LOCUS       NM_026409               2818 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus DEAD box helicase 55 (Ddx55), transcript variant 1,
            mRNA.
ACCESSION   NM_026409
VERSION     NM_026409.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2818)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2818)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2818)
  AUTHORS   Jerome-Majewska,L.A., Achkar,T., Luo,L., Lupu,F. and Lacy,E.
  TITLE     The trafficking protein Tmed2/p24beta(1) is required for
            morphogenesis of the mouse embryo and placenta
  JOURNAL   Dev Biol 341 (1), 154-166 (2010)
   PUBMED   20178780
REFERENCE   4  (bases 1 to 2818)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Koseki,H., Hiraoka,S.,
            Saga,Y., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: III. the complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (4), 167-180 (2003)
   PUBMED   14621295
REFERENCE   5  (bases 1 to 2818)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY202366.1, AK033741.1 and BC043052.1.
            
            On Jul 1, 2010 this sequence version replaced NM_026409.3.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK129402.1, AK077525.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN00849384
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            RefSeq Select criteria           :: based on conservation,
                                                expression, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-24                BY202366.1         2-25
            25-2050             AK033741.1         2-2027
            2051-2818           BC043052.1         1989-2756
FEATURES             Location/Qualifiers
     source          1..2818
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 63.66 cM"
     gene            1..2818
                     /gene="Ddx55"
                     /gene_synonym="2810021H22Rik; mKIAA1595"
                     /note="DEAD box helicase 55"
                     /db_xref="GeneID:67848"
                     /db_xref="MGI:MGI:1915098"
     exon            1..176
                     /gene="Ddx55"
                     /gene_synonym="2810021H22Rik; mKIAA1595"
                     /inference="alignment:Splign:2.1.0"
     CDS             69..1871
                     /gene="Ddx55"
                     /gene_synonym="2810021H22Rik; mKIAA1595"
                     /EC_number="3.6.4.13"
                     /note="isoform 1 is encoded by transcript variant 1;
                     ATP-dependent RNA helicase DDX55; DEAD box protein 55;
                     DEAD (Asp-Glu-Ala-Asp) box polypeptide 55"
                     /codon_start=1
                     /product="ATP-dependent RNA helicase DDX55 isoform 1"
                     /protein_id="NP_080685.2"
                     /db_xref="CCDS:CCDS39281.1"
                     /db_xref="GeneID:67848"
                     /db_xref="MGI:MGI:1915098"
                     /translation="MEHVTEGAWESLQVPLHPRVLGALRELGFPHMTPVQSATIPLFM
                     KNKDVAAEAVTGSGKTLAFVIPILEILLRREEKLKKNQVGAIVITPTRELAIQIDEVL
                     SHFTKHFPQFSQILWIGGRNPGEDVERFKQHGGNIIVATPGRLEDMFRRKAEGLDLAS
                     CVKSLDVLVLDEADRLLDMGFEASINTILEFLPKQRRTGLFSATQTQEVENLVRAGLR
                     NPVRISVKEKGVAASSTQKTPSRLENHYMICKADEKFNQLVHFLRSRQQEKHLVFFST
                     CACVEYYGKALEALLKKVKILCIHGKMKYKRNKIFMEFRKLQSGILVCTDVMARGIDI
                     PEVNWVLQYDPPSNASAFVHRCGRTARIGHGGSALVFLLPMEEAYINFLAINQKCPLQ
