LOCUS       NM_207658                419 bp    mRNA    linear   ROD 03-JUN-2024
DEFINITION  Mus musculus defensin, alpha, 22 (Defa22), mRNA.
ACCESSION   NM_207658 NM_001012308 XM_356134
VERSION     NM_207658.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Amid,C., Rehaume,L.M., Brown,K.L., Gilbert,J.G., Dougan,G.,
            Hancock,R.E. and Harrow,J.L.
  TITLE     Manual annotation and analysis of the defensin gene cluster in the
            C57BL/6J mouse reference genome
  JOURNAL   BMC Genomics 10, 606 (2009)
   PUBMED   20003482
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Patil,A., Hughes,A.L. and Zhang,G.
  TITLE     Rapid evolution and diversification of mammalian alpha-defensins as
            revealed by comparative analysis of rodent and primate genes
  JOURNAL   Physiol Genomics 20 (1), 1-11 (2004)
   PUBMED   15494476
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK008589.1, AC166039.6 and AV067993.1.
            
            On Apr 10, 2010 this sequence version replaced NM_207658.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK008589.1, BY708481.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849377
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-46                AK008589.1         2-47
            47-79               AC166039.6         34622-34654         c
            80-415              AK008589.1         81-416
            416-419             AV067993.1         179-182
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 10.35 cM"
     gene            1..419
                     /gene="Defa22"
                     /gene_synonym="Defcr22"
                     /note="defensin, alpha, 22"
                     /db_xref="GeneID:382059"
                     /db_xref="MGI:MGI:3639039"
     exon            1..215
                     /gene="Defa22"
                     /gene_synonym="Defcr22"
                     /inference="alignment:Splign:2.1.0"
     CDS             44..325
                     /gene="Defa22"
                     /gene_synonym="Defcr22"
                     /note="alpha-defensin 22; defensin-related cryptdin-22"
                     /codon_start=1
                     /product="alpha-defensin 22 precursor"
                     /protein_id="NP_997541.2"
                     /db_xref="CCDS:CCDS40267.1"
                     /db_xref="GeneID:382059"
                     /db_xref="MGI:MGI:3639039"
                     /translation="MKTLVLLSALILLAYQVQTDPIQNTDEETNTEEQPGEEDQAVSV
                     SFGGQEGSALHEKLSRDLICLCRKRRCNRGELFYGTCAGPFLRCCRRRR"
     exon            216..419
                     /gene="Defa22"
                     /gene_synonym="Defcr22"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 acattgggct cctgctcacc aatcctccag gtgactccca gccatgaaga cacttgtcct
       61 cctctctgcc ctcatcctgc tggcctacca ggtccagact gatcctatcc aaaacacaga
      121 tgaagagact aatactgagg agcagccagg ggaagaggac caggctgtgt ctgtctcctt
      181 tggaggccaa gaaggatctg ctcttcatga aaaattgtcg agagatctga tctgcctttg
      241 tagaaaacgt cgctgcaata gaggagaact attttatggg acctgcgcag gacctttttt
      301 gcgctgctgc cgccgccgcc gctgagagtg cagatgacaa agatatgaca accatcagct
      361 ctgaggccac tgatgctggg gcctgatgaa cacttctcaa taaattgttt gcaatatgc
//
