LOCUS       NM_026500               2228 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus DEAD box helicase 59 (Ddx59), mRNA.
ACCESSION   NM_026500 XM_994847 XM_994882
VERSION     NM_026500.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2228)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2228)
  AUTHORS   Shamseldin,H.E., Rajab,A., Alhashem,A., Shaheen,R., Al-Shidi,T.,
            Alamro,R., Al Harassi,S. and Alkuraya,F.S.
  TITLE     Mutations in DDX59 implicate RNA helicase in the pathogenesis of
            orofaciodigital syndrome
  JOURNAL   Am J Hum Genet 93 (3), 555-560 (2013)
   PUBMED   23972372
  REMARK    GeneRIF: These data strongly implicate DDX59 RNA helicase family
            member in the pathogenesis of orofaciodigital syndrome.
REFERENCE   3  (bases 1 to 2228)
  AUTHORS   Quina,L.A., Wang,S., Ng,L. and Turner,E.E.
  TITLE     Brn3a and Nurr1 mediate a gene regulatory pathway for habenula
            development
  JOURNAL   J Neurosci 29 (45), 14309-14322 (2009)
   PUBMED   19906978
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK004833.1 and AK133731.1.
            
            On Jul 1, 2010 this sequence version replaced NM_026500.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK133731.1, AK004833.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849380
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2159              AK004833.1         2-2160
            2160-2228           AK133731.1         2122-2190
FEATURES             Location/Qualifiers
     source          1..2228
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 59.73 cM"
     gene            1..2228
                     /gene="Ddx59"
                     /gene_synonym="1210002B07Rik; 4833411G06Rik"
                     /note="DEAD box helicase 59"
                     /db_xref="GeneID:67997"
                     /db_xref="MGI:MGI:1915247"
     exon            1..153
                     /gene="Ddx59"
                     /gene_synonym="1210002B07Rik; 4833411G06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            154..968
                     /gene="Ddx59"
                     /gene_synonym="1210002B07Rik; 4833411G06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            969..1136
                     /gene="Ddx59"
                     /gene_synonym="1210002B07Rik; 4833411G06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1137..1226
                     /gene="Ddx59"
                     /gene_synonym="1210002B07Rik; 4833411G06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1227..1478
                     /gene="Ddx59"
                     /gene_synonym="1210002B07Rik; 4833411G06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1479..1631
                     /gene="Ddx59"
                     /gene_synonym="1210002B07Rik; 4833411G06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1632..1760
                     /gene="Ddx59"
                     /gene_synonym="1210002B07Rik; 4833411G06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1761..2228
                     /gene="Ddx59"
                     /gene_synonym="1210002B07Rik; 4833411G06Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2146..2151
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ddx59"
                     /gene_synonym="1210002B07Rik; 4833411G06Rik"
                     /note="hexamer: AATAAA"
     polyA_site      2164
                     /gene="Ddx59"
                     /gene_synonym="1210002B07Rik; 4833411G06Rik"
                     /note="major polyA site"
ORIGIN      
        1 ccagatgaag ctccgcctcc cgctgtgcgc aggcgcgggg ccctcaaacc ctggctggga
       61 ttgcggagct tcccggctac tcggccggaa actcggccct gcgcctggac cggagcggcc
      121 cgagcgggaa cggacgcggc ccggtccgcg cggaatgttg aagaatgttt gttccaagat
      181 ctttgaaaat caagaggagt tctaatgatg acctcaaaag cggtgaagct aaaaaaagca
      241 agccagaagc aggaggcctt caggtggagg gagacagaga tactccggtc cacacatcag
      301 tcactgagga agctgtcaca gcagacaagc ccggccatgc atcaagcacc aacagtcctt
      361 cttgccagtt ggctgaggtt tcttccacag gacctgatga gggtgtgaag gacagccacc
      421 catctgaaga gcctgtaaag tcgttttcta aaacccagcg gtggccagag cctggggagc
      481 ctgtatgtgt cgtctgcggt cgttatggag agtatatctg tgacaagacg gacgaagacg
      541 tgtgtagctt ggagtgcaaa gcgaagcatc tgctacaagt taaggaaggg gaaggatcat
      601 taagacccag cagcccacag agagtggctg ccgagccaga gtccccactg gatgcctttt
      661 atgtctacaa agagcacccc tttattgtga ccctcaagga ggaccagatt gaaaccctta
      721 aacagcagct aggaatctca gttcaaggac aagacgttgc caggcccatt atcgacttcg
      781 agcactgtgg cttccctgag accttaaatc agaacttgaa gaaatcaggc tacgaagtgc
      841 caacccccat ccagatgcag atgattcctg tggggctcct gggaagggac attctggcca
      901 gcgctgacac tggctcaggg aaaacagctg cttttctcct gcctgttatt atccgagctt
      961 tctctgagga taaaactcca tccgcactca ttctcacacc gacaagagaa ctggccattc
     1021 agatagagag gcaggccaag gaactgatga gtggtctgcc tcgcatgaag acagtgcttc
     1081 tcgtaggggg cttacctctg cccccacagc tctatcgctt acggcagcat gttaaggtta
     1141 tcatagcaac ccctggacga cttctggata taattaaaca gagctccgta tcactcagtg
     1201 gcataaaaat tgtcgtagta gacgaagctg acaccatgtt gaagatgggc tttcagcagc
     1261 aagtgcttga cgttttggaa cacactcctg gtgactgtca gaccatcttg gtttctgcca
     1321 ccattccaga tagcatagaa cagctcacag accagcttct gcataatcct gtgaggatca
     1381 tcactgggga caagaacctg ccctgcgcca gtgtgcggca gatcatcctg tgggtagaag
     1441 acccagctaa aaagaagaaa ttatttgaaa tcctaaatga tcagaagctc tttaagcctc
     1501 cagtgttagt attcgtggac tgcaaactag gcgcagatct gttgagcgag gcggttcaga
     1561 agatcacagg tctgaacagc acatccatcc actcagagaa gtctcaggtg gaaaggaggg
     1621 acatcctgaa gggattactg gaaggagact atgaggtcgt ggtgagcacg ggggtcctgg
     1681 gtcggggcct agacttggtc aacgtcaagc tggttgtgaa ttttgatatg ccttcaagca
     1741 tggatgagta tgtgcaccag gttggcagag ttgggagact cggtcaaaat ggaactgcaa
     1801 tcacattcat caataacaac tctaaaagac tcttctggga tgttgccaaa agagtgaagc
     1861 ccacgggatc cattctcccg ccacagctat taaattcccc ttaccttcat gagcagaaga
     1921 gaaaggaaca gcagaaagac agacagacac agaacagcct ggtcacgggg gccaacctca
     1981 tggacattat taggaaacac gaaaagagca gttcacagaa atgacctggt ctgtcatttc
     2041 ccatgggctt gttatgcgtt atcaccaaaa tttctaataa tactgtatga cctagtcaat
     2101 aaacttggac aaggacagaa gactctataa gatcttttta aatttaataa aatttataca
     2161 gcaatatcgt tatttatttc agtccttgta ttttaaaaac aaaatcagaa ggtgagttgc
     2221 taacagtg
//