                     EMSLQRNTIDLLPKLRAMALADRAVFEKGMKAFVSFVQAYAKHECSLIFRLKDLDFAG
                     LARGFALLRMPRMPELRGKQFPDFVPVDIDTDTIPFKDKIREKQRQKLLEQKRKERSE
                     NEGRKKFIKNKAWSKQKAKKERKKKMNAKRKKDEGSDIDDEDMEELLNDTRLLKKFKK
                     GKITEEEFEKGLLTSAKRTVQLTDLGVSDLEEDS"
     exon            177..227
                     /gene="Ddx55"
                     /gene_synonym="2810021H22Rik; mKIAA1595"
                     /inference="alignment:Splign:2.1.0"
     exon            228..314
                     /gene="Ddx55"
                     /gene_synonym="2810021H22Rik; mKIAA1595"
                     /inference="alignment:Splign:2.1.0"
     exon            315..406
                     /gene="Ddx55"
                     /gene_synonym="2810021H22Rik; mKIAA1595"
                     /inference="alignment:Splign:2.1.0"
     exon            407..469
                     /gene="Ddx55"
                     /gene_synonym="2810021H22Rik; mKIAA1595"
                     /inference="alignment:Splign:2.1.0"
     exon            470..619
                     /gene="Ddx55"
                     /gene_synonym="2810021H22Rik; mKIAA1595"
                     /inference="alignment:Splign:2.1.0"
     exon            620..809
                     /gene="Ddx55"
                     /gene_synonym="2810021H22Rik; mKIAA1595"
                     /inference="alignment:Splign:2.1.0"
     exon            810..892
                     /gene="Ddx55"
                     /gene_synonym="2810021H22Rik; mKIAA1595"
                     /inference="alignment:Splign:2.1.0"
     exon            893..1024
                     /gene="Ddx55"
                     /gene_synonym="2810021H22Rik; mKIAA1595"
                     /inference="alignment:Splign:2.1.0"
     exon            1025..1117
                     /gene="Ddx55"
                     /gene_synonym="2810021H22Rik; mKIAA1595"
                     /inference="alignment:Splign:2.1.0"
     exon            1118..1232
                     /gene="Ddx55"
                     /gene_synonym="2810021H22Rik; mKIAA1595"
                     /inference="alignment:Splign:2.1.0"
     exon            1233..1401
                     /gene="Ddx55"
                     /gene_synonym="2810021H22Rik; mKIAA1595"
                     /inference="alignment:Splign:2.1.0"
     exon            1402..1694
                     /gene="Ddx55"
                     /gene_synonym="2810021H22Rik; mKIAA1595"
                     /inference="alignment:Splign:2.1.0"
     exon            1695..2799
                     /gene="Ddx55"
                     /gene_synonym="2810021H22Rik; mKIAA1595"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2094..2099
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ddx55"
                     /gene_synonym="2810021H22Rik; mKIAA1595"
                     /note="hexamer: ATTACA"
     polyA_site      2112
                     /gene="Ddx55"
                     /gene_synonym="2810021H22Rik; mKIAA1595"
                     /note="major polyA site"
     regulatory      2777..2782
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ddx55"
                     /gene_synonym="2810021H22Rik; mKIAA1595"
                     /note="hexamer: AATAAA"
     polyA_site      2799
                     /gene="Ddx55"
                     /gene_synonym="2810021H22Rik; mKIAA1595"
ORIGIN      
        1 agttcattct gtcgatgctt ctgcagcgtt gcgggcgact gaaacccgca gagaaccggg
