS4C2d;
                     CRS4C3a; CRS4C3a2; CRS4C3b; CRS4C3c; CRS4C3d; CRS4C3e;
                     Defa-rs7; Defa23; Defcr-rs7; Defcr23"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 attgggctcc tgctcaccaa tcctccaggt gactcccagc catgaagaca ctagtcctcc
       61 tctctgccct catcctgctg gccttccagg tccaggctga tcctatccaa aacacagatg
      121 aagagactaa aactgaggag cagccaggga aagaggacca ggctgtgtct gtctcttttg
      181 gagacccaga aggctcttct cttcaagagg aatcgttgag agatctggta tgctattgta
      241 gaacaagagg ctgcaaaaga agagaacgca tgaatgggac ctgcagaaag ggtcatttaa
      301 tatacacgct ctgctgtcgc tgaacatgga gaccacagag gacaagacga gcatgagtac
      361 tgaggccact gatgctggtg cctgatgacc acttctcaat aaattgttcg caatatgct
//