       61 gacgcgccat ggagcacgtg acggagggtg cctgggagtc gctgcaggtg ccgctgcacc
      121 ctcgggtgct cggtgcactg cgcgagttgg gcttcccgca catgacgccg gtgcagtctg
      181 ccaccatccc tctgttcatg aaaaacaaag atgttgccgc agaggctgtg acaggtagtg
      241 ggaaaaccct ggcttttgtt atccccattc tggagattct tctgagaagg gaggagaagt
      301 taaagaagaa ccaggtagga gccatcgtca tcaccccgac tcgcgagctg gccattcaga
      361 ttgatgaagt cctgtcacac ttcacgaagc actttccgca gttcagccag attttgtgga
      421 ttggaggccg gaaccctgga gaagatgtgg agaggttcaa gcagcacggt gggaacatca
      481 ttgtggcaac ccctgggcgc ctggaggaca tgttccggag gaaggctgag ggtctggacc
      541 tggccagctg tgtgaagagc ttggatgtgc tggtgctgga cgaggcagac agactgctcg
      601 acatgggctt tgaggcaagc ataaacacaa tcctggagtt tttgccaaag cagagaagaa
      661 caggcctctt ctcagccacg cagacacagg aagtggagaa cttagtgcga gcaggcctcc
      721 ggaaccctgt ccgaatctct gtgaaggaga agggtgtggc agccagcagt acccagaaga
      781 ccccgtcccg cctggagaac cactatatga tctgtaaggc agatgagaaa ttcaaccagc
      841 tggtccattt ccttcggagc cgtcagcagg agaagcacct ggtcttcttc agcacgtgtg
      901 cgtgtgtgga atactatggg aaggccctgg aggcgctgtt gaagaaagtg aagatcctgt
      961 gcatccacgg gaagatgaag tacaagcgca ataagatctt catggagttc cgcaagctgc
     1021 agagtgggat cctggtgtgc actgacgtga tggcccgggg aattgatatt cccgaagtaa
     1081 actgggtttt gcagtatgac cctcccagca atgccagtgc cttcgtgcat cgatgtggac
     1141 gcacagcccg cattggccac ggtggcagtg ccctggtgtt cctgctgccc atggaggagg
     1201 cctacatcaa cttcttggcc atcaaccaga aatgccccct gcaggagatg agcctccaga
     1261 gaaacaccat agaccttctg ccgaagctcc gggccatggc tctggctgac agagctgtgt
     1321 tcgagaaggg catgaaagcc tttgtgtcct ttgtgcaggc ttatgcgaag cacgagtgca
     1381 gcctcatctt ccggctgaag gatcttgact ttgccgggct tgctcgaggc tttgccctgc
     1441 tcaggatgcc caggatgcca gagctaaggg ggaagcagtt tcctgacttt gtaccagtgg
     1501 acatcgatac cgacaccatt ccatttaaag ataaaattag agaaaaacag aggcagaaac
     1561 ttctggaaca aaaaagaaaa gagaggtcag aaaatgaagg gaggaaaaaa ttcatcaaaa
     1621 ataaagcttg gtcgaagcag aaggccaaaa aggaaaggaa gaagaagatg aatgcaaaga
     1681 ggaagaagga tgagggttct gatattgacg atgaagacat ggaggaactc cttaatgata
     1741 caaggctctt gaagaaattt aaaaaaggta aaatcacaga agaagaattt gagaaggggc
     1801 tgttgacaag tgccaaaagg acagtccagc tgacagattt aggtgtctca gacttggaag
     1861 aggacagttg acctcagagc ctcaggtgaa ggtcacctca ctggccctac attcctgctc
     1921 ttgctatctg gaaagctgtc tgttcagact gggagaacct gaaggactgc acacacggga
     1981 ctatgagact accagaatct cacagaaatg tgttttacta tttgaatgta aataacagat
     2041 ttcagtattt attttgatta attatgtttt ttctaggatg gtttttgtgc tttattacag
     2101 acttaaaatg tgtgtgtgtg tgtaattcct attcctttta agacagataa ggaagtatac
     2161 ttgattttag gcctggaaaa gtttctaagc atttattccc aggcacttga catccccttg
     2221 cctgctccca cccaaatgtc gcatatcctt tgtattccta ccgagagcac ccacagaggc
     2281 agagggcctg tgtgcagggt ttccctcccc cccccttttc attgtaatag ggctacacta
     2341 ctgtagcggt ttgcatatac ttggtccata ggaagcggca ctattagatg tggccttgta
     2401 gaaaatgtgt catggtggag gcaggctttg aggtttccta ggctcaagtg ccacccagtg
     2461 tgtgggagaa agcctcctgg ctgcttttgg gtcaggatgt agaagtctgg gcctctccag
     2521 ccccacatct gcctgcatac taccatgctt cccaccctta tagcctaaat ctctgcaact
     2581 gttagccagc cccaattcaa tgtttgcctt tgtaagagtt gccttggcca ggcagtggtg
     2641 gcgtacacct ttaatcccag caccagggag acagaggcag gtggatttct gagtttgagg
     2701 ccagcctggt ctacagagtg agttccggga cagccaggac tgcacagaga aaccctgtct
     2761 cgaaaaacaa aaacaaaata aaaagaaatt tcatacataa aaaaaaaaaa aaaaaaaa
//
